PKC
PKC (Protein Kinase C) inhibitors target the PKC family of serine/threonine kinases, which are involved in a wide range of cellular processes, including cell cycle regulation, apoptosis, and differentiation. PKC plays a key role in signal transduction pathways that influence cell proliferation and survival. Inhibiting PKC can lead to changes in cell cycle progression, making these inhibitors valuable in research related to cancer, neurobiology, and cardiovascular diseases. At CymitQuimica, we provide a diverse selection of high-quality PKC inhibitors to support your research in signal transduction, cell cycle regulation, and therapeutic development.
Products of "PKC"
Sort by
CGP60474
CAS:CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.Formula:C18H18ClN5OPurity:99.81%Color and Shape:SolidMolecular weight:355.82Ref: TM-T14943
1mg35.00€2mg48.00€5mg74.00€10mg97.00€25mg187.00€50mg331.00€100mg547.00€1mL*10mM (DMSO)82.00€HA-100
CAS:HA-100 is an inhibitor of protein kinaseFormula:C13H15N3O2SPurity:99.44%Color and Shape:Pale Yellow Crystalline SolidMolecular weight:277.34Taurochenodeoxycholic acid sodium
CAS:Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).Formula:C26H44NNaO6SPurity:98.23% - 99.45%Color and Shape:White To Off-White PowderMolecular weight:521.68Go 6983
CAS:Go 6983 is a pan-PKC inhibitor targeting PKCα, PKCβ, PKCγ, PKCδ, and PKCζ, exhibiting IC50 values of 7 nM, 7 nM, 6 nM, 10 nM, and 60 nM, respectively.Formula:C26H26N4O3Purity:98.41% - 99.04%Color and Shape:SolidMolecular weight:442.51Ref: TM-T6313
1mg43.00€2mg55.00€5mg84.00€10mg126.00€25mg245.00€50mg388.00€100mg563.00€1mL*10mM (DMSO)88.00€Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formula:C35H30N4O4Purity:100% - 99.47%Color and Shape:SolidMolecular weight:570.64Ref: TM-T3211
1mg51.00€5mg88.00€10mg126.00€25mg216.00€50mg328.00€100mg487.00€500mg1,093.00€1mL*10mM (DMSO)96.00€Ionomycin calcium
CAS:Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.Formula:C41H70CaO9Purity:98% - 98.11%Color and Shape:SolidMolecular weight:747.07AJH-836
CAS:AJH-836 is a compound that activates Munc13-1 and PKC ε/α, demonstrating a dissociation constant (Kd) of 4.5 nM for PKCα, and facilitates the translocation ofFormula:C22H38O5Purity:98%Color and Shape:SolidMolecular weight:382.53PKC-IN-1
CAS:PKC-IN-1 is an ATP-competitive and reversible conventional PKC enzymes inhibitor (PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε with IC50s of 2.3, 8.1, 7.6,Formula:C25H37FN8O2Purity:98% - 98.79%Color and Shape:SolidMolecular weight:500.61Bisindolylmaleimide III
CAS:Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6Formula:C23H20N4O2Purity:98.6%Color and Shape:SolidMolecular weight:384.43Phorbol 12,13-dibutyrate
CAS:Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that induces contraction of isolated rabbit vascular smooth muscle.Formula:C28H40O8Purity:100% - 99.32%Color and Shape:SolidMolecular weight:504.61Ref: TM-T16526
1mg62.00€5mg169.00€10mg283.00€25mg557.00€50mg795.00€100mg1,074.00€1mL*10mM (DMSO)180.00€VTX-27
CAS:VTX-27 is a selective inhibitor of protein kinase C θ (PKC θ) (Kis: 0.08 nM and 16 nM for PKC θ and PKC δ).Formula:C20H24ClFN6OPurity:99.49%Color and Shape:SolidMolecular weight:418.9Ref: TM-T13314
1mg93.00€2mg125.00€5mg244.00€10mg364.00€25mg562.00€50mg780.00€100mg1,035.00€1mL*10mM (DMSO)225.00€Ruboxistaurin hydrochloride
CAS:Ruboxistaurin HCl (LY 333531) selectively inhibits PKCβI/II with IC50 of 4.7/5.9 nM; much less effective on other PKC types and ATP-kinases.Formula:C28H28N4O3·HClPurity:98.44% - 99.22%Color and Shape:SolidMolecular weight:505.01Ref: TM-T3689
1mg71.00€2mg93.00€5mg157.00€10mg256.00€25mg513.00€50mg740.00€100mg1,035.00€500mg2,072.00€1mL*10mM (DMSO)202.00€K-252b
CAS:K-252b, an indolocarbazole derived from the actinomycete Nocardiopsis, functions as a protein kinase C (PKC) inhibitor.Formula:C26H19N3O5Purity:98%Color and Shape:Ready-To-Use SolutionMolecular weight:453.45Delcasertib
CAS:Delcasertib (KAI-9803) is a potent and selective inhibitor of δ-protein kinase C (δPKC).Formula:C120H199N45O34S2Purity:99.96%Color and Shape:SolidMolecular weight:2880.28Ref: TM-T11740
1mg202.00€5mg512.00€10mg740.00€25mg1,121.00€50mg1,539.00€100mg2,072.00€1mL*10mM (DMSO)1,691.00€1-Oleoyl-2-acetyl-sn-glycerol
CAS:1-Oleoyl-2-acetyl-sn-glycerol (1-oleoyl-2-acetyl-glycerol) is a PKC activator that induces superoxide production.Formula:C23H42O5Color and Shape:SolidMolecular weight:398.58Hispidin
CAS:Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective propertiesFormula:C13H10O5Purity:98.27%Color and Shape:White Crystalline PowderMolecular weight:246.22Ref: TM-T7792
1mg88.00€5mg187.00€10mg298.00€25mg533.00€50mg747.00€100mg1,017.00€1mL*10mM (DMSO)207.00€A-3 hydrochloride
CAS:A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.Formula:C12H14Cl2N2O2SPurity:99.32%Color and Shape:SolidMolecular weight:321.22Ref: TM-T14069
1mg35.00€5mg66.00€10mg96.00€25mg170.00€50mg274.00€100mg439.00€500mg938.00€1mL*10mM (DMSO)90.00€(8R)-8-Hydroxyepoxyboetirane A
(8R)-8-Hydroxyepoxyboetirane A is a neuroactivating compound that interacts with PKCδ-C1B. This compound binds into the PKC enzyme pocket through hydrogen bonds with glycine-253, leucine-251, and threonine-242. It induces the release of NRG1 and promotes the differentiation of neural stem cells into neurons. (8R)-8-Hydroxyepoxyboetirane A holds potential for research into nervous system disorders.Color and Shape:Odour Solid20-HETE
CAS:20-HETE is a CYP450 product, vasoconstrictor, modulates K+ channels, affects NADPH, ROS, NF-κB, NO synthase, and cell apoptosis/proliferation.Formula:C20H32O3Purity:99.79%Color and Shape:SolidMolecular weight:320.47Ref: TM-T14021
1mg (312.04μM*10mL in Ethanol)1,139.00€5mg (312.04μM*50mL in Ethanol)2,327.00€100μg (312.04μM*1mL in Ethanol)474.00€PKCiota-IN-2
CAS:PKCiota-IN-2 selectively inhibits PKC-ι (IC50=2.8nM) and also blocks PKC-α, ε (IC50s=71nM, 350nM).Formula:C24H21N5OPurity:99.74%Color and Shape:SolidMolecular weight:395.46Ref: TM-T9863
1mg115.00€2mg172.00€5mg255.00€10mg375.00€25mg562.00€50mg792.00€100mg1,064.00€1mL*10mM (DMSO)279.00€
