BTK
BTK (Bruton's tyrosine kinase) inhibitors are compounds that specifically target and inhibit BTK, a crucial enzyme involved in B-cell receptor signaling and the regulation of angiogenesis. BTK plays a significant role in the proliferation and survival of cancer cells, particularly in hematological malignancies. By inhibiting BTK, these compounds can disrupt angiogenesis and tumor growth, making them valuable in cancer therapy. At CymitQuimica, we offer a range of high-quality BTK inhibitors to support your research in oncology, immunology, and angiogenesis.
Products of "BTK"
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JDB175
CAS:JDB175, a selective BTK inhibitor with oral bioavailability, demonstrates excellent penetration through the blood-brain barrier.Formula:C26H21F3N4O2Purity:98%Color and Shape:SolidMolecular weight:478.47Cinsebrutinib
CAS:Cinsebrutinib, a Bruton's tyrosine kinase inhibitor, holds potential for research in cancer treatment.Formula:C22H26FN3O2Purity:98%Color and Shape:SolidMolecular weight:383.46PROTAC BTK Degrader-6
CAS:PROTAC BTK Degrader-6 (Compound 15), with a DC50 of 3.18 nM, exhibits anti-inflammatory properties by inhibiting NF-κB activation and suppressing the expressionFormula:C45H47N11O6Purity:98%Color and Shape:SolidMolecular weight:837.92LFM-A13
CAS:LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR,Formula:C11H8Br2N2O2Purity:99.9%Color and Shape:SolidMolecular weight:360BTK-IN-27
CAS:BTK-IN-27 (example 8), a potent BTK inhibitor with an IC50 of 0.2 nM, demonstrates anti-proliferative effects in TMD8 cells with an IC50 of less than 5 nM.Formula:C31H35N7O2Purity:98%Color and Shape:SolidMolecular weight:537.66BTK-IN-16
CAS:BTK-IN-16 is a potential inhibitor of wild-type BTK and C481S mutants.BTK-IN-16 can be used to study various autoimmune diseases and cancers caused by BTK.Formula:C15H14N4O2Purity:99.04%Color and Shape:SoildMolecular weight:282.3AS-1763
CAS:AS-1763 is an orally available and selective BTK inhibitor with an IC50 of 0.85 nM.Formula:C33H31FN6O3Purity:98%Color and Shape:SolidMolecular weight:578.64ONO-4059 analog
CAS:ONO-4059 analog (ONO-WG-307)ue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.Formula:C25H24N6O3Purity:99.25%Color and Shape:SolidMolecular weight:456.5Ref: TM-T6921
1mg46.00€2mg59.00€5mg87.00€10mg144.00€25mg279.00€50mg462.00€100mg662.00€1mL*10mM (DMSO)96.00€BIIB129
CAS:BIIB129 is a selective and brain-penetrant BTK covalent inhibitor used to study B-cell proliferation-related diseases.Formula:C19H22N6O2Purity:98.56%Color and Shape:SolidMolecular weight:366.42Acalabrutinib enantiomer
CAS:R-Acalabrutinib, a BTK inhibitor,enantiomer, is researched for cancer, autoimmune diseases, and inflammation.Formula:C26H23N7O2Purity:96.68%Color and Shape:SolidMolecular weight:465.51Ref: TM-T67881
1mg77.00€5mg158.00€10mg225.00€25mg338.00€50mg475.00€100mg638.00€200mg845.00€1mL*10mM (DMSO)170.00€(±)-Zanubrutinib
CAS:(±)-Zanubrutinib ((±)-BGB-3111) is a potent and orally available Bruton's tyrosine kinase (Btk) inhibitor that demonstrates superior oral bioavailability,Formula:C27H29N5O3Purity:98.19%Color and Shape:SolidMolecular weight:471.55Ref: TM-TQ0039
1mg49.00€5mg97.00€10mg154.00€25mg270.00€50mg432.00€100mg620.00€500mg1,283.00€1mL*10mM (DMSO)106.00€SB-633825
CAS:SB-633825 can inhibit cancer cell growth and angiogenesis.Formula:C28H25N3O3SPurity:98%Color and Shape:SolidMolecular weight:483.58zanubrutinib
CAS:Zanubrutinib (BGB-3111) is an inhibitor of Bruton tyrosine kinase (BTK).Formula:C27H29N5O3Purity:99.24% - 99.74%Color and Shape:SolidMolecular weight:471.55Ref: TM-T7584
1mg63.00€5mg144.00€10mg250.00€25mg518.00€50mg777.00€100mg1,074.00€1mL*10mM (DMSO)150.00€CHMFL-BMX-078
CAS:CHMFL-BMX-078 is a highly potent and selective type II irreversible BMX kinase inhibitor with an IC50 of 11 nM.Formula:C33H35N7O6Purity:100%Color and Shape:SolidMolecular weight:625.67Tirabrutinib
CAS:Tirabrutinib, an oral Btk inhibitor (IC50=6.8 nM), crosses the BBB and halts B cell signaling for autoimmune and hematologic studies.Formula:C25H22N6O3Purity:99.75%Color and Shape:SolidMolecular weight:454.48N-piperidine Ibrutinib
CAS:N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively.Formula:C22H22N6OPurity:96.65%Color and Shape:SolidMolecular weight:386.45BTK inhibitor 17
CAS:BTK inhibitor 17 is a potent irreversible BTK inhibitor (IC50 = 2.1 nM). BTK inhibitor 17 can be used in rheumatoid arthritis studies.Formula:C25H24N6O3Purity:99.29% - 99.57%Color and Shape:SolidMolecular weight:456.5Ref: TM-T9706
1mg94.00€5mg170.00€10mg264.00€25mg424.00€50mg562.00€100mg787.00€200mg1,035.00€1mL*10mM (DMSO)170.00€NX-2127
CAS:NX-2127 (ETX2514 Triethylamine) is an orally active BTK inhibitor that induces degradation of mutant BTKC481S in cells.NX-2127 has potent antiproliferativeFormula:C39H45N9O5Purity:98.11%Color and Shape:SolidMolecular weight:719.83Avitinib
CAS:Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,Formula:C26H26FN7O2Purity:100%Color and Shape:SolidMolecular weight:487.53PCI 29732
CAS:PCI 29732 is a selective and irreversible Btk inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay.Formula:C22H21N5OPurity:99.81%Color and Shape:SolidMolecular weight:371.43Ref: TM-T4337
1mg40.00€2mg52.00€5mg88.00€10mg126.00€25mg240.00€50mg426.00€100mg627.00€1mL*10mM (DMSO)87.00€
