Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- Apoptosis inducer
- ASK
- BCL
- Caspase
- c-RET
- FOXO1
- IAP
- Mdm2
- p53
- PD-1/PD-L1
- PDK
- PERK
- Serine/threonin kinase
- Survivin
- TNF
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Products of "Apoptosis"
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Ethyl pyruvate
CAS:Ethyl pyruvate: aliphatic ester, neuroprotective, anti-inflammatory, antioxidative, and anti-apoptotic properties.Formula:C5H8O3Purity:99.86%Color and Shape:Clear To Yellow LiquidMolecular weight:116.12Bortezomib
CAS:Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.Formula:C19H25BN4O4Purity:100% - 99.97%Color and Shape:Yellow SolidMolecular weight:384.24Ref: TM-T2399
5mg52.00€10mg64.00€25mg80.00€50mg96.00€100mg144.00€200mg225.00€500mg373.00€1mL*10mM (DMSO)52.00€CDK2-IN-32
CDK2-IN-32 (Compound 5g) is a selective CDK2 inhibitor with an IC50 of 0.21 μM. It exhibits cytotoxicity towards Vero cells with an IC50 of 28.52 μM.Formula:C18H13Cl2N5O2Color and Shape:SolidMolecular weight:402.23Mitazalimab
CAS:Mitazalimab (ADC-1013/JNJ-64457107) is a CD40 agonist that stimulates T cells to attack tumors and remodels the tumor microenvironment.Purity:95% - 95%Color and Shape:LiquidPogostone
CAS:Pogostone: anti-bacterial/fungal, blocks T-cells, modulates cytokines, protects against gastric ulcers, boosts antioxidants/PGE2/NP-SH.Formula:C12H16O4Purity:98.46% - 99.03%Color and Shape:SolidMolecular weight:224.25Irigenin
CAS:Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the ExtraFormula:C18H16O8Purity:99.50% - 99.85%Color and Shape:SolidMolecular weight:360.31Ionomycin calcium
CAS:Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.Formula:C41H70CaO9Purity:98% - 98.11%Color and Shape:SolidMolecular weight:747.07RITA
CAS:RITA (NSC-652287) forms DNA-DNA/protein cross-links without DNA breaks; disrupts p53/Mdm2 like nutlin-3.Formula:C14H12O3S2Purity:97.76% - 98.85%Color and Shape:SolidMolecular weight:292.37Ref: TM-T1798
1mg35.00€2mg46.00€5mg66.00€10mg96.00€25mg188.00€50mg344.00€100mg509.00€200mg715.00€500mg1,093.00€1mL*10mM (DMSO)89.00€SKF-96365 hydrochloride
CAS:SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal YFormula:C22H27ClN2O3Purity:99.48% - 99.85%Color and Shape:SolidMolecular weight:402.91Ref: TM-T2170
5mg57.00€10mg86.00€25mg138.00€50mg243.00€100mg470.00€200mg717.00€500mg1,111.00€1mL*10mM (DMSO)63.00€Cerivastatin
CAS:Cerivastatin is an HMG-CoA reductase inhibitor with anticancer and lipid-lowering effects and can be used to study primary hyperlipidemia.Formula:C26H34FNO5Purity:98.93% - 99.31%Color and Shape:SolidMolecular weight:459.55Citicoline
CAS:Citicoline (CDP-Choline) is an intermediate in the synthesis of phosphatidylcholine, a component of cell membranes. Citicoline exerts neuroprotective effects.Formula:C14H26N4O11P2Purity:100% - 99.84%Color and Shape:White PowderMolecular weight:488.32Cucurbitacin D
CAS:Cucurbitacin D is a triterpenoid isolated from Ecballium elaterium (L.) with anticancer and antitumor activity and is used in the study of cervical cancer.Formula:C30H44O7Purity:97.69%Color and Shape:SolidMolecular weight:516.67Sonrotoclax TFA
Sonrotoclax TFA is an orally available and highly potent and selective Bcl-2 inhibitor of WT and G101V mutants with antitumor activity for the study of hematologic malignancies.Formula:C51H60F3N7O9SPurity:99.63%Color and Shape:SolidMolecular weight:1004.12HSP90-IN-33
HSP90-IN-33 (compound 24e) is an effective Hsp90 inhibitor, demonstrating dissociation constants (Kd) of ≥200 µM for Hsp90α and 7.3 µM for Hsp90β. This compound induces cellular apoptosis (apoptosis) and arrests the cell cycle at the G0/G1 phase. Additionally, HSP90-IN-33 reduces the protein expression of ERα, CDK4, and Akt.Formula:C21H25Cl2N5O2Color and Shape:SolidMolecular weight:450.36ONX 0914
CAS:Controlled ProductApplications ONX 0914 is a proteosome inhibitor known for treatming malignancies and more recently, effacaciously inducing apoptosis for cancers. Used in the treatment of autoimmune diseases. References Mulder, A. et a.L Transplantation, 95, 1331 (2013); Screen, M. et al.: J. Biol. Chem., 285, 40125 (2010);Formula:C31H40N4O7Color and Shape:NeatMolecular weight:580.67CFM 4
CAS:CFM 4 is a potent small molecule CARP-1/APC-2 antagonist that prevents CARP-1 from binding to APC-2, contributes to G2M cell cycle arrest, and induces apoptosisFormula:C22H16ClN3OSPurity:98.82%Color and Shape:SolidMolecular weight:405.9C6 Ceramide-13C2,d2
CAS:Controlled ProductApplications A biologically active, cell permeable, but nonphysiologic ceramide analog. It stimulates protein phosphatase 2A at concentrations as low as 10 nM and activiates MAP kinase. It induces apoptosis and inhibits glycoproptein traffic by the secretory pathway. References Dobrowsky, R.T., et al.: J. Biol. Chem., 268, 15523 (1993), Raines, M.A., et al.: J. Biol. Chem., 268, 14572 (1993), Jarvis, W.D., et al.: Proc. Natl. Acad. Sci. USA, 91, 73 (1994),Formula:C2213C2H45D2NO3Color and Shape:NeatMolecular weight:401.63Asparanin A
CAS:Asparanin A, an apoptosis inducer with anticancer properties, arrests the cell cycle in the G0/G1 phase via the mitochondria and PI3K/AKT signaling pathways.Formula:C39H64O13Purity:98%Color and Shape:SolidMolecular weight:740.92Trans-L-Diaminocyclohexane Oxalatoplatinum
CAS:Formula:C8H14N2O4PtPurity:98%Color and Shape:SolidMolecular weight:397.2858Calycosin
CAS:Calycosin modulates estrogen receptors, induces apoptosis in cancers, and shows skin-lightening by inhibiting tyrosinase (IC50: 38.4µM).Formula:C16H12O5Purity:100% - 99.26%Color and Shape:White PowderMolecular weight:284.26
