Moduladores GABA
Os moduladores de GABA são compostos que influenciam a função dos receptores de GABA (ácido gama-aminobutírico), os principais receptores inibitórios de neurotransmissores no sistema nervoso central. Estes moduladores podem aumentar ou inibir a atividade GABAérgica, afetando a excitabilidade neuronal e a transmissão sináptica. Os moduladores de GABA são cruciais no tratamento e estudo de vários distúrbios neurológicos e psiquiátricos, incluindo ansiedade, epilepsia e insônia. Na CymitQuimica, oferecemos uma ampla gama de moduladores de GABA para apoiar sua pesquisa em neurociência, farmacologia e neuroterapêutica.
Produtos da "Moduladores GABA"
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8-Demethyl-6-hydroxy Zolazepam
CAS:Produto ControladoApplications N-Demethylated-8-hydroxylated metabolite of the anesthetic agent, Zolazepam (Z613500). References Baukema, J. et al.: Res. Comm. Chem. Pathol. Pharmacol., 10, 227 (1975);Fórmula:C14H13FN4O2Cor e Forma:NeatPeso molecular:288.283,4-Dihydro-1H-1,4-benzodiazepine-2,5-dione
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:176.1750030517578Midazolam-D4.maleate, 1mg/ml in Methanol (as free base)
CAS:Produto ControladoFórmula:C182H4H9ClFN3·C4H4O43-Hydroxy-prazepam-D5
CAS:Produto ControladoFórmula:C19H12D5ClN2O2Cor e Forma:NeatPeso molecular:345.84Bromazepam
CAS:Produto ControladoApplications Controlled substance (depressant). Anxiolytic. References Schwartz, M.A., et al.: J. Pharm. Sci., 62, 1776 (1973), Chalmers, P., et al.: Anesthesia, 39, 370 (1984), Hassan, M.M., et al.: Anal. Profiles Drug Subs., 16, 1 (1987),Fórmula:C14H10BrN3OCor e Forma:WhitePeso molecular:316.15Barbituric Acid
CAS:Impurity Fluorouracil EP Impurity A Applications Barbituric Acid (Fluorouracil EP Impurity A) is a parent compound of barbiturate drugs. Unsubstituted barbituric acid has no hypnotic properties. References Luo, Y., et al.: J. Med. Chem., 53, 3846 (2010), Tomasic, T., et al.: Eur. J. Med. Chem., 45, 1667 (2010), Gilbert, A., et al.: Bioorg. Med. Chem. Lett., 20, 636 (2010),Fórmula:C4H4N2O3Cor e Forma:NeatPeso molecular:128.097-Amino Nitrazepam (1mg/ml in Methanol)
CAS:Produto ControladoFórmula:C15H13N3OCor e Forma:Single SolutionPeso molecular:251.28Deschloro-Zopiclone
CAS:Produto ControladoApplications Deschloro-Zopiclone is a metabolite of Zopiclone (Z700500) which is a cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists. References Noble, S., et al.: Drugs, 55, 277 (1998), Musch, B., et al.: Int. J. Clin. Psychopharmacol., 5, 147 (1990),Fórmula:C17H18N6O3Cor e Forma:NeatPeso molecular:354.36Gabapentin 100 µg/mL in Acetonitrile:Methanol
CAS:Produto ControladoFórmula:C9H17NO2Cor e Forma:Single SolutionPeso molecular:171.24Pirenzepine dihydrochloride, 99%
CAS:A M1 muscarinic receptor antagonist This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C19H23Cl2N5O2Pureza:99%Cor e Forma:Crystals or powder or crystalline powder, White to pale yellowPeso molecular:424.331-Methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Fórmula:C10H10N2O2Pureza:95%Cor e Forma:SolidPeso molecular:190.1986Pentobarbital-d5
CAS:Produto ControladoApplications Pentobarbital-d5 is labelled Pentobarbital (P276000, sodium salt) which is a short-acting barbiturate. Typical applications for pentobarbital are sedative, hypnotic for short term, preanesthetic and control of convulsions in emergencies. References Schafer, E.W., et al.: Toxicol. Appl. Pharmacol., 21, 315 (1972), Woster, P.S., et al.: Clin. Pharm., 9, 762 (1990), Evans, A.T., et al.: J. Am. Vet. Med. Assoc., 203, 664 (1993),Fórmula:C112H5H13N2O3Cor e Forma:WhitePeso molecular:231.30(Carbamoylamino)(diphenyl)acetic Acid
CAS:Produto ControladoFórmula:C15H14N2O3Cor e Forma:NeatPeso molecular:270.289-Nitro-3,4-dihydro-1H-benzo[e][1,4]diazepin-5(2H)-one
CAS:Pureza:95.0%Peso molecular:207.188995361328125-(4-Methylphenyl)-5-phenylimidazolidine-2,4-dione
CAS:Produto ControladoFórmula:C16H14N2O2Cor e Forma:NeatPeso molecular:266.29SKF 81297C
CAS:Produto ControladoApplications SKF 81297C is a dopamine D1 agonist (1). References (1) Bergman, J., et. al.: J. Pharmacol. Exp. Ther., 273, 40 (1995)Fórmula:C16H17BrClNO2Cor e Forma:NeatPeso molecular:370.67Lorazepam (100 μg/mL in Acetonitrile)
CAS:Produto ControladoFórmula:C15H10Cl2N2O2Cor e Forma:Single SolutionPeso molecular:321.16(Z)-2-Propylpent-3-enoic Acid
CAS:Produto ControladoFórmula:C8H14O2Cor e Forma:NeatPeso molecular:142.196Allylisopropylacetylurea
CAS:Produto ControladoApplications Allylisopropylacetylurea is used in a novel approach to cytochrome P-450 induction, through barbiturate-like activity. References Ruettinger, R. et al.: Biochim. Biophys. Acta Gen. Subj. et al.: 801, 374 (1984);Fórmula:C9H16N2O2Cor e Forma:NeatPeso molecular:184.24Phenobarbital 1-Butyric Acid
CAS:Produto ControladoFórmula:C16H18N2O5Cor e Forma:NeatPeso molecular:318.32Triazolam N-Oxide
CAS:Produto ControladoApplications Triazolam N-Oxide is a derivative of Triazolam (T767380), a sedative. References Lomen, P., et al.: J. Int. Med. Res., 4, 55 (1976); Allens, G.S., et al.: J. Int. Med. Res., 6, 343 (1978); Pakes, G.E., et al.: Drugs, 22, 81 (1981)Fórmula:C17H12Cl2N4OCor e Forma:NeatPeso molecular:359.21
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