NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Products of "NF-κB"
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Aconine
CAS:1. Aconine (Jesaconine) is the febrifuge. 2. Aconine possesses gastric anaesthetic props.Formula:C25H41NO9Purity:99.43% - 99.61%Color and Shape:SolidMolecular weight:499.59AS-2444697
CAS:AS-2444697, an IRAK-4 inhibitor (C50=21 nM), offers renal protection via anti-inflammatory effects on human and rat IRAK-4.Formula:C19H21ClN6O4Purity:97.43%Color and Shape:SolidMolecular weight:432.86Lidocaine hydrochloride
CAS:Lidocaine HCl: local anesthetic, antiarrhythmic, stronger & longer-lasting than procaine but shorter than bupivacaine/prilocaine.Formula:C14H23ClN2OPurity:99.81% - 99.92%Color and Shape:White Crystal PowderMolecular weight:270.798WEHI-345
CAS:WEHI-345 is a potent and selective RIPK2 inhibitor which shows NOD signalling events yet prevents inflammatory cytokine production.Formula:C22H23N7OPurity:100%Color and Shape:SolidMolecular weight:401.46Cpd27
CAS:Cpd27 (TIE-2/VEGFR-2 kinase-IN-2) is a TIE-2 and VEGFR-2 inhibitor that inhibits RIPK1 and can be used to study glaucoma.Formula:C20H13F4N5O2Purity:98.89%Color and Shape:SolidMolecular weight:431.34TBK1/IKKε-IN-1
CAS:TBK1/IKKε-IN-1 is a dual inhibitor of TBK1 and IKKε (IC50s of <100 nM).Formula:C28H26N4O5Purity:98%Color and Shape:SolidMolecular weight:498.53Vinpocetine
CAS:Vinpocetine (RGH-4405) is a selective inhibitor of cyclic GMP phosphodiesterase (PDE).Formula:C22H26N2O2Purity:99.85% - 99.98%Color and Shape:White Crystalline SolidMolecular weight:350.45IRAK inhibitor 2
CAS:IRAK inhibitor 2 (IRAK-IN-2) is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK-4) for the study of inflammation-related diseases.Formula:C17H14N4O2Purity:97.62% - 99.26%Color and Shape:SolidMolecular weight:306.32Ref: TM-T7368
1mg86.00€5mg180.00€10mg259.00€25mg455.00€50mg655.00€100mg938.00€500mg1,882.00€1mL*10mM (DMSO)188.00€LTβR-IN-1
CAS:LTβR-IN-1 is a potent and selective lymphin β receptor (LTβR) inhibitor.Formula:C18H16N4O2Purity:99.09%Color and Shape:SolidMolecular weight:320.35Ref: TM-T11886
1mg35.00€5mg80.00€10mg116.00€25mg220.00€50mg328.00€100mg469.00€500mg938.00€1mL*10mM (DMSO)87.00€yangonin
CAS:Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.Formula:C15H14O4Purity:98.82% - 99.55%Color and Shape:Pale Yellow PowderMolecular weight:258.27Ref: TM-T3S0738
1mg70.00€5mg135.00€10mg207.00€25mg349.00€50mg515.00€100mg735.00€1mL*10mM (DMSO)177.00€Sulfasalazine
CAS:Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.Formula:C18H14N4O5SPurity:98.00% - 99.28%Color and Shape:Minute Brownish-Yellow CrystalsMolecular weight:398.39Tryptanthrin
CAS:Tryptanthrin is a natural DNA gyrase inhibitor.Formula:C15H8N2O2Purity:99.64% - 99.94%Color and Shape:SolidMolecular weight:248.24GS143
CAS:GS143 inhibits IκBα ubiquitination (IC50=5.2μM), suppresses NF-κB, and has anti-asthma properties without hindering proteasomes.Formula:C28H19FN2O4Purity:99.72%Color and Shape:SolidMolecular weight:466.46Ref: TM-T25465
2mg38.00€5mg58.00€10mg92.00€25mg170.00€50mg259.00€100mg378.00€200mg548.00€1mL*10mM (DMSO)60.00€Dimethoxycurcumin
CAS:Dimethoxycurcumin is a stable curcumin analog causing epigenetic shifts in leukemia cells, affecting gene expression.Formula:C23H24O6Purity:96.05%Color and Shape:SolidMolecular weight:396.43Ref: TM-T19853
5mg50.00€10mg81.00€25mg140.00€50mg239.00€100mg349.00€200mg497.00€1mL*10mM (DMSO)56.00€BMS-345541
CAS:BMS-345541 (IKK Inhibitor III) is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.Formula:C14H17N5Purity:98.74% - 99.74%Color and Shape:SolidMolecular weight:255.32Licochalcone D
CAS:Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.Formula:C21H22O5Purity:99.03% - 99.9%Color and Shape:SolidMolecular weight:354.4SM-7368
CAS:The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.Formula:C10H5ClN4O5SPurity:99.64% - 99.64%Color and Shape:SolidMolecular weight:328.69Ref: TM-T22115
5mg47.00€10mg74.00€25mg135.00€50mg188.00€100mg283.00€200mg411.00€1mL*10mM (DMSO)50.00€Picroside II
CAS:Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.Formula:C23H28O13Purity:98% - 99.83%Color and Shape:SolidMolecular weight:512.46NF-κB-IN-13
CAS:NF-κB-IN-13 (compound 12) markedly suppresses LPS-induced NF-κB activation and NO synthesis in RAW264.7 macrophages, exhibiting anti-inflammatory properties [1Formula:C20H20O5Purity:98%Color and Shape:SolidMolecular weight:340.37
