CXCR
CXCRs are a subset of GPCRs that bind to chemokines, small signaling proteins that guide the movement of immune cells towards sites of inflammation, infection, or injury. CXCRs play crucial roles in immune responses, cancer metastasis, and inflammatory diseases. Modulators of CXCRs are being investigated for their potential in treating autoimmune diseases, cancer, and chronic inflammatory conditions. At CymitQuimica, we offer a range of high-quality CXCR modulators to support your research in immunology, oncology, and inflammation.
Products of "CXCR"
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AZD-5069
CAS:AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).Formula:C18H22F2N4O5S2Purity:98.38% - 98.63%Color and Shape:SolidMolecular weight:476.52Ref: TM-T7681
1mg50.00€2mg65.00€5mg85.00€10mg124.00€25mg227.00€50mg350.00€100mg522.00€500mg1,130.00€1mL*10mM (DMSO)88.00€AZD8797
CAS:AZD8797 (KAND567) is a CX3CR1 antagonist with potential protective effects against neuronal damage and prevents nociceptive hypersensitivity in rats.Formula:C19H25N5OS2Purity:98.73% - 99.68%Color and Shape:SolidMolecular weight:403.56Ref: TM-T14384
1mg90.00€5mg188.00€10mg354.00€25mg748.00€50mg938.00€100mg1,359.00€1mL*10mM (DMSO)216.00€ML339
CAS:ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.Formula:C26H32ClN3O5Purity:99.46%Color and Shape:SolidMolecular weight:502SCH 546738
CAS:SCH 546738 is an orally available, selective and potent CXCR3 antagonist that attenuates the development of autoimmune diseases and delays graft rejection.Formula:C23H31Cl2N7OPurity:98.67%Color and Shape:SolidMolecular weight:492.45Danirixin
CAS:Danirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).Formula:C19H21ClFN3O4SPurity:100.00% - 99.78%Color and Shape:SolidMolecular weight:441.9SRT3109
CAS:SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.Formula:C18H23F2N5O4S2Purity:99.65% - 99.92%Color and Shape:SolidMolecular weight:475.53USL311
CAS:USL311 blocks CXCR4/SDF-1 interaction, inhibits tumor cell growth and migration.Formula:C24H34N6OPurity:98.46% - 99.56%Color and Shape:SolidMolecular weight:422.57Ref: TM-T17208
1mg42.00€5mg88.00€10mg127.00€25mg250.00€50mg393.00€100mg628.00€500mg1,304.00€1mL*10mM (DMSO)87.00€UNBS5162
CAS:UNBS5162 (UNBS-5162) is a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers.Formula:C17H18N4O3Purity:98.37% - 99.97%Color and Shape:SolidMolecular weight:326.35Ref: TM-T2477
1mg39.00€5mg81.00€10mg116.00€25mg215.00€50mg340.00€100mg540.00€200mg787.00€1mL*10mM (DMSO)89.00€ATI-2341
CAS:ATI-2341, pepducin targeting the CXCR4, is an allosteric agonist activating the Gi to promote inhibition of cAMP production and induce calcium mobilization.Formula:C104H178N26O25S2Color and Shape:SolidMolecular weight:2256.82Nicotinamide N-oxide
CAS:Nicotinamide N-oxide, a metabolite of nicotinamide and precursor to NAD+, is reduced by liver enzyme xanthine oxidase.Formula:C6H6N2O2Purity:99.61% - 99.9%Color and Shape:SolidMolecular weight:138.12WZ811
CAS:WZ811 is a novel and effective small molecular CXCR4 antagonist (EC50: 0.3 nM).Formula:C18H18N4Purity:99.42% - ≥95%Color and Shape:SolidMolecular weight:290.36Plerixafor octahydrochloride
CAS:Plerixafor octahydrochloride mobilizes HSCs by blocking SDF-1alpha/CXCR4 interaction, facilitating their release into circulation.Formula:C28H62Cl8N8Purity:98.01% - 99.79%Color and Shape:SolidMolecular weight:794.46AMD-070 hydrochloride
CAS:AMD-070 hydrochloride is a CXCR4 antagonist, is useful for Anti HIV.Formula:C21H28ClN5Purity:98.38% - 98.57%Color and Shape:SolidMolecular weight:385.93(R)-SCH 546738
CAS:(R)-SCH 546738, the R-isomer of SCH 546738, is a non-competitive, orally active antagonist targeting the CXCR3 receptor, exhibiting a K_i of 0.4 nM for the human CXCR3 receptor.Formula:C23H31Cl2N7OColor and Shape:SolidMolecular weight:492.45CCX662
CAS:CCX662 is a CXCR7 antagonist. It inhibits the binding of 125I-CXCL12 to CXCR7 with an IC50 of 9 nM. This compound is suitable for use in cancer research.Formula:C28H37N5O4SColor and Shape:SolidMolecular weight:539.69JMS-17-2
CAS:JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).Formula:C25H26ClN3OPurity:98.70% - 99.44%Color and Shape:SolidMolecular weight:419.95Ref: TM-T5849
1mg40.00€2mg52.00€5mg87.00€10mg131.00€25mg221.00€50mg344.00€100mg512.00€1mL*10mM (DMSO)96.00€Mavorixafor
CAS:Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding.Formula:C21H27N5Purity:98.56%Color and Shape:SolidMolecular weight:349.47Ref: TM-TQ0174
1mg70.00€2mg92.00€5mg153.00€10mg220.00€25mg396.00€50mg588.00€100mg835.00€1mL*10mM (DMSO)249.00€Burixafor hydrobromide
CAS:Burixafor hydrobromide is an oral CXCR4 blocker with anti-angiogenic properties, potentially treating choroid neovascularization.Formula:C27H52BrN8O3PPurity:98%Color and Shape:SolidMolecular weight:647.644MSX-130
CAS:MSX-130 is CXCR4 Antagonist.Formula:C36H26N4Purity:99.19%Color and Shape:SolidMolecular weight:514.62Delmetacin
CAS:Delmetacin: a non-steroidal anti-inflammatory drug with analgesic properties, inhibits CXCR1.Formula:C18H15NO3Purity:99.42%Color and Shape:SolidMolecular weight:293.32
