Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase
- CDK
- Cell Cycle Arrest
- Chk
- c-Myc
- Dynamin
- DYRK
- Ferroptosis
- HSP
- Integrin
- Kinesin
- KSP
- LIM Kinase
- Microtubule Associated
- PKC
- PLK
- Rho
- ROCK
- Wee1
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Products of "Cell Cycle/Checkpoint"
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Indatuximab
Indatuximab is a chimeric antibody targeting CD13, used in the synthesis of ADC compound Indatuximab ravtansine.Color and Shape:LiquidMolecular weight:145.5 kDaHPH-15
CAS:HPH-15 is an anti-cell migration compound that inhibits cell movement by binding to hnRNP U or suppressing TGF-β. Additionally, it prevents epithelial-to-mesenchymal transition (EMT). HPH-15 holds potential for research in areas such as anti-tumor metastasis and anti-fibrosis.Formula:C19H31N3S4Color and Shape:SolidMolecular weight:429.735-Fluorouridine
CAS:5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine.Formula:C9H11FN2O6Purity:99.53% - 99.76%Color and Shape:White PowderMolecular weight:262.19ML264
CAS:ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.Formula:C17H21ClN2O4SPurity:99.33% - 99.45%Color and Shape:SolidMolecular weight:384.88CDK2-IN-30
CAS:CDK2-IN-30 (Formula (I)) is a CDK2 inhibitor with an IC50 of ≤20 nM, utilized primarily in tumor research.Formula:C18H25N7O3SColor and Shape:SolidMolecular weight:419.502-Fluoroadenine
CAS:2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.Formula:C5H4FN5Purity:99.49%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:153.12BS194
CAS:BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.Formula:C20H27N5O3Purity:99.85%Color and Shape:SolidMolecular weight:385.463,4-Dihydroxybenzylamine hydrobromide
CAS:3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.Formula:C7H10BrNO2Purity:97.28%Color and Shape:Light Beige Crystalline PowderMolecular weight:220.06BMS-688521
CAS:BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.Formula:C26H19Cl2N5O4Purity:98.87%Color and Shape:SolidMolecular weight:536.37Ref: TM-T14676
1mg183.00€5mg464.00€10mg655.00€25mg1,169.00€50mg1,539.00€100mg1,882.00€1mL*10mM (DMSO)547.00€LY3405105
CAS:LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-Formula:C26H39N7O3Purity:98.01%Color and Shape:SolidMolecular weight:497.63IMT1
CAS:IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.Formula:C21H21NO4Purity:98.07% - 98.14%Color and Shape:SolidMolecular weight:351.4Ref: TM-T8841
1mg81.00€5mg170.00€10mg301.00€25mg563.00€50mg805.00€100mg1,111.00€1mL*10mM (DMSO)188.00€PHI-101
CAS:PHI-101 is a checkpoint kinase 2 (Chk2) inhibitor that can be used for the study of refractory acute myeloid leukemia (AML) and ovarian cancer.Formula:C19H19FN4O2SPurity:99.40%Color and Shape:SolidMolecular weight:386.44Ref: TM-T81490
1mg173.00€5mg437.00€10mg702.00€25mg1,406.00€50mg2,262.00€100mg3,600.00€1mL*10mM (DMSO)469.00€SEL120-34A HCl
CAS:SEL120-34A HCl is a selective, orally available and ATP-competitive inhibitor of CDK8(CDK8/CycC and CDK19/CycC with IC50s of 4.4 nM and 10.4 nM , respectivelyFormula:C15H19Br2ClN4Purity:98.13% - 99.75%Color and Shape:SolidMolecular weight:450.6(S)-GNA-T-phosphoramidite
CAS:(S)-GNA-T-phosphoramidite is a nucleoside analog commonly used in the synthesis of other active compounds.Formula:C38H47N4O7PPurity:99.35%Color and Shape:SolidMolecular weight:702.78AZD-5438
CAS:AZD-5438 is an effective inhibitor of CDK, for CDK1(IC50=16 nM), CDK2(IC50=6 nM), CDK9(IC50=20 nM).Formula:C18H21N5O2SPurity:99.73% - 99.87%Color and Shape:SolidMolecular weight:371.46BUR1
CAS:BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.Formula:C16H17N5Purity:90%Color and Shape:SolidMolecular weight:279.34Obtustatin triacetate
Obtustatin triacetate, a 41-residue non-RGD disintegrin isolated from the venom of Vipera lebetina obtusa, serves as a potent and selective inhibitor of theFormula:C184H284N52O57S8·3C2H4O2Purity:99.51%Color and Shape:SolidMolecular weight:4573.21MYC-RIBOTAC
MYC-RIBOTAC, a ribonuclease-targeting chimera (RIBOTAC) specific to the MYC internal ribosome entry site (IRES), comprises an MYC mRNA-binding element tetheredFormula:C55H58N10O11SPurity:98%Color and Shape:SolidMolecular weight:1067.17Lerociclib dihydrochloride
CAS:Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3 and CDK4/Formula:C26H36Cl2N8OPurity:97.40%Color and Shape:SolidMolecular weight:547.52CCT241533 hydrochloride
CAS:CCT241533 hydrochloride is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).Formula:C23H28ClFN4O4Purity:97.13%Color and Shape:SolidMolecular weight:478.95Ref: TM-T10718L
1mg73.00€2mg96.00€5mg159.00€10mg240.00€25mg515.00€50mg852.00€100mg1,264.00€500mg2,547.00€1mL*10mM (DMSO)170.00€DMT-dU-CE Phosphoramidite
CAS:DMT-dU-CE Phosphoramidite is a nucleoside molecule commonly used for the synthesis and sequencing of DNA.Formula:C39H47N4O8PPurity:97.58%Color and Shape:SolidMolecular weight:730.79BMS-1001
CAS:BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).Formula:C35H34N2O7Purity:98.43%Color and Shape:SolidMolecular weight:594.7Abciximab
CAS:Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.Purity:SDS-PAGE:95.2%;SEC-HPLC:95.9%Color and Shape:LiquidMolecular weight:95.18 kDaVotoplam HCl
CAS:Votoplam HCl is a systemically acting gene splicing regulator that down-regulates the levels of huntingtin protein, which to inhibit Huntington's disease (HD).Formula:C21H26ClN9OPurity:99.49%Color and Shape:SoildMolecular weight:455.94
