CAS 305-03-3: Chlorambucil
Formula:C14H19Cl2NO2
InChI:InChI=1S/C14H19Cl2NO2/c15-8-10-17(11-9-16)13-6-4-12(5-7-13)2-1-3-14(18)19/h4-7H,1-3,8-11H2,(H,18,19)
InChI key:InChIKey=JCKYGMPEJWAADB-UHFFFAOYSA-N
SMILES:N(CCCl)(CCCl)C1=CC=C(CCCC(O)=O)C=C1
Synonyms:- 4-(P-Bis(2-Chloroethyl)Aminophenyl)Butyric Acid
- 4-(P-Bis(Beta-Chloroethyl)Aminophenyl)Butyric Acid
- 4-(p-(N,N-Di-2-chloroethyl)aminophenyl)butyric acid
- 4-(p-N,N-Di-(beta-chloroethyl)aminophenyl)butyric acid
- 4-[4-[3-Chloro-1-(2-Chloroethyl)Propyl]Phenyl]Butanoic Acid
- 4-[Bis(2-Chloroethyl)Amino]Benzenebutanoic Acid
- 4-[Bis(2-chloroethyl)aminophenyl]butyric acid
- 4-[p-[Bis(2-chloroethyl)amino]phenyl]butyric acid
- 4-{4-[Bis(2-Chloroethyl)Amino]Phenyl}Butanoic Acid
- Ambochlorin
- Amboclorin
- See more synonyms
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Chlorambucil for system suitability CRS
CAS:Chlorambucil for system suitability CRSFormula:C14H19Cl2NO2Color and Shape:PowderMolecular weight:304.2122Chlorambucil with impurity G CRS
CAS:Chlorambucil with impurity G CRSFormula:C14H19Cl2NO2Color and Shape:PowderMolecular weight:304.2122CHLORAMBUCIL CRS
CAS:CHLORAMBUCIL CRSFormula:C14H19Cl2NO2Color and Shape:PowderMolecular weight:304.2122Chlorambucil
CAS:Chlorambucil (CB-1348) is an orally-active antineoplastic aromatic nitrogen mustard.Formula:C14H19Cl2NO2Purity:97.37% - 98.45%Color and Shape:Off-White Slightly Granular Powder Melting Point 65-69°CMolecular weight:304.21Chlorambucil
CAS:Formula:C14H19Cl2NO2Color and Shape:Pale Yellow To Off-White SolidMolecular weight:304.22Chlorambucil, EP grade
CAS:Formula:C14H19Cl2NO2Purity:≤ 0.1% (HPLC)Color and Shape:White or almost white crystalline powderMolecular weight:304.21Chlorambucil
CAS:ChlorambucilFormula:C14H19Cl2NO2Purity:99.4%Color and Shape:WhiteMolecular weight:303.07928Chlorambucil-d8
CAS:Controlled ProductFormula:C14D8H11Cl2NO2Color and Shape:NeatMolecular weight:312.262Chlorambucil
CAS:Formula:C14H19Cl2NO2Purity:>98.0%(GC)(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:304.214-[Bis(2-chloroethyl)aminophenyl]butyric acid
CAS:4-[Bis(2-chloroethyl)aminophenyl]butyric acid is a bicyclic heterocycle that has been shown to be toxic to human epidermal cells. It binds to the integrin receptor on the cell surface, and initiates ATP-dependent transport, which leads to an influx of chloride ions into the cell. This influx alters the intracellular pH in a way that inhibits protein synthesis. 4-[Bis(2-chloroethyl)aminophenyl]butyric acid also has significant cytotoxicity against cancer cells, pluripotent cells, and even healthy human serum. Indeed, this compound is so potent that it was used in toxicity studies for other drugs such as chlorambucil.Formula:C14H19Cl2NO2Purity:Min. 95%Color and Shape:White PowderMolecular weight:304.21 g/molRef: 3D-FB35471
Discontinued productChlorambucil
CAS:Aromatic amino-acids and their esters,other than those containing more than one kind of oxygen function for use as drugsFormula:C14H19Cl2NO2Color and Shape:White Off-White Granular Crystalline Powder NeedlesMolecular weight:303.07928Chlorambucil
CAS:Formula:C14H19Cl2NO2Purity:≥ 98.0% (anhydrous)Color and Shape:White to off-white crystalline powderMolecular weight:304.21Chlorambucil-d8
CAS:Formula:C14H11D8Cl2NO2Color and Shape:White To Off-White SolidMolecular weight:312.26Benzenebutanoic acid, 4-[bis(2-chloroethyl)amino]-
CAS:Formula:C14H19Cl2NO2Purity:98%Color and Shape:SolidMolecular weight:304.2122Chlorambucil
CAS:Controlled ProductApplications Chlorambucil is a alkylating agent that is used as an chemotherapy drug in the treatment of chronic lymphocytic leukemia. Chlorambucil is also used to treat non-Hodgkin's lymphoma (NHL) and Hodgkin's disease. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Cogia, A., et al.: Leuk. Lymph., 53, 1961 (2012); Tonino, S.H., et al.: Leuk. Lymph., 53, 1785 (2012); Smolej, L., et al.: Curr. Pharma. Design., 18, 3399 (2012);Formula:C14H19Cl2NO2Color and Shape:White To Light BeigeMolecular weight:304.21
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![Benzenebutanoic acid, 4-[bis(2-chloroethyl)amino]-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0030DZ.jpg&w=3840&q=75)
