STAT
STAT proteins are critical components of the JAK/STAT signaling pathway, which transmits extracellular signals from cytokines and growth factors to the cell nucleus, influencing gene expression. STAT proteins are involved in regulating immune responses, cell growth, differentiation, and survival. Dysregulation of STAT signaling is implicated in various diseases, including cancer, autoimmune disorders, and chronic inflammation. At CymitQuimica, we provide a comprehensive range of STAT pathway modulators to support your research in signal transduction, immunology, and therapeutic development.
Products of "STAT"
Sort by
Stafib-2
CAS:Stafib-2 is a potent and selective inhibitor of the transcription factor STAT5b.Stafib-2 inhibits STAT5b and STAT5a with IC50 values of 82 nM and 1.7 μM,Formula:C28H26N2O12P2Purity:98.97%Color and Shape:SolidMolecular weight:644.46Ref: TM-T9646
1mg208.00€5mg518.00€10mg740.00€25mg1,093.00€50mg1,473.00€100mg2,015.00€1mL*10mM (DMSO)737.00€AS2863619
CAS:AS2863619 is an oral inhibitor of cyclin-dependent kinase(CDK8) and CDK19. Inhibition of CDK8/19 enhances STAT5 activation.Cost-effective and quality-assured.Formula:C16H14Cl2N8OPurity:100%Color and Shape:SolidMolecular weight:405.24Ref: TM-T8378
1mg131.00€2mg180.00€5mg274.00€10mg432.00€25mg715.00€50mg1,008.00€100mg1,359.00€1mL*10mM (DMSO)303.00€RO8191
CAS:RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.Formula:C14H5F6N5OPurity:98.85% - ≥98%Color and Shape:SolidMolecular weight:373.21Atractylenolide I
CAS:Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.Formula:C15H18O2Purity:97.55% - 99.83%Color and Shape:SolidMolecular weight:230.3KT-333
CAS:KT-333 is a potent, highly selective, heterobifunctional degrader of STAT3 for the treatment of a variety of STAT3-dependent pathologies, antitumor.Formula:C60H74ClN10O14PSPurity:98.12%Color and Shape:SolidMolecular weight:1257.78Tetramethylcurcumin
CAS:Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it alsoFormula:C25H28O6Purity:99.94% - ≥98%Color and Shape:SolidMolecular weight:424.49PMMB-187
CAS:PMMB-187, a selective STAT3 inhibitor, exhibits an IC50 of 1.81 μM in MDA-MB-231 cells. This compound induces apoptosis in MDA-MB-231 cells by inhibiting STAT3 transcriptional activity and nuclear translocation, reducing mitochondrial membrane potential, increasing reactive oxygen species (ROS) production, and upregulating the expression of apoptosis-related proteins. PMMB-187 is useful for research in the field of cancer.Formula:C27H23BrN2O6S2Color and Shape:SolidMolecular weight:615.52Stafia-1
CAS:Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.Formula:C24H27O10PPurity:98.08%Color and Shape:SolidMolecular weight:506.44Ref: TM-T9339
1mg86.00€5mg187.00€10mg309.00€25mg525.00€50mg757.00€100mg1,035.00€500mg2,110.00€1mL*10mM (DMSO)217.00€Protosappanin A
CAS:Protosappanin A combats brain inflammation, suppresses rat heart transplant rejection, fights MRSA, and inhibits HIV with a 12.6 uM IC50.Formula:C15H12O5Purity:100% - 99.42%Color and Shape:SolidMolecular weight:272.25Ref: TM-TJS1779
1mg87.00€5mg216.00€10mg354.00€25mg582.00€50mg825.00€100mg1,111.00€1mL*10mM (DMSO)197.00€UC-514321
CAS:UC-514321 directly targets STAT3/5 and represses TET1 expression.Formula:C26H35NO5Purity:97%Color and Shape:SolidMolecular weight:441.56Ref: TM-T13950
1mg78.00€5mg169.00€10mg264.00€25mg528.00€50mg810.00€100mg1,169.00€200mg1,568.00€1mL*10mM (DMSO)178.00€Morusin
CAS:Morusin shows anti-tumor, antioxidant, and anti-inflammatory properties by inhibiting STAT3, NFκB, and inducing apoptosis.Formula:C25H24O6Purity:98.68% - 99.8%Color and Shape:SolidMolecular weight:420.45Antitumor agent-73
CAS:Antitumor Agent-73, derived from Diosgenin, blocks STAT3 and activates Pdia3, showing strong cancer cell line efficacy.Formula:C50H82BrO4PPurity:98%Color and Shape:SolidMolecular weight:858.06Picroside I
CAS:Picroside I (6'-Cinnamoylcatalpol), a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B.Formula:C24H28O11Purity:99.70%Color and Shape:SolidMolecular weight:492.47SC-43
CAS:SC-43 is a potent and orally active agonist of SHP-1 (PTPN6).Formula:C21H13ClF3N3O2Purity:98.44%Color and Shape:SolidMolecular weight:431.8S3I-201
CAS:S3I-201 (S3I-201) is a selective Stat3 inhibitor (IC50: 86±33 μM) and low effect towards STAT1/5.Formula:C16H15NO7SPurity:97.83%Color and Shape:SolidMolecular weight:365.36BD750
CAS:BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM inFormula:C14H13N3OSPurity:99.02%Color and Shape:SolidMolecular weight:271.34Stattic
CAS:Stattic (STAT3 Inhibitor V) is a STAT3 inhibitor (IC50=5.1 μM) that selectively inhibits STAT3 activation, dimerization, and nuclear translocation.Formula:C8H5NO4SPurity:98.54% - 99.76%Color and Shape:SolidMolecular weight:211.19Ref: TM-T6308
5mg35.00€10mg51.00€25mg85.00€50mg124.00€100mg187.00€200mg279.00€500mg465.00€1mL*10mM (DMSO)55.00€WP1066
CAS:WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.Formula:C17H14BrN3OPurity:98.92% - 99.73%Color and Shape:SolidMolecular weight:356.22SC99
CAS:SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.Formula:C15H8Cl2FN3OPurity:99.56%Color and Shape:SolidMolecular weight:336.15Ref: TM-T8719
1mg46.00€5mg93.00€10mg140.00€25mg240.00€50mg363.00€100mg452.00€200mg630.00€1mL*10mM (DMSO)99.00€AS1517499
CAS:AS1517499 is a potent STAT6 inhibitor with IC50 of 21 nMFormula:C20H20ClN5O2Purity:98.27% - 98.7%Color and Shape:SolidMolecular weight:397.86Ref: TM-T4476
1mg40.00€2mg52.00€5mg88.00€10mg119.00€25mg235.00€50mg376.00€100mg469.00€500mg1,064.00€1mL*10mM (DMSO)87.00€
