NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Products of "NF-κB"
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JSH-23
CAS:JSH-23 is an NF-κB inhibitor that inhibits NF-κB transcriptional activity without affecting IκB degradation. JSH-23 is an antioxidant. Cost effective and quality assured.Formula:C16H20N2Purity:98.03% - 99.67%Color and Shape:SolidMolecular weight:240.34Ref: TM-T1930
1mg43.00€2mg57.00€5mg93.00€10mg119.00€25mg187.00€50mg283.00€100mg430.00€1mL*10mM (DMSO)93.00€Quinoclamine
CAS:Quinoclamine is a naphthoquinone derivative and is an NF-κB inhibitor.Formula:C10H6ClNO2Purity:99.13% - 99.28%Color and Shape:Orange PowderMolecular weight:207.617,4'-Dihydroxyflavone
CAS:7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.Formula:C15H10O4Purity:99.39% - 99.6%Color and Shape:SolidMolecular weight:254.24Emlenoflast sodium
CAS:Emlenoflast sodium (MCC7840 sodium), a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome,Formula:C19H24N4NaO3SColor and Shape:SolidMolecular weight:411.47SjDX5-271
CAS:SjDX5-271 is a 3 kDa peptide that inhibits the TLR4/MyD88/NF-κB signaling pathway. It induces cell polarization, alleviates liver inflammation, and protects mice from liver ischemia-reperfusion injury.Formula:C137H215N47O49SColor and Shape:SolidMolecular weight:3336.52NF-κΒ activator 2
CAS:NF-κΒ Activator 2 is a potent, orally active compound that efficiently activates NF-κB with an EC50 value of 1.58 μM.Formula:C16H11FN2O3Purity:99.32%Color and Shape:SolidMolecular weight:298.27Ref: TM-T39924
1mg94.00€2mg136.00€5mg226.00€10mg335.00€25mg538.00€50mg730.00€100mg938.00€1mL*10mM (DMSO)249.00€HS-1371
CAS:HS-1371 is a novel kinase inhibitor of receptor-interacting protein kinase 3 (RIP3) with an IC50 of 20.8 nM.Formula:C24H24N4OPurity:98%Color and Shape:SolidMolecular weight:384.47Sulforaphene
CAS:Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.Formula:C6H9NOS2Purity:98.01% - 99.19%Color and Shape:Slightly Yellowish LiquidMolecular weight:175.27Ref: TM-TL0016
1mg37.00€2mg52.00€5mg79.00€10mg119.00€25mg227.00€50mg338.00€100mg500.00€1mL*10mM (DMSO)69.00€Ac2-26 acetate
Ac2-26 acetate is an active N-terminal peptide of annexin A1(AnxA1).Formula:C141H210N32O44SPurity:98%Color and Shape:SolidMolecular weight:3089.43CORM-3
CAS:CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.Formula:C5H4ClNO5RuPurity:98%Color and Shape:SolidMolecular weight:294.61NF-κB-IN-1
CAS:NF-κB-IN-1 (1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-) is a potent NF-κB signaling pathwayFormula:C31H30O8Purity:99.03%Color and Shape:SolidMolecular weight:530.57Ref: TM-T9105
1mg166.00€5mg341.00€10mg550.00€25mg898.00€50mg1,216.00€100mg1,644.00€1mL*10mM (DMSO)398.00€Indacaterol
CAS:Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.Formula:C24H28N2O3Purity:100.00% - 99.63%Color and Shape:SolidMolecular weight:392.49Sulfuretin
CAS:Sulfuretin protects HepG2 cells from oxidative damage by scavenging ROS and activating HO-1 via Nrf2/ARE and JNK/ERK pathways.Formula:C15H10O5Purity:100% - 98.91%Color and Shape:SolidMolecular weight:270.24WITHAFERIN A
CAS:WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/Formula:C28H38O6Purity:97.41% - 99.83%Color and Shape:SolidMolecular weight:470.6Ref: TM-T5687
1mg85.00€5mg265.00€10mg393.00€25mg653.00€50mg929.00€100mg1,254.00€500mg2,517.00€1mL*10mM (DMSO)304.00€IRAK4-IN-28
CAS:IRAK4-IN-28 (compound 42), an orally-active IRAK4 inhibitor (IC50=8.9 nM), exhibits strong binding affinity with a Kd of 0.58 nM for the target enzyme.Formula:C27H31N9O3Purity:98%Color and Shape:SolidMolecular weight:529.59Isonardosinone
CAS:Isonardosinone, a nardosinone-type sesquiterpene from Nardostachys jatamansi, exhibits anti-neuroinflammatory and cytotoxic activities.Formula:C15H22O3Purity:98%Color and Shape:SolidMolecular weight:250.33GSK8612
CAS:GSK8612 is a highly selective and potent inhibitor of Tank-binding Kinase-1 (TBK1, pIC50: 6.8) .Formula:C17H17BrF3N7O2SPurity:99.46% - ≥98%Color and Shape:SolidMolecular weight:520.33Ref: TM-T5540
1mg47.00€2mg59.00€5mg92.00€10mg131.00€25mg215.00€50mg378.00€100mg567.00€1mL*10mM (DMSO)96.00€Ginsenoside Rg2
CAS:Ginsenoside Rg2 (Chikusetsusaponin I) is one of the major active components of ginseng, act as an NF-κB inhibitor.Formula:C42H72O13Purity:99.5% - 99.77%Color and Shape:SolidMolecular weight:785.01Ref: TM-T2873
2mg37.00€5mg52.00€10mg88.00€25mg131.00€50mg188.00€100mg279.00€500mg658.00€1mL*10mM (DMSO)87.00€Pratensein
CAS:Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.Formula:C16H12O6Purity:99.72%Color and Shape:SolidMolecular weight:300.26γ-Tocotrienol
CAS:γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E.Formula:C28H42O2Purity:97.27% - 98.13%Color and Shape:SolidMolecular weight:410.63Ref: TM-T19768
1mg47.00€2mg62.00€5mg92.00€10mg144.00€25mg235.00€50mg350.00€100mg515.00€200mg743.00€1mL*10mM (DMSO)97.00€
