Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Products of "Chromatin/Epigenetics"
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ARV-825
CAS:ARV-825: PROTAC recruits BRD4 to cereblon for rapid BRD4 degradation in all tested BL cells.Formula:C46H47ClN8O9SPurity:97.15% - 98%Color and Shape:SolidMolecular weight:923.43BIX-01294 trihydrochloride
CAS:BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.Formula:C28H38N6O2·3HClPurity:99.41% - 99.95%Color and Shape:SolidMolecular weight:600.02Ref: TM-T1959
1mg44.00€2mg55.00€5mg71.00€10mg107.00€25mg192.00€50mg274.00€100mg492.00€500mg1,103.00€1mL*10mM (DMSO)139.00€Eleven-Nineteen-Leukemia Protein IN-3
CAS:ENL YEATS inhibitor Eleven-Nineteen-Leukemia Protein IN-3, IC50 15.4 nM, orally active, suppresses MYC, stabilizes ENL in vitro.Formula:C28H27N5O2Purity:98%Color and Shape:SolidMolecular weight:465.55WIKI4
CAS:WIKI4 is a potent inhibitor of Wnt/β-catenin signaling and tankyrase 2 (TNKS2).Formula:C29H23N5O3SPurity:99.32% - 99.6%Color and Shape:SolidMolecular weight:521.59Tozasertib
CAS:Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).Formula:C23H28N8OSPurity:99.99%Color and Shape:SolidMolecular weight:464.59XD14
CAS:XD14 inhibits BET bromodomains with Kd: BRD4(1) 160nM, BRD2(1) 170nM, BRD3(1) 380nM, BRD3(2) 490nM, BRD2(2) 830nM, BRD4(2) 850nM.Formula:C20H27N3O5SPurity:98.4%Color and Shape:SolidMolecular weight:421.51GSK-J4 Hydrochloride
CAS:GSK-J4 Hydrochloride (GSK J4 HCl) is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. It is an ethyl ester derivative of the GSK-J1.Formula:C24H28ClN5O2Purity:97.95% - 98.23%Color and Shape:SolidMolecular weight:453.97Ref: TM-T4383
1mg40.00€2mg52.00€5mg88.00€10mg127.00€25mg217.00€50mg363.00€100mg533.00€200mg745.00€1mL*10mM (DMSO)139.00€Amodiaquine dihydrochloride dihydrate
CAS:Amodiaquine dihydrochloride dihydrate (Amodiaquin hydrochloride) is an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory effectsFormula:C20H28Cl3N3O3Purity:99.97%Color and Shape:SolidMolecular weight:464.82ZEN-3219
CAS:ZEN-3219 is a BET inhibitor, which has inhibitory effect on BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2).Formula:C19H18N2O3Purity:99.06%Color and Shape:SolidMolecular weight:322.36NVP-TNKS656
CAS:NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.Formula:C27H34N4O5Purity:99.59%Color and Shape:SolidMolecular weight:494.58Ref: TM-T3261
1mg46.00€2mg57.00€5mg88.00€10mg129.00€25mg261.00€50mg444.00€100mg652.00€1mL*10mM (DMSO)87.00€Ethyl 3,4-dihydroxybenzoate
CAS:Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.Formula:C9H10O4Purity:99.88%Color and Shape:White Crystal Or PowderMolecular weight:182.17JQ-1 (carboxylic acid)
CAS:JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)Formula:C19H17ClN4O2SPurity:99.14% - 99.9%Color and Shape:SolidMolecular weight:400.88Aurora B inhibitor 1
CAS:Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor (Ki <0.010 uM) with potential anticancer activity for cancer research.Formula:C25H26ClF2N7O2Purity:98.37%Color and Shape:SolidMolecular weight:529.97TY-011
CAS:TY-011 is an inhibitor of Aurora A/B kinases. This compound induces DNA damage and cell apoptosis (Apoptosis) in human gastric cancer cells by promoting abnormal microtubule-kinetochore attachments, effectively suppressing cancer cell proliferation. The IC50 values for TY-011 in human gastric cancer cell lines range from 0.11-4.49 μM. It is utilized in research focused on gastric cancer.Formula:C18H16ClN5Color and Shape:SolidMolecular weight:337.81Tetrahydrouridine
CAS:Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator.Formula:C9H16N2O6Purity:98%Color and Shape:SolidMolecular weight:248.23GSK9311
CAS:GSK9311 inhibits BRPF bromodomain (pIC50: 6.0 and 4.3 for BRPF1 and BRPF2, respectively).Formula:C24H31N5O3Purity:98%Color and Shape:SolidMolecular weight:437.53PRMT4-IN-3
PRMT4-IN-3 (compound 56) serves as a potent class I protein arginine methyltransferase (PRMT) inhibitor, specifically targeting PRMT4 with an IC50 value of 37Formula:C23H29N7OPurity:98%Color and Shape:SolidMolecular weight:419.52Jaspamycin
CAS:Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα.Formula:C12H12N4O5Color and Shape:SolidMolecular weight:292.25FD1024
CAS:FD1024 is a potent PIM inhibitor, displaying inhibitory concentrations (IC50s) of 1.96 nM, 38.9 nM, and 4.17 nM for PIM1, PIM2, and PIM3, respectively.Formula:C21H20F2N4O2SPurity:98%Color and Shape:SolidMolecular weight:430.47Ginsenoside Rk1
CAS:Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.Formula:C42H70O12Purity:99.13%Color and Shape:SolidMolecular weight:767GSK126
CAS:GSK126 (GSK2816126A) is a excellently specific EZH2 methyltransferase inhibitor ( IC50=9.9 nM).Formula:C31H38N6O2Purity:98% - 99.67%Color and Shape:SolidMolecular weight:526.67Ref: TM-T2079
2mg44.00€5mg65.00€10mg88.00€25mg152.00€50mg227.00€100mg349.00€200mg455.00€1mL*10mM (DMSO)74.00€SMYD2-IN-1
CAS:SMYD2-IN-1 is an inhibitor of SMYD2 (IC50 of 4.45 nM).Formula:C25H25Cl2F2N7O2Purity:98%Color and Shape:SolidMolecular weight:564.41AT9283
CAS:AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).Formula:C19H23N7O2Purity:99.83% - 99.98%Color and Shape:SolidMolecular weight:381.43Ref: TM-T3068
1mg47.00€2mg60.00€5mg95.00€10mg170.00€25mg299.00€50mg499.00€100mg723.00€1mL*10mM (DMSO)97.00€CCT241736
CAS:CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3Formula:C22H23Cl2N7Purity:96.2% - 99.88%Color and Shape:SolidMolecular weight:456.37IHMT-EZH2-426
IHMT-EZH2-426 (compound 38) is a potent, covalent degrader of EZH2, demonstrating IC50 values of 1.3 nM for EZH2 wild-type, 1.2 nM for EZH2-A687V, and 1.7-3.5Formula:C31H35FN4O4SPurity:98%Color and Shape:SolidMolecular weight:578.7MS9715
MS9715 is a potent and selective NSD3-targeting PROTAC, designed by leveraging BI-9321, which targets the PWWP1 domain of NSD3, in conjunction with an E3 ligaseFormula:C58H74FN9O5SPurity:98%Color and Shape:SolidMolecular weight:1028.33GSK467
CAS:GSK467 is a potent and selective inhibitor of KDM5 (JARID1)(Ki : 10 nM).Formula:C17H13N5O2Purity:99.55%Color and Shape:SolidMolecular weight:319.32Pacritinib
CAS:Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).Formula:C28H32N4O3Purity:99.25% - 99.49%Color and Shape:SolidMolecular weight:472.58GSK778 hydrochloride
CAS:GSK778 hydrochloride is a selective BET BD1 bromodomain inhibitor, with IC50s ranging from 41 to 143 nM, effective in cancer models.Formula:C30H34ClN5O3Purity:97.45%Color and Shape:SolidMolecular weight:548.08Ref: TM-T9703L
1mg115.00€5mg249.00€10mg368.00€25mg562.00€50mg787.00€100mg1,054.00€1mL*10mM (DMSO)319.00€PBRM1-BD2-IN-7
CAS:PBRM1-BD2-IN-7, a PBRM1 bromodomain inhibitor with an IC50 of 0.29 μM, is used in cancer research.Formula:C16H15ClN2OPurity:99% - 99.86%Color and Shape:SoildMolecular weight:286.76Ref: TM-T60155
1mg115.00€5mg255.00€10mg375.00€25mg562.00€50mg792.00€100mg1,064.00€500mg2,147.00€1mL*10mM (DMSO)240.00€Upadacitinib
CAS:Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.Formula:C17H19F3N6OPurity:98.96% - 99.93%Color and Shape:SolidMolecular weight:380.37Ref: TM-T7503
1mg47.00€2mg62.00€5mg89.00€10mg130.00€25mg220.00€50mg306.00€100mg434.00€200mg662.00€500mg1,169.00€1mL*10mM (DMSO)48.00€BRD7-IN-1
CAS:BRD7-IN-1, a BI7273 derivative, forms PROTAC VZ185, targeting BRD7/9 with DC50s of 4.5/1.8 nM via VHL ligand linkage.Formula:C22H28Cl2N4O3Purity:98.95%Color and Shape:SolidMolecular weight:467.39OXF BD 02
CAS:OXF BD 02 is a potent and selective BRD4(1) inhibitor (IC50: 382 nM) with anticancer and anti-inflammatory activity.Formula:C18H17NO3Purity:98.25%Color and Shape:SolidMolecular weight:295.33LSD1-IN-24
CAS:LSD1-IN-24 is a selective and potent LSD1 inhibitor with an IC50 value of 0.247 μM.LSD1-IN-24 induces PD-L1 expression and enhances the T cell killing responseFormula:C18H20N2OSPurity:99.53%Color and Shape:SoildMolecular weight:312.43Ref: TM-T67871
1mg57.00€5mg120.00€10mg187.00€25mg374.00€50mg612.00€100mg938.00€500mg1,882.00€1mL*10mM (DMSO)133.00€BRD0639
CAS:BRD0639 is a first-in-class PRMT5-substrate interaction inhibitor for PBM-dependent PRMT5 activity studies.Formula:C21H22ClN5O4SPurity:99.85%Color and Shape:SolidMolecular weight:475.95EEDi-5285
CAS:EEDi-5285: potent EED inhibitor, orally active, IC50=0.2nM, targets EED protein, anti-cancer properties.Formula:C24H22FN5O3SPurity:100%Color and Shape:SolidMolecular weight:479.53(+)-JQ1 PA
CAS:(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1(IC50 of 10.4 nM).Formula:C22H20ClN5OSPurity:98.36%Color and Shape:SolidMolecular weight:437.95Desidustat
CAS:Desidustat is an inhibitor of HIF hydroxylase.Formula:C16H16N2O6Purity:98%Color and Shape:SolidMolecular weight:332.31Ref: TM-T5176
1mg35.00€2mg52.00€5mg94.00€10mg167.00€25mg300.00€50mg516.00€100mg732.00€1ml*10 (DMSO)112.00€Histone Acetyltransferase Inhibitor II
CAS:Histone Acetyltransferase Inhibitor II is a selective and cell permeable inhibitor of p300 histone acetyltransferase(IC50 : 5 μM).with anti-acetylase activityFormula:C20H16Br2O3Purity:97.13%Color and Shape:SolidMolecular weight:464.15(R)-(-)-JQ1 Enantiomer
CAS:(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on BRD4(1/2)(IC50 of 77 nM/33 nM in a cell-free assay)Formula:C23H25ClN4O2SPurity:99.38%Color and Shape:SolidMolecular weight:456.99MZ 1
CAS:MZ 1 is a BRD4 protein degrader based on PROTAC technology.Formula:C49H60ClN9O8S2Purity:99.31%Color and Shape:SolidMolecular weight:1002.64Gandotinib
CAS:LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).Formula:C23H25ClFN7OPurity:99.33% - 99.86%Color and Shape:SolidMolecular weight:469.94Ref: TM-T2638
5mg51.00€10mg88.00€25mg160.00€50mg296.00€100mg469.00€500mg1,035.00€1mL*10mM (DMSO)57.00€JAK2-IN-7
CAS:JAK2-IN-7 selectively inhibits JAK2 (IC50: 3 nM), shows 14-fold selectivity over JAK1/3, FLT3, induces G0/G1 arrest, apoptosis, and has antitumor effects.Formula:C26H33N7OPurity:98.71%Color and Shape:SolidMolecular weight:459.59Ref: TM-T35900
1mg145.00€5mg354.00€10mg630.00€25mg1,301.00€50mg1,738.00€100mg2,357.00€1mL*10mM (DMSO)358.00€AZ-3
CAS:AZ-3 is a potent and selective JAK1 inhibitor (IC50: 34 nM).Formula:C20H28FN7Purity:98%Color and Shape:SolidMolecular weight:385.48JAK-IN-28
CAS:JAK-IN-28 (Compound 111) is a Janus kinase (JAK) inhibitor potentially applicable in the research of cancer and inflammatory diseases [1].Formula:C20H18ClN7OPurity:98%Color and Shape:SolidMolecular weight:407.86AMI-1
CAS:AMI-1 is an effective and selective Histone Methyltransferase (HMT) inhibitor (IC50: 3.0/8.8 μM, for yeast Hmt1p, and human PRMT1).Formula:C21H14N2Na2O9S2Purity:97.53% - 99.9%Color and Shape:DrypowderMolecular weight:548.45Eicosapentaenoic Acid
CAS:Eicosapentaenoic Acid (EPA) is a ω-3 fatty acid abundantly available in marine organisms.Formula:C20H30O2Purity:96.20%Color and Shape:LiquidMolecular weight:302.45Menin-MLL inhibitor MI-2
CAS:Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.Formula:C18H25N5S2Purity:97.46%Color and Shape:SolidMolecular weight:375.55Ref: TM-T2649
2mg42.00€5mg62.00€10mg88.00€25mg169.00€50mg243.00€100mg376.00€200mg550.00€1mL*10mM (DMSO)67.00€MS436
CAS:MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.Formula:C18H17N5O3SPurity:97.95% - 98.92%Color and Shape:SolidMolecular weight:383.42Ref: TM-T1854
2mg44.00€5mg65.00€10mg103.00€25mg192.00€50mg344.00€100mg505.00€500mg1,093.00€1mL*10mM (DMSO)72.00€MBM-17S
CAS:MBM-17S, a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM, effectively inhibits cancer cell proliferation by inducing cell cycle arrest andFormula:C36H40N6O10Purity:98%Color and Shape:SolidMolecular weight:716.74SF2523
CAS:SF2523 is a highly selective and potent inhibitor.Formula:C19H17NO5SPurity:97.78% - 98.06%Color and Shape:SolidMolecular weight:371.41Ref: TM-T3986
1mg37.00€5mg79.00€10mg119.00€25mg274.00€50mg432.00€100mg638.00€500mg1,359.00€1mL*10mM (DMSO)87.00€MI-2-2
CAS:MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.Formula:C17H20F3N5S2Purity:99.56%Color and Shape:SolidMolecular weight:415.5BCI-121
CAS:BCI-121 is a substrate-competitive SMYD3 inhibitor that inhibits the proliferation of the cancer cell.Formula:C14H18BrN3O2Purity:99.67%Color and Shape:SolidMolecular weight:340.22Belzutifan
CAS:"Belzutifan (MK-6482) is an oral HIF-2α inhibitor for ccRCC, with enhanced potency (IC50: 9 nM)."Formula:C17H12F3NO4SPurity:99.34% - 99.41%Color and Shape:SolidMolecular weight:383.34Ref: TM-T16679
1mg70.00€5mg153.00€10mg216.00€25mg411.00€50mg660.00€100mg938.00€200mg1,264.00€1mL*10mM (DMSO)166.00€ACBI1
CAS:ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50sFormula:C49H58FN9O7SPurity:97.54% - 98.15%Color and Shape:SolidMolecular weight:936.1SCH-1473759 hydrochloride
CAS:SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).Formula:C20H27ClN8OSPurity:98.29%Color and Shape:SolidMolecular weight:463Niraparib tosylate monohyrate
CAS:Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.Formula:C26H30N4O5SPurity:99.09%Color and Shape:SolidMolecular weight:510.61Ref: TM-T9497
5mg60.00€10mg87.00€25mg117.00€50mg144.00€100mg216.00€200mg325.00€500mg545.00€1mL*10mM (DMSO)77.00€HIF-2α agonist 2
CAS:HIF-2α agonist 2 is an HIF-2α agonist with an EC50 value of 1.68 μM for HIF-2α.Formula:C13H8Br2N2O2SPurity:98.32%Color and Shape:SoildMolecular weight:416.09NCD38 TFA
NCD38 TFA serves as a selective inhibitor of LSD1 [1] [2].Formula:C37H37ClF3N3O4Purity:98%Color and Shape:SolidMolecular weight:680.16L002
CAS:L002 is a potent inhibitor of acetyltransferase p300 with an IC50 of 1.98 μM, blocking histone and p53 acetylation, and may treat cardiac hypertrophy.Formula:C15H15NO5SPurity:98.59%Color and Shape:SolidMolecular weight:321.35UNC0642
CAS:UNC0642 is an effective and specific G9a/GLP inhibitor (IC50< 2.5 nM).Formula:C29H44F2N6O2Purity:98.75% - 99.5%Color and Shape:SolidMolecular weight:546.7Ref: TM-T4166
1mg40.00€2mg52.00€5mg87.00€10mg131.00€25mg230.00€50mg378.00€100mg567.00€200mg825.00€1mL*10mM (DMSO)95.00€Amodiaquine
CAS:Amodiaquine is a synthetic aminoquinoline, used to treat malaria.Formula:C20H22ClN3OPurity:99.78%Color and Shape:Crystals From Absolute Ethanol SolidMolecular weight:355.86Ref: TM-T8381
1mg52.00€2mg70.00€5mg96.00€10mg173.00€25mg304.00€50mg452.00€100mg647.00€1mL*10mM (DMSO)120.00€DDO-3055
CAS:DDO-3055 is an orally active PHD2 inhibitor utilized in studies related to anemia associated with chronic kidney disease.Formula:C17H13ClN2O5Color and Shape:SolidMolecular weight:360.749BI-847325
CAS:BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.Formula:C29H28N4O2Purity:97.13% - 97.54%Color and Shape:SolidMolecular weight:464.56Ref: TM-T6785
1mg49.00€5mg97.00€10mg153.00€25mg296.00€50mg445.00€100mg660.00€200mg917.00€1mL*10mM (DMSO)97.00€Pumecitinib
CAS:Pumecitinib is a Janus kinase (JAK) inhibitor. Pumecitinib exhibits anti-inflammatory activity.Formula:C17H20N8O2SPurity:99.89%Color and Shape:SoildMolecular weight:400.46LP99
CAS:LP99 is an epigenetic probe.Formula:C26H30ClN3O4SPurity:98.74%Color and Shape:SolidMolecular weight:516.05Ref: TM-T15784
1mg43.00€5mg96.00€10mg145.00€25mg305.00€50mg442.00€100mgTo inquire1mL*10mM (DMSO)97.00€SJ46421
SJ46421, a PROTAC protein degrader derived from (+)-JQ-1, targets KLHDC2. It efficiently forms a stable ternary complex with KLHDC2, exhibiting an IC50 of 7.8 nM. Furthermore, SJ46421 promotes the polyubiquitination of the BD2 domain of BRD2, BRD3, or BRD4.Formula:C42H41ClN8O5S2Color and Shape:SolidMolecular weight:837.41LSD1-IN-6
CAS:LSD1-IN-6, a potent LSD1 inhibitor (IC50: 123 nM), enhances H3K4me2 without altering LSD1 expression. Reversible.Formula:C15H13BrN2O3Purity:98%Color and Shape:SolidMolecular weight:349.18JW 55
CAS:JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2Formula:C25H26N2O5Purity:99.31% - 99.76%Color and Shape:SolidMolecular weight:434.48LSD1-IN-38
LSD1-IN-38 (Compound 23e) is a reversible, orally active inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 1.2 nM. It effectively inhibits the proliferation of cancer cells MV4-11, Kasumi-1, and NCI-H526 with IC50 values of 5, 4, and 11 nM, respectively. Furthermore, LSD1-IN-38 activates CD86 expression with an EC50 of 0.034 μM and induces differentiation in MV4-11 cells. In mouse models, this compound demonstrates antitumor activity.Formula:C30H29F4N5Molecular weight:535.578BRD4770
CAS:BRD4770 is a histone methyltransferase G9a inhibitor and induces cell senescence.Formula:C25H23N3O3Purity:99.82%Color and Shape:SolidMolecular weight:413.47XY1
CAS:XY1 is a very close analogue of SGC707 (a potent, selective, and non-competitive inhibitor of PRMT3 with IC50 of 31 nM), It is intended to be used as aFormula:C17H19N3O2Purity:97.2% - 97.74%Color and Shape:SolidMolecular weight:297.35E7016
CAS:E7016 (GPI 21016) is an orally available PARP inhibitor. E7016 inhibits of DNA repair. E7016 can enhance tumor cell radiosensitivity in vitro and in vivo.Formula:C20H19N3O3Purity:98.16%Color and Shape:SolidMolecular weight:349.38Fosifidancitinib
CAS:Fosifidancitinib is a potent inhibitor of JAK 1 and JAK 3.Formula:C21H21FN5O7PPurity:99.55%Color and Shape:SolidMolecular weight:505.39Ref: TM-T38624
1mg87.00€2mg124.00€5mg187.00€10mg284.00€25mg452.00€50mg645.00€100mg867.00€200mg1,159.00€PROTAC BRD3/BRD4-L degrader-2
PROTAC BRD3/BRD4-L degrader-2, a PROTAC molecule, selectively degrades cellular BRD3 and BRD4-L with K i values of 16.91 and 2.8 nM, respectively, and exhibitsFormula:C43H44ClN7O3Purity:98%Color and Shape:SolidMolecular weight:742.31STAT3-IN-18
CAS:STAT3-IN-18 (compound SPP), a platinum (IV) complex featuring an axial ligand from sandalwood, suppresses the JAK2-STAT3 pathway in breast cancer (BC) cells andFormula:C18H24Cl2N2O6PtPurity:98%Color and Shape:SolidMolecular weight:630.38UNC0321
CAS:UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.Formula:C27H45N7O3Purity:99.25%Color and Shape:SolidMolecular weight:515.69GXF-111
GXF-111, a proteolysis targeting chimera (PROTAC) molecule, efficiently induces the selective degradation of the BRD3 and BRD4-L proteins.Formula:C42H42ClN7O3Purity:98%Color and Shape:SolidMolecular weight:728.28JAK1-IN-8
CAS:JAK1-IN-8, a specific inhibitor of Janus kinase 1 (JAK1, IC50<500 nM).Formula:C22H23FN4O3SPurity:98.36%Color and Shape:SolidMolecular weight:442.51Ref: TM-T35899
5mg47.00€10mg79.00€25mg144.00€50mg250.00€100mg424.00€200mg568.00€1mL*10mM (DMSO)50.00€MI-136
CAS:MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced.Formula:C23H21F3N6SPurity:97.08% - 98.63%Color and Shape:SolidMolecular weight:470.51Ref: TM-T6889
1mg47.00€5mg87.00€10mg147.00€25mg279.00€50mg472.00€100mg730.00€200mg1,017.00€1mL*10mM (DMSO)97.00€BETd-260
CAS:BETd-260, a PROTAC linked by a Cereblon ligand and a BET ligand, has an inhibitory effect on BRD4 protein in leukemic cell lines.Formula:C43H46N10O6Purity:96.76%Color and Shape:SolidMolecular weight:798.89AU-15330
CAS:AU-15330 is a proteolytic targeting chimera (PROTAC) that simultaneously targets SMARCA4, SMARCA2, and PBRM1 for degradation and exhibits cytotoxicity in H3.3K27M cells but not in H3 wild-type cells. Cost-effective and quality-assured.Formula:C39H49N9O5SPurity:100% - 98.21%Color and Shape:SolidMolecular weight:755.93Albendazole
CAS:Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.Formula:C12H15N3O2SPurity:98.21% - 98.76%Color and Shape:Colorless Crystals SolidMolecular weight:265.33CPI-169 racemate
CAS:CPI-169 racemate (CPI 169) is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.Formula:C27H36N4O5SPurity:99.59%Color and Shape:SolidMolecular weight:528.66Ref: TM-T6809
1mg56.00€2mg79.00€5mg125.00€10mg172.00€25mg376.00€50mg560.00€100mg797.00€1mL*10mM (DMSO)145.00€S-Ruxolitinib
CAS:S-Ruxolitinib can be used in related research in the field of life sciences. Its product number is T3066 and CAS number is 1160597-27-2.Formula:C17H18N6Purity:98%Color and Shape:SolidMolecular weight:306.37MAT2A inhibitor 2
CAS:MAT2A inhibitor 2 is an inhibitor of methionine adenosyltransferase 2A (MAT2A).Formula:C18H24ClN3O3Purity:99.52%Color and Shape:SolidMolecular weight:365.85Ref: TM-T11950
1mg51.00€5mg106.00€10mg169.00€25mg298.00€50mg445.00€100mg655.00€500mg1,359.00€1mL*10mM (DMSO)119.00€Venadaparib
CAS:Venadaparib, a PARP inhibitor (IC50: 1.4/1.0 nM for PARP1/2), is orally active, selective, not affecting PARP-5, used in tumor studies.Formula:C23H23FN4O2Purity:98.47%Color and Shape:SolidMolecular weight:406.45Ref: TM-T9430
1mg48.00€2mg63.00€5mg96.00€10mg144.00€25mg283.00€50mg464.00€100mg680.00€1mL*10mM (DMSO)96.00€PROTAC BRD9 Degrader-6
CAS:PROTAC BRD9 Degrader-6, with an IC50 value of 0.13 nM, is a potent degrader of BRD9 suitable for research on BAF complex-related disorders [1].Formula:C47H56N8O6Purity:98%Color and Shape:SolidMolecular weight:829(Rac)-BAY1238097
CAS:(Rac)-BAY1238097 is a inhibitor of BET(IC50 of 1.02 μM for BRD4),used in cancer research.Formula:C25H33N5O3Purity:98%Color and Shape:SolidMolecular weight:451.56MS023 dihydrochloride
CAS:MS023 dihydrochloride (MS023 2HCl) is a human type I protein arginine methyltransferase inhibitor with antitumour activity for the study of breast cancer.Formula:C17H27Cl2N3OPurity:99.52%Color and Shape:SolidMolecular weight:360.32LNK01004
CAS:LNK01004 is a JAK inhibitor that exhibits potent inhibitory effects on JAK1 (IC50: 10 nM), JAK2 (IC50: ＜0.51 nM), and TYK2 (IC50: 1.0 nM). It can concurrently inhibit multiple cytokine-induced p-STAT signaling pathways and is applicable for research on diseases such as atopic dermatitis.Formula:C26H31N7O2Color and Shape:SolidMolecular weight:473.57Londamocitinib
CAS:Londamocitinib (JAK1-IN-7) is a selective and potent JAK1 inhibitor with anti-inflammatory activity.Formula:C28H31F2N7O4SPurity:99.47%Color and Shape:SolidMolecular weight:599.65Ref: TM-T11706
1mg180.00€5mg439.00€10mg597.00€25mg905.00€50mg1,169.00€100mg1,568.00€1mL*10mM (DMSO)567.00€IDF-11774
CAS:IDF-11774 is a HIF-1 inhibitor.It reduces hif-1α HRE luciferase activity (IC50 = 3.65 μM).Formula:C23H32N2O2Purity:98.05%Color and Shape:SolidMolecular weight:368.51PFI-2
CAS:PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over otherFormula:C23H25F4N3O3SPurity:99.38%Color and Shape:SolidMolecular weight:499.52Methylstat
CAS:Methylstat is a methyl ester prodrug of a Jumonji C domain-containing histone demethylase (JMJD) inhibitor that has favorable cell permeability.Formula:C28H31N3O6Purity:98.34% - 98.34%Color and Shape:SolidMolecular weight:505.56NU 9056
CAS:NU 9056 is an effective and selective inhibitor of KAT5 histone acetyltransferase with an IC50 of 2 µM.Formula:C6H4N2S4Purity:95.36%Color and Shape:SolidMolecular weight:232.37Gentiakochianin
CAS:Gentiakochianin (Swertianine), vasodilatory, induce G(2)/M phase and inhibits proliferation, reduces oxLDL-induced , inhibits ROS s,up-regulated Akt/CREB/eNOS.Formula:C14H10O6Purity:98.97%Color and Shape:SolidMolecular weight:274.23E-7386
CAS:E-7386 is an oral active CBP/ -catenin modulator.Formula:C39H48FN9O4Purity:98.92% - 99%Color and Shape:SolidMolecular weight:725.85Ref: TM-T11136
1mg87.00€5mg255.00€10mg376.00€25mg647.00€50mg920.00€100mg1,225.00€1mL*10mM (DMSO)399.00€MLN8054
CAS:MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.Formula:C25H15ClF2N4O2Purity:98.07% - 98.26%Color and Shape:SolidMolecular weight:476.86Ref: TM-T6315
1mg52.00€2mg71.00€5mg88.00€10mg127.00€25mg233.00€50mg376.00€100mg567.00€1mL*10mM (DMSO)93.00€CPI-637
CAS:CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor.Formula:C22H22N6OPurity:99.75% - 99.91%Color and Shape:SolidMolecular weight:386.45
