MEK
MEK is a dual-specificity kinase that plays a central role in the MAPK/ERK signaling pathway by activating ERK through phosphorylation. MEK signaling is crucial for regulating cell growth, survival, and differentiation. Aberrant MEK activity has been implicated in various cancers and developmental disorders, making it an important therapeutic target. At CymitQuimica, we provide a variety of MEK inhibitors and modulators to support your research in oncology, cell signaling, and therapeutic development.
Products of "MEK"
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CI-1040
CAS:CI-1040 (PD 184352) (PD184352) is an ATP non-competitive MEK1/2 inhibitor (IC50: 17 nM).Formula:C17H14ClF2IN2O2Purity:99.64%Color and Shape:Off-White To Pale Beige SolidMolecular weight:478.66Cobimetinib
CAS:Cobimetinib (GDC-0973) is a MEK1 inhibitor with selective and oral activity. Cobimetinib exhibits antitumor activity. Cost-effective and quality-assured.Formula:C21H21F3IN3O2Purity:100% - 99.61%Color and Shape:SolidMolecular weight:531.31Ref: TM-T3623
1mg40.00€2mg51.00€5mg85.00€10mg96.00€25mg173.00€50mg276.00€100mg454.00€500mgTo inquire1mL*10mM (DMSO)88.00€Binimetinib
CAS:Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity. Cost-effective and quality-assured.Formula:C17H15BrF2N4O3Purity:100% - 99%Color and Shape:SolidMolecular weight:441.23Glycinexylidide
CAS:Glycinexylidide (GX), the active metabolite of the local anesthetic Lidocaine, exhibits properties significant in inhibiting sodium channels with complexFormula:C10H14N2OPurity:98%Color and Shape:SolidMolecular weight:178.23PD318088
CAS:PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binding simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-Formula:C16H13BrF3IN2O4Purity:99.81%Color and Shape:SolidMolecular weight:561.09Nedometinib
CAS:Nedometinib (NFX-179) is a MEK1 inhibitor with anticancer and antitumor activities, which can be used to study malignant tumors.Formula:C17H16FIN4O3Purity:99.18%Color and Shape:SolidMolecular weight:470.24Ref: TM-T78209
1mg74.00€5mg159.00€10mg226.00€25mg373.00€50mg593.00€100mg785.00€200mg1,035.00€1mL*10mM (DMSO)165.00€BAY-6035
CAS:BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). BAY-6035 has more than 100-fold selectivity over other histone methyltransferases.Formula:C22H28N4O3Purity:99.39%Color and Shape:SolidMolecular weight:396.48Midkine Protein, Human, Recombinant (His & Avi), Biotinylated
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed asColor and Shape:Lyophilized PowderMolecular weight:16.46 kDa (predicted) same as Tris-Bis PAGE result.AZD8330
CAS:AZD8330 (ARRY-704) is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1.Formula:C16H17FIN3O4Purity:98.72%Color and Shape:SolidMolecular weight:461.23MEK inhibitor
CAS:MEK inhibitor is a MEK receptor and cell cycle protein/CDK complex inhibitor with antitumor activity that can be used to study tumor cell proliferation.Formula:C26H26N4O2Purity:97.48%Color and Shape:SolidMolecular weight:426.51Lidocaine hydrochloride
CAS:Lidocaine HCl: local anesthetic, antiarrhythmic, stronger & longer-lasting than procaine but shorter than bupivacaine/prilocaine.Formula:C14H23ClN2OPurity:99.81% - 99.92%Color and Shape:White Crystal PowderMolecular weight:270.798zapnometinib
CAS:Zapnometinib (ATR-002) is a MEK inhibitor.Formula:C13H7ClF2INO2Purity:99.67%Color and Shape:SolidMolecular weight:409.55Midkine Protein, Mouse, Recombinant (His)
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed asColor and Shape:Lyophilized PowderMolecular weight:14.03 kDa (predicted). The protein migrates to 17-20 kDa based on Tris-Bis PAGE result.PD 198306
CAS:PD 198306: a MEK inhibitor with antihyperalgesic properties, reduces Streptozocin-boosted active ERK1.Formula:C18H16F3IN2O2Purity:99.75%Color and Shape:SolidMolecular weight:476.23Ref: TM-T21980
1mg64.00€5mg138.00€10mg188.00€25mg330.00€50mg472.00€100mg655.00€500mg1,293.00€1mL*10mM (DMSO)160.00€
