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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Products of "Cell Cycle/Checkpoint"

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products per page.Found 974 products on this category.
  • Anti-Mouse PD-1 Antibody (RMP1-14)


    RMP1-14 is an IgG1-like immunoglobulin and anti-Mouse PD-1 antibody that blocks PD-1/PD-L1 signaling.
    Purity:14.68mg/ml - >95%
    Color and Shape:Odour Liquid

    Ref: TM-T78269

    1mg
    86.00€
    5mg
    264.00€
    10mg
    465.00€
    25mg
    883.00€
    50mg
    1,283.00€
    100mg
    1,710.00€
  • TREX1-IN-3

    CAS:
    TREX1-IN-3 (Compound 95) is an inhibitor of TREX1 and TREX2, with an IC50 of less than 0.1 μM for TREX1 and less than 1 μM for TREX2, as well as an EC50 of less than 1 μM for HCT116 cells. It is applicable for research in the field of cancer.
    Formula:C24H19ClN6O4
    Color and Shape:Solid
    Molecular weight:490.898

    Ref: TM-T205254

    10mg
    To inquire
    50mg
    To inquire
  • Lipustobart

    CAS:
    Lipustobart is an IgG4-kappa humanized monoclonal antibody targeting PDCD1 (programmed cell death 1, PD1, PD-1, CD279), with immunostimulant and antineoplastic
    Purity:98%
    Color and Shape:Liquid

    Ref: TM-T81928

    1mg
    To inquire
    5mg
    To inquire
  • 2',3'-Isopropylideneuridine

    CAS:
    2',3'-Isopropylideneuridine is a nucleoside derivative that has shown antiviral activity in several studies, particularly against Flaviviruses, such as HCV.
    Formula:C12H16N2O6
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:284.27

    Ref: TM-T71850

    2g
    37.00€
  • N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite

    CAS:
    N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenine nucleoside analog with potential vasodilator activity and anticancer activity.
    Formula:C47H52N7O7P
    Purity:98.59%
    Color and Shape:Solid
    Molecular weight:857.93

    Ref: TM-TNU1119

    1mg
    185.00€
    5mg
    459.00€
    10mg
    657.00€
    25mg
    1,026.00€
    50mg
    1,415.00€
    100mg
    1,872.00€
    500mg
    3,734.00€
  • DMT-2′Fluoro-dU Phosphoramidite

    CAS:
    DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.
    Formula:C39H46FN4O8P
    Purity:98.45%
    Color and Shape:Solid
    Molecular weight:748.78

    Ref: TM-T38958

    50mg
    34.00€
    1mL*10mM (DMSO)
    34.00€
  • Azelaoyl PAF

    CAS:
    Azelaoyl PAF is a potent PPARγ agonist that competitively binds thiazolidinediones.promotes the uptake of oxLDL by macrophages by upregulating CD36 expression.
    Formula:C33H66NO9P
    Color and Shape:Solid
    Molecular weight:651.85

    Ref: TM-T36180

    1mg
    To inquire
    5mg
    To inquire
    10mg
    To inquire
    500µg
    To inquire
  • Polθ-IN-5

    CAS:
    Polθ-IN-5 (Compound 139) is an inhibitor of DNA polymerase theta (Polθ) that exhibits antitumor activity.
    Formula:C23H18ClF2N7O3S
    Color and Shape:Solid
    Molecular weight:545.95

    Ref: TM-T200913

    25mg
    1,444.00€
    50mg
    1,882.00€
    100mg
    2,375.00€
  • CYC-116

    CAS:
    CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active
    Formula:C18H20N6OS
    Purity:96.6% - 97.59%
    Color and Shape:Solid
    Molecular weight:368.46

    Ref: TM-T6458

    2mg
    39.00€
    5mg
    56.00€
    10mg
    78.00€
    25mg
    135.00€
    50mg
    217.00€
    100mg
    358.00€
    500mg
    908.00€
    1mL*10mM (DMSO)
    49.00€
  • BAY1217389

    CAS:
    BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).
    Formula:C27H24F5N5O3
    Purity:95.71% - 98.78%
    Color and Shape:Solid
    Molecular weight:561.5

    Ref: TM-T3434

    1mg
    39.00€
    2mg
    51.00€
    5mg
    84.00€
    10mg
    114.00€
    25mg
    202.00€
    50mg
    303.00€
    1mL*10mM (DMSO)
    93.00€
  • Paprotrain

    CAS:
    Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.
    Formula:C16H11N3
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:245.28

    Ref: TM-T12359

    5mg
    48.00€
    10mg
    62.00€
    25mg
    97.00€
    50mg
    169.00€
    100mg
    250.00€
    200mg
    373.00€
    500mg
    612.00€
    1mL*10mM (DMSO)
    52.00€
  • CDK4/6-IN-2

    CAS:
    CDK4/6-IN-2 是一种CDK4和CDK6抑制剂,IC50分别为 2.7 和 16 nM。
    Formula:C27H32F2N8
    Purity:99.47%
    Color and Shape:Solid
    Molecular weight:506.59

    Ref: TM-T10736

    1mg
    96.00€
    5mg
    227.00€
    10mg
    359.00€
    25mg
    592.00€
    50mg
    835.00€
    100mg
    1,169.00€
  • Cytidine

    CAS:
    Cytidine (Cytosine-1-β-D-ribofuranoside) is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond.
    Formula:C9H13N3O5
    Purity:98.80% - 99.63%
    Color and Shape:Physical Description White Crystalline Powder (Ntp 1992)
    Molecular weight:243.22

    Ref: TM-T1591L

    1g
    37.00€
    5g
    70.00€
    10g
    92.00€
    1mL*10mM (DMSO)
    34.00€
  • T2AA

    CAS:
    T2AA (4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol) is an inhibitor of proliferating cell nuclear antigen (PCNA) with IC50 of 1 μM for PCNA/PIP-
    Formula:C15H15I2NO3
    Purity:98.19%
    Color and Shape:Solid
    Molecular weight:511.09

    Ref: TM-T35719

    5mg
    58.00€
    10mg
    93.00€
    25mg
    170.00€
    50mg
    278.00€
    100mg
    405.00€
    1mL*10mM (DMSO)
    64.00€
  • QR-6401

    CAS:
    QR-6401, a selective macrocyclic CDK2 inhibitor, is orally active with IC50 values of 0.37 nM for CDK2/E1, 10 nM for CDK9/T1, 22 nM for CDK1/A2, 34 nM for CDK6/
    Formula:C19H23N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:369.42

    Ref: TM-T79014

    5mg
    To inquire
    50mg
    To inquire
  • N,N-Dimethyl-2'-O-methylcytidine

    CAS:
    N,N-Dimethyl-2'-O-methylcytidine (N4, N4, 2'-O-Trimethylcytidine) is a purine nucleoside analogue with anti-cancer activity.
    Formula:C12H19N3O5
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:285.3

    Ref: TM-TNU0030

    1mg
    83.00€
    5mg
    180.00€
    10mg
    267.00€
    25mg
    450.00€
    50mg
    650.00€
    100mg
    928.00€
    200mg
    1,265.00€
  • 2'-O-Methyl-5-iodouridine

    CAS:
    2'-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a
    Formula:C10H13IN2O6
    Purity:98.32%
    Color and Shape:Solid
    Molecular weight:384.12

    Ref: TM-TNU0630

    1g
    160.00€
    50mg
    35.00€
    100mg
    46.00€
    500mg
    94.00€
  • Deoxycytidine triphosphate

    CAS:
    dCTP is a nucleotide used in DNA synthesis, PCR, cDNA creation, and sequencing.
    Formula:C9H16N3O13P3
    Purity:95.19%
    Color and Shape:Solid
    Molecular weight:467.16

    Ref: TM-T7520

    10mg
    87.00€
    50mg
    170.00€
  • Kif15-IN-1

    CAS:
    Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.
    Formula:C20H22N4O5S
    Purity:99.39% - 99.39%
    Color and Shape:Solid
    Molecular weight:430.48

    Ref: TM-T15661

    1mg
    475.00€
  • TC-Mps1-12

    CAS:
    TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .
    Formula:C17H20N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.38

    Ref: TM-T17007

    10mg
    To inquire
    50mg
    To inquire