Raf
Raf kinases are key components of the MAPK/ERK signaling pathway, playing a critical role in transmitting signals from the cell membrane to the nucleus. Raf activation leads to the phosphorylation of MEK, which subsequently activates ERK, influencing cell division, differentiation, and survival. Mutations in Raf, particularly in B-Raf, are associated with various cancers, making Raf a critical target in cancer therapy. At CymitQuimica, we provide a variety of Raf inhibitors and modulators to support your research in oncology, signal transduction, and therapeutic development.
Products of "Raf"
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Rineterkib
CAS:Rineterkib (ERK-IN-1) is an inhibitor of RAF and ERK1/2 activating mutations in the MAPK pathway.Formula:C26H27BrF3N5O2Purity:98.4%Color and Shape:SolidMolecular weight:578.42Ref: TM-T11224
1mg95.00€5mg188.00€10mg354.00€25mg597.00€50mg852.00€100mg1,159.00€1mL*10mM (DMSO)249.00€ZM 336372
CAS:ZM 336372 is a potent and selective c-Raf inhibitor.Formula:C23H23N3O3Purity:97.24% - 97.51%Color and Shape:SolidMolecular weight:389.45B-Raf IN 11
CAS:B-Raf IN 11 is a novel selective inhibitor.Formula:C17H14BrF2N3O3SPurity:99.46%Color and Shape:SolidMolecular weight:458.28K-Ras-IN-1
CAS:K-Ras-IN-1 is a K-Ras inhibitor.Formula:C11H13NOSPurity:98.72%Color and Shape:SolidMolecular weight:207.29Ref: TM-T5469
2mg46.00€5mg70.00€10mg101.00€25mg182.00€50mg284.00€100mg424.00€200mg588.00€1mL*10mM (DMSO)77.00€LXH254
CAS:LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.Cost-effective and quality-assured.Formula:C25H25F3N4O4Purity:98.3% - 99.92%Color and Shape:SolidMolecular weight:502.49Ref: TM-T11898
1mg52.00€5mg122.00€10mg185.00€25mg363.00€50mg567.00€100mg690.00€200mg948.00€500mg1,444.00€1mL*10mM (DMSO)135.00€PROTAC B-Raf degrader 1
CAS:PROTAC B-Raf degrader 1 is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf,PROTAC B-Raf degrader 1 With anti-cancer activity.Formula:C36H37N5O12SPurity:98%Color and Shape:SolidMolecular weight:763.77Anti-Phospho-RAF1 (Ser259) Antibody (5X237)
Anti-Phospho-RAF1 (Ser259) Antibody (5X237) is an antibody targeting Phospho-RAF1 (Ser259). Anti-Phospho-RAF1 (Ser259) Antibody (5X237) can be used in ELISA, WB, IHC, IF.Color and Shape:Odour LiquidKobe2602
CAS:Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities.Formula:C14H9F4N5O4SPurity:98.36% - 99.39%Color and Shape:SolidMolecular weight:419.31Sulindac sulfide
CAS:Sulindac sulfide: NSAID targeting COX-1, inhibits Ras-Raf-1 and gamma-secretase (IC50: 20.2 μM), active sulinic acid metabolite.Formula:C20H17FO2SPurity:99.68%Color and Shape:SolidMolecular weight:340.41RAS GTPase inhibitor 1
CAS:RAS GTPase inhibitor 1 is a RAS GTPase inhibitor with potential antitumor activity.Formula:C27H28ClF4N5O2Purity:99.66%Color and Shape:SolidMolecular weight:565.99NSC-70220
CAS:SOS1-IN-1 is an inhibitor of SOS1.Formula:C22H15NO2Purity:98%Color and Shape:SolidMolecular weight:325.36Raf inhibitor 3
CAS:Raf inhibitor 3 (Example 30), a potent inhibitor of both B-Raf and C-Raf, exhibits IC50 values below 15 nM. It is applicable in cancer research studies [1].Formula:C18H19FN8O2SPurity:98%Color and Shape:SolidMolecular weight:430.46B-Raf IN 13
CAS:B-Raf IN 13 is a potent B-Raf inhibitor with anticancer activity.B-Raf IN 13 has an IC50 of 3.55 nM in the BRAF V600E enzyme assay.Formula:C19H19ClFN3O4SPurity:95.83% - 98.39%Color and Shape:SoildMolecular weight:439.89Xl-281
CAS:XL-281: potent oral RAF kinase inhibitor, effective on wild-type and mutants, reduces tumor growth and cell proliferation, increases apoptosis.Formula:C24H19ClN4O4Purity:95.77% - 98.60%Color and Shape:SolidMolecular weight:462.89MCP110
CAS:MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors.Formula:C33H36N2O3Purity:97.18%Color and Shape:OilMolecular weight:508.65Ref: TM-T24437
1mg37.00€5mg97.00€10mg169.00€25mg291.00€50mg423.00€100mg562.00€500mg1,121.00€1mL*10mM (DMSO)108.00€6H05
CAS:6H05 (K-Ras inhibitor) is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C).Formula:C20H30ClN3O2S3Purity:98%Color and Shape:SolidMolecular weight:476.12Raf inhibitor 2
CAS:Raf inhibitor 2 (CID 25014542) is novel inhibitor of Raf kinases.Formula:C15H8Br2ClNO2Purity:98.53%Color and Shape:SolidMolecular weight:429.49Ref: TM-T4194
2mg40.00€5mg62.00€10mg96.00€25mg164.00€50mg240.00€100mg349.00€200mg492.00€1mL*10mM (DMSO)64.00€Raf inhibitor 1 dihydrochloride
CAS:Raf inhibitor 1 dihydrochloride (B-Raf inhibitor 1 dihydrochloride) is a potent and selective B-Raf inhibitor.Formula:C26H19ClN8HClPurity:98.19% - 98.44%Color and Shape:SolidMolecular weight:551.86Ref: TM-T4167
1mg49.00€2mg64.00€5mg103.00€10mg180.00€25mg300.00€50mg445.00€100mg652.00€500mg1,378.00€1mL*10mM (DMSO)188.00€SGX-523
CAS:SGX-523 is a selective Met inhibitor (IC50: 4 nM), no inhibitory to Abl, BRAFV599E, p38α, and c-Raf.Formula:C18H13N7SPurity:100% - 99.49%Color and Shape:SolidMolecular weight:359.41Effusanin A
CAS:Effusanin A: antibacterial, damages DNA, inhibits DU145 cells at 3.16 μM and LoVo cells at 3.02 μM.Formula:C20H28O5Purity:98.00%Color and Shape:SolidMolecular weight:348.43
