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CDK

CDK

CDK (Cyclin-Dependent Kinase) inhibitors are compounds that block the activity of CDKs, a group of protein kinases that regulate the cell cycle, transcription, and other cellular processes. CDKs are activated by binding to cyclins, and their activity is crucial for the progression of cells through different phases of the cell cycle. Inhibiting CDKs can halt cell division, leading to cell cycle arrest and apoptosis, particularly in cancer cells where CDKs are often dysregulated. CDK inhibitors are widely used in cancer research and have therapeutic potential in treating various cancers. At CymitQuimica, we provide a comprehensive selection of high-quality CDK inhibitors to support your research in cell cycle control, cancer, and therapeutic development.

Products of "CDK"

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products per page.Found 289 products on this category.
  • (2S,3R)-Voruciclib

    CAS:
    (2S,3R)-Voruciclib is the (2S,3R)-enantiomer of Voruciclib. It is an orally active CDK inhibitor.
    Formula:C22H19ClF3NO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:469.84

    Ref: TM-T10096

    25mg
    2,015.00€
    50mg
    2,642.00€
    100mg
    3,515.00€
  • CDK1-IN-6


    CDK1-IN-6 (Ligand 3) is an effective inhibitor of CDK1 and shows potential for use in cancer research.
    Formula:C21H22N4O
    Color and Shape:Solid
    Molecular weight:346.43

    Ref: TM-T201825

    10mg
    To inquire
    50mg
    To inquire
  • TMX-2039

    CAS:
    TMX-2039 is a pan-CDK inhibitor that targets cell cycle CDKs (CDK1, CDK2, CDK4, CDK5, and CDK6) and transcription CDKs (CDK7 and CDK9), with IC50 values of 2.6, 1.0, 52.1, 0.5, 35.0, 32.5, and 25 nM, respectively. It serves as a ligand for the target protein in PROTAC applications.
    Formula:C17H20BrFN6O3S
    Color and Shape:Solid
    Molecular weight:487.347

    Ref: TM-T204484

    10mg
    To inquire
    50mg
    To inquire
  • SRI-29329

    CAS:
    SRI-29329 is a potent, specific inhibitor of CDC-like kinase (with IC50 of 78 nM, 16 nM and 86 nM for CLK1, CLK2 and CLK4, respectively).
    Formula:C20H26ClN7
    Purity:99.18%
    Color and Shape:Solid
    Molecular weight:399.92

    Ref: TM-T8801

    1mg
    92.00€
    5mg
    188.00€
    10mg
    306.00€
    25mg
    520.00€
    50mg
    748.00€
    100mg
    1,026.00€
    1mL*10mM (DMSO)
    215.00€
  • AZ5576

    CAS:
    AZ5576 is a potent and highly selective CDK9 inhibitor. AZ5576 can be used for the research of Hematological Malignancy [1].
    Formula:C21H24FN3O3
    Purity:99.88%
    Color and Shape:Soild
    Molecular weight:385.43

    Ref: TM-T60152

    1mg
    35.00€
    5mg
    80.00€
    10mg
    113.00€
    25mg
    221.00€
    50mg
    331.00€
    100mg
    475.00€
    500mg
    938.00€
    1mL*10mM (DMSO)
    87.00€
  • Senexin C

    CAS:
    Senexin C is a CDK8/19 inhibitor with anticancer activity.Senexin C inhibits the growth of MV4-11 leukemia cells.
    Formula:C28H27N5O
    Purity:97.91%
    Color and Shape:Solid
    Molecular weight:449.55

    Ref: TM-T62702

    1mg
    178.00€
    5mg
    454.00€
    1mL*10mM (DMSO)
    502.00€
  • OTS964 hydrochloride

    CAS:
    OTS964 hydrochloride (OTS964) is a potent and selective TOPK inhibitor with potential anticancer activity.
    Formula:C23H24N2O2S·HCl
    Purity:96.5% - 98.02%
    Color and Shape:Solid
    Molecular weight:428.97

    Ref: TM-T4135

    1mg
    46.00€
    2mg
    59.00€
    5mg
    93.00€
    10mg
    124.00€
    25mg
    197.00€
    50mg
    350.00€
    100mg
    522.00€
    1mL*10mM (DMSO)
    97.00€
  • CDK9-Cyclin T1 PPI-IN-1


    CDK9-Cyclin T1 PPI-IN-1 (Compound B19) is a selective inhibitor of the CDK9-Cyclin T1 protein-protein interaction (PPI), suppressing cell proliferation in TNBC
    Purity:98%
    Color and Shape:Odour Solid

    Ref: TM-T82758

    5mg
    To inquire
    50mg
    To inquire
  • CDK4-IN-1

    CAS:
    CDK4 inhibitor is a novel and specific CDK4/Cyclin D1 inhibitor with an IC50 of 10 nM; 1500 and 500 fold than CDK1/Cyclin B (IC50>15 uM) and CDK2/Cyclin A (IC50
    Formula:C22H29ClN8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:440.97

    Ref: TM-T2082

    25mg
    1,444.00€