Ferroptosis
Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid peroxides and iron-dependent oxidative stress. Unlike apoptosis, ferroptosis is not driven by caspases but rather by the failure of cellular antioxidant defenses, leading to cell death. Ferroptosis inhibitors and inducers are critical for studying this unique cell death pathway, which is implicated in various diseases, including cancer, neurodegeneration, and ischemia-reperfusion injury. At CymitQuimica, we offer a wide range of high-quality ferroptosis modulators to support your research in cell death mechanisms, oxidative stress, and disease pathology.
Products of "Ferroptosis"
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L-Glutathione reduced
CAS:L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals.Formula:C10H17N3O6SPurity:97.37% - 99.97%Color and Shape:SolidMolecular weight:307.32Tagitinin C
CAS:Tagitinin C is a sesquiterpene compound isolated from Tithonia diversifolia, an inducer of ferroptosis with anti-cancer activity.Formula:C19H24O6Color and Shape:SolidMolecular weight:348.39TBHQ
CAS:TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.Formula:C10H14O2Purity:99.17% - 99.53%Color and Shape:White Solid PowderMolecular weight:166.22Cycloheximide
CAS:Cycloheximide (Naramycin A) is an antimitotic compound and an inhibitor of DNA and protein synthesis.Formula:C15H23NO4Purity:95.08% - 99.95%Color and Shape:SolidMolecular weight:281.35L-Glutamic Acid
CAS:Formula:C5H9NO4Purity:>99.0%(T)Color and Shape:White powder to crystalMolecular weight:147.13Ferroptosis-IN-3
Ferroptosis-IN-3 (Compound 25), a ferroptosis inhibitor, demonstrates potent activity by inhibiting RSL3-induced ferroptosis in HT-1080 cells (EC50: 8.6 nM).Purity:98%Color and Shape:Odour SolidTrigonelline
CAS:Trigonelline (Trigenolline), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.Formula:C7H7NO2Purity:98% - 99.49%Color and Shape:Prisms Aqueous From Alcohol + Water SolidMolecular weight:137.14GDCNF-11
CAS:GDCNF-11, an HSP90-based HIM-PROTACGPX4 degrader, facilitates the ubiquitination and degradation of GPX4 through the HSP90 chaperone complex. This reduction in endogenous GPX4 induces ferroptosis in HT-1080 cells, with a DC50 value of 0.08 μM.Formula:C48H53Cl2N13O5SColor and Shape:SolidMolecular weight:994.99CDDO-Im
CAS:CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).Formula:C34H43N3O3Purity:100% - 98.3%Color and Shape:SolidMolecular weight:541.72Ref: TM-TQ0120
1mg37.00€5mg79.00€10mg111.00€25mg210.00€50mg338.00€100mg512.00€500mg1,093.00€1mL*10mM (DMSO)94.00€Rosiglitazone
CAS:Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.Formula:C18H19N3O3SPurity:98.61% - 99.87%Color and Shape:White To Off-White Crystalline PowderMolecular weight:357.43Gallic acid
CAS:Gallic acid (Benzoic acid) is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.Formula:C7H6O5Purity:99.57%Color and Shape:White Solid Solid Particulate/PowderMolecular weight:170.12Ciclopirox
CAS:Ciclopirox is an antifungal that chelates Fe3+ and Al3+, inhibiting enzymes and has antibacterial and anti-inflammatory effects.Formula:C12H17NO2Purity:97.72% - 99.41%Color and Shape:SolidMolecular weight:207.27FA16
FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16Formula:C22H27F3N4O2SPurity:99.75%Color and Shape:SolidMolecular weight:468.54Bay 11-7085
CAS:Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).Formula:C13H15NO2SPurity:99.76% - 99.83%Color and Shape:White SolidMolecular weight:249.33Ref: TM-T1934
2mg35.00€5mg50.00€10mg66.00€25mg85.00€50mg124.00€100mg197.00€200mg255.00€1mL*10mM (DMSO)62.00€Piperlongumine
CAS:Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.Formula:C17H19NO5Purity:97.03% - 99.89%Color and Shape:SolidMolecular weight:317.34Vamifeport
CAS:Vamifeport (VIT-2763), an inhibitor targeting iron transport proteins, improves anemia and erythropoiesis and can be studied β-thalassemiaFormula:C21H21FN6O2Purity:99.26%Color and Shape:SolidMolecular weight:408.43Ref: TM-T39520
1mg115.00€5mg274.00€10mg432.00€25mg730.00€50mg1,026.00€100mg1,378.00€1mL*10mM (DMSO)303.00€(-)-Epigallocatechin Gallate
CAS:(-)-Epigallocatechin Gallate (EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase.Formula:C22H18O11Purity:98.08% - 99.43%Color and Shape:Yellow PowderMolecular weight:458.37NADPH tetrasodium salt
CAS:NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety ofFormula:C21H26N7Na4O17P3Purity:100% - 99.65%Color and Shape:SolidMolecular weight:833.35CP-24879 hydrochloride
CAS:CP-24879 HCl, a Δ5D/Δ6D dual-inhibitor, reduces liver lipid buildup and inflammation.Formula:C11H18ClNOPurity:98.78%Color and Shape:SolidMolecular weight:215.72Ref: TM-T27061
1mg49.00€5mg92.00€10mg145.00€25mg274.00€50mg472.00€100mg687.00€500mg1,444.00€1mL*10mM (DMSO)96.00€GPX4-IN-7
GPX4-IN-7 (Compound 31), an indirubin derivative, serves as a ferroptosis inducer in colon cancer treatment.Formula:C25H23ClN4O4Purity:98%Color and Shape:SolidMolecular weight:478.93SRS11-92
CAS:SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1Formula:C22H28N2O2Purity:98.58%Color and Shape:SolidMolecular weight:352.47Ref: TM-T8922
1mg46.00€5mg80.00€10mg116.00€25mg227.00€50mg359.00€100mg550.00€500mg1,159.00€1mL*10mM (DMSO)105.00€FSEN1
CAS:FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM.Formula:C22H22BrN5OSPurity:98.56%Color and Shape:SolidMolecular weight:484.41Pro-GA
CAS:Pro-GA is a γ-glutamyl cyclotransferase (GGCT) inhibitor with cell permeability, acting as a diester prodrug with anticancer properties. GGCT is a key enzyme in glutathione metabolism and is involved in the ferroptosis pathway. Pro-GA exhibits an IC50 value of 57 μM against the bladder cancer cell line T24, making it useful for cancer research.Formula:C12H19NO7Color and Shape:SolidMolecular weight:289.28NYY-6a
NYY-6a is a ferroptosis (Ferroptosis) inhibitor, demonstrating significant suppression of RSL3-induced ferroptosis in 786-O and HT-1080 cells, with EC50 values of 52 nM and 50 nM, respectively. As a radical-trapping antioxidant (RTA), NYY-6a effectively reduces lipid peroxidation, comparable to ferrostatin-1 and liproxstatin-1, making it useful for research into ferroptosis-related pathologies.Formula:C23H22N2O3Color and Shape:SolidMolecular weight:374.43DL-Buthionine-(S,R)-sulfoximine
CAS:DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.Formula:C8H18N2O3SPurity:98% - 98.32%Color and Shape:White Fine PowderMolecular weight:222.31Rosiglitazone maleate
CAS:Rosiglitazone maleate (BRL 49653) is an oral antidiabetic and potential anticancer agent.Formula:C22H23N3O7SPurity:99.33% - 99.51%Color and Shape:Off-White SolidMolecular weight:473.5Zileuton
CAS:Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.Formula:C11H12N2O2SPurity:98.72% - 99.43%Color and Shape:Crystalline SolidMolecular weight:236.29Pravastatin sodium
CAS:Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.Formula:C23H35NaO7Purity:97.14%Color and Shape:White Crystalline PowderMolecular weight:446.52Nordihydroguaiaretic acid
CAS:Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.Formula:C18H22O4Purity:97.82% - 99.91%Color and Shape:SolidMolecular weight:302.36Hemin
CAS:Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.Formula:C34H32ClFeN4O4Purity:98.29% - 99.59%Color and Shape:Dark Purple Crystalline PowderMolecular weight:651.94Photosensitizer-5
Photosensitizer-5, a photodynamic agent, exhibits cytotoxicity towards HeLa and HepG2 cells, with IC50 values of 10.4 nM and 6.9 nM, respectively. It induces cell death through lipid peroxidation via an iron-independent ferroptosis pathway. Additionally, Photosensitizer-5 displays antitumor activity in HeLa-tumor-bearing mice.Formula:C35H26BF2IN4O2Color and Shape:SolidMolecular weight:710.32Ferrostatin-1
CAS:Formula:C15H22N2O2Purity:>98.0%(HPLC)Color and Shape:White to Amber to Dark purple powder to crystalMolecular weight:262.35Roxadustat
CAS:Roxadustat (FG-4592) is an orally bioavailable, hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), with potential anti-anemic activity.Formula:C19H16N2O5Purity:99% - 99.82%Color and Shape:SolidMolecular weight:352.34CIL56
CAS:CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS).Formula:C23H27N3O5S2Purity:99.46% - 99.91%Color and Shape:SolidMolecular weight:489.61Ref: TM-T4309
1mg37.00€2mg52.00€5mg79.00€10mg115.00€25mg188.00€50mg299.00€100mg459.00€1mL*10mM (DMSO)86.00€Cetzole
CAS:Cetzole (Compound 1) acts as an inducer of ferroptosis (iron-dependent cell death) through the accumulation of ROS, leading to cell death. The compound exhibits varying half-maximal cytotoxic concentrations (CC50) against several cell lines: 2.56 μM in NCI-H522, 10.31 μM in NCI-H522 GFP-SCL7A11 #8, 2.71 μM in NCI-H522 RV-GFP, 3.07 μM in HT-1080, 14.9 μM in NARF2, and 6.28 μM in MDA-MB-231. This highlights Cetzole's potential for research in cancer therapeutics.Formula:C11H11NOSColor and Shape:SolidMolecular weight:205.28Dopamine hydrochloride
CAS:Dopamine hydrochloride (ASL279) is a naturally occurring catecholamine formed by decarboxylation of dihydroxyphenylalanine and a precursor of norepinephrine andFormula:C8H12ClNO2Purity:99.56% - 99.76%Color and Shape:SolidMolecular weight:189.639Arteannuin B
CAS:1. Arteannuin B has potent antimalarial activity.Formula:C15H20O3Purity:98% - 99.8%Color and Shape:SolidMolecular weight:248.32L-Cystine
CAS:L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation ofFormula:C6H12N2O4S2Purity:99.59% - 99.85%Color and Shape:White Solid PowderMolecular weight:240.3Sorafenib
CAS:Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57Formula:C21H16ClF3N4O3Purity:98% - 99.89%Color and Shape:SolidMolecular weight:464.82Sulfasalazine
CAS:Formula:C18H14N4O5SPurity:98%Color and Shape:SolidMolecular weight:398.3925599999999ZX782
ZX782 acts as a GPX4 protein degrader and an inducer of ferroptosis (Ferroptosis), targeting GPX4 for destruction via both the ubiquitin-proteasome system and the autophagy-lysosome pathway. Following the degradation of GPX4 induced by ZX782, there is a significant increase in the accumulation of lipid reactive oxygen species (ROS) in HT1080 cells.Formula:C39H48ClN5O8Color and Shape:SolidMolecular weight:750.28Linagliptin
CAS:Linagliptin (BI 1356) is a potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity.Formula:C25H28N8O2Purity:99.15% - 99.95%Color and Shape:SolidMolecular weight:472.54Simvastatin
CAS:Formula:C25H38O5Purity:>97.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:418.57Artemisinin
CAS:Artemisinin (Qinghaosu) is a natural sesquiterpene lactone. Artemisinin has anti-malarial, neuroprotective and anti-tumor effects. Cost-effective and quality-assured.Formula:C15H22O5Purity:100% - 99.87%Color and Shape:Crystalline SolidMolecular weight:282.33Vildagliptin
CAS:Vildagliptin (LAF237), an oral DPP-4 inhibitor with hypoglycemic effects, is metabolized and excreted in urine.Formula:C17H25N3O2Purity:100% - 99.03%Color and Shape:White Crystalline PowderMolecular weight:303.4Gallic Acid Monohydrate
CAS:Gallic Acid Monohydrate, a natural polyhydroxyphenol, which inhibits the free radical scavenging effect of COX-2,antioxidant, anti-tumor, and antibacterial.Formula:C7H8O6Purity:98.02%Color and Shape:SolidMolecular weight:188.14Pioglitazone
CAS:Pioglitazone (U 72107) is an insulin sensitizing agent and thiazolidinedione that is indicated for the treatment of type 2 diabetes.Formula:C19H20N2O3SPurity:95% - 99.57%Color and Shape:White PowderMolecular weight:356.44D-glutamine
CAS:D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.Formula:C5H10N2O3Purity:99.99%Color and Shape:White Or Off-White PowderMolecular weight:146.14WITHAFERIN A
CAS:WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/Formula:C28H38O6Purity:97.41% - 99.83%Color and Shape:SolidMolecular weight:470.6Ref: TM-T5687
1mg85.00€5mg265.00€10mg393.00€25mg653.00€50mg929.00€100mg1,254.00€500mg2,517.00€1mL*10mM (DMSO)304.00€Ebselen
CAS:Formula:C13H9NOSePurity:>98.0%(GC)Color and Shape:Light orange to Yellow to Green powder to crystalMolecular weight:274.18DihydroarteMisinic acid
CAS:DihydroarteMisinic acid (Dihydro-Artmisinic Acid) is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinalFormula:C15H24O2Purity:99.06% - 99.17%Color and Shape:SolidMolecular weight:236.3584-B10
CAS:84-B10 provides protection in cisplatin-induced acute kidney injury, reversing lipid peroxidation accumulation and downregulation of key ferroptosis inhibitors.Formula:C25H22F3NO5Purity:99.76%Color and Shape:SolidMolecular weight:473.44Ref: TM-T75268
1mg52.00€5mg97.00€10mg169.00€25mg321.00€50mg494.00€100mg742.00€200mg1,008.00€1mL*10mM (DMSO)105.00€BODIPY 581/591 C11
CAS:BODIPY 581/591 C11 is a fluorescent radioactive probe used to indicate lipid peroxidation and antioxidant efficacy in model membrane systems and living cells.Formula:C30H35BF2N2O2Purity:98.83% - 98.90%Color and Shape:SolidMolecular weight:504.42L-Glutamic acid monosodium salt
CAS:L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.Formula:C5H8NO4·NaPurity:99.93%Color and Shape:White Solid CrystallineMolecular weight:169.11Ferrostatin-1
CAS:View and buy Ferrostatin-1 from TargetMol.Ferrostatin-1 is a potent ferroptosis inhibitor (EC50: 60 nM).Cited in 49 publications.Formula:C15H22N2O2Purity:96.1% - 99.68%Color and Shape:SolidMolecular weight:262.35Simvastatin
CAS:Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity.Formula:C25H38O5Purity:98.54% - 99.13%Color and Shape:SolidMolecular weight:418.57Ref: TM-T0687
10mg43.00€25mg58.00€50mg69.00€100mg106.00€200mg140.00€500mg270.00€1mL*10mM (DMSO)47.00€PRLX-93936 HCL
CAS:PRLX-93936 HCL is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin.Formula:C21H26Cl2N4O2Purity:100% - 99.78%Color and Shape:SolidMolecular weight:437.37Sorafenib tosylate
CAS:Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).Formula:C21H16ClF3N4O3·C7H8O3SPurity:99.2% - 99.94%Color and Shape:White To Off-White Crystalline PowderMolecular weight:637.03Piperazine Erastin
CAS:Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.Formula:C35H41ClN6O4Purity:97.74%Color and Shape:SolidMolecular weight:645.19Ref: TM-T16540
1mg96.00€5mg168.00€10mg283.00€25mg567.00€50mg929.00€100mg1,225.00€200mg1,681.00€500mg2,498.00€1mL*10mM (DMSO)240.00€Liproxstatin-1
CAS:Liproxstatin-1 is a potent and selective inhibitor of iron death (IC50=22 nM).Formula:C19H21ClN4Purity:97.11% - 99.9%Color and Shape:SolidMolecular weight:340.85Ref: TM-T2376
2mg52.00€5mg88.00€10mg137.00€25mg255.00€50mg411.00€100mg522.00€200mg750.00€1mL*10mM (DMSO)88.00€ML385
CAS:ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity.Formula:C29H25N3O4SPurity:100% - 99.98%Color and Shape:SolidMolecular weight:511.59Ref: TM-T4360
5mg51.00€10mg79.00€25mg153.00€50mg243.00€100mg376.00€200mg562.00€500mg899.00€1mL*10mM (DMSO)59.00€Cerivastatin sodium
CAS:Cerivastatin sodium (BAY W 6228 sodium) is an HMG-CoA reductase inhibitor with lipid-lowering activity that reduces LDL cholesterol levels.Formula:C26H33FNNaO5Purity:98%Color and Shape:SolidMolecular weight:481.53Ref: TM-T10767
1mg52.00€5mg136.00€10mg235.00€25mg565.00€50mg1,045.00€100mg1,890.00€1mL*10mM (DMSO)612.00€Dp44mT
CAS:Dp44mT, a effective iron chelator, has selective antitumor activity.Formula:C14H15N5SPurity:100% - 98.68%Color and Shape:SolidMolecular weight:285.37FINO2
CAS:FINO2, a strong ferroptosis trigger, blocks GPX4, oxidizes Fe2+, stable in different pH, causes lipid peroxidation.Formula:C15H28O3Purity:97.27%Color and Shape:SoildMolecular weight:256.38Imidazole ketone erastin
CAS:View and buy Imidazole ketone erastin from TargetMol.Imidazole ketone erastin (IKE) is an inducer of ferroptosis. It has inhibition of the system Xc- cystine/glutamate transporter.Cited in 22 publications.Formula:C35H35ClN6O5Purity:98.98% - 99.87%Color and Shape:SolidMolecular weight:655.14Ref: TM-T5523
1mg78.00€2mg97.00€5mg169.00€10mg216.00€25mg373.00€50mg567.00€100mg747.00€1mL*10mM (DMSO)182.00€Chrysosplenetin
CAS:Chrysosplenetin is a metabolic inhibitor of artemisinin.Formula:C19H18O8Purity:97.43% - 98.53%Color and Shape:SolidMolecular weight:374.34Ref: TM-TJS1159
1mg60.00€5mg127.00€10mg188.00€25mg348.00€50mg512.00€100mg730.00€500mg1,483.00€1mL*10mM (DMSO)226.00€Ethylenediaminetetraacetic acid trisodium salt
CAS:Ethylenediaminetetraacetic acid trisodium salt (EDTA Trisodium) used to bind metal ions in the chelation therapy.Formula:C10H13N2Na3O8Purity:99.92% - 99.96%Color and Shape:White CrystalsMolecular weight:358.19Ciclopirox olamine
CAS:Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.Formula:C14H24N2O3Purity:100% - 99.16%Color and Shape:White To Yellow Solid Solid Particulate/PowderMolecular weight:268.35Alogliptin Benzoate
CAS:Alogliptin Benzoate, a potent DPP-4 inhibitor with >10,000-fold selectivity over DPP-8/9, may also curb TLR-4-induced inflammation.Formula:C25H27N5O4Purity:100% - 99.94%Color and Shape:White PowderMolecular weight:461.51Ferrostatin-1 diyne
CAS:Ferrostatin-1 diyne (Fer-1 diyne) (compound 2) serves as an inhibitor of ferroptosis, accumulating in cellular lysosomes, mitochondria, and the endoplasmic reticulum. It notably inhibits ferroptosis independently of lysosomal and mitochondrial activity.Formula:C18H22N2O2Color and Shape:SolidMolecular weight:298.38Brusatol
CAS:Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.Formula:C26H32O11Purity:99.35% - 99.82%Color and Shape:SolidMolecular weight:520.53Ref: TM-TQ0211
1mg39.00€5mg94.00€10mg160.00€25mg311.00€50mg502.00€100mg715.00€200mg938.00€1mL*10mM (DMSO)107.00€BCP-T.A
CAS:BCP-T.A is an iron death inducer that acts by binding to GPX4.Formula:C23H19Cl2N3OSPurity:99.49%Color and Shape:SolidMolecular weight:456.39L-Glutamine
CAS:L-Glutamine (L-Glutamic acid 5-amide) , a non-essential amino acid, is synthesized from glutamic acid and ammonia.Formula:C5H10N2O3Purity:99.66% - 99.98%Color and Shape:Solid CrystallineMolecular weight:146.14Erastin
CAS:Formula:C30H31ClN4O4Purity:>98.0%(HPLC)(qNMR)Color and Shape:White to Light yellow powder to crystalMolecular weight:547.056-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic Acid
CAS:Formula:C14H18O4Purity:>98.0%(GC)(T)Color and Shape:White to Orange to Green powder to crystalineMolecular weight:250.29Sulfasalazine
CAS:Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.Formula:C18H14N4O5SPurity:98.00% - 99.28%Color and Shape:Minute Brownish-Yellow CrystalsMolecular weight:398.39Sulfasalazine
CAS:Formula:C18H14N4O5SPurity:>95.0%(T)(HPLC)Color and Shape:Light yellow to Amber to Dark green powder to crystalMolecular weight:398.39Ferroptosis inducer-4
Ferroptosisinducer-4 (Compound 5) is a phospholipid-based ferroptosis inducer featuring a terminal double bond at the sn-2 position. It exhibits significant cytotoxicity towards HT-1080 cells with an IC50 value of 18 μM. The toxicity mechanism involves the generation of lipid peroxides and oxidative damage to the cell membrane induced by the terminal double bond. Ferroptosisinducer-4 can be utilized in studies pertaining to the regulation of ferroptosis.Formula:C33H64NO7PColor and Shape:SolidMolecular weight:617.84L-Glutamic acid
CAS:L-Glutamic acid (Glutaminol) acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals.Formula:C5H9NO4Purity:99.14% - 99.55%Color and Shape:White Solid CrystallineMolecular weight:147.13Siramesine hydrochloride
CAS:Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibitFormula:C30H32ClFN2OPurity:100% - 99.75%Color and Shape:SolidMolecular weight:491.04Ref: TM-T1885
1mg60.00€2mg88.00€5mg111.00€10mg173.00€25mg354.00€50mg528.00€100mg743.00€1mL*10mM (DMSO)120.00€Lapatinib Ditosylate
CAS:Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).Formula:C29H26ClFN4O4S·2C7H8O3SPurity:99.41%Color and Shape:Yellow SolidMolecular weight:925.46PD146176
CAS:PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.Formula:C15H11NSPurity:98.00%Color and Shape:SolidMolecular weight:237.32Lovastatin
CAS:Lovastatin (MK-803) is an HMG-CoA reductase inhibitor. Lovastatin lowers cholesterol and is used as a lipid-lowering agent. Cost-effective and quality-assured.Formula:C24H36O5Purity:99.59% - 99.72%Color and Shape:The Substance Is A White-Yellowish To Yellow Powder Solid PowderMolecular weight:404.54Cisplatin
CAS:Cisplatin (CDDP) is a DNA cross-linking agent.Formula:Cl2H6N2PtPurity:97.13% - 99.63%Color and Shape:Orange-Yellow To Deep Yellow Solid Or PowderMolecular weight:300.04SP600125
CAS:SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitiveFormula:C14H8N2OPurity:97.63% - 99.58%Color and Shape:SolidMolecular weight:220.23Coenzyme Q10
CAS:Formula:C59H90O4Purity:>98.0%(HPLC)Color and Shape:Light yellow to Yellow to Orange powder to crystalMolecular weight:863.37Trolox
CAS:Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.Formula:C14H18O4Purity:98.84% - 99.80%Color and Shape:White To Fainly Beige Crystalline PowderMolecular weight:250.29Ferroptosis-IN-12
Ferroptosis-IN-12 (Cpd-A1) is an inhibitor of ferroptosis. It effectively suppresses ferroptosis in mouse renal tubular epithelial cells (mTECs) treated with Erastin and improves renal function in dose-dependent manners in mouse models of acute kidney injury (AKI) induced by ischemia/reperfusion (I/R) or cecal ligation and puncture (CLP). This compound also reduces renal tubular damage and eliminates inflammation. Exhibiting good plasma stability and high distribution in renal tissues during pharmacokinetic studies in mice, Ferroptosis-IN-12 shows promising potential for research in the field of AKI.Color and Shape:Odour SolidHDAC-IN-77
HDAC-IN-77 (HL-5s), an HDAC inhibitor, has the capability to induce ferroptosis and suppress the Nrf2/HO-1 signaling pathway. This compound is utilized in cancer research.Formula:C22H26N4O2SColor and Shape:SolidMolecular weight:410.53Rosiglitazone hydrochloride
CAS:Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.Formula:C18H19N3O3S·HClPurity:99.63% - 99.79%Color and Shape:SolidMolecular weight:393.89NADPH tetracyclohexanamine
CAS:NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.Formula:C45H82N11O17P3Purity:98.73% - 99.05%Color and Shape:SolidMolecular weight:1142.12Pifithrin-α hydrobromide
CAS:Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.Formula:C16H18N2OS·HBrPurity:100% - 98.54%Color and Shape:SolidMolecular weight:367.3DL-α-Tocopherol
CAS:DL-alpha-Tocopherol (Ephanyl) is a synthetic vitamin E that protects skin fibroblasts from the cytotoxic effects of UV light and has antioxidant properties.Formula:C29H50O2Purity:99.60%Color and Shape:Light Yellow Liquid ViscousMolecular weight:430.71SRS16-86
CAS:SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.Formula:C26H32N4O2Purity:99.85%Color and Shape:SolidMolecular weight:432.56Ref: TM-T9073
1mg37.00€2mg52.00€5mg77.00€10mg114.00€25mg215.00€50mg324.00€100mg484.00€1mL*10mM (DMSO)94.00€CuATSP
CAS:CuATSP is a potent free radical trapping antioxidant (RTA) and ferroptosis inhibitor inhibit lipid peroxidation, for (ALS) and Parkinson's disease.Formula:C18H18CuN6S2Purity:97.09%Color and Shape:SolidMolecular weight:446.05UAMC-3203 hydrochloride
CAS:UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.Formula:C25H38ClN5O2SPurity:99.62%Color and Shape:SolidMolecular weight:508.12Ref: TM-T8662
2mg49.00€5mg79.00€10mg111.00€25mg170.00€50mg202.00€100mg283.00€200mg420.00€1mL*10mM (DMSO)88.00€Deferasirox
CAS:Deferasirox (CGP-72670) is an oral iron chelating agent used to treat chronic iron overload.Formula:C21H15N3O4Purity:98.79% - 99.4%Color and Shape:SolidMolecular weight:373.36Lepadin H
CAS:Lepadin H, a marine alkaloid and ferroptosis inducer, exhibits significant cytotoxicity by promoting p53 expression, escalating ROS production, and enhancingFormula:C26H45NO3Purity:98%Color and Shape:SolidMolecular weight:419.64FIN56
CAS:FIN56 is a specific inducer of ferroptosis.Formula:C25H31N3O5S2Purity:98.39% - 99.78%Color and Shape:SolidMolecular weight:517.66
