CAS 67-97-0: Vitamin D3
Formula:C27H44O
InChI:InChI=1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1
InChI key:InChIKey=QYSXJUFSXHHAJI-YRZJJWOYSA-N
SMILES:C[C@@]12[C@](\C(=C\C=C\3/C(=C)CC[C@H](O)C3)\CCC1)(CC[C@@]2([C@@H](CCCC(C)C)C)[H])[H]
Synonyms:- (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-Dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylenecyclohexanol
- (3,beta., 5Z, 7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
- (3S,5Z,7E)-9,10-secocholesta-5,7,10-trien-3-ol
- (5Z,7E)-9,10-secocholesta-5,7,10-trien-3-ol
- 7-Dehydrocholesterol, irradiated
- 7-Dehydrocholestrol, activated
- 9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3-ol
- 9,10-Secocholesta-5,7,10(19)-trien-3-beta-ol
- 9,10-Secocholesta-5,7,10(19)-trien-3-ol, (3beta,5Z,7E)-
- 9,10-Secocholesta-5,7,10(19)-trien-3-ol, (3β,5Z,7E)-
- 9,10-Secocholesta-5,7,10(19)-trien-3β-ol
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Vitamin D3
CAS:Stability Temperature Sensitive Applications Vitamin D3 is the vitamin that mediates intestinal calcium absorbtion, bone calcium metabolism and probably, muscle activity. It occurs in and is isolated from fish liver oils. Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. It modulates the proliferation and differentiation of both normal and cancer cells. It also has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Haussler, R., et al.: J. Biol. Chem., 247, 2328 (1972); Holick, M.F., Rec. Res. Canc. Res., 164, 3 (2003); Palmer, H.G., et al.: Cancer Res., 63, 7799 (2003); Welsh, J., et al.: J. Nutr., 133, 2425S (2003)Formula:C27H44OColor and Shape:WhiteMolecular weight:384.64Vitamin D3, ≥99%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C27H44OPurity:99%Color and Shape:White to light yellow, Crystalline powder or crystalsMolecular weight:384.65Cholecalciferol - 100IU/mg - contains 2.5g/kg active
CAS:Cholecalciferol - 100IU/mg - contains 2.5g/kg active is a chemical compound known as vitamin D3. It is derived primarily from cholesterol through photochemical synthesis in animal skin exposed to ultraviolet light. The product functions as a hormone regulator by modulating calcium and phosphorus metabolism within biological systems. This process is crucial for maintaining bone density and immune system efficacy. Cholecalciferol is extensively used in scientific research to explore its role in bone health, immune response modulation, and potential therapeutic applications for various diseases such as osteoporosis and autoimmune disorders. Its efficacy in these areas makes it a valuable tool for furthering understanding in endocrinology and pharmacology. Researchers often utilize this compound in in vitro and in vivo studies to elucidate molecular mechanisms and develop new therapeutic strategies.Formula:C27H44OPurity:Min. 95%Color and Shape:White PowderMolecular weight:384.64 g/molVitamin D Assay System Suitability
CAS:Diagnostic or lab reagents on a backing, prepared diagnostic or lab reagents whether or not on a backing, whether or not in the form of kits, nesoiColor and Shape:Colorless LiquidMolecular weight:203.09061Vitamin D3
CAS:Vitamin D3 (Cholecalciferol) , a naturally occurring form of vitamin D, activates an H305F/H397Y mutant vitamin D receptor (VDR).Formula:C27H44OPurity:97.81% - 99.93%Color and Shape:Fine Needles From Dilute Acetone Physical Description Fine Colorless Crystals Water Insoluble (Ntp 1992)Molecular weight:384.64Colecalciferol
CAS:ColecalciferolFormula:C27H44OPurity:99.7%Color and Shape:WhiteMolecular weight:384.33922Cholecalciferol
CAS:Formula:C27H44OPurity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:384.65Vitamin D3, 99%
CAS:Vitamin D3 is used as an essential mediator of intestinal calcium absorption and bone calcium metabolism. It is also used as a therapeutic vitamin. Further, it is used as a nutritional supplement and to fortify foods. In addition to this, it is used as pharmaceutical drug and used in the treatment of respiratory diseases involving chronic inflammation such as asthma. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C27H44OPurity:99%Color and Shape:White, Crystals or powder or crystalline powderMolecular weight:384.65Cholecalciferol, USP grade
CAS:Formula:C27H44OPurity:97.0 - 103.0 %Color and Shape:White to almost white crystalline powderMolecular weight:384.65Vitamin D3 - 0.5m IU/g=500000 IU/g
CAS:Vitamin D3 is a fat-soluble vitamin that can be obtained from some fish, mushrooms, and dairy products. The most common form of the vitamin is cholecalciferol (vitamin D3) which can be converted in the liver to calcidiol (25-hydroxycholecalciferol) and in the kidneys to calcitriol (1,25-dihydroxycholecalciferol). Vitamin D3 has been shown to have a positive effect on calcium absorption and bone mineralization. It also has important physiological functions such as regulation of cell growth and differentiation. The solubility of vitamin D3 is dependent on the presence of a hydroxy group at position 3' or 25'. This liquid chromatography method uses an experimental solubility data set for the determination of solubility data for compounds with a hydroxy group at position 3'.Formula:C27H44OPurity:Min. 95%Color and Shape:PowderMolecular weight:384.64 g/molVitamin D3 10 µg/mL in Acetonitrile
CAS:Controlled ProductFormula:C27H44OColor and Shape:Single SolutionMolecular weight:384.64Cholecalciferol
CAS:Formula:C27H44OPurity:97.0 - 103.0 %Color and Shape:White to almost white crystalline powderMolecular weight:384.65Cholecalciferol (Vitamin D3)
CAS:Other vitamins and their derivatives, nesoiFormula:C27H44OColor and Shape:White PowderMolecular weight:384.649,10-Secocholesta-5,7,10(19)-trien-3beta-ol
CAS:9,10-Secocholesta-5,7,10(19)-trien-3beta-ol is a secosteroid compound, which is predominantly derived from the photochemical conversion of 7-dehydrocholesterol in the skin upon exposure to ultraviolet B radiation. This compound undergoes a series of hepatic and renal hydroxylations to form active vitamin D metabolites, such as calcitriol. These active forms modulate calcium and phosphate homeostasis through a nuclear receptor-mediated mechanism that governs gene expression relevant to mineral metabolism. The primary application of 9,10-Secocholesta-5,7,10(19)-trien-3beta-ol and its derivatives is in the field of endocrinology and metabolism, particularly concerning bone health and the management of disorders such as rickets, osteomalacia, and osteoporosis. Additionally, its role in immune modulation and cell differentiation presents potential therapeutic avenues in immunology and oncology. Understanding the biosynthesis, metabolism, and receptor interactions of this secosteroid is critical for developing advanced therapeutic strategies for calcium-related pathologies and beyond. Its significance extends into nutritional sciences, illuminating the implications of vitamin D deficiency and necessitating advancements in supplementation strategies.Formula:C27H44OPurity:Min. 97 Area-%Color and Shape:White Yellow PowderMolecular weight:384.64 g/molCholecalciferol (Vitamin D3) for tissue culture, 97%
CAS:Formula:C27H44OPurity:min. 97%Color and Shape:White to off-white, Crystalline powder, Clear, Colorless to pale yellowMolecular weight:384.64
