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PLK

PLK

PLK (Polo-like Kinase) inhibitors target PLKs, a family of serine/threonine kinases that are essential for various stages of cell division, including mitotic entry, spindle assembly, and cytokinesis. PLKs are critical for the proper execution of the cell cycle, and their dysregulation is often associated with cancer. Inhibiting PLKs can induce cell cycle arrest and apoptosis in cancer cells, making these inhibitors important tools in cancer research and therapy. At CymitQuimica, we offer a range of high-quality PLK inhibitors to support your research in mitosis, cell cycle control, and oncology.

Products of "PLK"

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products per page.Found 23 products on this category.
  • Poloxin

    CAS:
    Poloxin is a non-ATP competitive Polo-like Kinase 1 inhibitor. It targets the polo-box domain (IC50: appr 4.8 μM).
    Formula:C18H19NO3
    Purity:99.19%
    Color and Shape:Solid
    Molecular weight:297.35

    Ref: TM-T16560

    5mg
    38.00€
    10mg
    52.00€
    25mg
    97.00€
    50mg
    160.00€
    100mg
    230.00€
    200mg
    341.00€
    1mL*10mM (DMSO)
    55.00€
  • HMN-176

    CAS:
    HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1).
    Formula:C20H18N2O4S
    Purity:98.92% - 98.99%
    Color and Shape:Solid
    Molecular weight:382.43

    Ref: TM-T3643

    1mg
    43.00€
    2mg
    56.00€
    5mg
    88.00€
    10mg
    119.00€
    25mg
    188.00€
    50mg
    350.00€
    100mg
    522.00€
    500mg
    1,130.00€
    1mL*10mM (DMSO)
    79.00€
  • Dihydrobaicalein

    CAS:
    Dihydrobaicalein is a natural product from Scutellaria baicalensis, a PLK1 inhibitor (IC50:6.3 μM).Dihydrobaicalein inhibits VRK2 and PLK2.
    Formula:C15H12O5
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:272.25

    Ref: TM-TN3848

    1mg
    185.00€
    5mg
    409.00€
    10mg
    605.00€
    25mg
    938.00€
    50mg
    1,293.00€