Moduladores GABA
Os moduladores de GABA são compostos que influenciam a função dos receptores de GABA (ácido gama-aminobutírico), os principais receptores inibitórios de neurotransmissores no sistema nervoso central. Estes moduladores podem aumentar ou inibir a atividade GABAérgica, afetando a excitabilidade neuronal e a transmissão sináptica. Os moduladores de GABA são cruciais no tratamento e estudo de vários distúrbios neurológicos e psiquiátricos, incluindo ansiedade, epilepsia e insônia. Na CymitQuimica, oferecemos uma ampla gama de moduladores de GABA para apoiar sua pesquisa em neurociência, farmacologia e neuroterapêutica.
Produtos da "Moduladores GABA"
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6-Chloro-1-methyl-4-phenyl-2(1H)-quinazolinone
CAS:Produto ControladoImpurity Diazepam EP Impurity E Applications 6-Chloro-1-methyl-4-phenyl-2(1H)-quinazolinone (Diazepam EP Impurity E) is an impurity of Temazepam (T017200), which is a pharmacologically active metabolite. It is used as a sedative and hypnotic drug. References Sarteschi, P., et al.: Arzneim.-Forsch., 22, 93 (1972), Schwandt, H.J., et al.: Xenobiotica, 4, 733 (1974), Curry, S.H., et al.: Br. J. Pharmacol., 57, 427 (1976), Heel, R.C., et al.: Drugs, 21, 321 (1981)Fórmula:C15H11ClN2OCor e Forma:Light YellowPeso molecular:270.71Zaleplon
CAS:Produto ControladoApplications Selective non-benzodiazepine GABAA receptor agonist. References Allen, D., et al.: Eur. J. Clin. Pharmacol., 45, 313 (1993), Beer, B., et al.: J. Clin. Pharmacol., 34, 335 (1994), Rosen, A.S., et al.: Biopharm. Drug Dispos., 20, 171 (1999), Elie, R., et al.: J. Clin. Psychiatry, 60, 536 (1999), Heydorn, W.E., et al.: Expert Opin. Invest. Drugs, 9, 841 (2000)Fórmula:C17H15N5OCor e Forma:Off-WhitePeso molecular:305.33Pentanoic Acid (Valeric Acid)
CAS:Produto ControladoFórmula:C5H10O2Cor e Forma:NeatPeso molecular:102.13Flunitrazepam
CAS:Produto ControladoApplications Flunitrazepam is used as an hypnotic. This is a controlled substance (depressant). References Sternbach, L.H., et al.: J. Med. Chem., 6, 261 (1963), Eidelberg, E., et al.: Neurology, 5, 223 (1965), Caplan, Y., et al.: J. Anal. Toxicol., 25, 396 (2001), Wood, M., et al.: Forensic Sci. Int., 150, 227 (2005),Fórmula:C16H12FN3O3Cor e Forma:Off-WhitePeso molecular:313.28(5RS)-5-Ethyl-2-imino-5-phenyldihydropyrimidine-4,6(1H,3H)-dione (2-Amino-5-ethyl-5-phenyl-4,6(1H,5H)-pyrimidinedione)
CAS:Produto ControladoFórmula:C12H13N3O2Cor e Forma:NeatPeso molecular:231.255-Phenyl-5-ethyl-2-thiobarbituric Acid
CAS:Produto ControladoFórmula:C12H12N2O2SCor e Forma:NeatPeso molecular:248.3Phenobarbital (1.0mg/mL in Methanol)
CAS:Produto ControladoFórmula:C12H12N2O3Cor e Forma:Single SolutionPeso molecular:232.24Chlordiazepoxide-d5 (100ug/ml in Methanol)
CAS:Produto ControladoFórmula:C162H5H9ClN3OCor e Forma:Single SolutionPeso molecular:304.792-Aminomethyl-7-chloro-2,3-dihydro-5-(2-fluorophenyl)-1H-1,4-benzodiazepine
CAS:Produto ControladoApplications An Intermediate for the synthesis of Midazolam. References Walser, A., J. Org. Chem., 43, 936 (1978).Fórmula:C16H15ClFN3Cor e Forma:NeatPeso molecular:303.76Alprazolam-d3
CAS:Produto ControladoApplications Controlled substance (depressant). Anxiolytic. References Sethy, V.H., et al.: Arch. Pharmacol., 301, 157 (1978), Fawcett, J.A., et al.: Pharmacotherapy, 2, 242 (1982),Fórmula:C17H10ClD3N4Cor e Forma:NeatPeso molecular:311.807-Amino Nitrazepam
CAS:Produto ControladoApplications A metabolite of Nitrazepam (N490140). References Randall, L.O., et al.: Biochem. Pharmacol., 8, 15 (1961),Fórmula:C15H13N3OCor e Forma:Light YellowPeso molecular:251.284-Boc-9-Methyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Pureza:97.0%Peso molecular:262.35299682617197-Fluoro-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Fórmula:C10H9FN2O2Pureza:97%Cor e Forma:SolidPeso molecular:208.18917-Amino Nitrazepam-d5
CAS:Produto ControladoApplications A labelled metabolite of Nitrazepam (N490140(M)), which is an anticonvulsant; hypnotic.Controlled substance (depressant). References Randall, L.O., et al.: Biochem. Pharmacol., 8, 15 (1961), Rieder, et al.: Arzneim.-Forsch., 23, 212 (1973), Kangas, L., Acta Pharmacol. Toxicol., 45, 16 (1979), Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 9, 487 (1980)Fórmula:C15H8D5N3OCor e Forma:Light Yellow SolidPeso molecular:256.31(2RS)-2-Ethyl-2-methylbutanedioic Acid
CAS:Produto ControladoFórmula:C7H12O4Cor e Forma:NeatPeso molecular:160.168Gabapentin-lactam 100 µg/mL in Acetonitrile
CAS:Fórmula:C9H15NOCor e Forma:Single SolutionPeso molecular:153.222,3,4,5-TETRAHYDRO-1H-BENZO[E][1,4]DIAZEPIN-8-YLAMINE 2HCL
CAS:Pureza:97.0%Peso molecular:236.139999389648447-Amino-4-Boc-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Pureza:97.0%Peso molecular:263.34100341796875Zolpidem
CAS:Produto ControladoApplications A selective non-benzodiazepine GABAA receptor agonist. Sedative, hypnotic. Controlled substance (depresssant). References Arbilla, S., et al.: Arch. Pharmacol., 330, 248 (1985), Cashman, J.N., et al.: Brit. J. Clin. Pharmacol., 21, 205 (1986)Fórmula:C19H21N3OCor e Forma:Off-WhitePeso molecular:307.391H-1,4-Benzodiazepine, 2,3,4,5-tetrahydro-
CAS:Fórmula:C9H12N2Pureza:95%Cor e Forma:SolidPeso molecular:148.2050Clozapine, 97%
CAS:Potent, selective muscarinic antagonist This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C18H19Cl4Pureza:97%Peso molecular:326.8310H-Thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(4-methyl-1-piperazinyl)-
CAS:Fórmula:C17H20N4SPureza:%Cor e Forma:SolidPeso molecular:312.4325Lamotrigine EP Impurity C
CAS:Produto ControladoFórmula:C9H7Cl2N5Cor e Forma:NeatPeso molecular:256.09Flumazenil
CAS:Produto ControladoApplications Flumazenil is an imidazodiazepine which selectively blocks the central effects of classic benzodiazepines. It is used as benzodiazepine antagonist. References Hunkeler, W., et al.: Nature, 290, 514 (1981), Pole, P., et al.: Arch. Pharmacol., 316, 317 (1981), Timm, U., et al.: Arzneim.-Forsch., 33, 358 (1983),Fórmula:C15H14FN3O3Cor e Forma:Off WhitePeso molecular:303.29Butobarbital
CAS:Produto ControladoApplications Butobarbital is a barbiturate derivative that is used as a hypnotic agent with sedative and anticonvulsant properties. Butobarbital is a Controlled Substance. References Sitsen, J.M.A. et al.: Pharmac. Week., 109, 1 (1974); Adams, R.G.: Psychopharmacologia, 40, 185 (1974);Fórmula:C10H16N2O3Cor e Forma:White SolidPeso molecular:212.255-Ethylbarbituric Acid
CAS:Produto ControladoApplications 5-Ethylbarbituric Acid is an non-nucleoside inhibitors of HIV-1 reverse transcriptase. References Mitchell, M. L., et al.: Bioorg. Med. Chem. Lett., 20, 1589 (2010); Al-Turkistani, A., et al.: Molecules., 16, 4764 (2011);Fórmula:C6H8N2O3Cor e Forma:NeatPeso molecular:156.144-Boc-9-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Pureza:97.0%Peso molecular:282.76998901367191,2,4,5-Tetrahydro-benzo[e][1,4]diazepin-3-one
CAS:Pureza:97.0%Cor e Forma:SolidPeso molecular:162.19200134277344Benzamide, N-[3-chloro-4-(5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-ylcarbonyl)phenyl]-5-fluoro-2-methyl-
CAS:Fórmula:C27H21ClFN3O2Pureza:99%Cor e Forma:SolidPeso molecular:473.92594-Boc-7-Methyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Pureza:97.0%Peso molecular:262.35299682617192H-1,4-Benzodiazepin-2-one, 3-amino-1,3-dihydro-5-phenyl-, (3S)-
CAS:Pureza:98%Peso molecular:251.2894,6(1H,5H)-Pyrimidinedione, dihydro-2-thioxo-
CAS:Fórmula:C4H4N2O2SPureza:97%Cor e Forma:SolidPeso molecular:144.1518Ref: IN-DA001PPK
Produto descontinuadoMidazolam-D4 Maleate 0.1 mg/ml in Methanol (as free base)
CAS:Produto ControladoFórmula:C182H4H9ClFN3·C4H4O4
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