NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Products of "NF-κB"
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Tyrosol
CAS:Tyrosol (2-(4-Hydroxyphenyl)ethanol) is a phenolic antioxidant that is naturally present in several foods such as wines and green tea and is present mostFormula:C8H10O2Purity:100% - 99.28%Color and Shape:SolidMolecular weight:138.16Astaxanthin
CAS:Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.Formula:C40H52O4Purity:95.1% - 99.79%Color and Shape:Needles From Acetone/Light Petroleum SolidMolecular weight:596.84TRAF-STOP inhibitor 6877002
CAS:TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.Formula:C17H17NOPurity:99.65%Color and Shape:SolidMolecular weight:251.32Handelin
CAS:Handelin has anti-inflammatory activity by inhibiting NF-κB activation and pro-inflammatory cytokine productions.Formula:C32H40O8Purity:99.02%Color and Shape:SolidMolecular weight:552.66RIPK2-IN-3
CAS:RIPK2-IN-3 (FCG806791773) is a RIPK2 inhibitor with anti-inflammatory and anticancer activities, useful for research on immune diseases and cancer.Formula:C25H22N4O2Purity:99.57%Color and Shape:SolidMolecular weight:410.47GSK2983559 free acid
CAS:GSK2983559 free acid selectively inhibits RIP2, reducing inflammatory cytokines in human bowel disease.Formula:C21H23N4O7PS2Purity:97.87% - 98.61%Color and Shape:SolidMolecular weight:538.53Narasin (sodium salt)
CAS:Narasin (sodium salt) (HainanMycin) induces tumor necrosis factor-related apoptosis-induced ligand (TRAIL)-mediated apoptosis by ER stress in glioma cells andFormula:C43H71NaO11Purity:98%Color and Shape:SolidMolecular weight:787.01Oditrasertib
CAS:Oditrasertib, a RIPK1 inhibitor characterized by an IC50 value below 100 nM, is employed in inflammation research.Formula:C14H15F2N3O2Purity:98.65% - 99.65%Color and Shape:SolidMolecular weight:295.28Naringin dihydrochalcone
CAS:Naringin dihydrochalcone (Naringin DC) is an inhibitor of CYP enzymes, used as an artificial sweetener.Formula:C27H34O14Purity:99.07% - 99.16%Color and Shape:Solid PowderMolecular weight:582.55Isodeoxyelephantopin
CAS:Isodeoxyelephantopin can inhibit the growth of various tumor cells.Formula:C19H20O6Purity:99.88%Color and Shape:SolidMolecular weight:344.36NIK SMI1
CAS:NIK SMI1 is an effective and selective NF-κB inducing kinase (NIK) inhibitor. It also inhibits NIK-catalyzed hydrolysis of ATP to ADP (IC50: 0.23±0.17 nM).Formula:C20H19N3O4Purity:99.04% - 99.99%Color and Shape:SolidMolecular weight:365.38Ref: TM-T16290
1mg87.00€5mg183.00€10mg296.00€25mg593.00€50mg932.00€100mg1,501.00€200mg2,052.00€1mL*10mM (DMSO)432.00€NDMC101
CAS:NDMC101 suppresses dipeptidyl peptidase-IV, NFATc1, and NF-κB in human T cells, modulating immunity.Formula:C13H9ClFNO2Purity:99.89%Color and Shape:SolidMolecular weight:265.67MRT67307
CAS:Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy.Formula:C26H36N6O2Purity:99.25% - 99.79%Color and Shape:SolidMolecular weight:464.6GSK481
CAS:GSK481 (GSK'481) is a RIP1(Receptor Interacting Protein Kinase1) inhibitor. Inhibition of RIP1 has been shown to hinder cell necrotic death.Formula:C21H19N3O4Purity:98.97%Color and Shape:SolidMolecular weight:377.39COX-2-IN-48
COX-2-IN-48 (5-25) serves as an inhibitor of COX-2, exhibiting an IC50 of 51.7 nM against human COX-2. It displays anti-inflammatory and analgesic effects in various rodent models through inhibition of the NF-κB pathway. COX-2-IN-48 (5-25) inhibits the degradation of IκB, phosphorylation and nuclear translocation of NF-κB p65, and the expression of COX-2 and iNOS.Color and Shape:Odour SolidCOX-2-IN-32
CAS:COX-2-IN-32 (Compound 2f) is a dual inhibitor of iNOS and COX-2, known to downregulate NF-κB expression.Formula:C25H24O6Purity:98%Color and Shape:SolidMolecular weight:420.45Methylthiouracil
CAS:Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.Formula:C5H6N2OSPurity:100% - 99.89%Color and Shape:Crystals Saturated Aqueous Solution Is Neutral Or Slightly Acidic (Ntp 1992)Molecular weight:142.18α-Lipoic Acid
CAS:α-Lipoic Acid, a sulfur-containing octanoic acid derivative, is biosynthesized from linoleic acid and used in dietary supplements.Formula:C8H14O2S2Purity:98.39% - 99.73%Color and Shape:Forms Yellowish Flakes Light Yellow To Yellow PowderMolecular weight:206.33Shikonin
CAS:Shikonin: TMEM16A inhibitor (IC50: 6.5μM), targets PKM2, suppresses NF-κB, inhibits TNF-α, and reduces exosome secretion.Formula:C16H16O5Purity:98.13% - 99.9%Color and Shape:SolidMolecular weight:288.3Ref: TM-T1125
5mg34.00€10mg52.00€25mg87.00€50mg140.00€100mg215.00€200mg319.00€500mg533.00€1mL*10mM (DMSO)52.00€20(S)-Ginsenoside Rg3
CAS:20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.Formula:C42H72O13Purity:100% - 99.93%Color and Shape:SolidMolecular weight:785.01
