BCL
BCL inhibitors are compounds that target the BCL-2 family of proteins, which play a key role in the regulation of apoptosis. The BCL-2 family includes both pro-apoptotic and anti-apoptotic members that control the mitochondrial pathway of apoptosis. Inhibiting anti-apoptotic BCL-2 proteins can promote cell death in cancer cells, making BCL inhibitors crucial in cancer therapy research. At CymitQuimica, we provide a comprehensive selection of high-quality BCL inhibitors to support your research in cancer, apoptosis, and cell biology.
Products of "BCL"
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Cimidahurinine
CAS:Cimidahurinine can attenuate Doxorubicin (DOX)-induced cardiotoxicity in a dose-dependent manner with EC50 values of 45.79 uM; it protects againstFormula:C14H20O8Purity:98%Color and Shape:SolidMolecular weight:316.3Mcl1-IN-12
CAS:Mcl1-IN-12 has anti-tumor activity.It is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively.Formula:C45H46N4O6S2Purity:98%Color and Shape:SolidMolecular weight:803BCL6-IN-7
CAS:BCL6-IN-7 (BCL6 inhibitor-7) is a BCL6 corepressor-interaction inhibitor with potential antitumor activity, used in lymphoma research.Formula:C18H15ClN6OPurity:99.03%Color and Shape:SolidMolecular weight:366.82',3'-Dehydrosalannol
CAS:2',3'-Dehydrosalannol deters Spodptera litura and inhibits TNBC cell growth by blocking cathepsin signals.Formula:C32H42O8Purity:98%Color and Shape:SolidMolecular weight:554.68Mcl1-IN-9
CAS:Mcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) Inhibitor with an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM.Formula:C37H39ClN4O4Purity:98%Color and Shape:SolidMolecular weight:639.18MCL-1/BCL-2-IN-1
CAS:MCL-1/BCL-2-IN-2 (Compound Nap-1) is a potent and selective dual inhibitor of Mcl-1 and Bcl-2 with IC 50 s of 4.45 and 3.18 μM, respectively [1].Formula:C31H27BrN2O3SPurity:98%Color and Shape:SolidMolecular weight:587.53Myricanol
CAS:Myricanol can elicit growth inhibitory and cytotoxic effects on lung cancer cells, it can significantly decelerate tumor growth in vivo by inducing apoptosis.Formula:C21H26O5Purity:98%Color and Shape:SolidMolecular weight:358.434Bax activator-1
CAS:Bax activator-1 (compound 106) is a Bax activator. It induces Bax-dependent tumor cell apoptosis[1].Formula:C29H36N4O3Color and Shape:SolidMolecular weight:488.62Scutebarbatine A
CAS:Scutebarbatine A shows significant antitumor effects on A549 cells in vivo and in vitro via mitochondria-mediated apoptosis by up-regulating expressions ofFormula:C32H34N2O7Purity:98%Color and Shape:SolidMolecular weight:558.62Safflor Yellow A
CAS:Safflor Yellow A protects cultured rat cardiomyocytes against A/R injury, maybe via inhibiting cellular oxidative stress and apoptosis.Formula:C27H30O15Purity:98%Color and Shape:SolidMolecular weight:594.52Mcl-1 inhibitor 3
CAS:Mcl-1 inhibitor 3 shows good pharmacokinetic properties and excellent in vivo efficacy without toxicity.Mcl-1 inhibitor 3 is a highly potent and orally activateFormula:C40H52ClF2N5O7SPurity:98%Color and Shape:SolidMolecular weight:820.39BM 957
CAS:BM 957 is an effective Bcl-2 and Bcl-xL inhibitor (Kis: 1.2 and <1 nM; IC50s: 5.4 and 6.0 nM).Formula:C52H56ClF3N6O7S3Purity:98%Color and Shape:SolidMolecular weight:1065.68
