p53
p53 inhibitors target the p53 protein, a tumor suppressor that plays a crucial role in regulating the cell cycle, DNA repair, and apoptosis. While p53 is often mutated or inactivated in cancer cells, its inhibition is sometimes necessary to protect healthy cells from apoptosis during certain treatments. On the other hand, restoring p53 function in tumors can lead to cancer cell apoptosis. Research into p53 inhibitors is complex and significant for both understanding cancer mechanisms and developing new therapies. At CymitQuimica, we provide a selection of high-quality p53 inhibitors and modulators to support your research in cancer biology, apoptosis, and therapeutic development.
Products of "p53"
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BML-259
CAS:BML-259 inhibits CDK5/CDK2 (IC50: 64/98 nM) for cancer and neurodegeneration research.Formula:C14H16N2OSPurity:99.68%Color and Shape:SolidMolecular weight:260.35Ref: TM-T36964
5mg50.00€10mg85.00€25mg169.00€50mg279.00€100mg487.00€500mg1,035.00€1mL*10mM (DMSO)52.00€CT-1
CAS:CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.Formula:C29H23F3N4OPurity:99.24%Color and Shape:SolidMolecular weight:500.51LLY-507
CAS:LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2.Formula:C36H42N6OPurity:99.56% - 99.93%Color and Shape:SolidMolecular weight:574.76Ref: TM-T6879
1mg44.00€2mg55.00€5mg85.00€10mg138.00€25mg304.00€50mg552.00€100mg787.00€1mL*10mM (DMSO)110.00€HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi), Biotinylated
p53 is a tumor suppressor protein.Color and Shape:Odour Lyophilized Powder(S)-10-Hydroxycamptothecin
CAS:(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.Formula:C20H16N2O5Purity:99.09% - 99.81%Color and Shape:SolidMolecular weight:364.35HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi)
p53 is a tumor suppressor protein.Color and Shape:Odour Lyophilized PowderLeptomycin B
CAS:Leptomycin B: potent CRM1 inhibitor, blocks protein nuclear export and cell cycle, antifungal, modifies cysteine.Formula:C33H48O6Purity:99.04% - 99.71%Color and Shape:White Crystalline SolidMolecular weight:540.73Ref: TM-T15735
1mg202.00€2mg341.00€5mg620.00€10mg882.00€25mg1,320.00€50mg1,776.00€100mg2,403.00€1mL*10mM (DMSO)283.00€SLMP53-1
CAS:SLMP53-1 is a p53 activator with anti-tumor activity, activates reprogramming of glucose metabolism, and interferes with angiogenesis and migrationFormula:C20H18N2O2Purity:99.64%Color and Shape:SolidMolecular weight:318.37Ref: TM-T60839
1mg126.00€5mg298.00€10mg487.00€25mg938.00€50mg1,568.00€100mg2,517.00€1mL*10mM (DMSO)35.00€NSC 66811
CAS:NSC 66811 inhibits MDM2-p53 interaction with 120 nM affinity, activating p53 in cancer cells.Formula:C23H20N2OPurity:96.94%Color and Shape:SolidMolecular weight:340.42NSC 146109 hydrochloride
CAS:NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.Formula:C17H17ClN2SPurity:97.03%Color and Shape:SolidMolecular weight:316.85UNC0321
CAS:UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.Formula:C27H45N7O3Purity:99.25%Color and Shape:SolidMolecular weight:515.69O6-Benzylguanine
CAS:O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.Formula:C12H11N5OPurity:98.90%Color and Shape:Solid CrystallineMolecular weight:241.25BMH-7 HCl
BMH-7 HCl is a p53 activator, showing anti-cancer activity by activating the p53 pathway.Formula:C20H22ClN5OColor and Shape:SolidMolecular weight:383.88BAY 1892005
CAS:BAY 1892005 is a p53 protein modulator that targets the p53 condenser for the study of diseases associated with misfolded p53 proteinFormula:C11H8ClFN2OSPurity:99.62%Color and Shape:SoildMolecular weight:270.71BMH-7
CAS:BMH-7 (Histamine H4 receptor antagonist-2) is a p53 activator, demonstrating anti-cancer activity by activating the p53 pathway.Formula:C20H21N5OPurity:99.71%Color and Shape:SolidMolecular weight:347.41HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi)
p53 is a tumor suppressor protein.Color and Shape:Odour Lyophilized PowderPifithrin-α, p-Nitro, Cyclic
CAS:Pifithrin-α, p-Nitro, Cyclic (PFN-α) (PFN-α) is cell-permeable and active-form inhibitor of p53.Formula:C15H13N3O2SPurity:99.43%Color and Shape:SolidMolecular weight:299.35Ref: TM-T12472
1mg40.00€2mg52.00€5mg88.00€10mg126.00€25mg250.00€50mg406.00€100mg607.00€1mL*10mM (DMSO)87.00€Theaflavin 3,3'-digallate
CAS:Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancerFormula:C43H32O20Purity:98.71% - 99.86%Color and Shape:SolidMolecular weight:868.7BIX-01294 trihydrochloride
CAS:BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.Formula:C28H38N6O2·3HClPurity:99.41% - 99.95%Color and Shape:SolidMolecular weight:600.02Ref: TM-T1959
1mg44.00€2mg55.00€5mg71.00€10mg107.00€25mg192.00€50mg274.00€100mg492.00€500mg1,103.00€1mL*10mM (DMSO)139.00€Anti-Phospho-TP53 (Ser9) Antibody (4M602)
Anti-Phospho-TP53 (Ser9) Antibody (4M602) is an antibody targeting Phospho-TP53 (Ser9). Anti-Phospho-TP53 (Ser9) Antibody (4M602) can be used in ELISA, IF.Color and Shape:Odour LiquidMethylstat
CAS:Methylstat is a methyl ester prodrug of a Jumonji C domain-containing histone demethylase (JMJD) inhibitor that has favorable cell permeability.Formula:C28H31N3O6Purity:98.34% - 98.34%Color and Shape:SolidMolecular weight:505.56Anti-Phospho-TP53 (Ser33) Antibody (4K787)
Anti-Phospho-TP53 (Ser33) Antibody (4K787) is an antibody targeting Phospho-TP53 (Ser33). Anti-Phospho-TP53 (Ser33) Antibody (4K787) can be used in ELISA, IHC, IF.Color and Shape:Odour LiquidZMC1
CAS:NSC-319726 (ZMC1), a mutant p53R175 reactivator, suppresses growth of fibroblasts that expresses the p53R175 mutation (IC50 = 8 nM).Formula:C11H14N4SPurity:97.48% - 98.97%Color and Shape:SolidMolecular weight:234.32HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Monomer Protein, Human, MHC (His & Avi), Biotinylated
p53 is a tumor suppressor protein.Color and Shape:Odour Lyophilized PowderHLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
p53 is a tumor suppressor protein.Color and Shape:Odour Lyophilized Powder
