Ferroptosis
Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid peroxides and iron-dependent oxidative stress. Unlike apoptosis, ferroptosis is not driven by caspases but rather by the failure of cellular antioxidant defenses, leading to cell death. Ferroptosis inhibitors and inducers are critical for studying this unique cell death pathway, which is implicated in various diseases, including cancer, neurodegeneration, and ischemia-reperfusion injury. At CymitQuimica, we offer a wide range of high-quality ferroptosis modulators to support your research in cell death mechanisms, oxidative stress, and disease pathology.
Products of "Ferroptosis"
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Troglitazone
CAS:Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.Formula:C24H27NO5SPurity:98% - 99.62%Color and Shape:Yellow SolidMolecular weight:441.54Ref: TM-T3170
2mg42.00€5mg62.00€10mg88.00€25mg172.00€50mg305.00€100mg558.00€500mg1,169.00€1mL*10mM (DMSO)85.00€(-)-Epicatechin
CAS:(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localizationFormula:C15H14O6Purity:97.34% - 98.55%Color and Shape:SolidMolecular weight:290.27Eprenetapopt
CAS:Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.Formula:C10H17NO3Purity:98.75% - 99.57%Color and Shape:SolidMolecular weight:199.25Ref: TM-T4414
5mg73.00€10mg105.00€25mg207.00€50mg368.00€100mg652.00€500mg1,320.00€1mL*10mM (DMSO)81.00€Ferroptosis-IN-1
Ferroptosis-IN-1, a diterpene derived from A.Formula:C22H34O5Purity:98%Color and Shape:SolidMolecular weight:378.5Levobupivacaine
CAS:Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide.Formula:C18H28N2OPurity:99.72%Color and Shape:SolidMolecular weight:288.43Ref: TM-T1787
5mg48.00€10mg63.00€25mg93.00€50mg136.00€100mg188.00€200mg283.00€500mg487.00€1mL*10mM (DMSO)49.00€Coenzyme Q9
CAS:Formula:C54H82O4Purity:>98.0%(HPLC)Color and Shape:Light yellow to Yellow to Orange powder to crystalMolecular weight:795.25PRIMA-1
CAS:PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.Formula:C9H15NO3Purity:99.22%Color and Shape:SolidMolecular weight:185.22Ref: TM-T6954
5mg51.00€10mg73.00€25mg140.00€50mg207.00€100mg368.00€200mg547.00€500mg877.00€1mL*10mM (DMSO)57.00€Baicalein
CAS:Formula:C15H10O5Purity:>98.0%(T)Color and Shape:Light yellow to Amber to Dark green powder to crystalMolecular weight:270.24CAR-2
CAS:CAR-2 is a BODIPY-based photosensitizer that induces ferroptosis in photodynamic therapy (PDT) by targeting the endoplasmic reticulum (ER) and lipid droplets (LD). It exhibits phototoxicity against breast cancer cells with an IC50 of 0.01-0.02 μM and demonstrates antitumor efficacy in a 4T1 xenograft mouse model.Formula:C27H23BF2I2N4O2Color and Shape:SolidMolecular weight:738.114RSL3
CAS:View and buy RSL3 from TargetMol.RSL3 is a VDAC-independent ferroptosis activator.Cited in 10 publications.Formula:C23H21ClN2O5Purity:98% - 99.96%Color and Shape:SolidMolecular weight:440.88Ref: TM-T3646
1g1,359.00€1mg39.00€2mg51.00€5mg79.00€10mg126.00€25mg258.00€50mg349.00€100mg459.00€500mg1,026.00€1mL*10mM (DMSO)74.00€Idebenone
CAS:Formula:C19H30O5Purity:>98.0%(T)(HPLC)Color and Shape:Light yellow to Brown powder to crystalMolecular weight:338.44Lapatinib ditosylate monohydrate
CAS:Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.Formula:C29H26ClFN4O4S·2(C7H8O3S)·H2OPurity:98% - 99.41%Color and Shape:Colourless To Light-Yellow CrystalMolecular weight:943.47Fluvastatin sodium
CAS:Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterolFormula:C24H25FNNaO4Purity:98.54% - 99.46%Color and Shape:Light Yellow Solid PowderMolecular weight:433.45TfR-1-IN-1
CAS:TfR-1-IN-1 is a TfR-1 inhibitor, also a Fe(III) salivary phenol complex, inducing apoptosis and inhibiting tumor and normal cell growth.Formula:C20H12ClF2FeN2O2Purity:96.96%Color and Shape:SolidMolecular weight:441.62Erastin2
CAS:Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.Formula:C36H35ClN4O4Purity:99.63%Color and Shape:SolidMolecular weight:623.14Ref: TM-T35994
1mg73.00€5mg160.00€10mg250.00€25mg424.00€50mg620.00€100mg800.00€200mg1,074.00€1mL*10mM (DMSO)224.00€GPX4 activator 2
CAS:GPX4 Activator 2 (Compound C3) serves as an activator of GPX4 and exhibits cardioprotective effects by inhibiting cellular iron death (ferroptosis) with an efficacy concentration (EC50) of 7.8 μM. It is used in the study of myocardial damage.Formula:C20H26N6O2SColor and Shape:SolidMolecular weight:414.52Cerivastatin
CAS:Cerivastatin is an HMG-CoA reductase inhibitor with anticancer and lipid-lowering effects and can be used to study primary hyperlipidemia.Formula:C26H34FNO5Purity:98.93% - 99.31%Color and Shape:SolidMolecular weight:459.55Ferroptosis-IN-15
CAS:Ferroptosis-IN-15 (compound 12) serves as an effective inhibitor of ferroptosis, exhibiting EC50 values of 0.76 μM and 0.67 μM in A375 cells and 786-O cells, respectively. It acts as a potential iron chelator and radical-scavenging antioxidant.Formula:C17H14O5Color and Shape:SolidMolecular weight:298.29Acetylcysteine
CAS:Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent.Formula:C5H9NO3SPurity:100% - 99.95%Color and Shape:Crystals From Water SolidMolecular weight:163.19
