NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Products of "NF-κB"
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IVMT-Rx-3
IVMT-Rx-3 is a chemical compound that serves as an inhibitor of SDCBP's targeting of the PDZ1 and PDZ2 domains of MDA-9/Syntenin.Formula:C69H90F3N13O24Purity:98%Color and Shape:SoildMolecular weight:1542.54Sauchinone
CAS:Sauchinone: Treats infections, prevents liver fibrosis, reduces oxidative stress, and protects skin and vascular cells.Formula:C20H20O6Purity:100%Color and Shape:SolidMolecular weight:356.37Gypenoside L
CAS:Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release.Formula:C42H72O14Purity:99.42% - 99.65%Color and Shape:SolidMolecular weight:801.01GSK840
CAS:GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds the RIP3 kinase domain (IC50: 0.9 nM), and inhibits kinaseFormula:C21H23N3O3Purity:99.48%Color and Shape:SolidMolecular weight:365.43Flizasertib
CAS:Flizasertib is a serine/threonine kinase inhibitor that acts by inhibiting RIPK1, which has anti-inflammatory and therapeutic effects on immune disorders.Formula:C15H14FN3OPurity:100% - 99.39%Color and Shape:SolidMolecular weight:271.29Adelmidrol
CAS:Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.Formula:C13H26N2O4Purity:99.35% - 99.73%Color and Shape:SolidMolecular weight:274.36Eudebeiolide B
CAS:Eudebeiolide B, isolated from Salvia plebeia R.Formula:C15H18O4Purity:98%Color and Shape:SolidMolecular weight:262.3Tizoxanide
CAS:Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.Formula:C10H7N3O4SPurity:98.89% - 99.28%Color and Shape:SolidMolecular weight:265.25BOT-64
CAS:BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathioleFormula:C15H15NO2SPurity:99.73%Color and Shape:SolidMolecular weight:273.35Ref: TM-T8705
1mg52.00€5mg116.00€10mg178.00€25mg340.00€50mg520.00€100mg702.00€200mg944.00€1mL*10mM (DMSO)107.00€BMS-066
CAS:BMS-066 is an IKKβ/Tyk2 pseudokinase inhibitor. With IC50s of 9 nM and 72 nM, respectively.Formula:C19H21N7O2Purity:98%Color and Shape:SolidMolecular weight:379.42Robinin
CAS:Robinin: a kaempferol-derived flavone glycoside with antibacterial, diuretic traits; minimal effect on Colo 320 MDR1/LRP resistance; detected in MCF-7 cells.Formula:C33H40O19Purity:98.78% - 99.13%Color and Shape:SolidMolecular weight:740.66IMD-biphenylB
CAS:IMD-biphenylB: Potent NF-κB inhibitor, curbs tumor growth with low inflammation and toxicity.Formula:C35H33N5O3Purity:98%Color and Shape:SolidMolecular weight:571.67Usnoflast
CAS:Usnoflast (ZYIL1) is an NLRP3 inhibitor, inhibiting NLRP3 inflammasome activation, used in neurological disease research.Formula:C21H29N3O3SPurity:98.79%Color and Shape:SolidMolecular weight:403.54AP-1/NF-κB activation inhibitor 1
CAS:AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation ( IC 50 =1 μM), does not blocking basalFormula:C13H11F3N4O4Purity:100% - 99.74%Color and Shape:SolidMolecular weight:344.25Ref: TM-T9656
1mg73.00€2mg96.00€5mg160.00€10mg216.00€25mg354.00€50mg525.00€100mg730.00€500mg1,483.00€1mL*10mM (DMSO)170.00€Edasalonexent
CAS:Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor for the improvement of Duchenne muscular dystrophy.Formula:C31H42N2O3Purity:100% - 98.69%Color and Shape:SolidMolecular weight:490.68Ref: TM-T15198
1mg99.00€2mg144.00€5mg235.00€10mg376.00€25mg677.00€50mg1,064.00€1mL*10mM (DMSO)254.00€HS271
CAS:HS271 is a selective, highly potent and orally active IRAK4 inhibitor (IC50= 7.2 μM).Formula:C21H24F3N5O2Purity:98.12%Color and Shape:SolidMolecular weight:435.44Ref: TM-T37082
1mg62.00€2mg89.00€5mg135.00€10mg212.00€25mg368.00€50mg510.00€100mg695.00€200mg937.00€1mL*10mM (DMSO)149.00€5-Aminosalicylic Acid
CAS:5-ASA, an anti-inflammatory salicylate, treats inflammatory bowel disease, active part of sulphalazine.Formula:C7H7NO3Purity:98.88% - 99.98%Color and Shape:Purplish-Tan Solid PowderMolecular weight:153.14Cornuside
CAS:Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.Formula:C24H30O14Purity:100% - 99.57%Color and Shape:SolidMolecular weight:542.49Ref: TM-T4S2326
1mg96.00€5mg264.00€10mg415.00€25mg677.00€50mg935.00€100mg1,254.00€500mg2,527.00€1mL*10mM (DMSO)315.00€Isoquercetin
CAS:1.Formula:C21H20O12Purity:98.08% - 99.29%Color and Shape:SolidMolecular weight:464.38Ref: TM-T5S0754
5mg49.00€10mg65.00€25mg97.00€50mg153.00€100mg221.00€200mg329.00€1mL*10mM (DMSO)50.00€Isoliquiritin apioside
CAS:Isoliquiritin apioside, from Glycyrrhizae radix, inhibits MMP9, MAPK, NF-κB, reduces cancer cell invasion, angiogenesis, and fights oxidative DNA damage.Formula:C26H30O13Purity:98.84% - 99.27%Color and Shape:SolidMolecular weight:550.51
