NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Products of "NF-κB"
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Chelidonic acid
CAS:Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.Formula:C7H4O6Purity:99.03%Color and Shape:SolidMolecular weight:184.1Cyclo(his-pro)
CAS:Cyclo(his-pro) is a cyclic dipeptide that shields against oxidative damage by activating Nrf2.Formula:C11H14N4O2Purity:99.87%Color and Shape:SolidMolecular weight:234.25Tripeptide-41
CAS:Tripeptide-41 (CG-Lipoxyn) is a bioactive peptide known for its ability to reduce fat accumulation.Formula:C29H30N4O5Purity:98%Color and Shape:SolidMolecular weight:514.57Zabedosertib
CAS:Zabedosertib (BAY 1834845) is an inhibitor of IRAK4 with immunomodulatory potential.Formula:C20H21F3N4O4SPurity:98.48%Color and Shape:SolidMolecular weight:470.47Ref: TM-T37076
1mg43.00€5mg96.00€10mg135.00€25mg220.00€50mg323.00€100mg450.00€500mgTo inquire1mL*10mM (DMSO)96.00€NF-κB-IN-11
CAS:NF-κB-IN-11 (Compound 3i) is an inhibitor of NF-κB, effectively blocking TNF-α-induced NF-κB pathway activation and the nuclear translocation of NF-κB.Formula:C19H18O5Purity:98%Color and Shape:SolidMolecular weight:326.34Kamebakaurin
CAS:Kamebakaurin combats liver toxicity, cancer, inflammation, and neuroinflammation by blocking NF-κB, HIF-1α, and key signaling pathways.Formula:C20H30O5Purity:98.05%Color and Shape:SolidMolecular weight:350.45NIK-IN-2
CAS:NIK-IN-2 (compound 1) is an effective inhibitor of NF-κB inducing kinase (NIK), exhibiting a pIC50 of 7.4. It plays a crucial role in cancer research.Formula:C20H22N4O3Color and Shape:SolidMolecular weight:366.41CAY10575
CAS:CAY10575 (IKK2-IN-3) is a potent IKK2 inhibitor with potential anti-inflammatory activity for the study of inflammatory and endocrine diseases.Formula:C22H21N3O6S2Color and Shape:SolidMolecular weight:487.55Zharp2-1
CAS:Zharp2-1 is a RIPK2 inhibitor that alleviates MDP-induced peritonitis symptoms in mice and can be used to study inflammatory bowel disease (IBD).Formula:C19H18N3O2PSPurity:99.41%Color and Shape:SolidMolecular weight:383.4Prostratin
CAS:Prostratin is an orally active PKC activator,an NF-κB activator and activates HIV expression. Induces KRAS phosphorylation and inhibits tumor growth.Formula:C22H30O6Purity:98%Color and Shape:White To Off-White PowderMolecular weight:390.47Baicalin
CAS:Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIVFormula:C21H18O11Purity:90.08% - 99.25%Color and Shape:Yellow PowderMolecular weight:446.36CAFESTOL
CAS:Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.Formula:C20H28O3Purity:97.06% - 99.08%Color and Shape:SolidMolecular weight:316.43NFATc1-IN-1
CAS:NFATc1-IN-1 (A04) inhibits RANKL-induced osteoclast formation with 1.57 μM IC50, blocking NFATc1 translocation.Formula:C13H8F2INO2Purity:99.64%Color and Shape:SolidMolecular weight:375.11Cyclo(L-Pro-L-Val)
CAS:Cyclo(L-Pro-L-Val), from Mycobacterium spp., has anti-inflammatory effects, hinders phytopathogens, and suppresses IKKα, NF-κB, iNOS, and COX-2 activation.Formula:C10H16N2O2Purity:98.18%Color and Shape:SolidMolecular weight:196.25CDDO-dhTFEA
CAS:CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor.Formula:C33H45F3N2O3Purity:95.61% - 99.59%Color and Shape:SolidMolecular weight:574.72Ref: TM-T13604
1mg70.00€2mg92.00€5mg153.00€10mg255.00€25mg512.00€50mg738.00€100mg1,035.00€500mg2,062.00€1mL*10mM (DMSO)187.00€Rucaparib
CAS:Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.Formula:C19H18FN3OPurity:98.37% - 99.80%Color and Shape:SolidMolecular weight:323.36Ref: TM-T4463
2mg48.00€5mg73.00€10mg115.00€25mg173.00€50mg235.00€100mg364.00€200mg540.00€500mg869.00€1mL*10mM (DMSO)81.00€SC75741
CAS:SC75741 is a potent P65 inhibitor with IC50 of 200 nMFormula:C29H23N7O2S2Purity:99.44% - 99.82%Color and Shape:SolidMolecular weight:565.67Edecesertib
CAS:Edecesertib (GS 5718) is an IRAK-4 inhibitor with anti-inflammatory activity for the study of rheumatoid arthritis.Formula:C22H22FN7O2Purity:98.84%Color and Shape:SolidMolecular weight:435.45ANTHRAQUINONE-2-CARBOXYLIC ACID
CAS:Anthraquinone-2-carboxylic acid acts as a potent anti-inflammatory and antinociceptive component in vivo, thus contributing to the immune regulatory role ofFormula:C15H8O4Purity:99.08% - 99.83%Color and Shape:SolidMolecular weight:252.22Rocaglamide
CAS:Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.Formula:C29H31NO7Purity:95.32% - 98.46%Color and Shape:SolidMolecular weight:505.56
