![4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indazole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FFT52004.webp&w=3840&q=75)
4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indazole
CAS:
Ref. 3D-FT52004
Informação sobre produto
Nome:4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indazole
Marca:Biosynth
Descrição:4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indazole is a phosphoinositide inhibitor that induces apoptosis in cancer cells. It targets the enzyme phosphatidylinositol 3-kinase (PI3K) and the downstream target of PI3K: phosphatidylinositol 3-phosphate (PI3P). The PI3P is a precursor for other lipids such as phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidylinositol 4-phosphate (PIP). These lipids are involved in the regulation of cell proliferation and apoptosis. This compound has a significant inhibitory effect on cancer cell lines and inhibits cancer growth in an animal model.
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Propriedades químicas
Peso molecular:244.1 g/mol
Fórmula:C13H17BN2O2
Pureza:Min. 95%
InChI:InChI=1S/C13H17BN2O2/c1-12(2)13(3,4)18-14(17-12)10-6-5-7-11-9(10)8-15-16-11/h5-8H,1-4H3,(H,15,16)
Chave InChI:InChIKey=YRPXZCWDXBNPBD-UHFFFAOYSA-N
SMILES:CC1(C)OB(c2cccc3[nH]ncc23)OC1(C)C