GPR
G protein-coupled receptors (GPRs) are a large family of cell surface receptors that play a crucial role in transmitting signals from hormones, neurotransmitters, and other extracellular ligands into the cell. GPRs are involved in a wide range of physiological processes, including hormone regulation, immune response, and sensory perception. Modulating GPR activity is a key strategy in the development of therapeutics for various diseases, including endocrine disorders, cardiovascular diseases, and neurological conditions. At CymitQuimica, we offer a selection of high-quality GPR modulators to support your research in cell signaling, endocrinology, and drug discovery.
Products of "GPR"
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Fezagepras
CAS:Fezagepras (Setogepram) is an orally active GPR40 agonist and is an antagonist or inverse agonist of GPR84 with anti-inflammatory, anti-fibrotic, and anti-Formula:C13H18O2Purity:96.73% - 99.38%Color and Shape:SolidMolecular weight:206.28Ref: TM-T12883
1mg52.00€2mg74.00€5mg96.00€10mg140.00€25mg245.00€50mg350.00€100mgTo inquire1mL*10mM (DMSO)93.00€PU-WS13 hydrobromide
PU-WS13 hydrobromide is a GRP94 inhibitor with anti-inflammatory activity and inhibits the proliferation of M2-like macrophages in mouse TNBC tumors.Formula:C17H21BrCl2N6SPurity:98.63%Color and Shape:SoildMolecular weight:492.26MS21570
CAS:MS21570 as a GPR171 antagonist based on its ability to block,with an IC50 of 220 Nm,that reduces anxiety-like behavior and fear conditioning in mice.Formula:C10H11N3S2Purity:97.79%Color and Shape:SolidMolecular weight:237.34BI-671800
CAS:BI-671800 (AP-761) is a DP2/CRTH2 antagonist with IC50 values of 4.5 nM and 3.7 nM, potential for treating asthma.Formula:C25H26F3N5O3Purity:99.19%Color and Shape:SolidMolecular weight:501.5Ref: TM-T14565
1mg58.00€5mg131.00€10mg207.00€25mg373.00€50mg530.00€100mg718.00€200mg938.00€1mL*10mM (DMSO)144.00€(1S,2R)-2-PCCA
(1S,2R)-2-PCCA is a novel and potent small molecule GPR88 receptor agonist with an EC50 value of 3 nM in the non-cellular system and 603 nM in the cellularFormula:C30H39Cl2N3OPurity:99.34%Color and Shape:SoildMolecular weight:528.56AZD1981
CAS:AZD1981: selective CRTh2 antagonist, IC50 4 nM, 1000x specificity over 340+ enzymes/receptors, tested in asthma and other trials.Formula:C19H17ClN2O3SPurity:98.59% - 99.54%Color and Shape:SolidMolecular weight:388.872-Oleoylglycerol
CAS:2-Oleoylglycerol is a lipid found in palm kernels that acts as a GPR119 agonist with neuroprotective properties and can be used in steatohepatitis modeling.Formula:C21H40O4Purity:98%Color and Shape:SolidMolecular weight:356.54FTBMT
CAS:FTBMT is a selective GPR52 agonist (EC50: 75 nM) and it also has antipsychotic and procognitive properties.Formula:C19H16F4N4OPurity:99.12%Color and Shape:SolidMolecular weight:392.35Ref: TM-T15352
5mg52.00€10mg85.00€25mg170.00€50mg301.00€100mg469.00€200mg620.00€1mL*10mM (DMSO)52.00€MEDICA16
CAS:MEDICA16: GPR40 agonist, GPR120 partial agonist, ATP-citrate lyase inhibitor, lowers TG, boosts insulin sensitivity in muscle.Formula:C20H38O4Purity:99.13% - 99.85%Color and Shape:White SolidMolecular weight:342.51GLPG0974
CAS:GLPG0974 is an antagonist of FFA2/GPR43 with IC50 of 9 nM.Formula:C25H25ClN2O4SPurity:99.58%Color and Shape:SolidMolecular weight:484.99AM-1638
CAS:AM-1638 is an orally active GPR40/FFA1 agonist, useful for studying type II diabetes.Formula:C33H35FO4Color and Shape:SolidMolecular weight:514.63Timapiprant
CAS:Timapiprant (OC000459) is a potent and selective D prostanoid receptor 2 (DP2) antagonist (IC50: 13 nM).Formula:C21H17FN2O2Purity:98.4% - 99.51%Color and Shape:SolidMolecular weight:348.37Benzyl nicotinate
CAS:Benzyl nicotinate (Pycaril) is a agonist of GPR109A receptor and GPR109B receptorFormula:C13H11NO2Purity:98.22%Color and Shape:Yellow LiquidMolecular weight:213.23SNAP 94847 hydrochloride
CAS:SNAP 94847 hydrochloride is a melanin-concentrating hormonereceptor1 (MCHR1) antagonist(Ki= 2.2 nM)Formula:C29H33ClF2N2O2Purity:100% - 99.85%Color and Shape:SolidMolecular weight:515.03Ref: TM-T8004
2mg42.00€5mg64.00€10mg97.00€25mg187.00€50mg316.00€100mg455.00€200mg635.00€1mL*10mM (DMSO)71.00€Fevipiprant
CAS:Fevipiprant (NVP-QAW039) is a selective, potent, reversible competitive CRTh2 antagonist.Formula:C19H17F3N2O4SPurity:99.32% - 99.59%Color and Shape:SolidMolecular weight:426.41(+/-)-Pinocembrin
CAS:(+/-)-Pinocembrin (NSC-43318), a natural product from axillary pines, is a GPR120 ligand that promotes wound healing in the HaCaT cell line.Formula:C15H12O4Purity:99.79%Color and Shape:SolidMolecular weight:256.25Dihydromunduletone
CAS:Dihydromunduletone (DHM) is an adhesion G protein-coupled receptor (aGPCR) antagonist inhibits GPR56 and GPR114/ADGRG5, which have similar tethered agonists.Formula:C25H28O6Purity:99.96%Color and Shape:SolidMolecular weight:424.49TUG-499
CAS:TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) agonist (EC50: 7.39).TUG-499 has an affinity for FFAR1 or GPR40 over the related receptorsFormula:C16H11Cl2NO2Purity:99.59%Color and Shape:SoildMolecular weight:320.17Ref: TM-T60184
1mg35.00€5mg74.00€10mg97.00€25mg164.00€50mg212.00€100mg279.00€200mg395.00€1mL*10mM (DMSO)78.00€NF-56-EJ40
CAS:NF-56-EJ40 is an effective and highly selective antagonist of human SUCNR1 with an IC50 of 25 nM and a Ki of 33 nM.Formula:C27H29N3O3Purity:99.51%Color and Shape:SolidMolecular weight:443.54Monomethyl fumarate
CAS:Monomethyl fumarate is a potent agonist of GPR109A .Formula:C5H6O4Purity:99.21%Color and Shape:SolidMolecular weight:130.1
