STAT
STAT proteins are critical components of the JAK/STAT signaling pathway, which transmits extracellular signals from cytokines and growth factors to the cell nucleus, influencing gene expression. STAT proteins are involved in regulating immune responses, cell growth, differentiation, and survival. Dysregulation of STAT signaling is implicated in various diseases, including cancer, autoimmune disorders, and chronic inflammation. At CymitQuimica, we provide a comprehensive range of STAT pathway modulators to support your research in signal transduction, immunology, and therapeutic development.
Products of "STAT"
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inS3-54A18
CAS:inS3-54A18 is an effective inhibitor of STAT3. inS3-54A18 has anticancer effects.Formula:C23H16ClNO2Purity:99.54%Color and Shape:SolidMolecular weight:373.83Ref: TM-T15582
2mg42.00€5mg65.00€10mg93.00€25mg160.00€50mg226.00€100mg320.00€200mg452.00€1mL*10mM (DMSO)71.00€SH5-07
CAS:SH5-07 is a hydroxamic acid-based Stat3 inhibitor (IC50: 3.9 μM).Formula:C29H28F5N3O5SPurity:95.54%Color and Shape:SolidMolecular weight:625.61Ref: TM-TQ0052
1mg37.00€5mg80.00€10mg117.00€25mg197.00€50mg294.00€100mg425.00€200mg602.00€1mL*10mM (DMSO)99.00€STAT3-IN-34
STAT3-IN-34 (Compound 15E) acts as a STAT3 inhibitor, blocking both the nuclear translocation and the transcriptional regulator activity of STAT3. It effectively inhibits HaCaT cell proliferation with an IC50 value of 0.008 μM. Additionally, STAT3-IN-34 reduces IL-17A expression and mitigates Imiquimod-induced psoriasis in mouse models.Formula:C19H16N2O4SColor and Shape:SolidMolecular weight:368.41BP-1-102
CAS:BP-1-102 is an orally active, effective and specific STAT3 inhibitor.Formula:C29H27F5N2O6SPurity:99.25% - 99.81%Color and Shape:SolidMolecular weight:626.59Ref: TM-T3708
1mg39.00€2mg51.00€5mg84.00€10mg119.00€25mg210.00€50mg354.00€100mg522.00€1mL*10mM (DMSO)104.00€Colivelin
CAS:Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).Formula:C119H206N32O35Purity:96.56%Color and Shape:SolidMolecular weight:2645.1Panaxadiol
CAS:Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.Formula:C30H52O3Purity:98% - 99.9%Color and Shape:SolidMolecular weight:460.73WZ-2-033
CAS:WZ-2-033 is a potent STAT3 inhibitor. It inhibits proliferation, colony survival, migration, and invasion of MDA-MB-231, HCC70, and MDA-MB231-4175 cells, with IC50 values of 0.7, 1.3, and 1.3 μM respectively.Formula:C25H18F3N3O4SColor and Shape:SolidMolecular weight:513.49NT219
CAS:NT219 is a dual inhibitor of insulin receptor substrate 1/2 (IRS1/2) and STAT3 that enhances the aggregation of misfolded prion proteins NT219 Effects.Formula:C16H14BrNO5SPurity:98.06% - 99.72%Color and Shape:SolidMolecular weight:412.26MNK8
CAS:MNK8 is a potent STAT3 inhibitor, impairs DNA binding, and inhibits liver cancer cell growth.Formula:C15H12N2O2Purity:99.74%Color and Shape:SolidMolecular weight:252.27Nifuroxazide
CAS:Nifuroxazide (Diarlidan), an oral nitrofuran antidiarrheal, blocks STAT1/3/5 activation.Formula:C12H9N3O5Purity:98.31% - 99.87%Color and Shape:Yellow SolidMolecular weight:275.22STAT3-IN-20
CAS:STAT3-IN-20 (Compound 40), with an IC50 of 0.65 μM, is a selective inhibitor targeting the SH2 domain of STAT3, thereby impeding its phosphorylation, nuclearFormula:C30H27F4N7SPurity:98%Color and Shape:SolidMolecular weight:593.64Scutellarin
CAS:Scutellarin from Scutellaria inhibits RANKL in osteoclasts and STAT3/Girdin/Akt in HCC cells.Formula:C21H18O12Purity:95.86% - 99.32%Color and Shape:SolidMolecular weight:462.36AS1810722
CAS:AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM.Formula:C25H25F2N7OPurity:99.13%Color and Shape:SolidMolecular weight:477.51Triacetylresveratrol
CAS:Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.Formula:C20H18O6Purity:99.81%Color and Shape:Off White PowderMolecular weight:354.35STAT3 degrader-2
CAS:STAT3 Degrader-2 is a PROTAC-based compound that effectively reduces the total STAT3 protein levels, and is utilized in the research of cancer and variousFormula:C59H62N9O13PPurity:98%Color and Shape:SolidMolecular weight:1136.15Arnicolide D
CAS:Arnicolide D is a sesquiterpene lactone.Formula:C19H24O5Purity:96.66%Color and Shape:SolidMolecular weight:332.39Niclosamide
CAS:Niclosamide (Niclocide)(BAY2353) is used to treat most tapeworm infections by inhibiting DNA replication.Formula:C13H8Cl2N2O4Purity:96.83% - 98.9%Color and Shape:Pale Yellow Crystals SolidMolecular weight:327.12(R)-Lisofylline
CAS:(R)-Lisofylline ((R)-Lisophylline) is an inhibitor of lysophosphatidic acid acyltransferase (IC50 = 0.6 µM).Formula:C13H20N4O3Purity:99.50%Color and Shape:SolidMolecular weight:280.32C188-9
CAS:C188-9 (TTI-101) is a Stat3 inhibitor with an IC50 of 4-7 μM.Formula:C27H21NO5SPurity:100% - 99.19%Color and Shape:SolidMolecular weight:471.52Ref: TM-T4650
1mg46.00€2mg59.00€5mg87.00€10mg123.00€25mg250.00€50mg398.00€100mg593.00€500mg1,264.00€1mL*10mM (DMSO)96.00€STAT3-IN-B9
CAS:STAT3-IN-B9 (B9) is an inhibitor of abnormal STAT3 activation and inhibits the proliferation of tumor cells including MDA-MB-468, MDA-MB-231, and DU145.Formula:C20H13NO5SPurity:98.16%Color and Shape:SolidMolecular weight:379.39Ref: TM-T28865
1mg115.00€2mg162.00€5mg249.00€10mg369.00€25mg562.00€50mg787.00€100mg1,054.00€200mg1,406.00€1mL*10mM (DMSO)269.00€
