Nucleosídeos e Nucleotídeos
Os nucleosídeos são compostos formados por uma base nitrogenada ligada a um açúcar (ribose ou desoxirribose). Quando um grupo fosfato é adicionado ao nucleosídeo, forma-se um nucleotídeo. Esses compostos são essenciais na biologia celular, pois os nucleotídeos são os blocos fundamentais do DNA e RNA, responsáveis pelo armazenamento e transmissão da informação genética. Os nucleosídeos têm aplicações no tratamento de doenças virais, atuando como inibidores da replicação viral. Os nucleotídeos, além do seu papel estrutural nos ácidos nucleicos, participam de processos energéticos, como a síntese de ATP.
Na CymitQuimica, oferecemos uma ampla gama de nucleosídeos e nucleotídeos essenciais para pesquisa em biologia molecular, virologia e farmacologia.
Produtos da "Nucleosídeos e Nucleotídeos"
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NADPH tetrasodium salt
CAS:NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety ofFórmula:C21H26N7Na4O17P3Pureza:100% - 99.65%Cor e Forma:SolidPeso molecular:833.35Azacitidine Impurity 13
CAS:Fórmula:C8H13N5O5Cor e Forma:White To Off-White SolidPeso molecular:259.22ent-Entecavir
CAS:Produto ControladoApplications ent-Entecavir is an enantiomeric impurity of the antiviral drug Entecavir (E558900). References Ruediger, E. et al.: Tetrahed. Lett., 45, 739 (2004): Bisacchi, G.S. et al.: Bioorg. Med. Chem. Lett., 7, 127 (1997);Fórmula:C12H15N5O3Cor e Forma:NeatPeso molecular:277.28Casein kinase 1δ-IN-9
CAS:Casein kinase 1δ-IN-9 is a Quinone reductase 2 inhibitor with IC50 of 0.6μM.Fórmula:C15H12ClN3Pureza:99.74%Cor e Forma:SolidPeso molecular:269.73Ref: TM-T64376
1mg96,00€5mg197,00€10mg295,00€25mg474,00€50mg638,00€100mg848,00€200mg1.121,00€1mL*10mM (DMSO)180,00€Entecavir (1S,3S,4S) diastereomer
CAS:Entecavir is a drug product that is custom synthesized to order. It has a purity of >98% and is made up of the 1S,3S,4S diastereomer. Entecavir is an antiviral drug that belongs to the nucleoside analog family and inhibits viral replication by inhibiting DNA polymerase α. The metabolism studies for entecavir have been completed and it was found that entecavir undergoes hydrolysis by esterases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Entecavir also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.Fórmula:C12H15N5O3Pureza:Min. 95%Peso molecular:277.28 g/molEIDD-2801
CAS:EIDD-2801 (Molnupiravir) is a prodrug for N 4-hydroxycytidine, effective against influenza and various coronaviruses.Fórmula:C13H19N3O7Pureza:100% - 99.70%Cor e Forma:SolidPeso molecular:329.31Ref: TM-T8309
1g657,00€5mg40,00€10mg60,00€25mg79,00€50mg119,00€100mg187,00€200mg350,00€500mg449,00€1mL*10mM (DMSO)66,00€Emtricitabine triphosphate tetrasodium salt
CAS:Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of the phosphorylated anabolite (-)-Emtricitabine triphosphate, an active nucleosideFórmula:C8H9FN3Na4O12P3SPureza:98%Cor e Forma:SolidPeso molecular:575.11rac-Melphalan EP Impurity B DiHCl
CAS:Fórmula:C13H18N2O3·2HClCor e Forma:Pale Purple SolidPeso molecular:250.30 2*36.462'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine
2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine is an analytical standard that is used in research and development of drugs. This compound has been designated as an impurity in a drug product. It has also been used as a reference standard for HPLC analysis. 2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine is a metabolite of the drug product. This compound is not found in nature and has been synthesized artificially.Fórmula:C9H12F2N2O6Pureza:Min. 95%Peso molecular:282.2 g/mol
