
Esteroides e Derivados
Os esteroides são compostos orgânicos que possuem uma estrutura de quatro anéis fundidos, conhecida como núcleo esteroide. Esse núcleo pode estar ligado a vários grupos funcionais que modificam suas propriedades e funções biológicas. Os esteroides desempenham um papel fundamental na regulação dos processos metabólicos e hormonais. São utilizados na medicina para tratar distúrbios inflamatórios, doenças autoimunes e desequilíbrios hormonais. Além disso, alguns derivados de esteroides possuem potentes propriedades anti-inflamatórias, como os corticosteroides. Em terapias específicas, são utilizados para reduzir a inflamação e controlar a dor em diversas doenças.
Na CymitQuimica, oferecemos uma variedade de esteroides e seus derivados para pesquisa e desenvolvimento farmacêutico.
Produtos da "Esteroides e Derivados"
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5-β-Finasteride
CAS:Fórmula:C23H36N2O2Cor e Forma:Off-White To Pale Yellow SolidPeso molecular:372.55Dutasteride impurity F
CAS:Dutasteride impurity D is a natural impurity found in dutasteride and has been reported to be an analytical marker for dutasteride. It is also used as an impurity standard, HPLC standard, and custom synthesis for drug development. Metabolism studies have shown that the major route of elimination for Dutasteride impurity D is through glucuronidation with minor amounts being excreted in urine unchanged.Fórmula:C27H31ClF6N2O2Pureza:Min. 95 Area-%Peso molecular:564.99 g/molBetamethasone 21-Acetate
CAS:Fórmula:C24H31FO6Cor e Forma:White To Off-White SolidPeso molecular:434.50Difluprednate Impurity 15
CAS:Fórmula:C21H24F2O4Cor e Forma:White To Off-White SolidPeso molecular:378.42(3R,5S)-Fluvastatin
CAS:(3R,5S)-Fluvastatin, a synthetic HMG-CoA reductase inhibitor (IC50: 8 nM), activates Nrf2 for antioxidant defense.Fórmula:C24H26FNO4Cor e Forma:SolidPeso molecular:411.479α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one
CAS:Impurity Clobetasol Propionate EP Impurity J Applications 9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one (Clobetasol Propionate EP Impurity J) is an impurity in the synthesis of Clobetasol 17-Propionate (C583500), a topical corticosteroid. Glucocorticoid; anti-inflammatory. References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986),Fórmula:C25H30ClFO4Cor e Forma:NeatPeso molecular:448.9517-α-Ethynyl Estradiol-17-Sulfate Triethylamine Salt
CAS:Fórmula:C20H24O5S·C6H15NCor e Forma:Off-White SolidPeso molecular:376.47 101.19Prednisolone Impurity 1
CAS:Fórmula:C21H26O5Cor e Forma:White To Off-White SolidPeso molecular:358.43Fluprednisolone
CAS:Fluprednisolone (NSC-47439) is a synthetic glucocorticoid that has anti-inflammatory properties.Fórmula:C21H27FO5Pureza:98.44%Cor e Forma:White To Off-White Powder SolidPeso molecular:378.43Ref: TM-T9047
1mg49,00€2mg67,00€5mg95,00€10mg137,00€25mg226,00€50mg338,00€100mg500,00€500mg1.074,00€1mL*10mM (DMSO)111,00€Desonide 21-Aldehyde Hydrate
CAS:Fórmula:C24H32O7C24H30O6Cor e Forma:Pale Yellow SolidPeso molecular:432.52 414.50Estradiol-d4 (Estradiol Valerate EP Impurity A-d4, Estriol EP Impurity D-d4, Ethinylestradiol EP Impurity D-d4)
CAS:Fórmula:C18H20D4O2Cor e Forma:White To Off-White SolidPeso molecular:276.41Androsterone
CAS:Produto ControladoApplications A steroid hormone with weak androgenic activity. It is metabolized from Testosterone (T155000) in the liver and is used in doping analysis to detect testosterone misuse. Controlled Substance.This compound is a contaminant of emerging concern (CECs). References Park, J., et al.: J. Anal. Toxicol., 14, 66 (1990), Palonek, E., et al.: J. Steroid Mol. Biol., 55, 121 (1995), Aguilera, R., et al.: Clin. Chem. 47, 292 (2001), Flenker, U., et al.: Steroids, 73, 408 (2008),Fórmula:C19H30O2Cor e Forma:White To Off-WhitePeso molecular:290.44Mometasone Furoate EP Impurity Q
CAS:Fórmula:C22H27ClO4Cor e Forma:White To Off-White SolidPeso molecular:390.9011β,16α,17α,21-Tetrahydroxypregna-1,4-diene-3,20-dione-d3
Produto ControladoApplications A labelled metabolite of Budesonide (B689490), an antiinflammatory agent. References Cserhati, T., et al.: J. Pharm. Biomed. Anal., 22, 25 (2000), Dilger, K., et al.: J. Clin. Pharmacol., 47, 1532 (2007), Buchwald, P., et al.: Steroids, 73, 193 (2008),Fórmula:C21H25D3O6Cor e Forma:NeatPeso molecular:379.46Fluvastatin EP Impurity F Sodium Salt
CAS:Fórmula:C24H23FNO3·NaCor e Forma:Yellow SolidPeso molecular:392.45 22.99Ref: 4Z-D-753
5mgA consultar10mgA consultar20mg2.703,00€25mgA consultar50mgA consultar100mgA consultarNorethindrone Impurity 33 (Norethisterone 3-Hexenoate)
Fórmula:C26H34O3Cor e Forma:White To Off-White SolidPeso molecular:394.56Ref: 4Z-C-2792
Produto descontinuadoRef: 4Z-D-732
Produto descontinuado6-Hydroxy Dexamethasone (Mixture of Diastereomers)
CAS:Fórmula:C22H29FO6Cor e Forma:White To Off-White SolidPeso molecular:408.47Norethindrone Impurity 36
CAS:Fórmula:C20H28O2Cor e Forma:White To Off-White SolidPeso molecular:300.4417-α-Ethynyl Estradiol-3,17-Disulfate
CAS:Fórmula:C20H24O8S2Cor e Forma:White To Off-White SolidPeso molecular:456.52L-Ascorbic acid 2-phosphate trisodium
CAS:L-Ascorbic acid 2-phosphate trisodium (Sodium ascorbyl phosphate) is a long-acting vitamin C derivative that stimulates collagen expression and formation.Fórmula:C6H6Na3O9PPureza:100% - 99.5%Cor e Forma:SolidPeso molecular:322.05Progesterone Impurity 27 and Progesterone EP Impurity G
Fórmula:C27H38O2Cor e Forma:White To Off-White SolidPeso molecular:394.60Lasofoxifene Tartrate
CAS:Lasofoxifene Tartrate (CP-336156) is a third-generation, non-steroidal selective estrogen receptor modulator.Fórmula:C32H37NO8Pureza:98.53%Cor e Forma:SolidPeso molecular:563.64γ-Tocopherol
CAS:(+)-γ-Tocopherol ((+)-γ-Tocopherol) is one of the naturally occurring forms of Vitamin E. It is the most abundant Tocopherol in soybean and corn oils.Fórmula:C28H48O2Pureza:99.31% - 99.39%Cor e Forma:Clear Viscous Pale Yellow Oil Which Oxidises And Darkens On Exposure To Air Or LightPeso molecular:416.68Estradiol-3-Glucuronide
CAS:Fórmula:C24H32O8Cor e Forma:White To Off-White SolidPeso molecular:448.5116α-Methyl-11-oxo Prednisolone
CAS:Produto ControladoApplications A 16α-substituted Prednisolone as potent topical antiinflammatory agent. References Lutsky, B.N., et al.: Arzneim.-Forsch., 29, 1662 (1979),Fórmula:C22H28O5Cor e Forma:White SolidPeso molecular:372.45Abiraterone Epoxide Impurity 20 (Mixture of α and β-Epoxy Abiraterone Acetate)
CAS:Fórmula:C26H33NO3Cor e Forma:White To Off-White SolidPeso molecular:407.55Anecortave Acetate
CAS:Anecortave Acetate (NSC-24345), an angiostatic steroid, is used for proteomics research.Fórmula:C23H30O5Pureza:99.88%Cor e Forma:SolidPeso molecular:386.48Dexamethasone Impurity 25 Trisodium Salt
CAS:Fórmula:C22H29FO11PS·3NaCor e Forma:White To Off-White SolidPeso molecular:551.52 3*22.99Flumethasone 21-acetate
CAS:Flumethasone 21-acetate is an anti-inflammatory corticosteroid.Fórmula:C24H30F2O6Cor e Forma:SolidPeso molecular:452.49Methylprednisolone Impurity 5
Fórmula:C22H28O4Cor e Forma:White To Off-White SolidPeso molecular:356.46Ref: 4Z-C-27117
Produto descontinuadoBudesonide EP Impurity H (Mixture of Diastereomers)
CAS:Fórmula:C25H32O5Cor e Forma:Pale Yellow SolidPeso molecular:412.53Estradiol (cypionate)
CAS:Estradiol cypionate (Depofemin), the 17 β-cyclopentylpropinate ester of estradiol, inhibits ET-1 synthesis via estrogen receptor.Fórmula:C26H36O3Pureza:100% - 99.53%Cor e Forma:White Or Off-White Crystalline PowderPeso molecular:396.56Fluocinolone Acetonide EP Impurity A (Fluocinolone Acetonide-21-Carboxylic Acid)
CAS:Fórmula:C24H28F2O7Cor e Forma:White To Off-White SolidPeso molecular:466.48Dienogest EP Impurity F
CAS:Fórmula:C20H27NO2Cor e Forma:White To Off-White SolidPeso molecular:313.44Medroxyprogesterone Acetate EP Impurity I
Fórmula:C22H32O3Cor e Forma:White To Off-White SolidPeso molecular:344.50(3α,5β,20S)-17,20-Dihydroxypregnan-3-yl β-D-Glucopyranosiduronic Acid
Fórmula:C27H44O9Peso molecular:512.65Digoxin EP Impurity H (Lanatoside C)
CAS:Fórmula:C49H76O20Cor e Forma:White To Off-White SolidPeso molecular:985.13Limaprost
CAS:Limaprost (17α,20-dimethyl-δ2-PGE1) is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency.It is aFórmula:C22H36O5Pureza:99.61% - 99.89%Cor e Forma:SolidPeso molecular:380.525,6-trans-Travoprost
CAS:Fórmula:C26H35F3O6Cor e Forma:Colorless Liquid To Semi-SolidPeso molecular:500.56Estrone-d4-3-glucuronide (Estrone-d4 β-D-Glucuronide Sodium Salt)
Fórmula:C24H26O8D4Peso molecular:450.53Methylprednisolone Impurity 10
CAS:Fórmula:C22H30O5Cor e Forma:White To Off-White SolidPeso molecular:374.48(3a,5ß,17ß)-4-Chloro-3-Hydroxy-17-Methyl-18-Norandrost-13-Ene-17-Methanol
CAS:Fórmula:C20H31ClO2Peso molecular:338.92Desoximetasone
CAS:Desoximetasone (Topicort) is a topical corticosteroid for treating skin conditions like rashes.Fórmula:C22H29FO4Pureza:99.06% - 99.89%Cor e Forma:SolidPeso molecular:376.46Prednisolone Impurity (9-Hydroxy Prednisolone)
Fórmula:C21H28O5Cor e Forma:White To Off-White SolidPeso molecular:360.45Hexestrol diphosphate tetrasodium
CAS:Hexestrol diphosphate tetrasodium: synthetic ER agonist, may cause cancer, inhibits microtubule assembly, leads to mitotic arrest and DNA adducts.Fórmula:C18H24O8P2·xNaCor e Forma:SolidPeso molecular:518.26Loteprednol Etabonate-d5
CAS:Fórmula:C24H26D5ClO7Cor e Forma:White To Off-White SolidPeso molecular:471.99Cortisol Impurity 1 ((E)-17-Deoxyaldehyde Derivative)
CAS:Fórmula:C21H28O4Cor e Forma:White To Off-White SolidPeso molecular:344.45Ref: 4Z-C-2737
Produto descontinuadoAtorvastatin lactam sodium salt impurity
CAS:Atorvastatin is a drug used for the treatment of hypercholesterolemia and cardiovascular diseases. Atorvastatin lactam, which is an impurity formed during the synthesis of atorvastatin, has been shown to inhibit cholesterol biosynthesis in a rat model. The in vivo metabolism of atorvastatin lactam was studied by HPLC-MS/MS and was found to be identical to that of the parent molecule. This impurity may be useful as a research and development or custom synthesis product, or as an impurity standard for HPLC analysis.Fórmula:C33H34FN2NaO6Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:596.62 g/molChenodeoxycholic acid
CAS:Pureza:95.0%Cor e Forma:Solid, Crystalline Powder or Needles or PowderPeso molecular:392.5799865722656Ethinylestradiol EP Impurity E (6-α-Hydroxy Ethinylestradiol)
CAS:Fórmula:C20H24O3Peso molecular:312.41Atorvastatin tert-butyl ester
CAS:Atorvastatin tert-butyl ester is an acid that is used to treat high cholesterol. It is a synthetic statin that inhibits the enzyme HMG-CoA reductase and blocks the production of cholesterol in the liver. This drug is administered orally, as a tablet or capsule, or in liquid form as a suspension. The drug has a bitter taste and evaporation may occur if it comes into contact with skin or clothes. Atorvastatin tert-butyl ester may be found in polymorphic forms (including dihydropyridine, dihydrospirocyclopentane, and dihydrobenzoquinoline). These forms are inactive, but can be activated by exposure to light or heat. These reactions produce an acidic compound that can react with other compounds to form new compounds.Fórmula:C37H43FN2O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:614.75 g/molBetamethasone 17-Propionate-d5
CAS:Produto ControladoFórmula:C25H28D5FO6Cor e Forma:NeatPeso molecular:453.564-Methyl Estradiol Enanthate Impurity
Fórmula:C26H38O3Cor e Forma:White To Off-White SolidPeso molecular:398.59Fluvastatin-d6 Sodium Salt
CAS:Fórmula:C24H19D6FNO4·NaCor e Forma:Off-White SolidPeso molecular:416.50 22.99Triamcinolone
CAS:Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.Fórmula:C21H27FO6Pureza:98.59% - 99.60%Cor e Forma:SolidPeso molecular:394.435α-Androstanedione
CAS:Produto ControladoApplications 5α-Androstanedione is a metabolite of Androstendione (A637550). 5α-Androstanedione is an important intermediate in the conversion of Androstenedione to Androstanolone (A637540). References Milewich, L., et al.: J. Steroid Chem., 16, 81 (1982); Stanczyk, F. Z., et al.: J. Steroid Biochem. Mol. Biol., 37, 129 (990);Fórmula:C19H28O2Cor e Forma:NeatPeso molecular:288.42Atorvastatin Impurity 87
CAS:Fórmula:C14H23NO4Cor e Forma:White To Off-White SolidPeso molecular:269.34Fluocortolone Impurity 1
CAS:Fórmula:C27H37FO5Cor e Forma:White To Off-White SolidPeso molecular:460.59(3S,5R)-Fluvastatin Sodium Salt
CAS:Fórmula:C24H25FNO4·NaCor e Forma:White To Off-White SolidPeso molecular:410.47 22.99Halobetasol Propionate Impurity 7
Fórmula:C25H31ClF2O5Cor e Forma:White To Off-White SolidPeso molecular:484.96Betamethasone acetate
CAS:Betamethasone acetate, the 21-acetate ester of betamethasone, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester.Fórmula:C24H31FO6Cor e Forma:SolidPeso molecular:434.5Estrone (Estradiol Hemihydrate EP Impurity A)
CAS:Fórmula:C18H22O2Cor e Forma:White To Off-White SolidPeso molecular:270.37Ref: 4Z-C-27118
Produto descontinuadoAndrost-4-ene-3,6,17-trione
CAS:Produto ControladoApplications An aromatase inhibitor. References Aello, A., et al.: J. Nat. Prod., 54, 281 (1991), Salaja, B.A., et al.: Steroids, 59, 330 (1994), Hunter, A.C., et al.: J. Steroid Biochem. Mol. Biol., 87, 301 (2003),Fórmula:C19H24O3Cor e Forma:NeatPeso molecular:300.39(3S,5S)-Atorvastatin sodium salt
CAS:Atorvastatin is a statin drug that inhibits the enzyme HMG-CoA reductase, which is responsible for cholesterol synthesis. Atorvastatin is used to lower LDL cholesterol and total cholesterol levels in the blood. It also lowers triglyceride levels and raises HDL cholesterol levels. Atorvastatin has been shown to inhibit fibrinogen production, reduce TNF-α production, and improve body mass index (BMI) in obese patients. This drug has been shown to be effective in reducing the size of atherosclerotic lesions by decreasing the amount of cholesteryl esters transferred from high-density lipoprotein (HDL) to low-density lipoprotein (LDL). It has also been shown to inhibit collagen production and stimulate muscle cell proliferation.Fórmula:C33H34FN2NaO5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:580.62 g/molRef: 4Z-C-275
Produto descontinuadoCholesterol Impurity 6 Sulfate Triethylamine Salt
Fórmula:C28H47O4S·C6H15NCor e Forma:White To Off-White SolidPeso molecular:480.75 101.19Ref: 4Z-C-27129
Produto descontinuadoBetamethasone 21-Mesylate (>90%)
CAS:Produto ControladoFórmula:C23H31FO7SPureza:>90%Cor e Forma:NeatPeso molecular:470.55Estra-1,3,5(10)-triene-3,16β,17β-triol (16-epi-Estriol)
CAS:Produto ControladoFórmula:C18H24O3Cor e Forma:NeatPeso molecular:288.38PF-02413873
CAS:PF-02413873 is a competitive antagonist of nonsteroidal progesterone receptor with a Ki of 2.6 nM.Fórmula:C18H21N3O3SPureza:100% - 99.90%Cor e Forma:SolidPeso molecular:359.44Ref: TM-T28362
1mg40,00€2mg50,00€5mg88,00€10mg126,00€25mg250,00€50mg400,00€100mg597,00€500mg1.283,00€1mL*10mM (DMSO)87,00€Ref: 4Z-D-416
Produto descontinuadoHydrocortisone EP Impurity C
CAS:Fórmula:C23H32O6Cor e Forma:White To Off-White SolidPeso molecular:404.51Ref: 4Z-C-2742
Produto descontinuadoFluocinolone Acetonide 21-Methoxy
CAS:Fórmula:C25H32F2O7Cor e Forma:White To Off-White SolidPeso molecular:482.52Medroxyprogesterone Acetate EP Impurity B (Medroxyprogesterone Acetate USP Related Compound B, Medroxyprogesterone)
CAS:Fórmula:C22H32O3Cor e Forma:White To Off-White SolidPeso molecular:344.5017α-Progesterone
CAS:Applications 17α-Progesterone is a testosterone precursror generated from cholesterol. Also used as a diagnostic agent in the identification and study of ovarian Leydig cell tumor disease. References Vesely, D. et al.: Proc. Natl. Acad. Sci. USA., 76, 3491 (1979); Arhan, E. et al.: J. Pediatric Endocrinol. Metab., 21, 181 (2008);Fórmula:C21H30O2Cor e Forma:NeatPeso molecular:314.46Ref: 4Z-C-2746
Produto descontinuado