Antiparasitários
Os antiparasitários são compostos projetados para tratar e prevenir infecções parasitárias, inibindo o crescimento e a sobrevivência dos parasitas. Esta categoria inclui uma variedade de agentes antiparasitários destinados exclusivamente ao uso em laboratório e não para consumo humano. Estes produtos são essenciais para fins de pesquisa, permitindo que cientistas estudem os ciclos de vida dos parasitas, mecanismos de ação e o desenvolvimento de resistência. O uso de antiparasitários em ambientes laboratoriais auxilia na descoberta e otimização de novos tratamentos para doenças parasitárias, contribuindo para os avanços na parasitologia médica e veterinária. Pesquisadores dependem desses produtos para aprimorar sua compreensão sobre infecções parasitárias e desenvolver terapias mais eficazes.
Produtos da "Antiparasitários"
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(±)-Atovaquone Impurity C
CAS:Produto ControladoImpurity Atovaquone EP Impurity C, Atovaquone USP Related Compound A Applications (±)-Atovaquone Impuriyy C (Atorvastatin EP Impurity C), is the impurity of Atovaquone (A793500), which belongs to the class of naphthoquinones, that inhibits mitochondrial electron transport. It is an Antipneumocystic. References Hudson, A.T., et al.: Drugs Exp. Clin. Res., 17, 427 (1991), Fry, M., et al.: Biochem. Pharmacol., 43, 1545 (1992), El-Sadr, W.M., et al.: N. Engl. J. Med., 339, 1889 (1998),Fórmula:C22H17ClO3Cor e Forma:Light YellowPeso molecular:364.82Dixanthogen
CAS:Dixanthogen (Auligen) is an ectoparasiticide. Dixanthogen is a thiocarbonyl compound.Fórmula:C6H10O2S4Pureza:95% - 98%Cor e Forma:SolidPeso molecular:242.4Pentamidine dihydrochloride
CAS:Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (Fórmula:C19H26Cl2N4O2Pureza:98.58%Cor e Forma:SolidPeso molecular:413.34(E)-Cefodizime
CAS:Applications (E)-Cefodizime can be obtained from Ethyl Acetate (E899545) which is a chemical intermediate used in the production of various analgesics, antibiotics and antimalarial agents. References Mutti, F.G., et al.: Adv. Syn. Cata., 354, 3409 (2012); Subudhi, B., et al.: Bull. Chem. Soc., Ethiopia., 26, 455 (2012);Fórmula:C20H20N6O7S4Pureza:>80%Cor e Forma:NeatPeso molecular:584.6688Tinidazole
CAS:Fórmula:C8H13N3O4SPureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:247.27Antileishmanial agent-24
Antileishmanial agent-24 (compound 33) exhibits antileishmanial activity, demonstrating an inhibitory concentration 50 (IC50) value of 5.39 μM againstFórmula:C34H29Cl4N3O2Pureza:98%Cor e Forma:SolidPeso molecular:653.427-Chloro-4-(2-methyl-1-pyrrolidinyl)-quinoline
CAS:Produto ControladoFórmula:C14H15ClN2Cor e Forma:NeatPeso molecular:246.74Conoidin A
CAS:Conoidin A is a cell permeable inhibitor of T.Fórmula:C10H8Br2N2O2Pureza:98.00%Cor e Forma:SolidPeso molecular:347.99INE963
CAS:INE963: Potent against Pf 3D7 (EC50=6nM), clears parasites in <24h; effective on P. falciparum/vivax isolates (EC50=0.01-7nM).Fórmula:C19H26N6O2SPureza:99.04%Cor e Forma:SolidPeso molecular:402.51(2R,3R)-Benzhydryl 2,3-bis(benzyloxy)-4-hydroxybutanoate
Produto ControladoApplications (2R,3R)-Benzhydryl 2,3-bis(benzyloxy)-4-hydroxybutanoate is an intermediate in synthesizing 4-Phospho D-Erythronate (P355000), which is an intermediate in the synthesis of pyridoxal 5'-phosphate in some bacteria and an inhibitor of ribose 5-phosphate isomerase. Phosphorylated aldonic acids are strong inhibitors of 6-phosphogluconate dehydrogenase, and 4-phospho-D-erythronate (4PE) and 4-phospho-D-erythronohydroxamate are two of the strongest inhibitors of the Trypanosoma brucei enzyme. References Tanaka, N., et al.: J. Mol. Biol., 324, 519 (2002); Fitzpatrick, T., et al.: Biochem. J., 407, 1 (2007); Kalliri, E., et al.: J. Bacteriol., 190, 3793 (2008)Fórmula:C31H30O5Cor e Forma:NeatPeso molecular:482.567Insecticidal agent 16
CAS:Insecticidal agent 16 (compound A21) exhibits insecticidal activity against Plutella xylostella, with LC50 values of 1.2 and 13.2 µg/mL respectively.Fórmula:C21H13Cl2F6N5O2SCor e Forma:SolidPeso molecular:584.32Ac-Atovaquone
CAS:Ac-Atovaquone, an ester-acetylated derivative of atovaquone, acts as a potent inhibitor of cytochrome bc1 (cytochrome bc1). This compound shows potential for use in malaria research.Fórmula:C24H21ClO4Cor e Forma:SolidPeso molecular:408.87Bacopasaponin C
CAS:Bacopasaponin C may have antioxidant activity, it also shows anti-leishmanial property.Fórmula:C46H74O17Pureza:97.85%Cor e Forma:SolidPeso molecular:899.074-Amino-1-pentanol-d4 Benzyl Ether
Produto ControladoApplications 4-Amino-1-pentanol-d4 Benzyl Ether is an intermediate in the synthesis of Hydroxychloroquine-d4 Sulfate (H916902), which is an antimalarial; antirheumatic; lupus erythematosus suppressant. References Yarden, Y., et al.: Nature, 323, 226 (1986), Seifert, R., et al.: J. Biol. Chem., 264, 8771 (1989), Gahl, W., et al.: Mol. Genet. Metab., 76, 234 (2002), Card, J., et al.: Toxicol. Sci., 75, 169 (2003),Fórmula:C12D4H13NO2Cor e Forma:NeatPeso molecular:211.293Piperaquine-d6 Tetraphosphate
CAS:Produto ControladoApplications Piperaquine-d6, is a 4-aminoquinoline derivative used as an antimalarial agent. Piperaquine interferes with physiological function of the food vacuole membrane of the trophozoites leading to autophagocytosis of the parasites. It is commonly used in combination with Dihydroartemisinin (D448360) for the treatment of multi-drug resistant falciparum malaria. References Nguyen, T.M.T. et al.: Tap Chi Duoc Hoc, 57, 22 (2007); Song, J. et al.: Malaria J., 10, 231 (2011);Fórmula:C29H26D6Cl2N6•4H3PO4Cor e Forma:NeatPeso molecular:933.53Halofuginone
CAS:Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.Fórmula:C16H17BrClN3O3Pureza:97.67%Cor e Forma:Off-White SolidPeso molecular:414.685-(N-Ethyl-N-2-hydroxyethylamino)-2-penthlamine
CAS:Produto ControladoApplications 5-(N-Ethyl-N-2-hydroxyethylamino)-2-penthlamine is a useful synthetic intermediate in the synthesis of Hydroxy Chloroquine (H905300/H905305); a major metabolite of Chloroquine (C379965, diphosphate salt) which is a standard anti-malarial drug. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Brocks, D., et al.: Clin. Pharmacokinet., 42, 1359 (2003); Brocks, D., et al.: Clin. Pharmacokinet., 42, 1359 (2003); Huang, S., et al.: Talanta, 64, 887 (2004); Luthman, H., et al.: Nucleic Acids Res., 11, 1295 (1983); Vezmar, M., et al.: Biochem. Pharmacol., 56, 733 (1998); Krajewski, W.A., et al.: J. Biomol. Struct. Dyn., 16, 1097 (1999)Fórmula:C11H26N2OCor e Forma:NeatPeso molecular:202.337cis-Atovaquone-d5 (contains 10% trans isomer)
CAS:Produto ControladoApplications Cis isomer of Atovaquone-d5.Fórmula:C22H14D5ClO3Cor e Forma:NeatPeso molecular:371.87trans-Clopenthixol dihydrochloride
CAS:Trans-Clopenthixol dihydrochloride ((E)-Clopenthixol dihydrochloride), an antibiotic without neuroleptic effects, has demonstrated in vitro efficacy against Pseudomonas aeruginosa and Plasmodium falciparum, as referenced in [1] [2].Fórmula:C22H27Cl3N2OSPureza:98%Cor e Forma:SolidPeso molecular:473.89Atherosperminine
CAS:Atherosperminine inhibits AChE/BChE and relaxes trachealis via cAMP phosphodiesterase inhibition.Fórmula:C20H23NO2Pureza:99.4%Cor e Forma:SolidPeso molecular:309.4Piperonyl butoxide
CAS:Piperonyl butoxide (Pyrenone 606) is an insecticide synergist, particularly for rotenone and pyrethroids.Fórmula:C19H30O5Pureza:99.84%Cor e Forma:Pale Yellow Liquid Oil LiquidPeso molecular:338.44Antileishmanial agent-21
Antileishmanial agent-21 (compound 4e) functions as an inhibitor of Leishmania pteridine reductase 1 (Lm-PTR1), employing an anti-folate mechanism.Fórmula:C21H16N2O3Pureza:98%Cor e Forma:SolidPeso molecular:344.36UCB7362
CAS:UCB7362 (GLXC-26743) is an orally available and potent plasmepsin X (PMX) inhibitor with anti-malarial activity.UCB7362 inhibits parasite reproduction.Fórmula:C25H26ClN5O3Pureza:97.38%Cor e Forma:SolidPeso molecular:479.963-Aminopropionitrile (Stabilized with K2CO3)
CAS:Produto ControladoFórmula:C3H6N2Cor e Forma:NeatPeso molecular:70.09Eflornithine
CAS:Eflornithine blocks ornithine decarboxylase, treating African trypanosomiasis and female facial hair.Fórmula:C6H12F2N2O2Pureza:99.44% - 99.84%Cor e Forma:SolidPeso molecular:182.17Antileishmanial agent-20
Antileishmanial agent-20 exhibits selectivity against the Leishmania parasite, with IC50 values of 2.8 μM for L.Fórmula:C15H16N4O3Pureza:98%Cor e Forma:SolidPeso molecular:300.31Miltefosine
CAS:Fórmula:C21H46NO4PPureza:>98.0%(T)(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:407.58Kojic acid
CAS:Kojic acid is a fungal metabolite that inhibits tyrosinase, an enzyme involved in melanin synthesis, with an IC50 value of 30.6 μM for mushroom tyrosinase.Fórmula:C6H6O4Pureza:99.34% - 99.72%Cor e Forma:Prismatic Needles From Acetone Ethanol+Ether Or Methanol+Ethyl Acetate Tan PowderPeso molecular:142.11Primaquine
CAS:Primaquine is an antimalarial compound and a gametocytocide, clearing liver schizonts and dormant forms of Plasmodium vivax.Fórmula:C15H21N3OPureza:98.62%Cor e Forma:SolidPeso molecular:259.35Antileishmanial agent-22
Antileishmanial agent-22 (compound 15b) serves as an antiparasitic and antibacterial, exhibiting activities against Leishmania (IC50 = 0.408 μM), malaria, andFórmula:C29H26Cl2N4O3Pureza:98%Cor e Forma:SolidPeso molecular:549.45Osthole
CAS:Osthole (Osthol), a potential inhibitor of histamine H1 receptor, has been shown to stimulate osteoblast proliferation and differentiation.Fórmula:C15H16O3Pureza:99.93% - 99.96%Cor e Forma:Fine White PowderPeso molecular:244.29Brotianide
CAS:Brotianide (BAY-VA4059) has anthelmintic activity and is highly potent against liver fluke and gastric fluke infestations and can be used to treat acute,Fórmula:C15H10Br2ClNO2SPureza:98% - 98.44%Cor e Forma:SolidPeso molecular:463.57(±)-Emodin bianthrone
CAS:(±)-Emodin bianthrone (compound 10), a naturally occurring substance, demonstrates antimalarial, antitubercular, and antifungal properties [1].Fórmula:C30H22O8Pureza:98%Cor e Forma:SolidPeso molecular:510.49Dapsone
CAS:Dapsone (Sulphadione) has activity against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae.Fórmula:C12H12N2O2SPureza:99.84%Cor e Forma:White To Creamy Solid CrystallinePeso molecular:248.3Quinfamide
CAS:Quinfamide is a compound with the potential to treat tropical parasitic infections such as Amoebiasis and Helminthiasis.Fórmula:C16H13Cl2NO4Pureza:98.88%Cor e Forma:SolidPeso molecular:354.18Ref: TM-T16705
1mg50,00€5mg105,00€10mg156,00€25mg255,00€50mg368,00€100mg505,00€200mg692,00€1mL*10mM (DMSO)111,00€SLU-10906
CAS:SLU-10906 (Compound 63) is an orally active inhibitor of Cryptosporidium. It demonstrates activity against the parasite in cell-based infection models with an EC50 of 0.19 μM and exhibits no cytotoxicity. SLU-10906 is a promising candidate for research in cryptosporidiosis.Fórmula:C22H21BFN5O2Cor e Forma:SolidPeso molecular:417.244Tafenoquine Succinate
CAS:Tafenoquine Succinate (WR 238605 (Succinate)) is an 8-aminoquinoline. and is an agent of anti-malarial prophylactic.Fórmula:C28H34F3N3O7Pureza:99.84%Cor e Forma:SolidPeso molecular:581.58Nicarbazin
CAS:Nicarbazin (Nicoxin) is an equimolar complex of 4, 4'-Dinitrocarbanilide and 2-Hydroxy-4, 6-dimethylpyrimidine. A coccidiostat for poultry.Fórmula:C19H18N6O6Pureza:99.54%Cor e Forma:Crystals Yellow Or Greenish Yellow Powder Odorless With A Bit Of SmellPeso molecular:426.38(9Z)-2,7-Dichloro-9-[(4-chlorophenyl)methylene]-α-[(dibutylamino)methyl]-9H-fluorene-4-methanol
CAS:Fórmula:C30H32Cl3NOPureza:98%Cor e Forma:SolidPeso molecular:528.9402Piperaquine phosphate
CAS:Piperaquine phosphate is an antimalarial compound commonly used in combination with artemisinin to inhibit Plasmodium falciparum.Fórmula:C29H32Cl2N6xH3O4PPureza:99.17%Cor e Forma:SolidPeso molecular:535.52(Free base)Azlocillin sodium salt
CAS:Azlocillin sodium, an acylampicillin, is a broad-spectrum antibioticsFórmula:C20H22N5NaO6SPureza:97.63% - 97.63%Cor e Forma:SolidPeso molecular:483.47Cletoquine
CAS:Cletoquine, Hydroxychloroquine's active metabolite, fights CHIKV, has antimalarial properties, and may treat autoimmune diseases.Fórmula:C16H22ClN3OPureza:97.26%Cor e Forma:SolidPeso molecular:307.82Suramin Sodium Salt
CAS:Suramin Sodium Salt (BAY-205) is a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors.Fórmula:C51H34N6Na6O23S6Pureza:97.47% - 99.97%Cor e Forma:WhitePeso molecular:1429.15Antimalarial agent 1
CAS:Antimalarial agent 1 is an effective antimalarial agent.Fórmula:C12H21N6O4PPureza:98.35% - 99.04%Cor e Forma:SolidPeso molecular:344.31Cinchonan-9-ol, 6'-methoxy-, (8α,9R)-
CAS:Fórmula:C20H24N2O2Pureza:97%Cor e Forma:SolidPeso molecular:324.416759999999958304-vs
8304-vs is a macrocyclic anti-Plasmodial compound that irreversibly binds to and inhibits the Plasmodium proteasome, effectively halting the growth ofFórmula:C35H53N5O8SPureza:98%Cor e Forma:SolidPeso molecular:703.89Dithiazanine iodide
CAS:Dithiazanine iodide (Netocyd) is a benzothiazole.Fórmula:C23H23IN2S2Pureza:99% - 99.24%Cor e Forma:SolidPeso molecular:518.48
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