Ras
Ras proteins are small GTPases that act as molecular switches in the MAPK signaling pathway, controlling cell growth, differentiation, and survival. Activated Ras initiates a signaling cascade that includes Raf, MEK, and ERK, leading to various cellular responses. Mutations in Ras genes are common in cancers, making Ras an important focus of cancer research. At CymitQuimica, we offer a range of Ras modulators to support your research in cancer biology, signal transduction, and therapeutic development.
Products of "Ras"
Sort by
ARS-1323
CAS:ARS-1323 is the racemate of ARS-1620 and a mutant K-ras G12C inhibitor.Formula:C21H17ClF2N4O2Purity:98.88%Color and Shape:SolidMolecular weight:430.84FTI-277 hydrochloride
CAS:FTI-277 HCl: potent FTase inhibitor, IC50 500 pM, 100x more selective than GGTase I.Formula:C22H30ClN3O3S2Purity:97.57% - 97.61%Color and Shape:SolidMolecular weight:484.07Ref: TM-T2700
1mg52.00€2mg73.00€5mg96.00€10mg175.00€25mg320.00€50mg537.00€100mg753.00€1mL*10mM (DMSO)111.00€Kobe2602
CAS:Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities.Formula:C14H9F4N5O4SPurity:98.36% - 99.39%Color and Shape:SolidMolecular weight:419.31GGTI298 Trifluoroacetate
CAS:GGTI298 trifluoroacetate (GGTI298TFA salt) is a geranylgeranyltransferase I inhibitor that causes cell cycle arrest and induces apoptosis.Formula:C27H33N3O3S·C2HF3O2Purity:100% - 98.29%Color and Shape:SolidMolecular weight:593.66ARS-1630
CAS:ARS-1630 is a mutant K-ras G12C inhibitor. It is a less active enantiomer of ARS-1620.Formula:C21H17ClF2N4O2Purity:97.81%Color and Shape:SolidMolecular weight:430.84Ref: TM-T10376
1mg52.00€5mg117.00€10mg170.00€25mg325.00€50mg469.00€100mg615.00€1mL*10mM (DMSO)134.00€SOS2 ligand 1
CAS:SOS2 ligand 1 (compound 2) is a selective ligand for son of sevenless 2 (SOS2), exhibiting a KD value of 4.6 µM.Formula:C19H21N5OColor and Shape:SolidMolecular weight:335.403ML141
CAS:ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).Formula:C22H21N3O3SPurity:99.36% - 99.56%Color and Shape:SolidMolecular weight:407.49Ref: TM-T2463
1mg39.00€2mg50.00€5mg72.00€10mg110.00€25mg225.00€50mg406.00€100mg582.00€500mg1,254.00€1mL*10mM (DMSO)74.00€ESI-08
CAS:ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.Formula:C20H23N3OSPurity:99.05%Color and Shape:SolidMolecular weight:353.48NSC 23766 trihydrochloride
CAS:NSC 23766 trihydrochloride (Rac1 Inhibitor) is an inhibitor of Rac GTPase targeting Rac activation by GEFs; no inhibitory for RhoA or Cdc42.Formula:C24H35N7·3HClPurity:96.48% - 99.54%Color and Shape:SolidMolecular weight:530.96MBQ-167
CAS:MBQ-167 is a dual inhibitor of Rac/Cdc42 (IC50s: 103 nM for Rac 1/2/3 and 78 nM for Cdc42 in MDA-MB-231 cells, respectively).Formula:C22H18N4Purity:98.07% - 98.74%Color and Shape:SolidMolecular weight:338.41Ref: TM-T16021
1mg37.00€2mg52.00€5mg79.00€10mg111.00€25mg208.00€50mg376.00€100mg567.00€1mL*10mM (DMSO)87.00€SOS1-IN-17
SOS1-IN-17 (Compound 8d) is an orally active inhibitor targeting the SOS1-KRASG12C interaction, with an IC50 of 5.1 nM. It suppresses ERK phosphorylation in DLD-1 cells with an IC50 of 18 nM and demonstrates antiproliferative activity in KRASG12C-mutant Mia-Paca-2 cells, with an IC50 of 0.11 μM. In mouse models, SOS1-IN-17 shows antitumor efficacy against pancreatic cancer.Formula:C29H34F3N5O2Color and Shape:SolidMolecular weight:541.61Rasarfin
CAS:Rasarfin inhibits Ras and ARF6.Formula:C23H24ClN3O3Purity:97.98%Color and Shape:SolidMolecular weight:425.91Ref: TM-T9407
1mg40.00€5mg80.00€10mg116.00€25mg205.00€50mg340.00€100mg485.00€200mg655.00€1mL*10mM (DMSO)88.00€CCG-222740
CAS:CCG-222740 is an inhibitor of Rho/MRTF pathwayFormula:C23H19ClF2N2O3Purity:98.76%Color and Shape:SolidMolecular weight:444.86Ref: TM-T7764
2mg42.00€5mg65.00€10mg99.00€25mg182.00€50mg279.00€100mg414.00€200mg587.00€1mL*10mM (DMSO)70.00€6H05
CAS:6H05 (K-Ras inhibitor) is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C).Formula:C20H30ClN3O2S3Purity:98%Color and Shape:SolidMolecular weight:476.12KRAS inhibitor-32
CAS:KRAS inhibitor-32 (compound 139A) is a KRAS inhibitor utilized in cancer research.Formula:C29H35FN10OS2Color and Shape:SolidMolecular weight:622.78Adagrasib
CAS:View and buy Adagrasib (MRTX849) from TargetMol.MRTX849 is a potent, selective and covalent KRASG12C inhibitor with potential antineoplastic activity. Cited in 2 publications.Formula:C32H35ClFN7O2Purity:99.10% - 99.9%Color and Shape:SolidMolecular weight:604.12LUNA18
CAS:LUNA18 is an orally active inhibitor targeting KRAS, exhibiting potent activity with an IC50 value of less than 2 nM against the KRAS G12D-SOS mutation.Formula:C73H105F5N12O12Purity:98%Color and Shape:SolidMolecular weight:1437.68KRas G12C inhibitor 4
CAS:KRas G12C inhibitor 4 is a compound that inhibits KRas G12C.Formula:C33H38ClN7O2Purity:98%Color and Shape:SolidMolecular weight:600.15NHTD
CAS:NHTD, a KRAS-PDEδ inhibitor, exerts its function by targeting the isoprenyl binding pocket of PDEδ, which alters the cellular localization of KRAS. This modification restricts the proliferation of cancer cells with KRAS mutations and induces cell apoptosis (Apoptosis). NHTD is utilized in the study of KRAS-driven non-small cell lung cancer (NSCLC).Formula:C24H26N2O5Color and Shape:SolidMolecular weight:422.47Atranorin
CAS:Atranorin has antinociceptive, anti-inflammatory, can be pro-oxidant or antioxidant, and protects cells from H(2)O(2)-induced oxidative stress.Formula:C19H18O8Purity:98% - 99.57%Color and Shape:SolidMolecular weight:374.34
