Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase
- CDK
- Cell Cycle Arrest
- Chk
- c-Myc
- Dynamin
- DYRK
- Ferroptosis
- HSP
- Integrin
- Kinesin
- KSP
- LIM Kinase
- Microtubule Associated
- PKC
- PLK
- Rho
- ROCK
- Wee1
Show 11 more subcategories
Products of "Cell Cycle/Checkpoint"
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6-O-Methyl Guanosine
CAS:6-O-Methyl Guanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line.Formula:C11H15N5O5Purity:97.50%Color and Shape:SolidMolecular weight:297.27Lysidine
CAS:Lysidine (2-Methyl-2-iMidazoline) is a nucleoside rarely seen outside of tRNA. Lysidine has better translation fidelity.Formula:C4H8N2Purity:98%Color and Shape:Light Yellow To Off-White CrystallineMolecular weight:84.12Trifluridine
CAS:Trifluridine is a fluorinated thymidine analog with antineoplastic and antiviral properties, disrupting DNA and protein synthesis, leading to apoptosis.Formula:C10H11F3N2O5Purity:99.39% - 99.82%Color and Shape:White Crystalline PowderMolecular weight:296.2Haspin-IN-3
CAS:Haspin-IN-3 is a potent haspin inhibitor with an IC50 of 14 nM.Haspin-IN-3 has anticancer activity.Formula:C16H10N2O3Purity:98.78%Color and Shape:SolidMolecular weight:278.261-Methylcytosine
CAS:1-Methylcytosine (4-amino-1-methylpyrimidin-2(1H)-one) is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired withFormula:C5H7N3OPurity:100%Color and Shape:SolidMolecular weight:125.13MM41
CAS:MM41 is a human telomeric and gene promoter DNA quadruplex stabilizer with an IC50 of <10 nM against the MIA PaCa-2 pancreatic cancer cell line.Formula:C44H66N10O6Purity:97.13%Color and Shape:SolidMolecular weight:831.06Ref: TM-T60028
1mg52.00€5mg116.00€10mg178.00€25mg293.00€50mg393.00€100mg520.00€200mg712.00€1mL*10mM (DMSO)160.00€Kira8
CAS:Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity (IC50: 5.9 nM).Formula:C31H29ClN6O3SPurity:98.07%Color and Shape:SolidMolecular weight:601.12Ref: TM-T11762L
1mg87.00€5mg202.00€10mg305.00€25mg567.00€50mg810.00€100mg1,111.00€1mL*10mM (DMSO)269.00€SCH-1473759 hydrochloride
CAS:SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).Formula:C20H27ClN8OSPurity:98.29%Color and Shape:SolidMolecular weight:463Didox
CAS:Didox (NSC-324360), a synthetic RR inhibitor, lowers oxidative injury markers in HIV-related dementia.Formula:C7H7NO4Purity:96.85%Color and Shape:SolidMolecular weight:169.13DMTr-LNA-5MeU-3-CED-phosphoramidite
CAS:DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.Formula:C41H49N4O9PPurity:98.28%Color and Shape:SolidMolecular weight:772.82HMN-214
CAS:HMN-214 (IVX-214) is a potent PLK1 inhibitor with an average IC50 of 0.12 μM.Formula:C22H20N2O5SPurity:100% - 98.63%Color and Shape:SolidMolecular weight:424.47Ref: TM-T2438
1mg40.00€2mg52.00€5mg85.00€10mg124.00€25mg219.00€50mg350.00€100mg505.00€500mg1,121.00€1mL*10mM (DMSO)92.00€Durvalumab
CAS:Durvalumab is a humanized antibody for cancer, inhibiting PD-L1/PD-1 and CD80 interactions at very low concentrations.Purity:SDS-PAGE:97.2%;SEC-HPLC:95.3%Color and Shape:LiquidMolecular weight:146.03 kDaILK-IN-2
CAS:ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.Formula:C30H30F3N5OPurity:99.30%Color and Shape:SolidMolecular weight:533.59Ref: TM-T5488
1mg48.00€5mg97.00€10mg128.00€25mg162.00€50mg192.00€100mg281.00€200mg408.00€1mL*10mM (DMSO)137.00€Tibremciclib
CAS:Tibremciclib is a cyclin-dependent kinase 4 (CDK4) inhibitor that exhibits antineoplastic properties [1].Formula:C28H32F2N8Purity:98%Color and Shape:SolidMolecular weight:518.6MLS-573151
CAS:MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).Formula:C21H19N3O2SPurity:98.80%Color and Shape:SolidMolecular weight:377.46Ref: TM-T22106
2mg35.00€5mg52.00€10mg90.00€25mg170.00€50mg259.00€100mg383.00€200mg545.00€1mL*10mM (DMSO)58.00€DTP3
CAS:DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.Formula:C26H35N7O5Color and Shape:SolidMolecular weight:525.6BI-847325
CAS:BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.Formula:C29H28N4O2Purity:97.13% - 97.54%Color and Shape:SolidMolecular weight:464.56Ref: TM-T6785
1mg49.00€5mg97.00€10mg153.00€25mg296.00€50mg445.00€100mg660.00€200mg917.00€1mL*10mM (DMSO)97.00€CASIN
CAS:CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).Formula:C20H22N2OPurity:100% - 99.86%Color and Shape:SolidMolecular weight:306.4Ref: TM-T3971
1mg38.00€2mg49.00€5mg74.00€10mg120.00€25mg188.00€50mg283.00€100mg435.00€500mg938.00€1mL*10mM (DMSO)74.00€Kaempferitrin
CAS:Kaempferitrin has antidepressant effects via 5-HT1A, targets HeLa cells, promotes glucose control, and boosts immune function, including NK cells.Formula:C27H30O14Purity:98% - 99.59%Color and Shape:SolidMolecular weight:578.52Ref: TM-T3386
1mg50.00€5mg123.00€10mg207.00€25mg349.00€50mg515.00€100mg735.00€500mg1,483.00€1mL*10mM (DMSO)156.00€Nolatrexed
CAS:Nolatrexed is a thymidylate synthase inhibitor with potential anticancer activity.Formula:C14H12N4OSPurity:97.91%Color and Shape:SolidMolecular weight:284.34Ref: TM-T4228
1mg42.00€2mg50.00€5mg90.00€10mg148.00€25mg240.00€50mg430.00€100mg633.00€1mL*10mM (DMSO)96.00€
