Sistema complementar
O sistema complemento é uma parte crucial da resposta imunológica, consistindo em uma série de pequenas proteínas que melhoram a capacidade dos anticorpos e das células fagocíticas de eliminar patógenos de um organismo. Essas proteínas trabalham juntas para opsonizar patógenos, induzir respostas inflamatórias e lisar diretamente as membranas dos patógenos, desempenhando um papel vital na imunidade inata e na função imunológica geral. Na CymitQuimica, fornecemos proteínas de alta qualidade do sistema complemento para apoiar seus estudos imunológicos e pesquisas clínicas.
Produtos da "Sistema complementar"
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C1s Protein, Human, Recombinant (His)
Complement is an integral component of the adaptive and innate immune systems and represents one of the major effector systems for the immune responses.Cor e Forma:Lyophilized PowderPeso molecular:76.3 kDa (predicted); 82.06 kDa, 56.59 kDa and 33.36 kDa (reducing condition, due to glycosylation)C1QA Protein, Mouse, Recombinant (His)
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system.Pureza:90% - 92%Cor e Forma:Lyophilized PowderPeso molecular:25.6 kDa (predicted)Complement C5 Protein, Human, Recombinant (His & FLAG)
Complement C5 Protein, Human, Recombinant (His & FLAG) is expressed in HEK293 mammalian cells with His and Flag tag.Pureza:96.1%Cor e Forma:Lyophilized PowderPeso molecular:188.8 kDa (predicted)(Z)-Leukadherin-1
CAS:(Z)-Leukadherin-1 (ADH-503 free base) is an allosteric agonist of CD11b.Fórmula:C22H15NO4S2Pureza:99.23%Cor e Forma:SolidPeso molecular:421.49Complement C8a Protein, Human, Recombinant (His)
Complement C8a Protein, Human, Recombinant (His) is expressed in E. coli.Cor e Forma:Lyophilized PowderPeso molecular:65.8 kDa (predicted)C1QL3 Protein, Mouse, Recombinant (His & Myc)
May regulate the number of excitatory synapses that are formed on hippocampus neurons.Cor e Forma:Lyophilized PowderPeso molecular:28.6 kDa (predicted)Complement C2 Protein, Human, Recombinant (His)
Complement C2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Pureza:98.6%Cor e Forma:Lyophilized PowderPeso molecular:82.5 kDa (predicted)Eculizumab
CAS:Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5Pureza:98.20%Cor e Forma:LiquidPeso molecular:148 kDaComplement C5 Protein, Cynomolgus, Recombinant
Complement C5 Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells.Cor e Forma:Lyophilized PowderPeso molecular:8.41 kDa (predicted); 12.42 kDa (reducing conditions)C1QA Protein, Human, Recombinant (GST)
C1QA Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 50.58 kDa and the accession number is P02745.Cor e Forma:LiquidPeso molecular:50.58 kDa (predicted)Complement C5-IN-1
CAS:Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).Fórmula:C24H32N2O6Pureza:99.2%Cor e Forma:SolidPeso molecular:444.52Ref: TM-T10863
1mg92,00€5mg182,00€10mg264,00€25mg406,00€50mg540,00€100mg735,00€200mg938,00€1mL*10mM (DMSO)200,00€Zilucoplan (PEG2)
Zilucoplan(PEG2) is a derivative of Zilucoplan where the linker component has been substituted with PEG2 instead of PEG24. This compound acts as an effective inhibitor of complement component 5 (C5).Fórmula:C128H190N24O33Cor e Forma:SolidPeso molecular:2593.02JR14a
CAS:JR14a (5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride) is a potent antagonist of human complement C3a receptor.Fórmula:C25H26Cl2N4O3SPureza:99.76%Cor e Forma:SolidPeso molecular:533.47Ref: TM-T9316
1mg92,00€5mg188,00€10mg298,00€25mg507,00€50mg730,00€100mg1.026,00€1mL*10mM (DMSO)215,00€Complement C3 Protein, Human, Recombinant (His)
Complement C3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Pureza:SDS-PAGE: 93.4%; SEC-HPLC: 94.7% - SDS-PAGE: 95.5%; SEC-HPLC: 92.6%Cor e Forma:Lyophilized PowderPeso molecular:186.43 kDa (predicted)Properdin Protein, Mouse, Recombinant (His)
A positive regulator of the alternate pathway of complement.Cor e Forma:Lyophilized PowderPeso molecular:51.9 kDa (predicted)Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.Cor e Forma:Lyophilized PowderPeso molecular:52.2 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.Dexamethasone
CAS:Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.Fórmula:C22H29FO5Pureza:98% - 99.91%Cor e Forma:Crystals From Ether (Ntp 1992)Peso molecular:392.46MBL1 Protein, Rat, Recombinant (hFc)
MBL1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Cor e Forma:Lyophilized PowderPeso molecular:50.5 kDa (predicted); 56 kDa (reducing conditions)Complement C3 Protein, Bovine, Recombinant (His & SUMO)
Complement C3 Protein, Bovine, Recombinant (His & SUMO) is expressed in E.Cor e Forma:Lyophilized PowderPeso molecular:39.5 kDa (predicted)
