Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- Apoptosis inducer
- ASK
- BCL
- Caspase
- c-RET
- FOXO1
- IAP
- Mdm2
- p53
- PD-1/PD-L1
- PDK
- PERK
- Serine/threonin kinase
- Survivin
- TNF
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Products of "Apoptosis"
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Hydroxyurea
CAS:Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.Formula:CH4N2O2Purity:99.85% - 99.92%Color and Shape:SolidMolecular weight:76.05Mollugin
CAS:Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.Formula:C17H16O4Purity:98.31% - ≥95%Color and Shape:SolidMolecular weight:284.31HS-173
CAS:HS-173 is an effective PI3Kα inhibitor (IC50: 0.8 nM).Formula:C21H18N4O4SPurity:99.33% - 99.64%Color and Shape:SolidMolecular weight:422.46Polyphyllin I
CAS:Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,Formula:C44H70O16Purity:98% - 99.5%Color and Shape:SolidMolecular weight:855.02Deracoxib
CAS:Deracoxib (SC 46) is a selective COX-2 inhibitor, non-steroidal, non-narcotic anti-inflammatory drug with an IC50 of 70-150 μM for osteosarcoma cells.Formula:C17H14F3N3O3SPurity:100% - 99.81%Color and Shape:SolidMolecular weight:397.375-Methoxy-1-(methoxymethoxy)-2-methyl-naphthalene-d3
CAS:Controlled ProductApplications 5-Methoxy-1-(methoxymethoxy)-2-methyl-naphthalene-d3 is an intermediate in the synthesis of Plumbagin-d3 (P627002). Plumbagin-d3 is labelled Plumbagin (P627000) which induces apoptosis in cancer cells. It also inhibits NADPH oxidase 4 in a time- and dose-dependent manner. References Klotz, L., et al.: Molecules, 19 14902 (2014); Gupta, S., et al.: Cancer Metastasis Rev., 29, 405 (2010); Schramm, A., et al.: Vascul. Pharmacol., 56, 216 (2012)Formula:C14H13D3O3Color and Shape:NeatMolecular weight:235.29Afatinib Dimaleate
CAS:Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Formula:C32H33ClFN5O11Purity:100% - 98.11%Color and Shape:SolidMolecular weight:718.08Ref: TM-T1773
1g467.00€5mg40.00€10mg59.00€25mg87.00€50mg107.00€100mg140.00€200mg188.00€500mg313.00€1mL*10mM (DMSO)66.00€Eupatolide
CAS:Eupatolide, from Inula japonica flowers, has anti-inflammatory properties and aids in researching TRAIL resistance in breast cancer.Formula:C15H20O3Purity:98%Color and Shape:SolidMolecular weight:248.32(±)-Shikonin
CAS:Formula:C16H16O5Purity:>98.0%(HPLC)Color and Shape:Orange to Brown powder to crystalMolecular weight:288.302'-epi-2'-O-Acetylthevetin B
CAS:2'-Epi-2'-O-Acetylthevetin B (GHSC-74), a cardiac glycoside extractable from Cerbera manghas L.Formula:C44H68O19Purity:98%Color and Shape:SolidMolecular weight:901Fludarabine
CAS:Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation.Formula:C10H12FN5O4Purity:100% - 99.88%Color and Shape:White SolidMolecular weight:285.23Troglitazone
CAS:Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.Formula:C24H27NO5SPurity:98% - 99.62%Color and Shape:Yellow SolidMolecular weight:441.54Ref: TM-T3170
2mg42.00€5mg62.00€10mg88.00€25mg172.00€50mg305.00€100mg558.00€500mg1,169.00€1mL*10mM (DMSO)85.00€VER-50589
CAS:VER-50589 is a potent HSP90 inhibitor.Formula:C19H17ClN2O5Purity:100% - 99.96%Color and Shape:SolidMolecular weight:388.8Ref: TM-T2258
1mg42.00€5mg97.00€10mg159.00€25mg264.00€50mg404.00€100mg588.00€200mg832.00€1mL*10mM (DMSO)97.00€MI-1061
CAS:MI-1061 is a orally bioavailable inhibitor of MDM2 (MDM2-p53 interaction) (IC50=4.4 nM).Formula:C30H26Cl2FN3O4Color and Shape:SolidMolecular weight:582.45NLRP3-IN-72
CAS:NLRP3-IN-72 (Compound 2) is a benzimidazole derivative. It exhibits anti-inflammatory and antioxidant properties, with an IC50 of 0.3 μM for NLRP3 IL-1β, a PD50 of 0.4 μM for protection against cell pyroptosis, and an EC50 of 0.6 μM for inducing HO-1.Formula:C19H20FN5OColor and Shape:SolidMolecular weight:353.393Tripterin
CAS:Tripterin (Celastrol) is an proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with antioxidant and anti-inflammatory effects.Formula:C29H38O4Purity:98.56% - 99.8%Color and Shape:Red Crystalline PowderMolecular weight:450.61Oncrasin-1
CAS:Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrationsFormula:C16H12ClNOPurity:99.75%Color and Shape:SolidMolecular weight:269.73Bendamustine hydrochloride
CAS:Bendamustine hydrochloride (EP-3101) (IC50 of 50 μM) is an alkylating agent associated with DNA damage.Formula:C16H21Cl2N3O2·HClPurity:97.71%Color and Shape:SolidMolecular weight:394.72Ferroptosis-IN-3
Ferroptosis-IN-3 (Compound 25), a ferroptosis inhibitor, demonstrates potent activity by inhibiting RSL3-induced ferroptosis in HT-1080 cells (EC50: 8.6 nM).Purity:98%Color and Shape:Odour Solid
