Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase
- CDK
- Cell Cycle Arrest
- Chk
- c-Myc
- Dynamin
- DYRK
- Ferroptosis
- HSP
- Integrin
- Kinesin
- KSP
- LIM Kinase
- Microtubule Associated
- PKC
- PLK
- Rho
- ROCK
- Wee1
Show 11 more subcategories
Products of "Cell Cycle/Checkpoint"
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10074-G5
CAS:10074-G5 is an inhibitor of c-Myc-Max dimerization.Formula:C18H12N4O3Purity:97.22% - 99.67%Color and Shape:SolidMolecular weight:332.31Ref: TM-T3686
2mg42.00€5mg63.00€10mg88.00€25mg142.00€50mg225.00€100mg396.00€200mg565.00€500mg900.00€1mL*10mM (DMSO)69.00€9-Isopropylolomoucine
CAS:9-Isopropylolomoucine (N9-Isopropylolomoucine), a cell cycle protein-dependent kinase inhibitor, is a thiopurine.Formula:C17H22N6OPurity:100%Color and Shape:SolidMolecular weight:326.4Ref: TM-T23589
1mg333.00€5mg787.00€10mg1,074.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg4,655.00€1mL*10mM (DMSO)642.00€PD-1/PD-L1-IN-27
CAS:PD-1/PD-L1-IN-27: potent anti-cancer, IC50 134nM, minimal T cell harm, boosts CD8+ T cells, reduces fatigue.Formula:C44H35NO6Purity:98%Color and Shape:SolidMolecular weight:673.75Gantofiban
CAS:Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.Formula:C21H29N5O6Purity:99.21%Color and Shape:SolidMolecular weight:447.48CAN508
CAS:CAN508: potent CDK9/T1 inhibitor; IC50 0.35 μM, Cdk2/E; Ki 13.3 μM, IC50 20 μM; 38x selective; antitumor.Formula:C9H10N6OPurity:98.65%Color and Shape:SolidMolecular weight:218.22H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS:RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.Formula:C23H38N10O10Purity:100%Color and Shape:SolidMolecular weight:614.61CDK9 ligand 3
CAS:CDK9ligand 3 is a ligand for CDK9 and can be utilized in the synthesis of PROTAC degraders, specifically PROTAC CDK9degrader-11.Formula:C18H18BrCl2N5O3Color and Shape:SolidMolecular weight:503.177MLN0905
CAS:MLN0905 (PLK1 Inhibitor) is an effective PLK1 inhibitor(IC50=2 nM).Formula:C24H25F3N6SPurity:97.17% - 98%Color and Shape:SolidMolecular weight:486.56Cdk5 Substrate acetate
Cdk5, a serine/threonine kinase active in neurons, phosphorylates proteins like histone H1; its synthetic substrate has a Km of 5 µM.Formula:C55H103N15O14Purity:96.21%Color and Shape:SolidMolecular weight:1198.5R-10015
CAS:R-10015, potent LIMK inhibitor with 38 nM IC50 for LIMK1, targets ATP pocket, and serves as a broad-spectrum HIV antiviral.Formula:C20H19ClN6O2Purity:98.68%Color and Shape:SolidMolecular weight:410.86Ref: TM-T12609
1mg75.00€5mg170.00€10mg256.00€25mg423.00€50mg562.00€100mg792.00€200mg1,074.00€1mL*10mM (DMSO)182.00€PD-1/PD-L1-IN-52
PD-1/PD-L1-IN-52 (Compound Ⅲ-5) is an orally active inhibitor of PD-1/PD-L1 interaction, exhibiting an IC50 of 109.9 nM. It demonstrates antitumor activity in a C57BL/6 mouse model of MC38 colon carcinoma cells expressing human PD-1, achieving a tumor growth inhibition (TGI) rate of 49.6%.Color and Shape:Odour SolidAKI603
CAS:AKI603: Aurora A kinase blocker; IC50 12.3 nM; targets BCR-ABL-T315I resistance; halts leukemia cell growth.Formula:C19H23N9O2Purity:99.81%Color and Shape:SolidMolecular weight:409.45Ref: TM-T64338
1mg66.00€5mg145.00€10mg212.00€25mg380.00€50mg562.00€100mg792.00€200mg1,064.00€1mL*10mM (DMSO)160.00€Triazavirin
CAS:Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.Formula:C5H7N6NaO5SPurity:99.55%Color and Shape:SolidMolecular weight:286.2DNA Gyrase-IN-13
CAS:DNA Gyrase-IN-13 (compound 1b) is an inhibitor of DNA gyrase with bacteriostatic properties. It exhibits an IC50 of 1.81 μM against Staphylococcus aureus DNA gyrase.Formula:C15H21N3O3SColor and Shape:SolidMolecular weight:323.41Quarfloxin
CAS:Quarfloxin (CX-3543), a fluoroquinolone, inhibits neuroblastoma with nanomolar IC50, disrupting nucleolin and G-quadruplex DNA.Formula:C35H33FN6O3Purity:99.77%Color and Shape:SolidMolecular weight:604.67Ref: TM-T16703
1mg119.00€5mg169.00€10mg264.00€25mg487.00€50mg652.00€100mg847.00€1mL*10mM (DMSO)234.00€LY3295668
CAS:LY3295668 (AK-01) is a selective inhibitor of Aurora A with Kis of 0.8 nM and 1038 nM for Aurora A and B, respectively.Formula:C24H26ClF2N5O2Purity:99.44%Color and Shape:SolidMolecular weight:489.95iRGD peptide
CAS:iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.Formula:C35H57N13O14S2Purity:98.77%Color and Shape:SolidMolecular weight:948.04XL228
CAS:XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Formula:C22H31N9OPurity:99.07%Color and Shape:SolidMolecular weight:437.54Ref: TM-T17267
1mg56.00€2mg78.00€5mg99.00€10mg149.00€25mg258.00€50mg393.00€100mg582.00€1mL*10mM (DMSO)110.00€Sasanlimab
CAS:Sasanlimab (PF-06801591), a humanized IgG4-κ antibody, selectively targets PD-1 and is primarily produced in Chinese Hamster Ovary (CHO) cells [1].Purity:98%Color and Shape:Liquid(2S,3R)-Voruciclib
CAS:(2S,3R)-Voruciclib is the (2S,3R)-enantiomer of Voruciclib. It is an orally active CDK inhibitor.Formula:C22H19ClF3NO5Purity:98%Color and Shape:SolidMolecular weight:469.84
