GPR
G protein-coupled receptors (GPRs) are a large family of cell surface receptors that play a crucial role in transmitting signals from hormones, neurotransmitters, and other extracellular ligands into the cell. GPRs are involved in a wide range of physiological processes, including hormone regulation, immune response, and sensory perception. Modulating GPR activity is a key strategy in the development of therapeutics for various diseases, including endocrine disorders, cardiovascular diseases, and neurological conditions. At CymitQuimica, we offer a selection of high-quality GPR modulators to support your research in cell signaling, endocrinology, and drug discovery.
Products of "GPR"
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GPR41 agonist-1
CAS:GPR41 agonist-1 is a GPR41 agonist, used for studying metabolic diseases such as diabetes and obesity.Formula:C24H23N3O4Purity:98.40%Color and Shape:SolidMolecular weight:417.46AMG-009
CAS:AMG-009 is a prostaglandin D2 antagonist. For CRTH2 and DP receptors, the IC50s are 3 nM and 12 nM, respectively.Formula:C26H26Cl2N2O7SPurity:97.88%Color and Shape:SolidMolecular weight:581.47WAY-298630
CAS:Fluorophenoxy benzimidazole, a CRTH2 blocker, IC50 < 10 μM for rhinitis, COPD, arthritis, eczema, conjunctivitis.Formula:C17H15FN2O3SPurity:97.13%Color and Shape:SolidMolecular weight:346.38Bimatoprost acid
CAS:Bimatoprost acid (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and has a potential antagonistic activity for the FP receptor.Formula:C23H32O5Purity:99.29%Color and Shape:SolidMolecular weight:388.5Ref: TM-T20939
1mg133.00€5mg304.00€10mg452.00€25mg740.00€50mg1,026.00€100mg1,388.00€1mL*10mM (DMSO)325.00€CRTh2 antagonist 1
CAS:CRTh2 antagonist 1 is a CRTh2 antagonist (IC50: 89 nM).Formula:C23H25N3O5SPurity:97.39%Color and Shape:SolidMolecular weight:455.53Ref: TM-T10084
1mg115.00€5mg255.00€10mg374.00€25mg562.00€50mg787.00€100mg1,074.00€500mg2,147.00€1mL*10mM (DMSO)283.00€Questiomycin A
CAS:Questiomycin A: crème fraiche antibiotic with antibacterial, anticancer effects; inhibits GRP78.Formula:C12H8N2O2Purity:98% - 99.07%Color and Shape:SolidMolecular weight:212.2Ginsenoside Rb2
CAS:Ginsenoside Rb2 (Ginsenoside C) found in species of Panax, upregulating GPR120 gene expression.Formula:C53H90O22Purity:99.01% - 99.66%Color and Shape:White PowderMolecular weight:1079.27CAY10595
CAS:CAY10595 is an antagonist of the CRTh2 (DP2) receptor with a Ki of 10 nM.Formula:C20H13Cl2FN2O5Purity:100% - 99.71%Color and Shape:SolidMolecular weight:451.23Latanoprost
CAS:Latanoprost (Xalatan) is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect.Formula:C26H40O5Purity:99.69% - 99.78%Color and Shape:Pale Yellow OilMolecular weight:432.59Ref: TM-T2528
1mg47.00€2mg59.00€5mg88.00€10mg142.00€25mg274.00€50mg408.00€100mg603.00€500mg1,293.00€1mL*10mM (DMSO)87.00€AM-4668
CAS:AM-4668, a GPR40 (FFA1) agonist with oral availability, was optimized to reduce central nervous system (CNS) permeability, and reduced blood glucose level.Formula:C24H19F3N2O4SPurity:100% - 99.92%Color and Shape:SolidMolecular weight:488.48AF64394
CAS:AF64394 is a selective inverse agonist of GPR3(pIC50 : 7.3)Formula:C21H20ClN5OPurity:97.22%Color and Shape:SolidMolecular weight:393.87GPCR agonist-2
CAS:GPCR agonist-2 (4-(Cyclopropylamino)-3-nitrobenzoic acid) is an agonist of the orphan human GPCR GPR109B.Formula:C10H10N2O4Purity:99.94%Color and Shape:SolidMolecular weight:222.2NE 52-QQ57
CAS:NE 52-QQ57 is a selective, and orally available antagonist of GPR4(IC50 : 70 nM),with anti-inflammatory activity.Formula:C24H28N6OPurity:98.63%Color and Shape:SolidMolecular weight:416.52Ref: TM-T11461
1mg73.00€5mg160.00€10mg235.00€25mg394.00€50mg587.00€100mg835.00€1mL*10mM (DMSO)170.00€6-OAU
CAS:6-OAU is a GPR84 agonist, activates it in HEK293 cells with a 105 nM EC50.Formula:C12H21N3O2Purity:99.01% - 99.68%Color and Shape:SolidMolecular weight:239.31Ref: TM-T2036
1mg160.00€2mg215.00€5mg329.00€10mg472.00€25mg753.00€50mg1,074.00€100mg1,444.00€1mL*10mM (DMSO)301.00€TAK-041
CAS:TAK-041 (NBI-1065846) is a potent and selective GPR139 agonist.Formula:C18H15F3N4O3Purity:99.95%Color and Shape:SolidMolecular weight:392.33Ref: TM-T9317
1mg37.00€5mg144.00€10mg225.00€25mg452.00€50mg723.00€100mg1,130.00€200mg1,501.00€1mL*10mM (DMSO)159.00€Grp94 Inhibitor-1
CAS:Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor (IC50 : 2 nM).Formula:C22H28N2O2Purity:97.02%Color and Shape:SolidMolecular weight:352.47BTB09089
CAS:BTB09089 (GPR65 agonist ) is a T cell death-associated gene 8 (TDAG8/GPR65)-specific agonist.BTB09089 induces TDAG8 expression and regulates cytokine productionFormula:C14H12Cl2N4OS2Purity:100%Color and Shape:SoildMolecular weight:387.31Acifran
CAS:Acifran (AY 25712) is an HM74A/GPR109A and GPR109B agonist and displays antihyperlipidemic activity.Formula:C12H10O4Purity:98.65%Color and Shape:SolidMolecular weight:218.21APD597
CAS:APD597 (JNJ-38431055) is a GPR119 agonist, used in the treatment of type 2 diabetes.Formula:C21H29N5O6SPurity:99.63% - 99.78%Color and Shape:SolidMolecular weight:479.55GPR81 agonist 1
CAS:GPR81 agonist 1 is a GPR81 agonist that improves glycaemic control in insulin-resistant mouse models for the study of diabetes and obesity.Formula:C22H30N4O2S2Purity:99.68%Color and Shape:SolidMolecular weight:446.63GPR84 antagonist 8
CAS:GPR84 antagonist 8 is a selective GPR84 antagonist.Formula:C23H23N3O5Color and Shape:SolidMolecular weight:421.45TC-O 9311 free base
CAS:TC-O 9311 is a potent GPR139 agonist.Formula:C20H19N3O4Purity:99.24%Color and Shape:SoildMolecular weight:365.39Ref: TM-T4626
Discontinued productMS 15203
CAS:MS 15203 is a GPR171 agonist that reduces chronic neuropathic and inflammatory pain in male mice.Formula:C12H11NO5Purity:99.53%Color and Shape:SolidMolecular weight:249.22Ref: TM-T37131
2mg46.00€5mg66.00€10mg104.00€25mg210.00€50mg311.00€100mg467.00€500mg1,017.00€1mL*10mM (DMSO)74.00€Setipiprant
CAS:Setipiprant (ACT-129968) is an oral CRTH2 antagonist for asthma/allergy, targeting PGD2-induced inflammation (IC50: 6.0 nM).Formula:C24H19FN2O3Purity:99.16%Color and Shape:SolidMolecular weight:402.42AZ12216052
CAS:AZ12216052 is a GRP8 antagonist with anxiolytic and anti-inflammatory activity and can be used to study obesity and metabolic disorders.Formula:C19H22BrNOSPurity:99.29%Color and Shape:SolidMolecular weight:392.35TAK-875 Hemihydrate
CAS:TAK-875 Hemihydrate (Fasiglifam) is a selective GPR40 agonist with EC50 of 14 nM, 400-fold more potent than oleic acid.Formula:C29H32O7SH2OPurity:98%Color and Shape:SolidMolecular weight:533.63GSK137647A
CAS:GSK137647A (GSK 137647) is a selective FFA4 agonist.Formula:C16H19NO3SPurity:99.26% - 99.87%Color and Shape:SolidMolecular weight:305.39Ref: TM-T3171
2mg35.00€5mg51.00€10mg85.00€25mg155.00€50mg245.00€100mg424.00€200mg613.00€500mg938.00€1mL*10mM (DMSO)57.00€MK 1903
CAS:MK 1903 is a strong, selective HCA2/GPR109A agonist, reducing cAMP in CHO cells with EC50 of 12.9 nM.Formula:C8H8N2O2Purity:99.87%Color and Shape:SolidMolecular weight:164.16VER-155008
CAS:VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively.Formula:C25H23Cl2N7O4Purity:98.88% - 99.55%Color and Shape:SolidMolecular weight:556.4Ref: TM-T7010
2mg47.00€5mg69.00€10mg93.00€25mg163.00€50mg283.00€100mg467.00€200mg653.00€1mL*10mM (DMSO)85.00€ATC 0175 hydrochloride
CAS:ATC 0175 hydrochloride is an orally active melanocyte concentrating hormone 1 receptor antagonist that is potent and selective.Formula:C23H26ClF2N5OPurity:99.84%Color and Shape:SolidMolecular weight:461.93Kuwanon H
CAS:Kuwanon H is a potent non-peptide GRP receptor antagonist with a Ki of 290 nM, useful in GRP-related studies.Formula:C45H44O11Purity:97.99%Color and Shape:SolidMolecular weight:760.821-methoxycyclopropanecarboxylic acid
CAS:1-methoxycyclopropanecarboxylic acid is an agonist of free fatty acid receptor 3 (FFAR3, human).Formula:C5H8O3Purity:99.44%Color and Shape:Light-Yellow To Yellow Solid Or LiquidMolecular weight:116.12GPR35 agonist 2
CAS:GPR35 agonist 2 (TC-G 1001) is a potent GPR35 agonist.The EC50 values of GPR35 agonist 2 in the β-arrestin and Ca2+ release assays were 26 and 3.2 nM,Formula:C17H11FN2O3SPurity:97.18% - 98.40%Color and Shape:SolidMolecular weight:342.34Ref: TM-T23434
1mg52.00€5mg96.00€10mg170.00€25mg378.00€50mg560.00€100mg800.00€500mg1,644.00€1mL*10mM (DMSO)114.00€GPR120 Agonist 1
CAS:GPR120 Agonist 1 selectively activates human/mouse GPR120 with EC50 of 42/77 nM in HEK293 cells.Formula:C20H12ClF6NO3SPurity:98%Color and Shape:SolidMolecular weight:495.823-chloro-5-hydroxybenzoic Acid
CAS:3-chloro-5-hydroxy Benzoic Acid (3-chloro-5-hydroxy BA) is an agonist of GPR81 (EC50 : 16 μM)Formula:C7H5ClO3Purity:98%Color and Shape:SolidMolecular weight:172.57AH-7614
CAS:AH-7614 (AH 7614) is a selective and potent free fatty acid receptor 4 (FFA4/GPR120) antagonist.Formula:C20H17NO3SPurity:98.05%Color and Shape:SolidMolecular weight:351.42Ref: TM-T22027
5mg51.00€10mg90.00€25mg173.00€50mg311.00€100mg424.00€200mg552.00€500mg715.00€1mL*10mM (DMSO)64.00€TUG-1375
CAS:TUG-1375 is an Agonist of Thiazolidine Free Fatty Acid Receptor 2Formula:C22H19ClN2O4SPurity:97.72% - 99.41%Color and Shape:SolidMolecular weight:442.92Ref: TM-T7796
1mg133.00€5mg323.00€10mg527.00€25mg822.00€50mg1,103.00€100mg1,483.00€500mg2,965.00€1mL*10mM (DMSO)354.00€D-Kynurenine
CAS:D-Kynurenine, ZINC901103, metabolizes from D-tryptophan, activates AhR, changes epithelium to mesenchyme, and tests for D-amino acid oxidase.Formula:C10H12N2O3Purity:97.08%Color and Shape:SolidMolecular weight:208.21Kynurenic acid
CAS:Kynurenic acid (Quinurenic acid) is an NMDA, glutamate, α7 nicotinic acetylcholine receptor triple antagonist and GPR35/CXCR8 agonist.Formula:C10H7NO3Purity:99.69%Color and Shape:SolidMolecular weight:189.17PU-H54
CAS:PU-H54 is a purine-derived Grp94 inhibitor targeting the S2 subpocket's unique binding region.Formula:C18H19N5SPurity:99.13%Color and Shape:SolidMolecular weight:337.44Fezagepras sodium
CAS:Fezagepras sodium (Setogepram sodium salt) is an orally active GPR40 agonist and is an antagonist or inverse agonist for GPR84, with anti-fibrotic, anti-Formula:C13H17NaO2Purity:99.59%Color and Shape:SolidMolecular weight:228.26Ref: TM-T12375
1mg43.00€5mg96.00€10mg140.00€25mg255.00€50mg374.00€100mg542.00€500mg1,093.00€1mL*10mM (DMSO)96.00€Palosuran hydrochloride 540769-28-6(free base)
Palosuran hydrochloride 540769-28-6(free base)(ACT-058362 hydrochloride) is a new potent and specific antagonist of the human UT receptor with an IC50 of 3.6±0.Formula:C25H31ClN4O2Purity:99.75%Color and Shape:SolidMolecular weight:454.99Ramatroban
CAS:Ramatroban (BAY u3405) (BAY u3405) is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis.Formula:C21H21FN2O4SPurity:98.12% - 99.96%Color and Shape:Crystalline SolidMolecular weight:416.47Ref: TM-T2396
5mg38.00€10mg57.00€25mg95.00€50mg170.00€100mg274.00€200mg354.00€500mg597.00€1mL*10mM (DMSO)63.00€Ogremorphin
CAS:Ogremorphin (GPR68-IN-1) is a potent inhibitor of GPR68, exhibiting an EC50 of 170 nM.it is utilized in the study of autoimmune chronic inflammatory diseases [1Formula:C21H17N3OSPurity:99.65% - 99.65%Color and Shape:SolidMolecular weight:359.44DJ-V-159
CAS:DJ-V-159 is a GPRC6A agonist, targeting the G protein-coupled receptor family C group 6 member A (GPRC6A).Formula:C24H12F6N4O2Purity:99.85% - 99.96%Color and Shape:SolidMolecular weight:502.37LY2881835
CAS:LY2881835 is a potent and selective GPR40 agonist.Formula:C33H33NO3Purity:97.65% - 97.65%Color and Shape:SolidMolecular weight:491.62APD668
CAS:APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.Formula:C21H24FN5O5SPurity:99.45% - 99.97%Color and Shape:SolidMolecular weight:477.51GPR40/FFAR1 modulator 1
CAS:GPR40/FFAR1 modulator 1 is a Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1) agonist and allosteric modulator.Formula:C21H19N5O3Purity:99.72%Color and Shape:SolidMolecular weight:389.41NOX-6-18
CAS:NOX-6-18 (GPR132-B-160) is a GPR132 antagonist with insulin-promoting activity and reduced weight gain.Formula:C18H17NO5SPurity:99.29%Color and Shape:SoildMolecular weight:359.4hGPR91 antagonist 3
CAS:hGPR91 antagonist 3 is an hGPR91 antagonist. hGPR91 antagonist 3 can be used to study diseases in hypertension and retinal angiogenesis.Formula:C23H18F4N4O2Purity:98.82% - 98.82%Color and Shape:SolidMolecular weight:458.41
