NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Products of "NF-κB"
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Tyloxapol
CAS:Tyloxapol (Triton WR1339) is a non-ionic liquid polymer used as a surfactant.Formula:C70H124O13Purity:polymer - polymerColor and Shape:Clear Light Yellow Viscous LiquidMolecular weight:137.18Ref: TM-T6S1371
1mg52.00€5mg97.00€10mg140.00€25mg274.00€50mg411.00€100mg597.00€500mg1,225.00€1mL*10mM (DMSO)105.00€Demethyleneberberine
CAS:Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria eitherFormula:C19H18NO4Purity:98.08% - 99.18%Color and Shape:SolidMolecular weight:324.35Theaflavin 3,3'-digallate
CAS:Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancerFormula:C43H32O20Purity:98.71% - 99.86%Color and Shape:SolidMolecular weight:868.7Ocadusertib
CAS:Ocadusertib is an effective inhibitor of the serine/threonine kinase receptor-interacting protein kinase 1 (RIPK1).Formula:C25H25N5O4Color and Shape:SolidMolecular weight:459.50Eclitasertib
CAS:Eclitasertib is a potent inhibitor of receptor-interacting protein kinase 1 (RIPK1, IC50 of <1 µΜ).Formula:C19H18N6O3Purity:99.82%Color and Shape:SolidMolecular weight:378.38Ref: TM-T9702
1mg106.00€2mg150.00€5mg227.00€10mg359.00€25mg652.00€50mg905.00€100mg1,293.00€1mL*10mM (DMSO)250.00€BX795
CAS:BX795 selectively inhibits PDK1 (IC50: 6 nM), 140x over PKA, 1600x over PKC, 100x over GSK3β in cell-free assays.Formula:C23H26IN7O2SPurity:98% - 99.57%Color and Shape:SolidMolecular weight:591.47Ref: TM-T1830
5mg59.00€10mg97.00€25mg210.00€50mg343.00€100mg513.00€200mg740.00€500mg1,121.00€1mL*10mM (DMSO)88.00€CL075
CAS:CL075 (3M002) is a selective TLR8 agonist.CL075 has immunomodulatory activity by triggering the MyD88-dependent signaling pathway, activating NF-κB and IRF7 toFormula:C13H13N3SPurity:99.25%Color and Shape:SolidMolecular weight:243.33Flaconitine
CAS:Flaconitine (Acetylaconitine) is an NF-κB inhibitor and an alkaloid.Formula:C36H49NO12Purity:98% - 99.84%Color and Shape:SolidMolecular weight:687.77Flavanomarein
CAS:Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.Formula:C21H22O11Purity:97.53% - 98.63%Color and Shape:SolidMolecular weight:450.39Ginsenoside Re
CAS:Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.Formula:C48H82O18Purity:100% - 99.78%Color and Shape:White PowderMolecular weight:947.15B022
CAS:B022 is an NF-κB-induced kinase (NIK) inhibitor that protects the liver from inflammation and injury caused by oxidative stress and toxins.Formula:C19H16ClN5OSPurity:99.74%Color and Shape:SolidMolecular weight:397.88Mitogen-activated protein kinase 1
CAS:Mitogen-activated protein kinase 1 (MAPK1) activates the p38/NF-κB pathway and regulates cellular processes in sepsis-associated diseases.Purity:98%Color and Shape:SolidRIPK1-IN-9
CAS:RIPK1-IN-9, a potent dihydronaphthone, selectively inhibits RIPK1 with IC50 of 2 nM (U937) and 1.3 nM (L929).Formula:C26H25FN6O2Purity:98.7%Color and Shape:SolidMolecular weight:472.51Ref: TM-T63055
1mg205.00€5mg495.00€10mg677.00€25mg1,008.00€50mg1,349.00€100mg1,833.00€200mg2,452.00€1mL*10mM (DMSO)568.00€Gossypin
CAS:Gossypin exhibits multiple medicinal properties and inhibits NF-kappaB, reducing inflammation, cancer growth, and angiogenesis.Formula:C21H20O13Purity:97.57% - 98.97%Color and Shape:SolidMolecular weight:480.38NLRP3-IN-10
CAS:NLRP3-IN-10 (ZVN26391) is a strong NLRP3 inhibitor, IC50 251.1 nM, that reduces IL-1β and ASC speck, hindering inflammasome activation.Formula:C17H14BrFO3Purity:99.63%Color and Shape:SolidMolecular weight:365.19Ref: TM-T61392
5mg47.00€10mg70.00€25mg126.00€50mg187.00€100mg311.00€200mg465.00€1mL*10mM (DMSO)65.00€2,4-Diamino-6-hydroxypyrimidine
CAS:2,4-Diamino-6-hydroxypyrimidine (DAHP) (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesisFormula:C4H6N4OPurity:99.82%Color and Shape:White Solid CrystalsMolecular weight:126.12NLRP3-IN-11
CAS:NLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism.Formula:C17H17ClN4O2Purity:100%Color and Shape:SolidMolecular weight:344.8GSK2983559 active metabolite
CAS:GSK2983559 active metabolite (RIPK2-IN-1) is a potent, selective receptor-interacting protein-2 (RIP2) kinase inhibitor.Formula:C21H22N4O4S2Purity:97.07% - 98.48%Color and Shape:SolidMolecular weight:458.55Convallatoxin
CAS:Convallatoxin is a natural product.Formula:C29H42O10Purity:99.27%Color and Shape:Prisms From Methanol + Ether SolidMolecular weight:550.64
