Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Products of "Chromatin/Epigenetics"
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ARV-825
CAS:ARV-825: PROTAC recruits BRD4 to cereblon for rapid BRD4 degradation in all tested BL cells.Formula:C46H47ClN8O9SPurity:97.15% - 98%Color and Shape:SolidMolecular weight:923.43BIX-01294 trihydrochloride
CAS:BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.Formula:C28H38N6O2·3HClPurity:99.41% - 99.95%Color and Shape:SolidMolecular weight:600.02Ref: TM-T1959
1mg44.00€2mg55.00€5mg71.00€10mg107.00€25mg192.00€50mg274.00€100mg492.00€500mg1,103.00€1mL*10mM (DMSO)139.00€Eleven-Nineteen-Leukemia Protein IN-3
CAS:ENL YEATS inhibitor Eleven-Nineteen-Leukemia Protein IN-3, IC50 15.4 nM, orally active, suppresses MYC, stabilizes ENL in vitro.Formula:C28H27N5O2Purity:98%Color and Shape:SolidMolecular weight:465.55WIKI4
CAS:WIKI4 is a potent inhibitor of Wnt/β-catenin signaling and tankyrase 2 (TNKS2).Formula:C29H23N5O3SPurity:99.32% - 99.6%Color and Shape:SolidMolecular weight:521.59Tozasertib
CAS:Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).Formula:C23H28N8OSPurity:99.99%Color and Shape:SolidMolecular weight:464.59XD14
CAS:XD14 inhibits BET bromodomains with Kd: BRD4(1) 160nM, BRD2(1) 170nM, BRD3(1) 380nM, BRD3(2) 490nM, BRD2(2) 830nM, BRD4(2) 850nM.Formula:C20H27N3O5SPurity:98.4%Color and Shape:SolidMolecular weight:421.51GSK-J4 Hydrochloride
CAS:GSK-J4 Hydrochloride (GSK J4 HCl) is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. It is an ethyl ester derivative of the GSK-J1.Formula:C24H28ClN5O2Purity:97.95% - 98.23%Color and Shape:SolidMolecular weight:453.97Ref: TM-T4383
1mg40.00€2mg52.00€5mg88.00€10mg127.00€25mg217.00€50mg363.00€100mg533.00€200mg745.00€1mL*10mM (DMSO)139.00€Amodiaquine dihydrochloride dihydrate
CAS:Amodiaquine dihydrochloride dihydrate (Amodiaquin hydrochloride) is an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory effectsFormula:C20H28Cl3N3O3Purity:99.97%Color and Shape:SolidMolecular weight:464.82ZEN-3219
CAS:ZEN-3219 is a BET inhibitor, which has inhibitory effect on BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2).Formula:C19H18N2O3Purity:99.06%Color and Shape:SolidMolecular weight:322.36NVP-TNKS656
CAS:NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.Formula:C27H34N4O5Purity:99.59%Color and Shape:SolidMolecular weight:494.58Ref: TM-T3261
1mg46.00€2mg57.00€5mg88.00€10mg129.00€25mg261.00€50mg444.00€100mg652.00€1mL*10mM (DMSO)87.00€Ethyl 3,4-dihydroxybenzoate
CAS:Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.Formula:C9H10O4Purity:99.88%Color and Shape:White Crystal Or PowderMolecular weight:182.17JQ-1 (carboxylic acid)
CAS:JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)Formula:C19H17ClN4O2SPurity:99.14% - 99.9%Color and Shape:SolidMolecular weight:400.88Aurora B inhibitor 1
CAS:Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor (Ki <0.010 uM) with potential anticancer activity for cancer research.Formula:C25H26ClF2N7O2Purity:98.37%Color and Shape:SolidMolecular weight:529.97TY-011
CAS:TY-011 is an inhibitor of Aurora A/B kinases. This compound induces DNA damage and cell apoptosis (Apoptosis) in human gastric cancer cells by promoting abnormal microtubule-kinetochore attachments, effectively suppressing cancer cell proliferation. The IC50 values for TY-011 in human gastric cancer cell lines range from 0.11-4.49 μM. It is utilized in research focused on gastric cancer.Formula:C18H16ClN5Color and Shape:SolidMolecular weight:337.81Tetrahydrouridine
CAS:Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator.Formula:C9H16N2O6Purity:98%Color and Shape:SolidMolecular weight:248.23GSK9311
CAS:GSK9311 inhibits BRPF bromodomain (pIC50: 6.0 and 4.3 for BRPF1 and BRPF2, respectively).Formula:C24H31N5O3Purity:98%Color and Shape:SolidMolecular weight:437.53PRMT4-IN-3
PRMT4-IN-3 (compound 56) serves as a potent class I protein arginine methyltransferase (PRMT) inhibitor, specifically targeting PRMT4 with an IC50 value of 37Formula:C23H29N7OPurity:98%Color and Shape:SolidMolecular weight:419.52Jaspamycin
CAS:Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα.Formula:C12H12N4O5Color and Shape:SolidMolecular weight:292.25FD1024
CAS:FD1024 is a potent PIM inhibitor, displaying inhibitory concentrations (IC50s) of 1.96 nM, 38.9 nM, and 4.17 nM for PIM1, PIM2, and PIM3, respectively.Formula:C21H20F2N4O2SPurity:98%Color and Shape:SolidMolecular weight:430.47Ginsenoside Rk1
CAS:Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.Formula:C42H70O12Purity:99.13%Color and Shape:SolidMolecular weight:767GSK126
CAS:GSK126 (GSK2816126A) is a excellently specific EZH2 methyltransferase inhibitor ( IC50=9.9 nM).Formula:C31H38N6O2Purity:98% - 99.67%Color and Shape:SolidMolecular weight:526.67Ref: TM-T2079
2mg44.00€5mg65.00€10mg88.00€25mg152.00€50mg227.00€100mg349.00€200mg455.00€1mL*10mM (DMSO)74.00€SMYD2-IN-1
CAS:SMYD2-IN-1 is an inhibitor of SMYD2 (IC50 of 4.45 nM).Formula:C25H25Cl2F2N7O2Purity:98%Color and Shape:SolidMolecular weight:564.41AT9283
CAS:AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).Formula:C19H23N7O2Purity:99.83% - 99.98%Color and Shape:SolidMolecular weight:381.43Ref: TM-T3068
1mg47.00€2mg60.00€5mg95.00€10mg170.00€25mg299.00€50mg499.00€100mg723.00€1mL*10mM (DMSO)97.00€CCT241736
CAS:CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3Formula:C22H23Cl2N7Purity:96.2% - 99.88%Color and Shape:SolidMolecular weight:456.37IHMT-EZH2-426
IHMT-EZH2-426 (compound 38) is a potent, covalent degrader of EZH2, demonstrating IC50 values of 1.3 nM for EZH2 wild-type, 1.2 nM for EZH2-A687V, and 1.7-3.5Formula:C31H35FN4O4SPurity:98%Color and Shape:SolidMolecular weight:578.7MS9715
MS9715 is a potent and selective NSD3-targeting PROTAC, designed by leveraging BI-9321, which targets the PWWP1 domain of NSD3, in conjunction with an E3 ligaseFormula:C58H74FN9O5SPurity:98%Color and Shape:SolidMolecular weight:1028.33GSK467
CAS:GSK467 is a potent and selective inhibitor of KDM5 (JARID1)(Ki : 10 nM).Formula:C17H13N5O2Purity:99.55%Color and Shape:SolidMolecular weight:319.32Pacritinib
CAS:Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).Formula:C28H32N4O3Purity:99.25% - 99.49%Color and Shape:SolidMolecular weight:472.58GSK778 hydrochloride
CAS:GSK778 hydrochloride is a selective BET BD1 bromodomain inhibitor, with IC50s ranging from 41 to 143 nM, effective in cancer models.Formula:C30H34ClN5O3Purity:97.45%Color and Shape:SolidMolecular weight:548.08Ref: TM-T9703L
1mg115.00€5mg249.00€10mg368.00€25mg562.00€50mg787.00€100mg1,054.00€1mL*10mM (DMSO)319.00€PBRM1-BD2-IN-7
CAS:PBRM1-BD2-IN-7, a PBRM1 bromodomain inhibitor with an IC50 of 0.29 μM, is used in cancer research.Formula:C16H15ClN2OPurity:99% - 99.86%Color and Shape:SoildMolecular weight:286.76Ref: TM-T60155
1mg115.00€5mg255.00€10mg375.00€25mg562.00€50mg792.00€100mg1,064.00€500mg2,147.00€1mL*10mM (DMSO)240.00€Upadacitinib
CAS:Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.Formula:C17H19F3N6OPurity:98.96% - 99.93%Color and Shape:SolidMolecular weight:380.37Ref: TM-T7503
1mg47.00€2mg62.00€5mg89.00€10mg130.00€25mg220.00€50mg306.00€100mg434.00€200mg662.00€500mg1,169.00€1mL*10mM (DMSO)48.00€BRD7-IN-1
CAS:BRD7-IN-1, a BI7273 derivative, forms PROTAC VZ185, targeting BRD7/9 with DC50s of 4.5/1.8 nM via VHL ligand linkage.Formula:C22H28Cl2N4O3Purity:98.95%Color and Shape:SolidMolecular weight:467.39OXF BD 02
CAS:OXF BD 02 is a potent and selective BRD4(1) inhibitor (IC50: 382 nM) with anticancer and anti-inflammatory activity.Formula:C18H17NO3Purity:98.25%Color and Shape:SolidMolecular weight:295.33LSD1-IN-24
CAS:LSD1-IN-24 is a selective and potent LSD1 inhibitor with an IC50 value of 0.247 μM.LSD1-IN-24 induces PD-L1 expression and enhances the T cell killing responseFormula:C18H20N2OSPurity:99.53%Color and Shape:SoildMolecular weight:312.43Ref: TM-T67871
1mg57.00€5mg120.00€10mg187.00€25mg374.00€50mg612.00€100mg938.00€500mg1,882.00€1mL*10mM (DMSO)133.00€BRD0639
CAS:BRD0639 is a first-in-class PRMT5-substrate interaction inhibitor for PBM-dependent PRMT5 activity studies.Formula:C21H22ClN5O4SPurity:99.85%Color and Shape:SolidMolecular weight:475.95EEDi-5285
CAS:EEDi-5285: potent EED inhibitor, orally active, IC50=0.2nM, targets EED protein, anti-cancer properties.Formula:C24H22FN5O3SPurity:100%Color and Shape:SolidMolecular weight:479.53(+)-JQ1 PA
CAS:(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1(IC50 of 10.4 nM).Formula:C22H20ClN5OSPurity:98.36%Color and Shape:SolidMolecular weight:437.95Desidustat
CAS:Desidustat is an inhibitor of HIF hydroxylase.Formula:C16H16N2O6Purity:98%Color and Shape:SolidMolecular weight:332.31Ref: TM-T5176
1mg35.00€2mg52.00€5mg94.00€10mg167.00€25mg300.00€50mg516.00€100mg732.00€1ml*10 (DMSO)112.00€Histone Acetyltransferase Inhibitor II
CAS:Histone Acetyltransferase Inhibitor II is a selective and cell permeable inhibitor of p300 histone acetyltransferase(IC50 : 5 μM).with anti-acetylase activityFormula:C20H16Br2O3Purity:97.13%Color and Shape:SolidMolecular weight:464.15(R)-(-)-JQ1 Enantiomer
CAS:(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on BRD4(1/2)(IC50 of 77 nM/33 nM in a cell-free assay)Formula:C23H25ClN4O2SPurity:99.38%Color and Shape:SolidMolecular weight:456.99MZ 1
CAS:MZ 1 is a BRD4 protein degrader based on PROTAC technology.Formula:C49H60ClN9O8S2Purity:99.31%Color and Shape:SolidMolecular weight:1002.64Gandotinib
CAS:LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).Formula:C23H25ClFN7OPurity:99.33% - 99.86%Color and Shape:SolidMolecular weight:469.94Ref: TM-T2638
5mg51.00€10mg88.00€25mg160.00€50mg296.00€100mg469.00€500mg1,035.00€1mL*10mM (DMSO)57.00€JAK2-IN-7
CAS:JAK2-IN-7 selectively inhibits JAK2 (IC50: 3 nM), shows 14-fold selectivity over JAK1/3, FLT3, induces G0/G1 arrest, apoptosis, and has antitumor effects.Formula:C26H33N7OPurity:98.71%Color and Shape:SolidMolecular weight:459.59Ref: TM-T35900
1mg145.00€5mg354.00€10mg630.00€25mg1,301.00€50mg1,738.00€100mg2,357.00€1mL*10mM (DMSO)358.00€AZ-3
CAS:AZ-3 is a potent and selective JAK1 inhibitor (IC50: 34 nM).Formula:C20H28FN7Purity:98%Color and Shape:SolidMolecular weight:385.48JAK-IN-28
CAS:JAK-IN-28 (Compound 111) is a Janus kinase (JAK) inhibitor potentially applicable in the research of cancer and inflammatory diseases [1].Formula:C20H18ClN7OPurity:98%Color and Shape:SolidMolecular weight:407.86AMI-1
CAS:AMI-1 is an effective and selective Histone Methyltransferase (HMT) inhibitor (IC50: 3.0/8.8 μM, for yeast Hmt1p, and human PRMT1).Formula:C21H14N2Na2O9S2Purity:97.53% - 99.9%Color and Shape:DrypowderMolecular weight:548.45Eicosapentaenoic Acid
CAS:Eicosapentaenoic Acid (EPA) is a ω-3 fatty acid abundantly available in marine organisms.Formula:C20H30O2Purity:96.20%Color and Shape:LiquidMolecular weight:302.45Menin-MLL inhibitor MI-2
CAS:Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.Formula:C18H25N5S2Purity:97.46%Color and Shape:SolidMolecular weight:375.55Ref: TM-T2649
2mg42.00€5mg62.00€10mg88.00€25mg169.00€50mg243.00€100mg376.00€200mg550.00€1mL*10mM (DMSO)67.00€MS436
CAS:MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.Formula:C18H17N5O3SPurity:97.95% - 98.92%Color and Shape:SolidMolecular weight:383.42Ref: TM-T1854
2mg44.00€5mg65.00€10mg103.00€25mg192.00€50mg344.00€100mg505.00€500mg1,093.00€1mL*10mM (DMSO)72.00€MBM-17S
CAS:MBM-17S, a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM, effectively inhibits cancer cell proliferation by inducing cell cycle arrest andFormula:C36H40N6O10Purity:98%Color and Shape:SolidMolecular weight:716.74SF2523
CAS:SF2523 is a highly selective and potent inhibitor.Formula:C19H17NO5SPurity:97.78% - 98.06%Color and Shape:SolidMolecular weight:371.41Ref: TM-T3986
1mg37.00€5mg79.00€10mg119.00€25mg274.00€50mg432.00€100mg638.00€500mg1,359.00€1mL*10mM (DMSO)87.00€MI-2-2
CAS:MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.Formula:C17H20F3N5S2Purity:99.56%Color and Shape:SolidMolecular weight:415.5BCI-121
CAS:BCI-121 is a substrate-competitive SMYD3 inhibitor that inhibits the proliferation of the cancer cell.Formula:C14H18BrN3O2Purity:99.67%Color and Shape:SolidMolecular weight:340.22Belzutifan
CAS:"Belzutifan (MK-6482) is an oral HIF-2α inhibitor for ccRCC, with enhanced potency (IC50: 9 nM)."Formula:C17H12F3NO4SPurity:99.34% - 99.41%Color and Shape:SolidMolecular weight:383.34Ref: TM-T16679
1mg70.00€5mg153.00€10mg216.00€25mg411.00€50mg660.00€100mg938.00€200mg1,264.00€1mL*10mM (DMSO)166.00€ACBI1
CAS:ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50sFormula:C49H58FN9O7SPurity:97.54% - 98.15%Color and Shape:SolidMolecular weight:936.1SCH-1473759 hydrochloride
CAS:SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).Formula:C20H27ClN8OSPurity:98.29%Color and Shape:SolidMolecular weight:463Niraparib tosylate monohyrate
CAS:Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.Formula:C26H30N4O5SPurity:99.09%Color and Shape:SolidMolecular weight:510.61Ref: TM-T9497
5mg60.00€10mg87.00€25mg117.00€50mg144.00€100mg216.00€200mg325.00€500mg545.00€1mL*10mM (DMSO)77.00€HIF-2α agonist 2
CAS:HIF-2α agonist 2 is an HIF-2α agonist with an EC50 value of 1.68 μM for HIF-2α.Formula:C13H8Br2N2O2SPurity:98.32%Color and Shape:SoildMolecular weight:416.09NCD38 TFA
NCD38 TFA serves as a selective inhibitor of LSD1 [1] [2].Formula:C37H37ClF3N3O4Purity:98%Color and Shape:SolidMolecular weight:680.16L002
CAS:L002 is a potent inhibitor of acetyltransferase p300 with an IC50 of 1.98 μM, blocking histone and p53 acetylation, and may treat cardiac hypertrophy.Formula:C15H15NO5SPurity:98.59%Color and Shape:SolidMolecular weight:321.35UNC0642
CAS:UNC0642 is an effective and specific G9a/GLP inhibitor (IC50< 2.5 nM).Formula:C29H44F2N6O2Purity:98.75% - 99.5%Color and Shape:SolidMolecular weight:546.7Ref: TM-T4166
1mg40.00€2mg52.00€5mg87.00€10mg131.00€25mg230.00€50mg378.00€100mg567.00€200mg825.00€1mL*10mM (DMSO)95.00€Amodiaquine
CAS:Amodiaquine is a synthetic aminoquinoline, used to treat malaria.Formula:C20H22ClN3OPurity:99.78%Color and Shape:Crystals From Absolute Ethanol SolidMolecular weight:355.86Ref: TM-T8381
1mg52.00€2mg70.00€5mg96.00€10mg173.00€25mg304.00€50mg452.00€100mg647.00€1mL*10mM (DMSO)120.00€DDO-3055
CAS:DDO-3055 is an orally active PHD2 inhibitor utilized in studies related to anemia associated with chronic kidney disease.Formula:C17H13ClN2O5Color and Shape:SolidMolecular weight:360.749BI-847325
CAS:BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.Formula:C29H28N4O2Purity:97.13% - 97.54%Color and Shape:SolidMolecular weight:464.56Ref: TM-T6785
1mg49.00€5mg97.00€10mg153.00€25mg296.00€50mg445.00€100mg660.00€200mg917.00€1mL*10mM (DMSO)97.00€Pumecitinib
CAS:Pumecitinib is a Janus kinase (JAK) inhibitor. Pumecitinib exhibits anti-inflammatory activity.Formula:C17H20N8O2SPurity:99.89%Color and Shape:SoildMolecular weight:400.46LP99
CAS:LP99 is an epigenetic probe.Formula:C26H30ClN3O4SPurity:98.74%Color and Shape:SolidMolecular weight:516.05Ref: TM-T15784
1mg43.00€5mg96.00€10mg145.00€25mg305.00€50mg442.00€100mgTo inquire1mL*10mM (DMSO)97.00€SJ46421
SJ46421, a PROTAC protein degrader derived from (+)-JQ-1, targets KLHDC2. It efficiently forms a stable ternary complex with KLHDC2, exhibiting an IC50 of 7.8 nM. Furthermore, SJ46421 promotes the polyubiquitination of the BD2 domain of BRD2, BRD3, or BRD4.Formula:C42H41ClN8O5S2Color and Shape:SolidMolecular weight:837.41LSD1-IN-6
CAS:LSD1-IN-6, a potent LSD1 inhibitor (IC50: 123 nM), enhances H3K4me2 without altering LSD1 expression. Reversible.Formula:C15H13BrN2O3Purity:98%Color and Shape:SolidMolecular weight:349.18JW 55
CAS:JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2Formula:C25H26N2O5Purity:99.31% - 99.76%Color and Shape:SolidMolecular weight:434.48LSD1-IN-38
LSD1-IN-38 (Compound 23e) is a reversible, orally active inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 1.2 nM. It effectively inhibits the proliferation of cancer cells MV4-11, Kasumi-1, and NCI-H526 with IC50 values of 5, 4, and 11 nM, respectively. Furthermore, LSD1-IN-38 activates CD86 expression with an EC50 of 0.034 μM and induces differentiation in MV4-11 cells. In mouse models, this compound demonstrates antitumor activity.Formula:C30H29F4N5Molecular weight:535.578BRD4770
CAS:BRD4770 is a histone methyltransferase G9a inhibitor and induces cell senescence.Formula:C25H23N3O3Purity:99.82%Color and Shape:SolidMolecular weight:413.47XY1
CAS:XY1 is a very close analogue of SGC707 (a potent, selective, and non-competitive inhibitor of PRMT3 with IC50 of 31 nM), It is intended to be used as aFormula:C17H19N3O2Purity:97.2% - 97.74%Color and Shape:SolidMolecular weight:297.35E7016
CAS:E7016 (GPI 21016) is an orally available PARP inhibitor. E7016 inhibits of DNA repair. E7016 can enhance tumor cell radiosensitivity in vitro and in vivo.Formula:C20H19N3O3Purity:98.16%Color and Shape:SolidMolecular weight:349.38Fosifidancitinib
CAS:Fosifidancitinib is a potent inhibitor of JAK 1 and JAK 3.Formula:C21H21FN5O7PPurity:99.55%Color and Shape:SolidMolecular weight:505.39Ref: TM-T38624
1mg87.00€2mg124.00€5mg187.00€10mg284.00€25mg452.00€50mg645.00€100mg867.00€200mg1,159.00€PROTAC BRD3/BRD4-L degrader-2
PROTAC BRD3/BRD4-L degrader-2, a PROTAC molecule, selectively degrades cellular BRD3 and BRD4-L with K i values of 16.91 and 2.8 nM, respectively, and exhibitsFormula:C43H44ClN7O3Purity:98%Color and Shape:SolidMolecular weight:742.31STAT3-IN-18
CAS:STAT3-IN-18 (compound SPP), a platinum (IV) complex featuring an axial ligand from sandalwood, suppresses the JAK2-STAT3 pathway in breast cancer (BC) cells andFormula:C18H24Cl2N2O6PtPurity:98%Color and Shape:SolidMolecular weight:630.38UNC0321
CAS:UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.Formula:C27H45N7O3Purity:99.25%Color and Shape:SolidMolecular weight:515.69GXF-111
GXF-111, a proteolysis targeting chimera (PROTAC) molecule, efficiently induces the selective degradation of the BRD3 and BRD4-L proteins.Formula:C42H42ClN7O3Purity:98%Color and Shape:SolidMolecular weight:728.28JAK1-IN-8
CAS:JAK1-IN-8, a specific inhibitor of Janus kinase 1 (JAK1, IC50<500 nM).Formula:C22H23FN4O3SPurity:98.36%Color and Shape:SolidMolecular weight:442.51Ref: TM-T35899
5mg47.00€10mg79.00€25mg144.00€50mg250.00€100mg424.00€200mg568.00€1mL*10mM (DMSO)50.00€MI-136
CAS:MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced.Formula:C23H21F3N6SPurity:97.08% - 98.63%Color and Shape:SolidMolecular weight:470.51Ref: TM-T6889
1mg47.00€5mg87.00€10mg147.00€25mg279.00€50mg472.00€100mg730.00€200mg1,017.00€1mL*10mM (DMSO)97.00€BETd-260
CAS:BETd-260, a PROTAC linked by a Cereblon ligand and a BET ligand, has an inhibitory effect on BRD4 protein in leukemic cell lines.Formula:C43H46N10O6Purity:96.76%Color and Shape:SolidMolecular weight:798.89AU-15330
CAS:AU-15330 is a proteolytic targeting chimera (PROTAC) that simultaneously targets SMARCA4, SMARCA2, and PBRM1 for degradation and exhibits cytotoxicity in H3.3K27M cells but not in H3 wild-type cells. Cost-effective and quality-assured.Formula:C39H49N9O5SPurity:100% - 98.21%Color and Shape:SolidMolecular weight:755.93Albendazole
CAS:Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.Formula:C12H15N3O2SPurity:98.21% - 98.76%Color and Shape:Colorless Crystals SolidMolecular weight:265.33CPI-169 racemate
CAS:CPI-169 racemate (CPI 169) is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.Formula:C27H36N4O5SPurity:99.59%Color and Shape:SolidMolecular weight:528.66Ref: TM-T6809
1mg56.00€2mg79.00€5mg125.00€10mg172.00€25mg376.00€50mg560.00€100mg797.00€1mL*10mM (DMSO)145.00€S-Ruxolitinib
CAS:S-Ruxolitinib can be used in related research in the field of life sciences. Its product number is T3066 and CAS number is 1160597-27-2.Formula:C17H18N6Purity:98%Color and Shape:SolidMolecular weight:306.37MAT2A inhibitor 2
CAS:MAT2A inhibitor 2 is an inhibitor of methionine adenosyltransferase 2A (MAT2A).Formula:C18H24ClN3O3Purity:99.52%Color and Shape:SolidMolecular weight:365.85Ref: TM-T11950
1mg51.00€5mg106.00€10mg169.00€25mg298.00€50mg445.00€100mg655.00€500mg1,359.00€1mL*10mM (DMSO)119.00€Venadaparib
CAS:Venadaparib, a PARP inhibitor (IC50: 1.4/1.0 nM for PARP1/2), is orally active, selective, not affecting PARP-5, used in tumor studies.Formula:C23H23FN4O2Purity:98.47%Color and Shape:SolidMolecular weight:406.45Ref: TM-T9430
1mg48.00€2mg63.00€5mg96.00€10mg144.00€25mg283.00€50mg464.00€100mg680.00€1mL*10mM (DMSO)96.00€PROTAC BRD9 Degrader-6
CAS:PROTAC BRD9 Degrader-6, with an IC50 value of 0.13 nM, is a potent degrader of BRD9 suitable for research on BAF complex-related disorders [1].Formula:C47H56N8O6Purity:98%Color and Shape:SolidMolecular weight:829(Rac)-BAY1238097
CAS:(Rac)-BAY1238097 is a inhibitor of BET(IC50 of 1.02 μM for BRD4),used in cancer research.Formula:C25H33N5O3Purity:98%Color and Shape:SolidMolecular weight:451.56MS023 dihydrochloride
CAS:MS023 dihydrochloride (MS023 2HCl) is a human type I protein arginine methyltransferase inhibitor with antitumour activity for the study of breast cancer.Formula:C17H27Cl2N3OPurity:99.52%Color and Shape:SolidMolecular weight:360.32LNK01004
CAS:LNK01004 is a JAK inhibitor that exhibits potent inhibitory effects on JAK1 (IC50: 10 nM), JAK2 (IC50: ＜0.51 nM), and TYK2 (IC50: 1.0 nM). It can concurrently inhibit multiple cytokine-induced p-STAT signaling pathways and is applicable for research on diseases such as atopic dermatitis.Formula:C26H31N7O2Color and Shape:SolidMolecular weight:473.57Londamocitinib
CAS:Londamocitinib (JAK1-IN-7) is a selective and potent JAK1 inhibitor with anti-inflammatory activity.Formula:C28H31F2N7O4SPurity:99.47%Color and Shape:SolidMolecular weight:599.65Ref: TM-T11706
1mg180.00€5mg439.00€10mg597.00€25mg905.00€50mg1,169.00€100mg1,568.00€1mL*10mM (DMSO)567.00€IDF-11774
CAS:IDF-11774 is a HIF-1 inhibitor.It reduces hif-1α HRE luciferase activity (IC50 = 3.65 μM).Formula:C23H32N2O2Purity:98.05%Color and Shape:SolidMolecular weight:368.51PFI-2
CAS:PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over otherFormula:C23H25F4N3O3SPurity:99.38%Color and Shape:SolidMolecular weight:499.52Methylstat
CAS:Methylstat is a methyl ester prodrug of a Jumonji C domain-containing histone demethylase (JMJD) inhibitor that has favorable cell permeability.Formula:C28H31N3O6Purity:98.34% - 98.34%Color and Shape:SolidMolecular weight:505.56NU 9056
CAS:NU 9056 is an effective and selective inhibitor of KAT5 histone acetyltransferase with an IC50 of 2 µM.Formula:C6H4N2S4Purity:95.36%Color and Shape:SolidMolecular weight:232.37Gentiakochianin
CAS:Gentiakochianin (Swertianine), vasodilatory, induce G(2)/M phase and inhibits proliferation, reduces oxLDL-induced , inhibits ROS s,up-regulated Akt/CREB/eNOS.Formula:C14H10O6Purity:98.97%Color and Shape:SolidMolecular weight:274.23E-7386
CAS:E-7386 is an oral active CBP/ -catenin modulator.Formula:C39H48FN9O4Purity:98.92% - 99%Color and Shape:SolidMolecular weight:725.85Ref: TM-T11136
1mg87.00€5mg255.00€10mg376.00€25mg647.00€50mg920.00€100mg1,225.00€1mL*10mM (DMSO)399.00€MLN8054
CAS:MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.Formula:C25H15ClF2N4O2Purity:98.07% - 98.26%Color and Shape:SolidMolecular weight:476.86Ref: TM-T6315
1mg52.00€2mg71.00€5mg88.00€10mg127.00€25mg233.00€50mg376.00€100mg567.00€1mL*10mM (DMSO)93.00€CPI-637
CAS:CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor.Formula:C22H22N6OPurity:99.75% - 99.91%Color and Shape:SolidMolecular weight:386.45GNE-064
CAS:GNE-064: Oral SMARCA4/2, PBRM1 inhibitor; IC50 (SMARCA4)=0.035µM, EC50 (SMARCA2)=0.1µM; High solubility; Research probe.Formula:C17H21N5O2Purity:99.81%Color and Shape:SoildMolecular weight:327.38PROTAC HDAC6 degrader 4
PROTAC HDAC6 degrader4 (Compound 17c) is a PROTAC that targets and degrades HDAC6, with a DC50 of 14 nM. It exhibits inhibitory activity against HDAC1, HDAC2, HDAC3, and HDAC6, with IC50 values of 2.2, 2.37, 0.61, and 0.295 μM, respectively. [Pink: ligand for target protein HDAC6 ligand-3; Black: linker; Blue: ligand for cereblon E3 ligase]Formula:C39H42FN9O7Color and Shape:SolidMolecular weight:767.81PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formula:C22H26N4O3Purity:98.82%Color and Shape:SolidMolecular weight:394.47PARP1-IN-30
CAS:PARP1-IN-30 is a specific and effective PARP1 inhibitor with cytotoxic properties. It precisely inhibits PARP1 in tumor cells lacking breast cancer 1 protein (BRCA1) or BRCA2. PARP1-IN-30 holds potential for use in cancer research.Formula:C14H12ClNO4SColor and Shape:SolidMolecular weight:325.77(R)-9b
CAS:(R)-9b is an effective inhibitor of the ACK1 tyrosine kinase (IC50=56 nM) and exhibits anticancer activity. It selectively targets ACK1 but also inhibits kinases in the JAK family, specifically JAK2 and Tyk2. (R)-9b is used in research related to hormone-regulated cancers, such as prostate cancer and breast cancer.Formula:C20H27ClN6OColor and Shape:SolidMolecular weight:402.92BGP-15
CAS:BGP-15 (BGP-15 2HCl) is a PARP inhibitor with protecting effect after ischemia-reperfusion injury.Formula:C14H24Cl2N4O2Purity:99.02% - 99.89%Color and Shape:SolidMolecular weight:351.27L-2-Hydroxyglutaric acid
CAS:L-2-Hydroxyglutaric acid (L-2-HG) is a substrate of L2HGDH and inhibits histone demethylases.Formula:C5H8O5Purity:98%Color and Shape:SolidMolecular weight:148.11(S)-GNE-987
(S)-GNE-987 binds to the BRD4 BD1(IC50=4 nM) and BD2 (3.9 nM) bromodomains and can be used to design PROTAC-Antibody Conjugate (PAC).Formula:C56H67F2N9O8S2Purity:98%Color and Shape:SolidMolecular weight:1096.31Tz-Thalidomide
CAS:Tz-Thalidomide is a tetrazine-modified Thalidomide (E3 ligase ligand) with some affinity for BRD4.Formula:C29H29N7O6Purity:98.34%Color and Shape:SolidMolecular weight:571.58JNJ-7706621
CAS:JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.Formula:C15H12F2N6O3SPurity:99.1% - 99.66%Color and Shape:SolidMolecular weight:394.36Ref: TM-T6126
1mg50.00€2mg66.00€5mg105.00€10mg180.00€25mg284.00€50mg520.00€100mg728.00€500mg1,473.00€1mL*10mM (DMSO)88.00€SW2_110A
CAS:SW2_110A: Cell-permeable, CBX8 ChD inhibitor, Kd 800 nM; 5x selective over other CBXs in vitro.Formula:C42H60N6O7Purity:98%Color and Shape:SolidMolecular weight:760.96SD-1029
CAS:SD-1029 is a JAK2 inhibitor and a novel Stat3 activation inhibitor that inhibits Stat3 phosphorylation and JAK-STAT signaling.Formula:C25H32Br2Cl2N2O3Color and Shape:SolidMolecular weight:639.25Y06137
CAS:Y06137, selective BET inhibitor, Kd 81 nM for BRD4(1), researched for castration-resistant prostate cancer treatment.Formula:C27H32N4O2Purity:97.27%Color and Shape:SolidMolecular weight:444.57K00135
CAS:K00135 (IMIDAZOPYRIDAZIN 1) is a selective inhibitor of Pim kinases and can be used in studies about gastric cancer and antileukemic therapeutics.Formula:C18H18N4OPurity:97.88%Color and Shape:SolidMolecular weight:306.36Ref: TM-T27704
1mg185.00€2mg279.00€5mg426.00€10mg627.00€25mg938.00€50mg1,320.00€100mg1,786.00€500mg3,591.00€1mL*10mM (DMSO)415.00€MS023
CAS:MS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 nM, 119 nM, 83 nM, 4 nM, and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8,Formula:C17H25N3OPurity:98.31% - 99.28%Color and Shape:SolidMolecular weight:287.4Ref: TM-T6900
1mg39.00€2mg51.00€5mg88.00€10mg119.00€25mg243.00€50mg378.00€100mg560.00€500mg1,216.00€1mL*10mM (DMSO)84.00€Abrocitinib
CAS:Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).Formula:C14H21N5O2SPurity:99.09% - 99.91%Color and Shape:SolidMolecular weight:323.41Ref: TM-TQ0037
1mg85.00€2mg107.00€5mg167.00€10mg284.00€25mg467.00€50mg692.00€100mg938.00€1mL*10mM (DMSO)188.00€GSK-5959
CAS:GSK-5959 is a selective BRPF1 inhibitor with IC50 ~80 nM, 100-fold more specific than 35 other bromodomains.Formula:C22H26N4O3Purity:98.35% - 98.65%Color and Shape:SolidMolecular weight:394.47SW2_110A acetate
SW2_110A acetate is a selective, cell-permeable chromobox inhibitor of homologue CBX8 (Kd = 800 nM) bound to CBX8 N-terminal color gamut (ChD).Formula:C44H64N6O9Purity:98%Color and Shape:SoildMolecular weight:821.01Cedazuridine
CAS:Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.Formula:C9H14F2N2O5Purity:99.46%Color and Shape:SolidMolecular weight:268.21KDM5-C49 HCl
KDM5-C49 HCl (KDOAM-20 hydrochloride) is a potent and selective inhibitor of KDM5 demethylase.Formula:C15H25ClN4O3Purity:98.59%Color and Shape:SolidMolecular weight:344.84Ref: TM-T27723L
1mg185.00€5mg409.00€10mg605.00€25mg938.00€50mg1,293.00€100mg1,738.00€500mg3,496.00€1mL*10mM (DMSO)420.00€VPC-70063
CAS:VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) is an inhibitor of c-Myc-MAX.Formula:C16H12F6N2SPurity:99.93%Color and Shape:SolidMolecular weight:378.34Ref: TM-T60019
1mg51.00€5mg106.00€10mg160.00€25mg283.00€50mg406.00€100mg592.00€200mg835.00€1mL*10mM (DMSO)137.00€PARP10-IN-2
CAS:PARP10-IN-2 is a potent inhibitor of PARP10, a mono-ADP-ribosyltransferase, with an IC50 value of 3.64 μM for human PARP10.PARP10-IN-2 also inhibited PARP2 andFormula:C14H10N2O2Purity:99.68%Color and Shape:SolidMolecular weight:238.24PF-CBP1 hydrochloride
CAS:PF-CBP1 HCl selectively inhibits CREBBP bromodomain (IC50: 125 nM) and p300 (IC50: 363 nM).Formula:C29H37ClN4O3Purity:97.11% - 99.02%Color and Shape:SolidMolecular weight:525.08Eleven-Nineteen-Leukemia Protein IN-2
CAS:Eleven-Nineteen-Leukemia Protein IN-2 (compound 23), an ENL inhibitor, exhibits an IC50 of 10.7 nM and is utilized for leukemia research [1].Formula:C22H23N5O2Purity:98%Color and Shape:SolidMolecular weight:389.45PF-06821497
CAS:PF-06821497 is a selective inhibitor of EZH2 with significant tumor growth inhibition.Cost-effective and quality-assured.Formula:C22H24Cl2N2O5Purity:97.88%Color and Shape:SolidMolecular weight:467.34Citric acid trilithium salt tetrahydrate
CAS:Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy ofFormula:C6H13Li3O11Purity:≥95%Color and Shape:White Crystalline PowderMolecular weight:281.98CF53
CAS:CF53: potent, selective oral BET inhibitor; Ki <1 nM, Kd 2.2 nM, IC50 2 nM for BRD4 BD1; high affinity for BRD2/3/4/BRDT; effective anti-tumor agent.Formula:C24H25N7O2Purity:99.72%Color and Shape:SolidMolecular weight:443.5Ref: TM-T10773
1mg96.00€5mg212.00€10mg316.00€25mg510.00€50mg695.00€100mg940.00€1mL*10mM (DMSO)226.00€CEP-33779
CAS:CEP-33779 is a novel and selective inhibitor of JAK2 with an IC50 of 1.8±0.6 nM.Formula:C24H26N6O2SPurity:98.81% - ≥95%Color and Shape:SolidMolecular weight:462.57Ref: TM-T6122
1mg46.00€2mg59.00€5mg87.00€10mg144.00€25mg245.00€50mg376.00€100mg560.00€500mg1,216.00€1mL*10mM (DMSO)97.00€GSK484 hydrochloride
CAS:GSK484 hydrochloride (GTPL8577) is a reversible peptidyl-arginine deiminase 4 (PAD4) inhibitor.Cost-effective and quality-assured.Formula:C27H32ClN5O3Purity:98.32% - 99.62%Color and Shape:SolidMolecular weight:510.03Ref: TM-TQ0067
1mg74.00€5mg156.00€10mg227.00€25mg457.00€50mg655.00€100mg933.00€1mL*10mM (DMSO)167.00€CBP-IN-1
CAS:CBP-IN-1 (compound 12) acts as a potent CBP inhibitor exhibiting an IC50 of 1.5 nM and additionally suppresses CBP BRET and BRD4(1) with IC50 values of 690 nMFormula:C27H33F2N7OPurity:98%Color and Shape:SolidMolecular weight:509.59RBN-3143
CAS:RBN-3143: potent PARP14 inhibitor (IC50= 4 nM), blocks ADP-ribosylation, may treat lung inflammation.Formula:C22H28FN3O4SPurity:98.64%Color and Shape:SoildMolecular weight:449.54Ref: TM-T67844
1mg95.00€5mg202.00€10mg298.00€25mg507.00€50mg730.00€100mg1,026.00€500mg2,052.00€1mL*10mM (DMSO)224.00€Vafidemstat
CAS:Vafidemstat (ORY-2001) is a lysine-histone demethylase (LSD1)/MAO-B inhibitor for the study of neurological disorders.Formula:C19H20N4O2Purity:99.53%Color and Shape:SolidMolecular weight:336.395-Methyl-2'-deoxycytidine
CAS:5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.Formula:C10H15N3O4Purity:99.18% - 99.69%Color and Shape:SolidMolecular weight:241.24LSD1-IN-20
CAS:LSD1-IN-20: Dual LSD1/G9a inhibitor, Ki 0.44/0.68 μM; hampers THP-1, MDA-MB-231 cell growth with IC50 0.51/1.60 μM at 72h.Formula:C27H38N6O2Purity:98.21% - 98.72%Color and Shape:SolidMolecular weight:478.63Phthalazinone pyrazole
CAS:Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.Formula:C18H15N5OPurity:97.03%Color and Shape:SolidMolecular weight:317.34Ref: TM-T21981
1mg64.00€2mg96.00€5mg145.00€10mg212.00€25mg353.00€50mg532.00€100mg792.00€200mg1,064.00€PROTAC BRD4-DCAF1 degrader-1
CAS:PROTACBRD4-DCAF1 degrader-1 (I-907) is a PROTAC degrader targeting BRD4-DCAF1, exhibiting a DC50 range of 10~100 nM.Formula:C60H64Cl2F2N8O9SColor and Shape:SolidMolecular weight:1182.17Talazoparib tosylate
CAS:PF-3882845 is an MR antagonist that binds to the progesterone receptor (PR) and is used in the study of endocrine disorders and urogenital disorders.Formula:C26H22F2N6O4SPurity:99.79%Color and Shape:SolidMolecular weight:552.55Ref: TM-T16979
2mg42.00€5mg62.00€10mg88.00€25mg135.00€50mg188.00€100mg311.00€200mg432.00€1mL*10mM (DMSO)74.00€Ref: TM-T5S2358
1mg57.00€2mg81.00€5mg111.00€10mg160.00€25mg263.00€50mg378.00€100mg558.00€200mg797.00€1mL*10mM (DMSO)123.00€Aurora Kinases-IN-4
CAS:Aurora Kinases-IN-4 (Compound 11c) is a covalent, ATP-competitive inhibitor of aurora kinase A with an IC50 value of 1.7 nM.Formula:C26H28N8OPurity:98%Color and Shape:SolidMolecular weight:468.55ZZM-1220
ZZM-1220, a covalent inhibitor of histone lysine methyltransferase G9a/GLP, exhibits IC50 values of 458 nM for G9a and 924 nM for GLP.Formula:C25H29N5O3Purity:98%Color and Shape:SolidMolecular weight:447.53Nanaomycin A
CAS:Nanaomycin A, a quinone antibiotic, reactivates cancer suppressor genes and inhibits DNMT3B (IC50=500nM).Formula:C16H14O6Purity:98%Color and Shape:SolidMolecular weight:302.28JAK1-IN-11
CAS:JAK1-IN-11 (compound 11) serves as a potent inhibitor of Janus kinases, exhibiting nanomolar inhibitory concentrations with IC50 values of 0.02 nM (JAK1) and 0.Formula:C26H36N6O4SPurity:98%Color and Shape:SolidMolecular weight:528.67Lorpucitinib
CAS:Lorpucitinib (JNJ-64251330) is a JAK kinase inhibitor used in the study of inflammatory and gastrointestinal diseases.Formula:C22H28N6O2Purity:99.72%Color and Shape:SolidMolecular weight:408.5Wnt/β-catenin-IN-5
Wnt/β-catenin-IN-5 (Compound 4) functions as an inhibitor of the Wnt/β-catenin signaling pathway. This compound effectively eradicates colorectal cancer stem cells and inhibits tumor growth by suppressing the Wnt signaling pathway. Additionally, Wnt/β-catenin-IN-5 promotes the degradation of KDM3A and KDM3B.Formula:C33H37N5O10Color and Shape:SolidMolecular weight:663.67UNC 0631
CAS:UNC 0631 is a effectvie histone methyltransferase G9a inhibitor (IC50=4 nM).Formula:C37H61N7O2Purity:98.76%Color and Shape:SolidMolecular weight:635.93DC-05
CAS:DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively).Formula:C25H25N3OPurity:98.95%Color and Shape:SolidMolecular weight:383.49Ref: TM-T15080
1mg74.00€5mg160.00€10mg264.00€25mg562.00€50mg932.00€100mg1,320.00€200mg1,776.00€1mL*10mM (DMSO)170.00€L 888607 Racemate
CAS:L 888607 Racemate blocks DP1 and TP receptors with 132 nM and 17 nM affinity.Formula:C19H15ClFNO2SColor and Shape:SolidMolecular weight:375.84Pim-1 kinase inhibitor 5
CAS:Pim-1 kinase inhibitor 5 (Compound 4c), with an IC50 of 0.61 μM, exhibits cytotoxicity against various cancer cell lines, including HepG2, MCF-7, PC3, and HCT-Formula:C22H13Cl2N3OPurity:98%Color and Shape:SolidMolecular weight:406.26FIDAS-3
CAS:FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activitiesFormula:C16H15F2NPurity:97.75%Color and Shape:SolidMolecular weight:259.29Ref: TM-T11284
5mg52.00€10mg78.00€25mg134.00€50mg192.00€100mg279.00€200mg374.00€1mL*10mM (DMSO)50.00€3',4'-Dimethoxyflavone
CAS:3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities.Formula:C17H14O4Purity:98.05% - 98.05%Color and Shape:SolidMolecular weight:282.29dBET1
CAS:dBET1 fuses (+)-JQ1 with thalidomide, degrades BET proteins via cereblon (EC50: 430 nM), and triggers apoptosis.Formula:C38H37ClN8O7SPurity:98.14% - 99.3%Color and Shape:SolidMolecular weight:785.27Ref: TM-T4495
1mg52.00€5mg104.00€10mg170.00€25mg283.00€50mg452.00€100mg687.00€500mg1,415.00€1mL*10mM (DMSO)169.00€BET-IN-2
CAS:BET-IN-2 is a BET inhibitor (IC50: 52 nM for BRD4-BD1).Formula:C23H29N3OPurity:98%Color and Shape:SolidMolecular weight:363.5IOX2
CAS:IOX2 is a selective HIF PHD inhibitor, active in cells with 21 nM IC50 for PHD2/ELGN-1, not inhibiting FIH at 20uM.Formula:C19H16N2O5Purity:98% - 99.59%Color and Shape:SolidMolecular weight:352.34TP-3654
CAS:TP-3654 is a second-generation Pim kinase inhibitor (Ki values against Pim-1/3: 5/42 nM).Formula:C22H25F3N4OPurity:97.72% - 99.95%Color and Shape:SolidMolecular weight:418.46Fenbendazole
CAS:Fenbendazole (Fenbendazol) is an antinematodal benzimidazole used in veterinary medicine.Formula:C15H13N3O2SPurity:99.74%Color and Shape:White To Yellowish PowderMolecular weight:299.355-Azacytidine
CAS:5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.Formula:C8H12N4O5Purity:99.31% - 99.79%Color and Shape:Crystals From Methanol Physical Description White Crystalline Powder (Ntp 1992)Molecular weight:244.2Izilendustat
CAS:Tert-butyl compound inhibits human EGLN-1; confirmed by spectrometry after 20 mins.Formula:C22H28ClN3O4Purity:99.95%Color and Shape:SolidMolecular weight:433.93Ref: TM-T64336
5mg46.00€10mg64.00€25mg109.00€50mg170.00€100mg273.00€200mg399.00€1mL*10mM (DMSO)49.00€ARTD10/PARP10-IN-1
CAS:ARTD10/PARP10-IN-1 is a PARP inhibitor that inhibits ARTD8/PARP14 and has anticancer and antitumour activity for the study of prostate cancer.Formula:C12H12N2O4Purity:99.14%Color and Shape:SolidMolecular weight:248.23PARP1-IN-15
PARP1-IN-15 (Compound 6) is a PARP1 inhibitor that also inhibits tankyrase (TNKS) and promotes DNA double-strand breaks, leading to tumor cell apoptosis.Formula:C16H12N2O2Purity:98%Color and Shape:SolidMolecular weight:264.28VHL-IN-1
VHL-IN-1 (compound 30), a ubiquitin E3 ligase von Hippel-Lindau (VHL) inhibitor with a dissociation constant (Kd) of 37 nM, potently stabilizes HIF-1α andFormula:C28H37FN4O4SPurity:98%Color and Shape:SolidMolecular weight:544.68SETDB1-TTD-IN-1
CAS:SETDB1-TTD-IN-1 is a potent and selective inhibitor of SET domain bifurcated protein 1 tandem tudor domain (SETDB1-TTD, Kd = 88 nM).Cost-effective and quality-assured.Formula:C28H31N5O2Purity:98.26% - 99.38%Color and Shape:SolidMolecular weight:469.58MRS2698
CAS:MRS2698: potent P2Y2 agonist, EC50 8 nM, >300x selectivity over P2Y4/P2Y6.Formula:C9H16N3O13P3SPurity:98%Color and Shape:SolidMolecular weight:499.22Dot1L-IN-1
CAS:The Ki value of DOT1L-in-1 is 2pm.It is a highly effective, selective and novel Dot1L inhibitor.Formula:C32H36ClN9O2SPurity:98%Color and Shape:SolidMolecular weight:646.21Ryuvidine
CAS:Ryuvidine is a dual inhibitor of KDM5A and SETD8, an inducer of the DNA damage response, and can be used to study breast cancer and erythroderma.Formula:C15H12N2O2SPurity:98.6%Color and Shape:SolidMolecular weight:284.33Menin-MLL inhibitor 27
Menin-MLL inhibitor 27 effectively inhibits the interaction between Menin and MLL, serving as a potential tool in cancer research, particularly for acuteFormula:C31H35FN8O2Purity:98%Color and Shape:SolidMolecular weight:570.66ZL0420
CAS:ZL0420: Potent, selective BRD4 inhibitor, IC50 27 nM BD1 & 32 nM BD2.Formula:C16H16N4O2Purity:97.77%Color and Shape:SolidMolecular weight:296.32Ref: TM-T6828
2mg42.00€5mg64.00€10mg101.00€25mg197.00€50mg340.00€100mg484.00€200mg645.00€1mL*10mM (DMSO)70.00€Iadademstat dihydrochloride
CAS:Iadademstat dihydrochloride (ORY-1001(trans)) , a Potent and Selective Covalent KDM1A/LSD1 Inhibitor, for the Treatment of Acute Leukemia.Formula:C15H24Cl2N2Purity:99.78%Color and Shape:SolidMolecular weight:303.27PIM1-IN-1
CAS:PIM1-IN-1 inhibits PIM1/3 with IC50s: PIM1 (7 nM), PIM2 (5530 nM), PIM3 (70 nM); it has anti-cancer properties.Formula:C25H30N8O2Purity:98%Color and Shape:SolidMolecular weight:474.56BMS-986158
CAS:BMS-986158: BET inhibitor, IC50 of 6.6 nM in SCLC, 5 nM in TNBC cells.Formula:C30H33N5O2Purity:98.78%Color and Shape:SolidMolecular weight:495.62Ref: TM-T14685
1mg87.00€5mg259.00€10mg465.00€25mg745.00€50mg1,026.00€100mg1,388.00€1mL*10mM (DMSO)283.00€GNE-207
CAS:GNE-207 is a selective and orally bioavailable inhibitor of the bromodomain of CBP (IC50: 1 nM).Formula:C29H30N6O3Purity:98%Color and Shape:SolidMolecular weight:510.59HIF-2α-IN-2
CAS:HIF-2α-IN-2 is a hypoxia-inducible factor (HIF-2α) inhibitor (IC50: 16 nM in scintillation proximity assay).Formula:C17H13F2NO4SPurity:99.24%Color and Shape:SolidMolecular weight:365.35Ref: TM-T11561
1mg71.00€5mg135.00€10mg178.00€25mg309.00€50mg447.00€100mg620.00€200mg835.00€1mL*10mM (DMSO)149.00€A1874
CAS:A1874 is a nutlin-based and BRD4-degrading PROTAC which induces BRD4 degradation in cells. Effective in inhibiting many cancer cell lines proliferation.Formula:C58H62Cl3F2N9O7SPurity:99.52%Color and Shape:SolidMolecular weight:1173.59TP-472
CAS:TP-472 is a selective inhibitor of BRD9 (Kd: 33 nM).Formula:C20H19N3O2Purity:98%Color and Shape:SolidMolecular weight:333.38JDTic dihydrochloride
CAS:JDTic is a powerful antagonist of kappa-opioid receptors (KOR), effectively inhibiting the antinociceptive effects induced by the κ-agonist U50, 488.Formula:C28H41Cl2N3O3Purity:98%Color and Shape:SolidMolecular weight:538.55PARP/PI3K-IN-1
CAS:PARP/PI3K-IN-1 is a PARP and PI3K dual inhibitor with anticancer and antiproliferative activities for the study of breast, pancreatic and lung cancers.Formula:C33H28F4N8O3Purity:99.59%Color and Shape:SolidMolecular weight:660.62HS94
CAS:HS94 (DAPK3 inhibitor HS94) is a selective and potent DAPK3 inhibitor with a Ki value of 126 nM for Pim kinase inhibition and can be used to study hypertension.Formula:C15H15N5O2SPurity:95.04%Color and Shape:SolidMolecular weight:329.382-methyl-2,3,4,5-tetrahydro-1,5-benzothiazepin-4-one
CAS:2-methyl-2,3-dihydro-1,5-benzothiazepin-4(5H)-one is ligand of CBP.Formula:C10H11NOSPurity:99.68%Color and Shape:SolidMolecular weight:193.27ABBV-744
CAS:ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.Formula:C28H30FN3O4Purity:100% - 99.79%Color and Shape:SolidMolecular weight:491.55Ref: TM-T4697
1mg47.00€2mg59.00€5mg96.00€10mg150.00€25mg299.00€50mg432.00€100mg527.00€200mg758.00€1mL*10mM (DMSO)96.00€Butyrolactone 3
CAS:Butyrolactone 3 (MB-3) is a Gcn5 inhibitor with weak affinity for CBP.Butyrolactone 3 has antimicrobial activity and can be used in cancer.Formula:C9H12O4Purity:98.99% - 99.5%Color and Shape:SolidMolecular weight:184.19Menin-MLL inhibitor 29
Menin-MLL Inhibitor 29 (Compound C1) is a Menin-MLL protein-protein interaction (PPI) inhibitor that demonstrates high affinity to Menin with a dissociationFormula:C36H26Br2F6N4PRhPurity:98%Color and Shape:SolidMolecular weight:922.3LSD1-UM-109
CAS:LSD1-UM-109 is a highly potent and reversible inhibitor of LSD1, demonstrating an IC50 of 3.1 nM.Formula:C29H27FN6Purity:98%Color and Shape:SolidMolecular weight:478.56JAK-IN-5
CAS:JAK-IN-5 is a JAK inhibitor.Formula:C27H31FN6OPurity:97.78% - 98.78%Color and Shape:SolidMolecular weight:474.57Ref: TM-T11710
1mg187.00€5mg391.00€10mg582.00€25mg929.00€50mg1,254.00€100mg1,691.00€500mg3,382.00€1mL*10mM (DMSO)567.00€PARP7-IN-15
CAS:PARP7-IN-15 (Compound 18) is a potent PARP7 inhibitor exhibiting an IC50 of 0.56 nM and demonstrates antitumor activity [1].Formula:C23H24F6N6O4Purity:98%Color and Shape:SolidMolecular weight:562.46Pulrodemstat
CAS:Pulrodemstat (CC-90011) is an LSD1 inhibitor with anticancer and antitumor activity, inhibiting proliferation and migration of HNSCC cells.Formula:C24H23F2N5O2Purity:98.11% - 98.89%Color and Shape:SolidMolecular weight:451.47KF21213
CAS:KF21213 shows a high affinity for the adenosine A2A receptors (Ki=3.0 nM). KF21213 is a highly selective ligand for mapping CNS adenosine A2A receptors.Formula:C19H22N4O3Purity:98%Color and Shape:SolidMolecular weight:354.4Pim-1 kinase inhibitor 8
CAS:Pim-1 kinase inhibitor 8 is a Pim-1 kinase inhibitor with anticancer activity that inhibits cell migration and can be studied in breast cancer.Formula:C14H17N3O3Purity:99.81%Color and Shape:SoildMolecular weight:275.3Menin-MLL inhibitor 20
CAS:Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.Formula:C33H40N8O4Purity:98.89%Color and Shape:SolidMolecular weight:612.72Ref: TM-T9399
1mg40.00€5mg90.00€10mg135.00€25mg264.00€50mg390.00€100mg555.00€200mg752.00€1mL*10mM (DMSO)90.00€KSQ-4279
CAS:KSQ-4279 (USP1-IN-1) is an inhibitor of USP1 and PARP.KSQ-4279 has anticancer activity and is used in the study of non-small cell lung cancer, osteosarcoma,Formula:C27H25F3N8OPurity:99.43% - 99.76%Color and Shape:SoildMolecular weight:534.54CCT129202
CAS:CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 μM, 0.198 μM and 0.227 μM, respectively.Formula:C23H25ClN8OSPurity:98.14%Color and Shape:SolidMolecular weight:497.025-Hydroxymethyl-2'-deoxycytidine
CAS:5-Hydroxymethyl-2'-deoxycytidine is an oxidized derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA, causing DNA damage reactions, chromosomal aberrations,Formula:C10H15N3O5Purity:99.8%Color and Shape:SolidMolecular weight:257.24Ref: TM-T40834
1mg40.00€5mg88.00€10mg119.00€25mg202.00€50mg323.00€100mg487.00€500mg1,035.00€1mL*10mM (DMSO)87.00€Uzansertib phosphate
CAS:Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase, inhibiting PIM1, PIM2 and PIM3.Formula:C26H29F3N5O7PPurity:99.75% - 99.85%Color and Shape:SolidMolecular weight:611.51MI-503
CAS:MI-503 is an efficient and selective Menin-MLL inhibitor. MI-503 has a significant inhibitory effect on human MLL leukemia cell line. Cost-effective and quality-assured.Formula:C28H27F3N8SPurity:99.87% - 99.99%Color and Shape:SolidMolecular weight:564.63Ref: TM-TQ0069
2mg115.00€5mg208.00€10mg348.00€25mg520.00€50mg750.00€100mg1,035.00€200mg1,406.00€1mL*10mM (DMSO)259.00€BRD7-IN-3
BRD7-IN-3 (compound 1-78) functions as a dual inhibitor targeting the bromodomain-containing proteins BRD7 and BRD9, demonstrating half-maximal inhibitoryFormula:C18H18N2O2Purity:98%Color and Shape:SolidMolecular weight:294.35JPHM-2-167
CAS:PHM-2-167 (Compound 11) is a selective inhibitor of the prolyl hydroxylase domain enzyme (PHD). It inhibits PHD2 and PHD3 with IC50 values of 0.253 μM and 3.95 μM, respectively. PHM-2-167 is applicable for research in chronic kidney disease.Formula:C30H28N6O2Color and Shape:SolidMolecular weight:504.582GSK2807 Trifluoroacetate
CAS:GSK2807 Trifluoroacetate is a selective and SAM-competitive inhibitor of SMYD3 (Ki: 14 nM; IC50: 130 nM).Formula:C21H33F3N8O7Purity:99.95%Color and Shape:SolidMolecular weight:566.53CARM1-IN-1
CAS:CARM1-IN-1 (CARM1-IN-7G) is a selective inhibitor of CARM1 with IC50 of 8.6 μM. CARM1-IN-1 shows weak activity against PRMT1 and SET7 with IC50 > 600 μM.Formula:C26H21Br2NO3Purity:97.35%Color and Shape:SolidMolecular weight:555.26Ref: TM-T10682L
1mg37.00€5mg88.00€10mg127.00€25mg250.00€50mg406.00€100mg632.00€200mg883.00€1mL*10mM (DMSO)97.00€Golidocitinib
CAS:Golidocitinib (AZD4205) is a selective JAK1 inhibitor (IC50: 73 nM) and weakly inhibits JAK2/JAK3 (IC50: >14.7, >30 μM).Formula:C25H31N9O2Purity:100% - 98.87%Color and Shape:SolidMolecular weight:489.57Ref: TM-T10431
2mg96.00€5mg163.00€10mg268.00€25mg465.00€50mg618.00€100mg880.00€1mL*10mM (DMSO)170.00€AZD-2461
CAS:AZD2461 is a novel PARP inhibitor.Formula:C22H22FN3O3Purity:98% - 99.25%Color and Shape:SolidMolecular weight:395.43PRMT5-IN-2
CAS:PRMT5-IN-2 is an inhibitor of protein arginine methyltransferase 5.Formula:C17H16ClFN4O4Purity:98%Color and Shape:SolidMolecular weight:394.78JI069
CAS:JI069 (WAY-354189) is a potent STAT3 inhibitor that inhibits gp130 signaling by inducing dissociation between gp130 and JAK1.Formula:C15H12Cl2N2O4SPurity:98.01%Color and Shape:SolidMolecular weight:387.24
