NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Products of "NF-κB"
Sort by
Avicularin
CAS:Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.Formula:C20H18O11Purity:97.02% - 99.94%Color and Shape:White PowderMolecular weight:434.35Ref: TM-T6S0117
1mg58.00€5mg97.00€10mg160.00€25mg283.00€50mg418.00€100mg615.00€200mg878.00€1mL*10mM (DMSO)111.00€Sinomenine hydrochloride
CAS:Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.Formula:C19H24ClNO4Purity:99.43%Color and Shape:SolidMolecular weight:365.851(R)-(-)-Ibuprofen
CAS:(R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation.Formula:C13H18O2Purity:99.47%Color and Shape:SolidMolecular weight:206.28Bay 65-1942 hydrochloride
CAS:Bay 65-1942 hydrochloride is an inhibitor of ATP-competitive and selective IKKβ.Formula:C22H26ClN3O4Color and Shape:SolidMolecular weight:431.91Kaempferol-3-O-glucorhamnoside
CAS:Kaempferol-3-O-glucorhamnoside (Kaempferol 3-glucorhamnoside), a flavonoid derived from plant Thesium chinense Turcz, inhibits inflammatory responses via MAPKFormula:C27H30O15Purity:96.96% - 98.17%Color and Shape:SolidMolecular weight:594.5Ref: TM-T5S0089
1mg50.00€5mg97.00€10mg143.00€25mg226.00€50mg340.00€100mg495.00€200mg682.00€1mL*10mM (DMSO)129.00€Berbamine dihydrochloride
CAS:Berbamine dihydrochloride (Berbamine), a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.Formula:C37H42Cl2N2O6Purity:95% - 99.38%Color and Shape:SolidMolecular weight:681.65Dauricine
CAS:1.Formula:C38H44N2O6Purity:99.04% - 99.38%Color and Shape:White PowderMolecular weight:624.77JH-X-119-01
CAS:JH-X-119-01 is a highly potent and selective covalent inhibitor of IRAK-1.Formula:C25H20N6O3Purity:97.1%Color and Shape:SolidMolecular weight:452.46Ref: TM-T9203
1mg66.00€2mg96.00€5mg144.00€10mg210.00€25mg376.00€50mg562.00€100mg780.00€1mL*10mM (DMSO)159.00€Diethylmaleate
CAS:Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.Formula:C8H12O4Purity:98%Color and Shape:Colourless LiquidMolecular weight:172.1818α-Glycyrrhetinic acid
CAS:18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.Formula:C30H46O4Purity:98.54% - 99.68%Color and Shape:SolidMolecular weight:470.68Tenuigenin
CAS:Tenuigenin (Senegenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.Formula:C30H45ClO6Purity:98.9% - 99.53%Color and Shape:SolidMolecular weight:537.13Ref: TM-T3907
2mg37.00€5mg52.00€10mg77.00€25mg111.00€50mg160.00€100mg227.00€200mg335.00€1mL*10mM (DMSO)66.00€RIPK1-IN-7
CAS:RIPK1-IN-7: Strong, selective RIPK1 inhibitor (Kd=4 nM, IC50=11 nM) with great antimetastasis effects in B16 melanoma.Formula:C25H22F3N5O2Purity:98.02% - 98.18%Color and Shape:SolidMolecular weight:481.47Ref: TM-T12731
1mg92.00€5mg216.00€10mg329.00€25mg512.00€50mg707.00€100mg944.00€1mL*10mM (DMSO)233.00€Sciadopitysin
CAS:Sciadopitysin may thwart diabetic bone disease, boost mitochondria, protect osteoblasts, and hinder Aβ aggregation/neurotoxicity.Formula:C33H24O10Purity:98.14% - 99.17%Color and Shape:SolidMolecular weight:580.54Ref: TM-T5S2129
1mg52.00€5mg95.00€10mg162.00€25mg304.00€50mg455.00€100mg653.00€500mg1,349.00€1mL*10mM (DMSO)130.00€Sarsasapogenin
CAS:Sarsasapogenin (Parigenin) is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin.Formula:C27H44O3Purity:90% - 99.73%Color and Shape:White Or Off-Withe PowderMolecular weight:416.64MLN120B
CAS:MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).Formula:C19H15ClN4O2Purity:98.92%Color and Shape:SolidMolecular weight:366.8Ref: TM-TQ0306
1mg49.00€2mg70.00€5mg96.00€10mg160.00€25mg329.00€50mg567.00€100mg777.00€1mL*10mM (DMSO)116.00€DRI-C21045
CAS:Dri-c21045 inhibits NF-kB (IC50=17.1μM) and B cell proliferation (IC50=4.5μM), selectively blocking CD40-CD40L interaction (IC50=0.17μM).Formula:C32H24N2O7SPurity:98.10%Color and Shape:SolidMolecular weight:580.61IQ-1S free acid
CAS:IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity.Formula:C15H9N3OPurity:97.92% - 99.05%Color and Shape:SolidMolecular weight:247.25Ref: TM-T3627
5mg47.00€10mg52.00€25mg96.00€50mg169.00€100mg304.00€200mg454.00€500mg733.00€1mL*10mM (DMSO)50.00€NF-κΒ activator 1
CAS:NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.Formula:C16H11FN2O2SPurity:98.85%Color and Shape:SolidMolecular weight:314.33Ref: TM-T39965
1mg95.00€5mg202.00€10mg329.00€25mg560.00€50mg800.00€100mg1,103.00€500mg2,213.00€1mL*10mM (DMSO)224.00€Dehydrocostus Lactone
CAS:Dehydrocostus Lactone ((-)-Dehydrocostus lactone) shows anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties.Formula:C15H18O2Purity:99.86% - 99.98%Color and Shape:SolidMolecular weight:230.3Theophylline monohydrate
CAS:Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calciumFormula:C7H8N4O2·H2OPurity:99.78%Color and Shape:SolidMolecular weight:198.18
