cAMP
cAMP is a second messenger important in many biological processes, including the regulation of metabolism, gene expression, and cell growth. In the MAPK signaling pathway, cAMP can modulate the activity of various kinases, including PKA, which in turn influences the MAPK cascade. Dysregulation of cAMP signaling is implicated in various diseases, including cancer and cardiovascular disorders. At CymitQuimica, we offer a variety of cAMP modulators to support your research in signal transduction, metabolism, and disease pathology.
Products of "cAMP"
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Torbafylline
CAS:Torbafylline is a xanthine-based PDE inhibitor reducing protein breakdown via PDE4/cAMP/EPAC/PI3K/Akt in rats with burns, cancer, or sepsis.Formula:C16H26N4O4Purity:98% - 99%Color and Shape:SoildMolecular weight:338.4Ref: TM-T67965
1mg128.00€5mg304.00€10mg457.00€25mg747.00€50mg1,026.00€100mg1,406.00€500mg2,812.00€1mL*10mM (DMSO)314.00€BC 11-38
CAS:BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).Formula:C15H16N2OS2Purity:97.71% - 98.72%Color and Shape:SolidMolecular weight:304.43Ref: TM-T21865
1mg35.00€5mg70.00€10mg97.00€25mg202.00€50mg329.00€100mg527.00€200mg747.00€1mL*10mM (DMSO)81.00€I942
CAS:I942 is a novel, selective ACyclic nucleotide (NCN) EPAC1 agonist that activates exchange proteins to regulate inflammatory gene expression in human umbilicalFormula:C20H19NO4SPurity:99.75%Color and Shape:SolidMolecular weight:369.43Catalpalactone
CAS:Catalpalactone: antitermitic, cytotoxic, inhibits NO in cells (IC50 9.80µM), reduces dopamine synthesis, hinders TPA-induced EBV-EA activation.Formula:C15H14O4Purity:98%Color and Shape:SolidMolecular weight:258.27RS-25344 hydrochloride
CAS:RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitorFormula:C19H14ClN5O4Purity:99.25%Color and Shape:SolidMolecular weight:411.8Ref: TM-T23256
2mg34.00€5mg52.00€10mg85.00€25mg170.00€50mg259.00€100mg374.00€200mg545.00€1mL*10mM (DMSO)65.00€Rp-cAMPS sodium
CAS:Rp-cAMPS sodium is a phosphorothioate analog of cAMP, a PKA inhibitor and cAMP antagonist that inhibits cAMP-dependent protein kinases.Formula:C10H11N5NaO5PSPurity:99.71%Color and Shape:SolidMolecular weight:367.250990CL
CAS:0990CL is an effective heterotrimer Gαi subunit specific inhibitor, which can interact with purified Go± in GDP-bound state, and can block α2AR mediated cAMPFormula:C21H21N5Purity:98.86%Color and Shape:SolidMolecular weight:343.42Ref: TM-T13983
1mg202.00€5mg512.00€10mg740.00€25mg1,121.00€50mg1,539.00€100mg2,072.00€1mL*10mM (DMSO)535.00€LGD-6972
CAS:LGD-6972 is an antagonist of glucagon receptor.Formula:C43H46N2O5SPurity:98.8% - 99.33%Color and Shape:SolidMolecular weight:702.9Ref: TM-T11845
1mg88.00€5mg187.00€10mg274.00€25mg472.00€50mg692.00€100mg938.00€1mL*10mM (DMSO)283.00€GAT211
CAS:GAT211 (AZ-4) is a cannabinoid 1 receptor (CB1R) positive allosteric modulator (PAM) for the study of epilepsy.Formula:C22H18N2O2Purity:99.7%Color and Shape:SolidMolecular weight:342.39Ref: TM-T27405
1mg35.00€5mg70.00€10mg96.00€25mg157.00€50mg221.00€100mg328.00€500mg792.00€1mL*10mM (DMSO)78.00€LY404039
CAS:LY404039 (pomaglumetad) is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).Formula:C7H9NO6SPurity:99% - 99.16%Color and Shape:SolidMolecular weight:235.22MRS-1706
CAS:MRS-1706: Ki of 1.39nM for A2B; selective inverse agonist; also affects A2A, A1, A3.Formula:C27H29N5O5Purity:97.95%Color and Shape:SolidMolecular weight:503.55Ref: TM-T16136
1mg37.00€2mg52.00€5mg79.00€10mg119.00€25mg240.00€50mg472.00€100mg687.00€1mL*10mM (DMSO)88.00€KI-7
CAS:KI-7 is an adenosine A2B receptor positive allosteric modulator.Formula:C23H18N2O2Purity:98.03%Color and Shape:SolidMolecular weight:354.4Ref: TM-T9238
2mg38.00€5mg58.00€10mg90.00€25mg182.00€50mg279.00€100mg420.00€200mg592.00€1mL*10mM (DMSO)65.00€CB1R Allosteric modulator 3
CAS:CB1R Allosteric modulator 3 is a CB1R modulator.CB1R Allosteric modulator 3 inhibits cAMP, and can be used for the study of obesity and nicotine addiction.Formula:C22H17ClN2O2Purity:98.18%Color and Shape:SolidMolecular weight:376.84Enoximone
CAS:Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure.Formula:C12H12N2O2SPurity:95.52%Color and Shape:SolidMolecular weight:248.3Forskolin
CAS:Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).Formula:C22H34O7Purity:98.83% - 99.86%Color and Shape:Less Crystalline Solid Colorless Crystalline SolidMolecular weight:410.5Ref: TM-T2939
5mg43.00€10mg56.00€25mg86.00€50mg96.00€100mg144.00€200mg182.00€500mg306.00€1mL*10mM (DMSO)56.00€Piclamilast
CAS:Piclamilast (RP 73401) is a PDE4 inhibitor.Formula:C18H18Cl2N2O3Purity:98.28%Color and Shape:SolidMolecular weight:381.25Fargesone B
CAS:Fargesone B inhibits the vascular smooth muscle contraction by suppressing the voltage- and receptor-activated calcium influxes in a nonselective manner.Formula:C21H24O6Purity:98%Color and Shape:SolidMolecular weight:372.417SAX-187
CAS:SAX-187 (SAX-187) has high-affinity binding at the human 5-HT6 receptor.Formula:C15H13ClN4O2S2Purity:97.82% - 98%Color and Shape:SolidMolecular weight:380.87Ref: TM-T3183
1mg84.00€5mg160.00€10mg259.00€25mg419.00€50mg562.00€100mg775.00€200mg1,026.00€1mL*10mM (DMSO)170.00€TDI-10229
CAS:TDI-10229: potent oral sAC inhibitor, IC50=195 nM. Good mouse pharmacokinetics for in vivo use.Formula:C16H16ClN5Purity:97.77%Color and Shape:SoildMolecular weight:313.78Ref: TM-T64355
1mg42.00€5mg165.00€10mg235.00€25mg432.00€50mg648.00€100mg938.00€200mg1,264.00€1mL*10mM (DMSO)177.00€TP-10
CAS:TP-10 is a selective inhibitor of PDE10A against other PDEs with IC50 of 0.8 nM.Formula:C26H19F3N4OPurity:98.48%Color and Shape:SolidMolecular weight:460.45Ref: TM-T13189
1mg92.00€2mg120.00€5mg187.00€10mg279.00€25mg487.00€50mg705.00€100mg998.00€500mg1,882.00€1mL*10mM (DMSO)188.00€
