Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase
- CDK
- Cell Cycle Arrest
- Chk
- c-Myc
- Dynamin
- DYRK
- Ferroptosis
- HSP
- Integrin
- Kinesin
- KSP
- LIM Kinase
- Microtubule Associated
- PKC
- PLK
- Rho
- ROCK
- Wee1
Show 11 more subcategories
Products of "Cell Cycle/Checkpoint"
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L 888607 Racemate
CAS:L 888607 Racemate blocks DP1 and TP receptors with 132 nM and 17 nM affinity.Formula:C19H15ClFNO2SColor and Shape:SolidMolecular weight:375.84Arginine-glycine-aspartic acid
CAS:RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.Formula:C12H22N6O6Purity:99.11%Color and Shape:SolidMolecular weight:346.34Valategrast hydrochloride
CAS:Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.Formula:C30H33Cl4N3O4Purity:98%Color and Shape:SolidMolecular weight:641.41Ascamycin
CAS:Ascamycin: a Streptomyces-made antibiotic targeting Xanthomonas spp. MIC: 0.4-12.5 μg/mL for X. citri, oryzae, and phage.Formula:C13H18ClN7O7SPurity:99.29%Color and Shape:SolidMolecular weight:451.84Ref: TM-T14329
1mg333.00€5mg787.00€10mg1,074.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg4,655.00€1mL*10mM (DMSO)747.00€(E/Z)-ZINC09659342
CAS:(E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction.Formula:C23H15F3N2O4Purity:95.83%Color and Shape:SolidMolecular weight:440.37Ref: TM-T9986
1mg66.00€5mg145.00€10mg221.00€25mg378.00€50mg533.00€100mg718.00€200mg938.00€1mL*10mM (DMSO)160.00€Irigenin
CAS:Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the ExtraFormula:C18H16O8Purity:99.50% - 99.85%Color and Shape:SolidMolecular weight:360.315-BrdU
CAS:5-BrdU (Broxuridine) , a nucleoside analog, are used in the detection of proliferating cells and competes with thymidine for incorporation into DNA.Formula:C9H11BrN2O5Purity:99.54% - 99.87%Color and Shape:Crystals From Absolute Ethanol Physical Description White Crystalline Powder (Ntp 1992)Molecular weight:307.1Bersanlimab
CAS:Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:144.22 kDa5-Azacytidine
CAS:5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.Formula:C8H12N4O5Purity:99.31% - 99.79%Color and Shape:Crystals From Methanol Physical Description White Crystalline Powder (Ntp 1992)Molecular weight:244.2(R)-Atuveciclib
CAS:Atuveciclib (BAY-1143572) is a potent and highly selective, oral PTEFb / CDK9 inhibitor that inhibits CDK9 / CycT1 with an IC 50 of 13 nM [1].Formula:C18H18FN5O2SPurity:98%Color and Shape:SolidMolecular weight:387.43αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).Formula:C28H35F3N6O8SPurity:98%Color and Shape:SolidMolecular weight:672.67VER-00158411
CAS:VER-00158411 is a checkpoint kinase 1 and CHK2 inhibitor (IC50: 4.4 nM and 4.5 nM, respectively).Formula:C31H34N6O3Purity:98%Color and Shape:SolidMolecular weight:538.64NSC 617145
CAS:NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependentFormula:C13H10Cl4N2O4Purity:98.31% - 99.72%Color and Shape:SolidMolecular weight:400.04Ref: TM-T9168
1mg37.00€2mg52.00€5mg77.00€10mg96.00€25mg167.00€50mg240.00€100mg378.00€500mg889.00€1mL*10mM (DMSO)85.00€WRN inhibitor 15
WRN inhibitor 15 (Compound 9) is a WRN inhibitor with antitumor properties, displaying IC50 values of 37.9, 40.2, and 46.6 μM in PC3, LNCaP, and HeLa cells, respectively, making it suitable for prostate cancer research.Formula:C16H13F2N3OColor and Shape:SolidMolecular weight:301.29αvβ6-IN-1
αvβ6-IN-1 (compound 28) is an effective orally active inhibitor of αvβ6 integrin (αvβ6integrin), with a pIC50 value of 8.1. This compound shows potential for research in idiopathic pulmonary fibrosis.Formula:C25H32F2N4O3Color and Shape:SolidMolecular weight:474.543'-Deoxy-3'-fluoroadenosine
CAS:3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue with a wide range of anti-tumor and anti-viral activity, and has inhibitory effects on tick-borneFormula:C10H12FN5O3Purity:99.84%Color and Shape:SolidMolecular weight:269.23Synucleozid hydrochloride
CAS:Synucleozid hydrochloride inhibits the translation of the intrinsically disordered protein α-synuclein by targeting its structured mRNA.Formula:C22H21ClN6Purity:98.13%Color and Shape:SolidMolecular weight:404.9CNDAC hydrochloride
CAS:CNDAC hydrochloride, a nucleoside analog, is a metabolite of the sapacitabine.Formula:C10H13ClN4O4Purity:99.69%Color and Shape:SolidMolecular weight:288.69Ref: TM-T13621
1mg114.00€5mg274.00€10mg425.00€25mg702.00€50mg938.00€100mg1,311.00€1mL*10mM (DMSO)250.00€K858 (Racemic)
CAS:K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.Formula:C13H15N3O2SPurity:100%Color and Shape:SolidMolecular weight:277.34RX-3117
CAS:RX-3117 (fluorocyclopentenylcytosine) is a novel a cytidine analog.Formula:C10H12FN3O4Purity:99.55%Color and Shape:SolidMolecular weight:257.22Ref: TM-T16813
1mg157.00€2mg212.00€5mg309.00€10mg444.00€25mg728.00€50mg1,017.00€100mg1,378.00€1mL*10mM (DMSO)319.00€CDK7-IN-25
CAS:CDK7-IN-25 (CY-16-1) is a potent CDK7 inhibitor with an IC50 value of less than 1nM, utilized in cancer research [1].Formula:C33H32N6O3Purity:98%Color and Shape:SolidMolecular weight:560.65Betamethasone 17-benzoate
CAS:Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU).Formula:C29H33FO6Purity:98%Color and Shape:SolidMolecular weight:496.57CDK4-IN-2
CAS:CDK4-IN-2 (A17) is a potent inhibitor of CDK4, exhibiting K i and IC 50 values of less than 10 nM and is utilized in cancer research [1].Formula:C22H26F2N6O4SPurity:98%Color and Shape:SolidMolecular weight:508.54CDK2-IN-20
CDK2-IN-20 (compound 3b), a CDK2 inhibitor, exhibits cytotoxic effects on tumor cells with an IC50 ranging from 5.52-17.09 µM.Purity:98%Color and Shape:Odour SolidCDK4/9-IN-1
CAS:CDK4/9-IN-1 (Compound 29) is a selective dual inhibitor of CDK4 and CDK9, exhibiting IC50 values of 23 nM and 12 nM, respectively. It holds potential for use in cancer research.Formula:C22H34N6O2Color and Shape:SolidMolecular weight:414.544Spartalizumab
CAS:"Spartalizumab (PDR001), a humanized IgG4 monoclonal antibody, targets PD-1 to inhibit PD-L1/L2 interactions, useful in ATC research."Purity:SDS-PAGE:95.2%;SEC-HPLC:96.3%Color and Shape:LiquidMolecular weight:145.74 kDaPurvalanol B
CAS:Purvalanol B (NG 95) is a CDK inhibitor that inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively)Formula:C20H25ClN6O3Purity:98.95%Color and Shape:SolidMolecular weight:432.9Ref: TM-T7167
1mg38.00€5mg73.00€10mg95.00€25mg148.00€50mg215.00€100mg323.00€200mg487.00€1mL*10mM (DMSO)81.00€Visugromab
CAS:Visugromab, a GDF-15 neutralizing IgG4 monoclonal antibody (mAb), demonstrates potent efficacy in treating PD-1/PD-L1 relapsed/refractory metastatic solidPurity:98%Color and Shape:LiquidN6-(p-Methoxybenzyl)adenosine
CAS:Nucleoside Derivatives - 6-Modified purine nucleosides; Drugs and Inhibitors; plant growth regulator, plant hormoneFormula:C18H21N5O5Purity:99.79%Color and Shape:SolidMolecular weight:387.39L-Methioninamide hydrochloride
CAS:L-Methioninamide hydrochloride is a potent inhibitor of methionyl-tRNA synthetase that reduces the toxicity of CDDP.Formula:C5H13ClN2OSPurity:99.75%Color and Shape:SolidMolecular weight:184.692'-O-(2-Methoxyethyl)adenosine
CAS:2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.Formula:C13H19N5O5Purity:99.35%Color and Shape:SolidMolecular weight:325.32Uridine triphosphate 13C9,15N2 sodium
CAS:Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.Formula:C9H1415N2NaO15P3Color and Shape:SolidMolecular weight:517.04BI-1347
CAS:BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.Formula:C22H20N4OPurity:96.7% - 99.43%Color and Shape:SolidMolecular weight:356.42Ref: TM-T5405
1mg40.00€5mg88.00€10mg126.00€25mg240.00€50mg439.00€100mg647.00€500mg1,359.00€1mL*10mM (DMSO)87.00€Nofazinlimab
CAS:Nofazinlimab (CS1003) is a human anti-PD-1 IgG4 monoclonal antibody for the study of unresectable hepatocellular carcinoma (uHCC).Color and Shape:LiquidCDK9-IN-8
CAS:CDK9-IN-8 is a highly potent and selective CDK9 inhibitor (IC50: 12 nM).Formula:C31H32FN7O3Purity:98.77%Color and Shape:SolidMolecular weight:569.63RI-1
CAS:RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).Formula:C14H11Cl3N2O3Purity:99.3% - 99.62%Color and Shape:SolidMolecular weight:361.61Ganciclovir sodium
CAS:Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.Formula:C9H13N5NaO4Purity:99.47%Color and Shape:SolidMolecular weight:278.226-Hydroxy-DOPA
CAS:6-Hydroxy-DOPA is an allosteric inhibitor of RAD52, it inhibits proliferation of BRCA-deficient cancer cells in vitro and also inhibits APE1.Formula:C9H11NO5Purity:96.59% - 97.23%Color and Shape:SolidMolecular weight:213.19Adavosertib
CAS:Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.Formula:C27H32N8O2Purity:100% - 99.82%Color and Shape:SolidMolecular weight:500.6Ref: TM-T2077
5mg48.00€10mg70.00€25mg86.00€50mg92.00€100mg116.00€200mg170.00€500mg274.00€1mL*10mM (DMSO)52.00€Camrelizumab
CAS:Camrelizumab (SHR-1210) is a human IgG4-κ monoclonal antibody with high affinity and directed against PD-1.Camrelizumab binds PD-1 with a binding affinity of upPurity:98.6%Color and Shape:LiquidMolecular weight:143.7 kDaGSK2850163 (S enantiomer)
CAS:GSK2850163 (S enantiomer) is the inactive enantiomer of GSK2850163. GSK2850163 is an novel inhibitor of inositol-requiring enzyme-1 alpha (IRE1a).Formula:C24H29Cl2N3OPurity:98.40%Color and Shape:SolidMolecular weight:446.41Cyclo(RADfK)
CAS:Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.Formula:C28H43N9O7Purity:100%Color and Shape:SolidMolecular weight:617.7LDC-4297 HCl (1453834-21-3(free base))
LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.Formula:C23H29ClN8OPurity:100%Color and Shape:SolidMolecular weight:469.02Ref: TM-T4417
1mg59.00€2mg85.00€5mg97.00€10mg172.00€25mg339.00€50mg502.00€100mg728.00€1mL*10mM (DMSO)97.00€GRGDSPK
CAS:GRGDSPK (EMD 56574) is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.Formula:C28H49N11O11Purity:98%Color and Shape:SolidMolecular weight:715.76ZNL-05-044
ZNL-05-044, a CDK11 inhibitor, exhibits IC50 values of 0.23 μM for CDK11A and 0.27 μM for CDK11B, as determined by NanoBRET assay.Formula:C21H22Cl2N6OSPurity:98%Color and Shape:SolidMolecular weight:477.41MDEG-541
MDEG-541 is a potent MYC-MAX degrader that exhibits antiproliferative activity by downregulating the expression of GSPT1, MYC, GSPT2, and PLK1 proteins [1].Formula:C35H38N4O7SPurity:98%Color and Shape:SolidMolecular weight:658.76TAK-960
CAS:TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.Formula:C27H34F3N7O3Purity:97.06%Color and Shape:SolidMolecular weight:561.6Ref: TM-T7200
1mg64.00€2mg89.00€5mg120.00€10mg170.00€25mg294.00€50mg490.00€100mg710.00€1mL*10mM (DMSO)170.00€BRD32048
CAS:BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation.Formula:C16H22N6OPurity:99.69%Color and Shape:SolidMolecular weight:314.39Ref: TM-T23820
2mg52.00€5mg111.00€10mg175.00€25mg321.00€50mg512.00€100mg825.00€200mg1,111.00€1mL*10mM (DMSO)47.00€UNC9512
UNC9512 is a potent antagonist of the methyl-lysine reader protein 53BP1, which can be utilized to investigate the function of 53BP1 in DNA repair, gene editingFormula:C31H34N6O3Purity:98%Color and Shape:SolidMolecular weight:538.64(E/Z)-Rigosertib sodium
CAS:ON-01910 is a non-ATP-competitive PLK1 inhibitor(IC50 of 9 nM, in a cell-free assay).Formula:C21H24NNaO8SPurity:97.16% - 99.82%Color and Shape:SolidMolecular weight:473.47CCT129202
CAS:CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 μM, 0.198 μM and 0.227 μM, respectively.Formula:C23H25ClN8OSPurity:98.14%Color and Shape:SolidMolecular weight:497.02Elarofiban
CAS:Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.Formula:C22H32N4O4Purity:99.94%Color and Shape:SolidMolecular weight:416.51p21PBP
p21PBP, a peptide composed of 20 amino acids, serves as an inhibitor of DNA replication. It specifically binds to the purified proliferating cell nuclear antigen (PCNA) found in extracts from tumor cells. p21PBP holds potential for use in cancer research.Formula:C112H181N37O30SColor and Shape:SolidMolecular weight:2557.93Cdk2 Inhibitor II
CAS:Cdk2 Inhibitor II is a selective and potent CDK2 inhibitor50 at 60 nM.Formula:C14H11BrN4O3SPurity:98.38%Color and Shape:SolidMolecular weight:395.23Ref: TM-T36933
1mg103.00€2mg140.00€5mg202.00€10mg305.00€25mg512.00€50mg730.00€100mg998.00€500mg1,977.00€IXA4
CAS:IXA4 is a highly selective, nontoxic activator of IRE1/XBP1s and reduces APP secretion by activating IRE1.Formula:C24H28N4O4Purity:97.59% - 98.69%Color and Shape:SolidMolecular weight:436.5YK-2168
CAS:YK-2168 is a differentiated selective inhibitor of CDK9.Formula:C16H18ClN5Color and Shape:SolidMolecular weight:315.80PF07104091
CAS:PF07104091 inhibits CDK2, which may lead to cell cycle arrest, induce apoptosis and inhibit tumor cell proliferation. Cost-effective and quality-assured.Formula:C19H28N6O4Purity:98.61%Color and Shape:SolidMolecular weight:404.46Ref: TM-T9712
1mg354.00€2mg518.00€5mg823.00€10mg1,206.00€25mg1,795.00€50mg2,422.00€100mg3,258.00€1mL*10mM (DMSO)914.00€2'-Fluoro-2'-Deoxyadenosine
CAS:2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP).Formula:C10H12FN5O3Purity:99.35%Color and Shape:SolidMolecular weight:269.23BMS-265246
CAS:BMS-265246 is a potent and selective CDK1/2 inhibitor.Formula:C18H17F2N3O2Purity:98.77% - 99.55%Color and Shape:SolidMolecular weight:345.34Ref: TM-T2679
1mg35.00€5mg74.00€10mg116.00€25mg221.00€50mg335.00€100mg480.00€200mg652.00€1mL*10mM (DMSO)82.00€2'-Deoxy-5,6-dihydrouridine
CAS:2'-Deoxy-5,6-dihydrouridine is a nucleoside analog that contains a dihydro group in its molecular structure,commonly used in base excision related studies.Formula:C9H14N2O5Purity:99.75%Color and Shape:SolidMolecular weight:230.229-(β-D-Xylofuranosyl)adenine
CAS:9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine hasFormula:C10H13N5O4Purity:99.55%Color and Shape:SolidMolecular weight:267.24PVZB1194
CAS:PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis throughFormula:C13H9F4NO2SPurity:98%Color and Shape:SolidMolecular weight:319.28(1S,3R,5R)-PIM447 dihydrochloride
(1S,3R,5R)-PIM447 (dihydrochloride) an inhibitor of PIM(IC50 of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3).Formula:C24H25Cl2F3N4OPurity:98%Color and Shape:SolidMolecular weight:513.38(±)-Enitociclib
CAS:(±)-Enitociclib ((±)-BAY-1251152) is a racemic mixture of BAY-1251152. BAY-1251152 is highly selective inhibitor of PTEF/CDK9.Formula:C19H18F2N4O2SPurity:99.29%Color and Shape:SolidMolecular weight:404.43Ref: TM-T13467
1mg37.00€5mg88.00€10mg120.00€25mg216.00€50mg354.00€100mg567.00€200mg805.00€1mL*10mM (DMSO)87.00€CDK9 inhibitor HH1
CAS:CDK9 inhibitor HH1 (8019-9719) is an inhibitor of the human CDK2-cyclin A2 complex with an IC50 value of 2 μM.Formula:C13H15N3OSPurity:97.97%Color and Shape:SolidMolecular weight:261.34RP-6306
CAS:Lunresertib (RP-6306) is a potent, selective, and orally active PKMYT1 inhibitor with an IC50 of 14 nM.Cost-effective and quality-assured.Formula:C18H20N4O2Purity:98.41% - 99.28%Color and Shape:SolidMolecular weight:324.38CDK2 degrader 3
CAS:CDK2 degrader3 selectively degrades CDK2 and exhibits antitumor activity.Formula:C44H53ClN10O6SColor and Shape:SolidMolecular weight:885.47Lerociclib
CAS:Lerociclib (G1T38) is a CDK4/6 inhibitor with anticancer and antitumor activities, inhibiting CDK4/CyclinD1 and CDK6/CyclinD3.Formula:C26H34N8OPurity:99%Color and Shape:SolidMolecular weight:474.6360A
CAS:360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).Formula:C27H23N5O2Purity:98.68%Color and Shape:SolidMolecular weight:449.5Apcin
CAS:Apcin: potent APC/C(Cdc20) E3 ligase inhibitor, blocks substrate recognition & mitosis, synergizes with Ts-Arg-OMe.Formula:C13H14Cl3N7O4Purity:96.74%Color and Shape:SolidMolecular weight:438.65Ref: TM-T8561
1mg48.00€2mg63.00€5mg87.00€10mg140.00€25mg274.00€50mg472.00€100mg710.00€1mL*10mM (DMSO)97.00€Rosnilimab
CAS:Rosnilimab is a humanized IgG1-κ antibody that targets PD-1 [1] [2].Purity:98%Color and Shape:LiquidEHop-016
CAS:EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.Formula:C25H30N6OPurity:100% - 99.86%Color and Shape:SolidMolecular weight:430.55Ref: TM-T2427
5mg48.00€10mg73.00€25mg127.00€50mg213.00€100mg334.00€200mg492.00€500mg787.00€1mL*10mM (DMSO)52.00€YJ1206
CAS:YJ1206 is a highly potent and selective CDK12/13 PROTAC degrader oral, DNA damage and cell-cycle arrest,and inhibits the proliferation of prostate cancer cells.Formula:C49H52FN11O5Purity:97.14%Color and Shape:SolidMolecular weight:894.01MBM-17S
CAS:MBM-17S, a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM, effectively inhibits cancer cell proliferation by inducing cell cycle arrest andFormula:C36H40N6O10Purity:98%Color and Shape:SolidMolecular weight:716.74WRN inhibitor 2
CAS:WRN Inhibitor 2 (example 118), a potent inhibitor of the WRN (Werner Syndrome ATP-dependent helicase enzyme), exhibits a pIC50 value of 7.0 or greater [1].Formula:C15H11F3N2O5S2Purity:98%Color and Shape:SolidMolecular weight:420.38DMT-dG(ib) Phosphoramidite
CAS:DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.Formula:C44H54N7O8PPurity:99.74%Color and Shape:SolidMolecular weight:839.92SU-9516
CAS:SU9516 is a selectively potent ATP-competitive inhibitor of CDKs.Formula:C13H11N3O2Purity:99.59%Color and Shape:SolidMolecular weight:241.25Ref: TM-T8819
1mg90.00€5mg131.00€10mg170.00€25mg248.00€50mg321.00€100mg419.00€500mg938.00€1mL*10mM (DMSO)117.00€Aaptamine
CAS:Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner.Formula:C13H12N2O2Purity:98%Color and Shape:SolidMolecular weight:228.25c-Myc inhibitor 11
c-Myc inhibitor 11 (Compound 67e), a c-MYC inhibitor (p EC 50 : 6.4), exhibits high clearance, a moderate volume of distribution, and a short half-life in ratFormula:C20H22N6OPurity:98%Color and Shape:SolidMolecular weight:362.43AI-10-49
CAS:AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.Formula:C30H22F6N6O5Purity:97.14%Color and Shape:SolidMolecular weight:660.52Ref: TM-T6753
2mg40.00€5mg60.00€10mg96.00€25mg169.00€50mg245.00€100mg361.00€200mg512.00€1mL*10mM (DMSO)88.00€SR15006
CAS:SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).Formula:C16H20ClN3O4SPurity:99.78%Color and Shape:SoildMolecular weight:385.87Ref: TM-T60037
5mg39.00€10mg64.00€25mg117.00€50mg212.00€100mg316.00€200mg454.00€1mL*10mM (DMSO)62.00€SB-743921 hydrochloride
CAS:SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).Formula:C31H34Cl2N2O3Purity:95.58% - 99.70%Color and Shape:SolidMolecular weight:553.52Ref: TM-T2255
1mg42.00€5mg106.00€10mg163.00€25mg278.00€50mg429.00€100mg657.00€500mg1,501.00€1mL*10mM (DMSO)130.00€13-TP
13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.Formula:C12H19F2N6O12P3Color and Shape:SolidMolecular weight:570.23DL-Alanosine
CAS:DL-Alanosine is an amino acid analog with antitumor activity.Formula:C3H7N3O4Color and Shape:SolidMolecular weight:149.105Caracemide
CAS:Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.Formula:C6H11N3O4Purity:98.81%Color and Shape:SolidMolecular weight:189.17AURKA against 1
Compound Ac13, also termed AURKA against 1, acts as an inhibitor of the Aurora kinase (AURKA) with an IC50 of less than 0.5 nM, targeting the acetylation of endogenous lysine (K162) and exhibiting anti-tumor cell proliferation activity. The kinase activity of AURKA, acetylated at K162 and induced by AURKA against 1, is reversibly restored in HCT116 cells transfected with SIRT3.Formula:C28H32FN9O2Color and Shape:SolidMolecular weight:545.61PD-1-IN-17
CAS:PD-1-IN-17 is an inhibitor of programmed cell death-1 (PD-1). PD-1-IN-17 inhibits 92% splenocyte proliferation at 100 nM.Formula:C13H22N6O7Purity:99.6%Color and Shape:SolidMolecular weight:374.35PD-L1-IN-2
CAS:PD-L1-IN-2, a Naamidine J derivative, serves as a promising antineoplastic immunomodulator by hindering PD-L1 activity.Formula:C33H38N4O6Purity:98%Color and Shape:SolidMolecular weight:586.68Laromustine
CAS:Laromustine (VNP40101M) is a sulfonyl hydrolysis alkylation prodrug for cancer treatment with significant anticancer activity, inhibiting thioredoxin reductase.Formula:C6H14ClN3O5S2Color and Shape:SolidMolecular weight:307.785-Fluorouridine 5'-phosphate
CAS:5-Fluorouridine 5'-phosphate acts as an ODCase (uridine 5'-monophosphate decarboxylase) inhibitor, exhibiting a Ki value of 98 µM for human ODCase and 645 µM for Methanococcus jannaschii ODCase. This compound also shows inhibitory activity on leukemia and lymphoma cell lines, making it useful for cancer research studies.Formula:C9H12FN2O9PColor and Shape:SolidMolecular weight:342.172AS2863619 free base
CAS:AS2863619 free base enables the conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells.Formula:C16H12N8OColor and Shape:SolidMolecular weight:332.32KB-0742 dihydrochloride
CAS:KB-0742 dihydrochloride is a potent, selective and orally inhibitor of CDK9.Formula:C16H27Cl2N5Purity:99.79%Color and Shape:SolidMolecular weight:360.33Ref: TM-T9446
1mg96.00€2mg143.00€5mg235.00€10mg378.00€25mg630.00€50mg898.00€100mg1,216.00€1mL*10mM (DMSO)249.00€2-Keto-D-galactose
CAS:2-Keto-D-galactose inhibits DNA synthesis and inhibits the proliferation of in vitro grown Ehrlich ascites tumor cells.Formula:C6H10O6Purity:98%Color and Shape:SolidMolecular weight:178.14Zn(BQTC)
CAS:Zn(BQTC) inhibits mtDNA and nDNA, damages mitochondria/nuclei, triggers apoptosis, and targets A549R cancer cells.Formula:C30H36Cl2N5O3ZnPurity:98%Color and Shape:SolidMolecular weight:650.92Ocifisertib(CFI-400945 free base)
CAS:Ocifisertib (CFI-400945 free base) is a potent, selective and orally active inhibitor of polo-like kinase 4.Cost-effective and quality-assured.Formula:C33H34N4O3Purity:97.56% - 98.53%Color and Shape:SolidMolecular weight:534.65ATN-161 trifluoroacetate salt
CAS:ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.Formula:C25H36F3N9O10SPurity:98% - 99.98%Color and Shape:SolidMolecular weight:711.67Eciruciclib
CAS:Eciruciclib is an inhibitor of CDK with antitumor properties.Formula:C27H33FN8Purity:97.51%Color and Shape:SolidMolecular weight:488.6IBR2
CAS:IBR2 is a potent RAD51 inhibitor that disrupts DNA repair, inhibits cancer cell growth, and induces apoptosis.Formula:C24H20N2O2SPurity:96.15%Color and Shape:SolidMolecular weight:400.49Ref: TM-T11600
1mg35.00€5mg70.00€10mg111.00€25mg183.00€50mg259.00€100mg359.00€200mg532.00€1mL*10mM (DMSO)77.00€Tirofiban
CAS:Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.Formula:C22H36N2O5SPurity:99.87%Color and Shape:SolidMolecular weight:440.6Enoxacin
CAS:Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.Formula:C15H17FN4O3Purity:98.68% - 99.89%Color and Shape:Off-White To Yellow CrystalsMolecular weight:320.32
