NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Products of "NF-κB"
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UBS109
CAS:UBS109, a curcumin analog, is a DNA demethylating agent in pancreatic cancer that promotes osteoblast differentiation and mineralization.Formula:C18H17N3OPurity:99.48%Color and Shape:SolidMolecular weight:291.35Ref: TM-T88314
2mg38.00€5mg57.00€10mg92.00€25mg166.00€50mg254.00€100mg389.00€200mg566.00€1mL*10mM (DMSO)63.00€ISOGINKGETIN
CAS:ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.Formula:C32H22O10Purity:98% - 99.72%Color and Shape:SolidMolecular weight:566.51Denosumab
CAS:Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligandFormula:C6404H9912N1724O2004S50Purity:98.4% (SEC-HPLC) - 99.90%Color and Shape:LiquidMolecular weight:144.71 kDaTrovafloxacin mesylate
CAS:Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).Formula:C21H19F3N4O6SPurity:99.12%Color and Shape:SolidMolecular weight:512.46Selinidin
CAS:Selinidin decreases phosphorylation of phospholipase C-gamma1, p38 mitogen-activated protein kinase, and IkappaB-alpha upon FcepsilonRI stimulation.Formula:C19H20O5Purity:98%Color and Shape:SolidMolecular weight:328.364Biricodar dicitrate
CAS:Biricodar dicitrate (VX-710) is a potent MDR inhibitor with no anticancer activity and can be used to study prostate cancer.Formula:C46H57N3O21Purity:98.67% - 99.34%Color and Shape:SolidMolecular weight:987.95Ginsenoside Rg6
CAS:Ginsenoside Rg6 inhibits the proliferation and induces apoptosis of human lymphoma JK cellsFormula:C42H70O12Purity:≥98%Color and Shape:SolidMolecular weight:767Obtusifolin
CAS:Obtusifolin is an antioxidant that combats diabetes, bone-resorption, diabetic retinopathy, pain, and cognitive decline.Formula:C16H12O5Purity:100% - 99.79%Color and Shape:SolidMolecular weight:284.26Ref: TM-T4S0969
1mg70.00€5mg187.00€10mg279.00€25mg472.00€50mg658.00€100mg933.00€1mL*10mM (DMSO)187.00€Molsidomine
CAS:Molsidomine, an oral vasodilator, turns into linsidomine in the liver, releasing NO for prolonged effects.Formula:C9H14N4O4Purity:100% - 99.98%Color and Shape:Colorless Or White Crystalline PowderMolecular weight:242.23Articaine hydrochloride
CAS:Articaine hydrochloride (Hoe-045) is a thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.Formula:C13H21ClN2O3SPurity:99.76%Color and Shape:White Crystalline PowderMolecular weight:320.846‴-Feruloylspinosin
CAS:6‴-Feruloylspinosin (6'''-Feruloylspinosin) may possess anti-inflammatory activity.Formula:C38H40O18Purity:98.69% - 99.91%Color and Shape:SolidMolecular weight:784.71Praeruptorin A
CAS:Praeruptorin A ((+)-Praeruptorin A) has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulinFormula:C21H22O7Purity:99.63% - 99.65%Color and Shape:SolidMolecular weight:386.4ADS032
CAS:ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity for the study of respiratory inflammation or infection.Formula:C22H29NO4SPurity:99.33%Color and Shape:SolidMolecular weight:403.54MCC950
CAS:CP-456773 (MCC950) inhibits NLRP3 inflammasome, prevents IL-1β secretion, and reduces multiple sclerosis model severity.Formula:C20H24N2O5SPurity:97%Color and Shape:SolidMolecular weight:404.48Rhoifolin
CAS:Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.Formula:C27H30O14Purity:98.11% - 98.87%Color and Shape:SolidMolecular weight:578.52Necroptosis-IN-1
CAS:Necroptosis-IN-1 is a potent necroptosis inhibitor of RIPK1. It is an analog of Necrostatin-1.Formula:C12H10ClN3O2Purity:99.60% - 99.73%Color and Shape:SolidMolecular weight:263.68Ref: TM-T9305
1mg64.00€5mg117.00€10mg187.00€25mg319.00€50mg449.00€100mg638.00€200mg840.00€1mL*10mM (DMSO)149.00€Neochlorogenic acid
CAS:Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.Formula:C16H18O9Purity:99.12% - 99.73%Color and Shape:White PowderMolecular weight:354.31ACHP Hydrochloride
CAS:ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an IC50 of 8.5 nM.Formula:C21H25ClN4O2Purity:100%Color and Shape:SolidMolecular weight:400.9Ref: TM-T10237
1mg66.00€5mg144.00€10mg227.00€25mg375.00€50mg540.00€100mg777.00€500mg1,549.00€1mL*10mM (DMSO)159.00€IRAK inhibitor 6
CAS:IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4, IC50: 160 nM).Formula:C20H20N4O3SPurity:99.44%Color and Shape:SolidMolecular weight:396.46NT-0249
CAS:NT-0249 is an inflammatory vesicle NLRP3 inhibitor with anti-inflammatory activity that reverses high-fat diet-induced obesity.Formula:C22H28N5NaO4SColor and Shape:SoildMolecular weight:481.54
