PKC
PKC (Protein Kinase C) inhibitors target the PKC family of serine/threonine kinases, which are involved in a wide range of cellular processes, including cell cycle regulation, apoptosis, and differentiation. PKC plays a key role in signal transduction pathways that influence cell proliferation and survival. Inhibiting PKC can lead to changes in cell cycle progression, making these inhibitors valuable in research related to cancer, neurobiology, and cardiovascular diseases. At CymitQuimica, we provide a diverse selection of high-quality PKC inhibitors to support your research in signal transduction, cell cycle regulation, and therapeutic development.
Products of "PKC"
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HIV-1 protease-IN-10
HIV-1 protease-IN-10 (Compound 2), exhibiting HIV-1 latency reversing activity (IC50: 0.22 μM), selectively binds to the PKCδ C1b domain (IC50: 0.69 μM) andFormula:C23H40O5Purity:98%Color and Shape:SolidMolecular weight:396.56PS315
CAS:PS315, a PS48 derivative, allosterically inhibits PKCζ/η (IC50: 10/30 μM), targeting aPKC's PIF-pocket, with anti-cancer properties.Formula:C23H19ClO2Purity:98%Color and Shape:SolidMolecular weight:362.85PKN1/2-IN-1
CAS:PKN1/2-IN-1 is a potent and selective PKN2 inhibitor, membrane permeability and anticancer.Protein kinase N proteins (PKN) are effectors of Rho GTPases.Formula:C14H15N3OColor and Shape:SolidMolecular weight:241.29Iso-H7 dihydrochloride
CAS:Iso-H7 dihydrochloride is a less potent inhibitor of phosphokinase C than H-7.Formula:C14H19Cl2N3O2SPurity:99.64%Color and Shape:White Crystalline SolidMolecular weight:364.29Ref: TM-T7501
2mg40.00€5mg52.00€10mg90.00€25mg138.00€50mg197.00€100mg293.00€200mg408.00€1mL*10mM (DMSO)66.00€BJE6-106
CAS:BJE6-106 (B106) is a potent, selective PKCδ inhibitor (IC50: 0.05 μM) and targets selectivity over classical PKCα (IC50: 50 μM).Formula:C26H23NO2Color and Shape:SolidMolecular weight:381.47PKCTheta-IN-2
CAS:PKCTheta-IN-2 (compound 14) is a potent and selective inhibitor of PKCθ, with an IC50 value of 0.25 nM. It demonstrates good selectivity across a broad range of kinases, including the PKC subfamily (30 kinases). Additionally, PKCTheta-IN-2 effectively inhibits the production of IL-2 in mice, where it exhibits an IC50 of 682 nM.Formula:C24H23N5O2Color and Shape:SolidMolecular weight:413.47PKC-iota inhibitor 1
CAS:PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)Formula:C21H22N6OPurity:98.82%Color and Shape:SolidMolecular weight:374.44Ref: TM-T8764
1mg113.00€2mg160.00€5mg230.00€10mg369.00€25mg615.00€50mg879.00€100mg1,198.00€500mg2,395.00€1mL*10mM (DMSO)240.00€Aurothiomalate tetramer sodium
Aurothiomalate tetramer sodium, a tetrameric form of Aurothiomalate sodium, functions as an anti-arthritis gold agent. It also acts as a potent and selective inhibitor of the oncogenic PKCι signaling pathway.Color and Shape:Odour SolidTAS-301
CAS:TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries.Formula:C23H19NO3Purity:99.69%Color and Shape:SolidMolecular weight:357.4Fasudil hydrochloride
CAS:Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.Formula:C14H18ClN3O2SPurity:100% - ≥95%Color and Shape:White SolidMolecular weight:327.83Enzastaurin
CAS:Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.Formula:C32H29N5O2Purity:100% - 99.24%Color and Shape:SolidMolecular weight:515.6Hypericin
CAS:Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.Formula:C30H16O8Purity:99.05% - ≥98%Color and Shape:Red-Coloured Anthraquinone-DerivativeMolecular weight:504.44Ref: TM-T6S0923
1mg57.00€5mg127.00€10mg182.00€25mg360.00€50mg532.00€100mg743.00€500mg1,510.00€1mL*10mM (DMSO)140.00€Decursinol angelate
CAS:Decursinol angelate is anti-tumor, anti-inflammatory, anti-oxidant, hepatoprotective, and inhibits VEGF and cancer cell invasion.Formula:C19H20O5Purity:99.93%Color and Shape:SolidMolecular weight:328.36R59949
CAS:R59949 is used as a Diacylglycerol kinase (DGK) inhibitor.Formula:C28H25F2N3OSPurity:97.04%Color and Shape:SolidMolecular weight:489.58Ref: TM-T26019
1mg47.00€5mg92.00€10mg145.00€25mg298.00€50mg465.00€100mg702.00€200mg938.00€1mL*10mM (DMSO)96.00€Protein kinase inhibitor H-7 dihydrochloride
CAS:Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor.Formula:C14H19Cl2N3O2SPurity:99.54%Color and Shape:White Crystalline SolidMolecular weight:364.29Bisindolylmaleimide IV
CAS:Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)Formula:C20H13N3O2Purity:98.83%Color and Shape:Dark Red SolidMolecular weight:327.341,2-Dimyristoyl-sn-glycerol
CAS:1,2-Dimyristoyl-sn-glycerol (1,2-DMG) is able to increase AChE activity by 35-40% at concentrations of 25 micrograms/ml in the parasite S. mansoni..Formula:C31H60O5Purity:99.49%Color and Shape:White Powder With LumpsMolecular weight:512.81Cercosporin
CAS:Cercosporin, produced by the plant pathogen Cercospora kikuchii and the elsinochromes, is a potent photosensitizer with a short activation wavelength. Cercosporin contains perylene quinone structural features essential for PKC activity (IC50: 0.6-1.3 μM).Formula:C29H26O10Purity:98%Color and Shape:SolidMolecular weight:534.51
