Éteres

5,5-Diethoxypentanal is an aldehyde that has a variety of uses in the synthetic chemistry, chemical biology and biotechnology fields. It is used for the synthesis of biomolecules and can be used as a precursor for formylation reactions. 5,5-Diethoxypentanal can also be immobilized onto silicone surfaces to create devices that are sensitive to temperature changes. The formyl group in 5,5-diethoxypentanal is covalently immobilized onto the silicone surface via an amide linkage. This provides a stable system that can be used at temperatures up to 400 °C.

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2-Methoxy-5-nitrobenzaldehyde is an amine that has been shown to be a potent anticancer agent. It is synthesized by the cross-coupling of 2,4,6-trimethoxyphenylacetonitrile with an amine. This compound has been shown to induce apoptosis in cancer cells by binding to DNA and inhibiting protein synthesis. 2-Methoxy-5-nitrobenzaldehyde also induces the M2 phenotype in macrophages and induces the production of fluorescent ethyl cinnamate from dihydrobenzofuran. The cross-coupling reaction is photolabile, making it difficult to study the mechanism of this compound's anticancer activity.

5-Methoxy-1-methyl-1H-indole-3-carbaldehyde is a synthetic compound that has been shown to inhibit the growth of human tumour cells in vitro. This compound is a regioisomeric mixture of two enantiomers, with the (S) isomer being the more potent inhibitor. The (R) isomer was found to be less active against human tumour cells and may have an antimicrobial activity. 5-Methoxy-1-methyl-1H-indole-3-carbaldehyde has been shown to be bioreductive towards electron donors such as NADPH and glutathione. It also inhibits dt diaphorase and aerobic metabolism in human tumour cells.