
GPR
G protein-coupled receptors (GPRs) are a large family of cell surface receptors that play a crucial role in transmitting signals from hormones, neurotransmitters, and other extracellular ligands into the cell. GPRs are involved in a wide range of physiological processes, including hormone regulation, immune response, and sensory perception. Modulating GPR activity is a key strategy in the development of therapeutics for various diseases, including endocrine disorders, cardiovascular diseases, and neurological conditions. At CymitQuimica, we offer a selection of high-quality GPR modulators to support your research in cell signaling, endocrinology, and drug discovery.
Products of "GPR"
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CAY10786
CAS:CAY10786 (GPR52 antagonist-1) is an antagonist of G protein-coupled receptor 52 (GPR52, IC50 = 0.63 μM).Formula:C15H14OSPurity:99.84%Color and Shape:SolidMolecular weight:242.34IBC 293
CAS:IBC 293: Selective GPR109B agonist, favoring it over GPR109A; targets receptor in fat cells.Formula:C10H11N3O2Purity:99.63%Color and Shape:SolidMolecular weight:205.21MK-6892
CAS:MK-6892 is a selective and full agonist for the high-affinity nicotinic acid receptor GPR109A (Ki: 4 nM; GTPγS EC50: 16 nM).Formula:C19H22N4O5Purity:99.01% - 99.03%Color and Shape:SolidMolecular weight:386.4Ref: TM-TQ0108
1mg97.00€5mg188.00€10mg283.00€25mg472.00€50mg655.00€100mg944.00€500mg1,882.00€1mL*10mM (DMSO)230.00€MK-7246
CAS:MK-7246 is a potent and specific CRTH2 antagonist (Ki: 2.5 nM).Formula:C21H21FN2O4SColor and Shape:SolidMolecular weight:416.47GW-1100
CAS:GW-1100 is a selective GPR40 and FFAR1 antagonist for the study of diabetes and metabolic diseases.Formula:C27H25FN4O4SPurity:97.01%Color and Shape:SolidMolecular weight:520.58MBX-2982
CAS:MBX-2982 is a selective, orally-available GPR119 agonist, used for the treatment of diabetes.Formula:C22H24N8OSPurity:98% - 99.96%Color and Shape:SolidMolecular weight:448.54Ref: TM-T1793
1mg50.00€5mg106.00€10mg177.00€25mg321.00€50mg487.00€100mg730.00€200mg998.00€1mL*10mM (DMSO)117.00€FL104
CAS:FL104 is a potent agonist of small-molecule urotensin II receptor, pEC50= 7.11.Formula:C24H25ClN2OPurity:99.46%Color and Shape:SolidMolecular weight:392.92Ref: TM-T27328
1mg116.00€5mg273.00€10mg373.00€25mg563.00€50mg758.00€100mg998.00€200mg1,320.00€1mL*10mM (DMSO)333.00€GSK256073
CAS:GSK256073 is an orally active GPR109A agonist.Formula:C10H13ClN4O2Purity:98.03%Color and Shape:SolidMolecular weight:256.69Ref: TM-T15432
1mg73.00€2mg97.00€5mg160.00€10mg250.00€25mg439.00€50mg647.00€100mg920.00€1mL*10mM (DMSO)170.00€AS1269574
CAS:AS1269574 is a potent, orally available GPR119 agonist. AS1269574(AS 1269574) has the potential for the research of type 2 diabetes.Formula:C13H14BrN3OPurity:99.99%Color and Shape:SolidMolecular weight:308.17Ref: TM-T21623
2mg39.00€5mg57.00€10mg96.00€25mg168.00€50mg270.00€100mg406.00€200mg592.00€1mL*10mM (DMSO)66.00€3-Hydroxyoctanoic Acid
CAS:3-Hydroxyoctanoic Acid, an energy metabolism intermediate, activates orphan receptor GPR109B.Formula:C8H16O3Purity:97.82% - ≥98%Color and Shape:SolidMolecular weight:160.21TC-O 9311
CAS:TC-O 9311 (TCO-9311) is an effective agonist of GPR139 (EC50 = 39 nM in CHO-K1 cells expressing human GPR139).Formula:C20H19N3O4Purity:99.24% - 99.84%Color and Shape:SolidMolecular weight:365.38Ref: TM-T4626L
5mg49.00€10mg77.00€25mg134.00€50mg207.00€100mg339.00€200mg480.00€1mL*10mM (DMSO)50.00€Pamoic acid
CAS:Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.Formula:C23H16O6Purity:99.99%Color and Shape:Fine Yellow PowderMolecular weight:388.37CVN424
CAS:CVN424 is a selective and novel GPR6 Inverse agonist effective in models of Parkinson Disease.Formula:C24H29F2N5O3Purity:99.02%Color and Shape:SolidMolecular weight:473.52Ref: TM-T9346
1mg96.00€5mg243.00€10mg376.00€25mg630.00€50mg898.00€100mg1,216.00€1mL*10mM (DMSO)253.00€GLPG1205
CAS:GLPG1205 is a potent, orally active GPR84 (G protein-coupled receptor) antagonist with anti-inflammatory activity.Formula:C22H22N2O4Purity:95.97% - 99.34%Color and Shape:SolidMolecular weight:378.42Ref: TM-T11411
1mg96.00€5mg207.00€10mg354.00€25mg597.00€50mg852.00€100mg1,159.00€1mL*10mM (DMSO)226.00€TUG-891
CAS:TUG-891 is a G protein-coupled receptor expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long chain free fatty acids.Formula:C23H21FO3Purity:98.28% - 99.21%Color and Shape:SolidMolecular weight:364.41Ref: TM-T3433
1mg40.00€2mg51.00€5mg85.00€10mg115.00€25mg225.00€50mg378.00€100mg552.00€500mg1,169.00€1mL*10mM (DMSO)93.00€SNAP 94847
CAS:SNAP 94847 (SNAP-94847) is a selective and competitive MCH1 receptor (MCH1-R) antagonist (Ki: 2.2 nM).Formula:C29H32F2N2O2Purity:98%Color and Shape:SolidMolecular weight:478.57CAY10471 Racemate
CAS:CAY10471 Racemate is a potent CRTH2/DP2 antagonist with Ki of 0.6 nM; less active on DP1 and TP.Formula:C21H21FN2O4SPurity:99.08%Color and Shape:SolidMolecular weight:416.47BMS-903452
CAS:BMS-903452: potent GPR119 agonist, EC50 = 14 nM, treats rodent diabetes, no P450 inhibition, safe for liver cells.Formula:C21H19Cl2FN4O4SPurity:100% - 100%Color and Shape:SolidMolecular weight:513.37Ref: TM-T67791
1mg90.00€5mg220.00€10mg311.00€25mg469.00€50mg632.00€100mg855.00€200mg1,121.00€1mL*10mM (DMSO)258.00€Vincamine
CAS:Vincamine, from Vinca minor, is an alkaloid used as a vasodilator and antihypertensive for brain circulation issues.Formula:C21H26N2O3Purity:98.96%Color and Shape:White To Almost White Fine Crystalline PowderMolecular weight:354.44GPR4 antagonist 1
CAS:GPR4 antagonist 1 is a GPR4 antagonist (IC50: 189 nM).Formula:C27H37N5Purity:98%Color and Shape:SolidMolecular weight:431.62