Antiparasitários
Os antiparasitários são compostos projetados para tratar e prevenir infecções parasitárias, inibindo o crescimento e a sobrevivência dos parasitas. Esta categoria inclui uma variedade de agentes antiparasitários destinados exclusivamente ao uso em laboratório e não para consumo humano. Estes produtos são essenciais para fins de pesquisa, permitindo que cientistas estudem os ciclos de vida dos parasitas, mecanismos de ação e o desenvolvimento de resistência. O uso de antiparasitários em ambientes laboratoriais auxilia na descoberta e otimização de novos tratamentos para doenças parasitárias, contribuindo para os avanços na parasitologia médica e veterinária. Pesquisadores dependem desses produtos para aprimorar sua compreensão sobre infecções parasitárias e desenvolver terapias mais eficazes.
Produtos da "Antiparasitários"
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Cletoquine-D4 Oxalate
CAS:Produto ControladoApplications A labelled metabolite of Hydroxychloroquine. References Polet, H., et al.: J. Cell. Physiol., 122, 415 (1985), Gabriel, H., et al.: Eur. J. Immunol., 23, 2704 (1993), Gordon, C., et al.: Br. J. Rheumatol., 35, 226 (1996), Means, T., et al.: J. Clin. Invest., 115, 407 (2005),Fórmula:C18H20D4ClN3O5Cor e Forma:NeatPeso molecular:401.88Artemether
CAS:Fórmula:C16H26O5Pureza:>98.0%(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:298.38Fosravuconazole L-lysine ethanolate
CAS:Fosravuconazole L-lysine ethanolate, a prodrug for ravuconazole, treats onychomycosis in Japan.Fórmula:C31H40F2N7O8PSPureza:95%Cor e Forma:SolidPeso molecular:739.7DSM1465
DSM1465 (Compound 82) is a potent and selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 value of 15 nM. It inhibits P. falciparum 3D7 (Pf3D7) parasites with an EC50 value of 1.4 nM and demonstrates significant in vivo efficacy in humanized P. falciparum mouse models.Fórmula:C17H12ClF6N5O2Cor e Forma:SolidPeso molecular:467.753Primaquine
CAS:Primaquine is an antimalarial agent with action on Plasmodium hypnozoites in the liver and is used for preventing relapses of malaria caused by Plasmodium vivax and Plasmodium ovale.Fórmula:C15H21N3OPureza:Min. 95%Cor e Forma:PowderPeso molecular:259.35 g/molNilutamide
CAS:Nilutamide, a nonsteroidal anti-androgen, treats prostate cancer by blocking androgen receptors, not affecting other hormone receptors.Fórmula:C12H10F3N3O4Pureza:98.45% - 98.67%Cor e Forma:Crystalline SolidPeso molecular:317.22Symetine
CAS:Symetine(L 16726) is a small molecule compound with antiparasitic activity that can be used to study amoebic liver abscesses in guinea pigs.Fórmula:C30H48N2O2Pureza:99.79%Cor e Forma:SolidPeso molecular:468.71Paromomycin Sulfate
CAS:Fórmula:C23H45N5O14·xH2SO4Pureza:>92.0%(HPLC)Cor e Forma:White to Almost white powder to crystalNiclosamide Ethanolamine Salt
CAS:Fórmula:C13H8Cl2N2O4·C2H7NOPureza:>98.0%(T)(HPLC)Cor e Forma:Light yellow to Yellow to Orange powder to crystalPeso molecular:388.20Diazinon
CAS:Diazinon (Dimpylate) is a thiophosphoric acid ester, functioning as a nonsystemic organophosphate insecticide that effectively targets and controls a variety ofFórmula:C12H21N2O3PSPureza:97.79% - 99.89%Cor e Forma:Colorless Oil Ethanol/Xylene/Acetone With A Flash Point In The Range 82-105° FPeso molecular:304.35Menoctone
CAS:Menoctone is an orally effective antimalarial agent that inhibits blood-induced rodent malaria. It enhances the antimalarial effects of chloroquine or quinine, making it useful for malaria research.Fórmula:C24H32O3Cor e Forma:SolidPeso molecular:368.51(R)-Hydroxychloroquine
CAS:Produto ControladoApplications 2-[[(4R)-4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-ethanol is an antimalarial drug more commonly known as (R)-hydroxychloroquine. References The Canadian Hydroxychloroquine Study Group: N. Engl. J. Med., 324, 150 (1991).Fórmula:C18H26ClN3OCor e Forma:NeatPeso molecular:335.87Dehydrocorydaline chloride
CAS:Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.Fórmula:C22H24ClNO4Pureza:99.53%Cor e Forma:SolidPeso molecular:401.88Ref: TM-T10990
1mg58,00€5mg111,00€10mg160,00€25mg264,00€50mg396,00€100mg563,00€1mL*10mM (DMSO)124,00€Tioxazafen
CAS:Tioxazafen is a disubstituted oxadiazole, and is a broad-spectrum seed treatment nematicide.Fórmula:C12H8N2OSPureza:99.66%Cor e Forma:N9 5/90 0% R White SolidPeso molecular:228.27Ref: TM-T13928
5mg50,00€10mg74,00€25mg135,00€50mg197,00€100mg298,00€200mg420,00€1mL*10mM (DMSO)50,00€lufenuron
CAS:Lufenuron (Fluphenacur) is a chitin-synthesis inhibitor.Fórmula:C17H8Cl2F8N2O3Pureza:99.87%Cor e Forma:CoaPeso molecular:511.15Clofazimine
CAS:Fórmula:C27H22Cl2N4Pureza:>98.0%(T)(HPLC)Cor e Forma:Yellow to Amber to Dark red powder to crystalPeso molecular:473.40DihydroarteMisinic acid
CAS:DihydroarteMisinic acid (Dihydro-Artmisinic Acid) is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinalFórmula:C15H24O2Pureza:99.06% - 99.17%Cor e Forma:SolidPeso molecular:236.35GSK3186899
CAS:GSK3186899 is an inhibitor of Cdc2-related kinase 12 with an EC50 of 1.4 μM for L. donovani.Fórmula:C19H28F3N7O3SPureza:98.35% - 99.45%Cor e Forma:SolidPeso molecular:491.53Antileishmanial agent-17
CAS:Antileishmanial agent-17, a coumarin hybrid, exhibits potent antileishmanial activity (IC50 <0.78 μM) while proving non-toxic to normal VERO cells.Fórmula:C27H37N5O5Pureza:98%Cor e Forma:SolidPeso molecular:511.61Hexyl gallate
CAS:Hexyl gallate (Gallic acid hexyl ester), an alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum (IC50: 0.Fórmula:C13H18O5Pureza:99.81%Cor e Forma:SolidPeso molecular:254.28Benznidazol
CAS:Benznidazol (Benznidazole)e has an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulatingFórmula:C12H12N4O3Pureza:100% - 99.53%Cor e Forma:SolidPeso molecular:260.25Acetylspiramycin
CAS:Acetylspiramycin (Spiramycin B) targets 50S ribosome to inhibit protein synthesis.Fórmula:C45H76N2O15Pureza:≥98%Cor e Forma:White PowderPeso molecular:885.09Bruceine A
CAS:Bruceine A, a quassinoid from Brucea javanica fruit, may treat canine babesiosis.Fórmula:C26H34O11Pureza:99.13% - 99.85%Cor e Forma:SolidPeso molecular:522.54Ref: TM-T2S2046
1mg56,00€5mg119,00€10mg169,00€25mg283,00€50mg435,00€100mg640,00€1mL*10mM (DMSO)136,00€Nifuratel
CAS:Fórmula:C10H11N3O5SPureza:>98.0%(HPLC)Cor e Forma:White to Yellow to Green powder to crystalPeso molecular:285.27Clindamycin phosphate
CAS:Clindamycin phosphate: a broad-spectrum chlorinated antibiotic, modified from lincomycin, used topically.Fórmula:C18H34ClN2O8PSPureza:98.15%Cor e Forma:White SolidPeso molecular:504.96Antiproliferative agent-56
Antiproliferative agent-56 (Compound 31) is an antimalarial agent that inhibits the Pf3D7 strain of the malaria parasite Plasmodium falciparum with an IC50 of >12.5 (48h) and 0.03 μM (98h), displaying slow-acting characteristics.Cor e Forma:Odour SolidHYPOCRELLIN B
CAS:HYPOCRELLIN B, from Hypocrella bambusae, breaks DNA, triggers apoptosis in ovarian cells, and stops Staphylococcus growth via ROS.Fórmula:C30H24O9Pureza:98% - 98.87%Cor e Forma:SolidPeso molecular:528.51Spiramycin
CAS:Spiramycin, a Streptomyces-made macrolide antibiotic, targets gram-positive pathogens, N. gonorrhoeae, staph, and Toxoplasma gondii.Fórmula:C43H74N2O14Pureza:90.59% - 97.92%Cor e Forma:SolidPeso molecular:843.07Fmoc-N-Me-Phe-OH
CAS:Fmoc-N-Me-Phe-OH (Fmoc-N-methyl-L-phenylalanine) is a Malaria Parasite inhibitor.Fórmula:C25H23NO4Pureza:≥95%Cor e Forma:White PowderPeso molecular:401.45(3R-cis)-Dihydro-3-hydroxy-4-(phenylmethoxy)-2(3H)-furanone
CAS:Produto ControladoFórmula:C11H12O4Cor e Forma:NeatPeso molecular:208.215-O-Demethyl-28-Oxo-Avermectin A1A
CAS:Applications 5-O-Demethyl-28-oxo-Avermectin A1a is a derivatie of Ivermectin (I940800), which is a semi-synthetic derivative of Abamectin. An invitro inhibitor of SARS-CoV-2/ Covid-19. References Chabala, J.C., et al.: J. Med. Chem., 23, 1134 (1980); Campbell, W.C., et al.: Science, 221, 823 (1983); Bennett, J.L., et al.: Parasitol. Today, 4, 226 (1988); Plaisier, A.P., et al.: J. Infect. Dis., 172, 204 (1995);; Caly, L., et al.: Antivir. Res., 178Fórmula:C48H70O15Cor e Forma:NeatPeso molecular:887.06Anti-inflammatory agent 40
Anti-inflammatory agent 40 is a promising, orally-active compound with anti-malarial and anti-inflammatory properties.Fórmula:C30H24Cl2N2O4Pureza:98%Cor e Forma:SolidPeso molecular:547.43Pentamidine Isethionate
CAS:Fórmula:C19H24N4O2·2C2H6O4SPureza:>95.0%(HPLC)(qNMR)Cor e Forma:White to Light yellow powder to crystalPeso molecular:592.68Epimagnolin A
CAS:Epimagnolin A is a lignan obtained from the flower buds of Magnolia fargesii, which is traditionally used in Asian medicine for treating headache and nasalFórmula:C23H28O7Pureza:99.82% - ≥98%Cor e Forma:SolidPeso molecular:416.46Ref: TM-TN1610
1mg111,00€2mg166,00€5mg283,00€10mg419,00€25mg682,00€50mg939,00€100mg1.264,00€1mL*10mM (DMSO)320,00€N-Desethyl amodiaquine
CAS:N-Desethyl amodiaquine is an antiparasitic agent and the major bioactive amodiaquine metabolite.Fórmula:C18H18ClN3OPureza:98%Cor e Forma:SolidPeso molecular:327.81Alkaline tryptase-IN-1
Alkaline tryptase-IN-1 (compound H-13) is an insecticide that targets alkaline trypsin-like enzymes. It has lethal concentration (LC50) values of 8.72, 13.77, 14.17, 12.96, and 12.35 μg/mL against Schizaphis graminum, Sitobion avenae, Brevicoryne brassicae, Aphis gossypii, Aphis spiraecola, and Myzus persicae, respectively.Fórmula:C29H33BrN2O2SCor e Forma:SolidPeso molecular:553.55Imidocarb Dipropionate
CAS:Fórmula:C19H20N6O·2C3H6O2Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:496.57Diethylcarbamazine Citrate
CAS:Fórmula:C10H21N3O·C6H8O7Pureza:>98.0%(T)Cor e Forma:White to Almost white powder to crystalPeso molecular:391.42Deschloro Atovaquone
CAS:Produto ControladoApplications Naphthoquinone antimalarials. Atovaquone derivative.Fórmula:C22H20O3Cor e Forma:NeatPeso molecular:332.39Niclosamide
CAS:Niclosamide (Niclocide)(BAY2353) is used to treat most tapeworm infections by inhibiting DNA replication.Fórmula:C13H8Cl2N2O4Pureza:96.83% - 98.9%Cor e Forma:Pale Yellow Crystals SolidPeso molecular:327.12Artemether
CAS:Artemether (CGP 56696) is an antimalarial agent used to treat acute uncomplicated malaria.Fórmula:C16H26O5Pureza:99.87% - 99.93%Cor e Forma:SolidPeso molecular:298.37LUPENONE
CAS:Lupenone is a natural product isolated from Rhizoma Musae and has good anti-diabetic activity,and has anti-inflammatory activity.lupenone were potent PTP1BFórmula:C30H48OPureza:98% - 99.92%Cor e Forma:SolidPeso molecular:424.7Lumefantrine
CAS:Lumefantrine is an antimalarial compound with action on erythrocytic stages of Plasmodium falciparum by inhibiting β-hematin formation and is used for treating malaria in combination with artemether.Fórmula:C30H32Cl3NOPureza:Min. 95%Cor e Forma:PowderPeso molecular:528.94 g/molAmprolium
CAS:Amprolium is a veterinary coccidiostat that interferes with THIAMINE metabolism.Fórmula:C14H19N4·ClPureza:98%Cor e Forma:SolidPeso molecular:278.79PK 11195
CAS:PK 11195 binds translocator protein; anti-Leishmania with IC50s: L. amazonensis 14.2 μM, L. major 8.2 μM, L. braziliensis 3.5 μM.Fórmula:C21H21ClN2OPureza:99.05%Cor e Forma:SolidPeso molecular:352.86ML251
CAS:ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.Fórmula:C17H13Cl2N3O4SPureza:99.87%Cor e Forma:SolidPeso molecular:426.27Ref: TM-T64320
1mg133,00€5mg274,00€10mg432,00€25mg715,00€50mg1.008,00€100mg1.359,00€500mg2.717,00€1mL*10mM (DMSO)301,00€AWZ1066S
CAS:AWZ1066S is a highly specific anti-Wolbachia drug candidate for the short-course treatment of filariasis (EC50: 2.5 nM in cell assay).Fórmula:C19H19F3N6OPureza:98.32%Cor e Forma:SolidPeso molecular:404.39Ref: TM-T10423
1mg44,00€5mg93,00€10mg153,00€25mg235,00€50mg344,00€100mg512,00€200mg728,00€1mL*10mM (DMSO)93,00€
