Heterociclos com Nitrogénio (N)

The drug, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride (CGP 46660), is a competitive antagonist at the human histamine H3 receptor. It has been shown to bind to the histamine H3 receptor in the range of 0.001 to 1 μM and is selective for this receptor over other receptors. CGP 46660 is an optical sensor that can be used in titration calorimetry experiments to measure changes in heat production when it binds to histamine H3 receptors. The drug also has been shown to inhibit guanine nucleotide-binding protein (G protein) signaling pathways and brain functions such as memory formation, learning, and attention span. These effects were demonstrated in humans by measuring EEG activity. The optimum concentration of CGP 46660 for these effects was found to be between 0.01 and 10 μM.

Please enquire for more information about 2-Methyl-3-oxo-3,5,6,7-tetrahydro-2H-cyclopenta[c]pyridine-4-carbonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page

a-Tripiperideine is an enolate that can be used as a catalyst to catalyze the formation of carbinols and cyclic compounds. It is also used in the synthesis of trimeric products, such as platelets and erythrocytes. The reaction product of a-tripiperideine with magnesium yields trimerizing agents, which are used in the production of vinylene.

2-Chloro-3-hydroxypyridine is a reactive chemical that can be synthesized from hydrochloric acid and ammonia. It has a high melting point, which is an indication of its strength. 2-Chloro-3-hydroxypyridine has been used in the kinetic and population growth studies for bacteria. The reaction of 2-chloro-3-hydroxypyridine with sodium hydrogen is exothermic and has a red shift, which indicates that the activation energy for this reaction is low. Activation energies are important because they indicate the stability of molecules.

Please enquire for more information about 1-{2-(4-Chlorophenyl)-7-[(E)-2-(dimethylamino)vinyl][1,2,4]triazolo[1,5-a]pyrimidin-6-yl}ethanone including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Applications Intermediate for heterocyclic compounds as tyrosine kinase inhibitors and anticancer agents. References McLean, A., et al.: J. Chem. Phys., 72, 5639 (1980), Watts, J., et al.: J. Biol. Chem., 276, 43197 (2001),

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5-Bromo-2-iodopyrimidine is a nitrogen heterocycle that has been found to have potential for use in the treatment of cancer. It is an asymmetric synthesis product of the photophysical reaction, which can be achieved by using an in vivo model. The compound's structure was determined by X-ray crystallography and nuclear magnetic resonance spectroscopy, and it has been shown to have a formyl group with a palladium-catalyzed cross-coupling reaction. 5-Bromo-2-iodopyrimidine can also be used as an acceptor molecule for the potential therapy of cancer. The optical properties of this compound are also noteworthy, with absorption maxima at 330 nm and emission maxima at 385 nm.

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