Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC
- Adiponectin receptor
- ATPase
- Calcium Channel
- CFTR
- CGRP Receptor
- Chloride channel
- GABA Receptor
- Monoamine Transporter
- Monocarboxylate transporter
- Na-K-Cl cotransporter
- NKCC
- NPC1L1
- OAT
- OCT
- P-gp
- Potassium Channel
- Proton pump
- SGLT
- Sodium Channel
- TRP/TRPV Channel
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Products of "Membrane Transporter/Ion Channel"
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Branaplam
CAS:Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.Formula:C22H27N5O2Purity:97.81% - 99.73%Color and Shape:SolidMolecular weight:393.48TRPV4 agonist-1
CAS:TRPV4 agonist-1 is an agonist of TRPV4 (EC50: 60 nM in the hTRPV4 Ca2+ assay).Formula:C25H23ClF2N4O2Purity:98%Color and Shape:SolidMolecular weight:484.93BKCa activator-1
BKCa activator-1 (Compound 51b) is an orally active activator of BKCa calcium-activated potassium channels with an EC50 of 2.82 μM. It promotes K+ efflux, leading to cell membrane hyperpolarization and inhibition of smooth muscle contraction. In a spontaneous hypertensive rat (SHR) model, it alleviates urinary incontinence and exhibits antitussive effects in a guinea pig cough model.Formula:C22H23F7N2O3Color and Shape:SolidMolecular weight:496.418Cycloartane-3,24,25-triol
CAS:Cycloartane-3,24,25-triol has potential for development as an anti-cancer agent against prostate cancer.Formula:C30H52O3Purity:98%Color and Shape:SolidMolecular weight:460.743Basmisanil
CAS:Basmisanil (RG1662) is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for theFormula:C21H20FN3O5SPurity:99.21% - ≥98%Color and Shape:SolidMolecular weight:445.46Ref: TM-T7165
2mg38.00€5mg56.00€10mg79.00€25mg123.00€50mg197.00€100mg376.00€500mg847.00€1mL*10mM (DMSO)52.00€ML418
CAS:ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.Formula:C19H24ClN3O3Purity:99.30%Color and Shape:SolidMolecular weight:377.87Ref: TM-T16110
1mg39.00€5mg84.00€10mg117.00€25mg188.00€50mg304.00€100mg437.00€200mg615.00€1mL*10mM (DMSO)93.00€Riluzole hydrochloride
CAS:Riluzole hydrochloride, an anticonvulsant Na+ channel blocker, inhibits GABA uptake (IC50: 43 µM).Formula:C8H6ClF3N2OSPurity:99.76%Color and Shape:SolidMolecular weight:270.665-Fluoromethylornithine dihydrochloride
CAS:5-Fluoromethylornithine dihydrochloride (5-FMOrn dihydrochloride) is an OAT inhibitor and OAT inactivator, which can be used to study metabolic diseases.Formula:C6H15Cl2FN2O2Purity:90%Color and Shape:SolidMolecular weight:237.1µ-Conotoxin-CnIIIC acetate
µ-Conotoxin-CnIIIC acetate is a NaV1.4 sodium channel antagonist, a conotoxin peptide consisting of 22 amino acids, used for muscle relaxation and pain relief.Formula:C92H139N35O28S6·xC2H4O2Purity:99.94%Color and Shape:SolidMolecular weight:2375.70 (free base)6,8-Diprenylnaringenin
CAS:6,8-Diprenylnaringenin (Senegalensin) is a natural product from hop Humulus lupulus.Formula:C25H28O5Purity:98%Color and Shape:SolidMolecular weight:408.49Dotinurad
CAS:Dotinurad ((3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone) is a potent agent of uricosuric (IC50: 3.6 μM for uric acid).Formula:C14H9Cl2NO4SPurity:97.43% - 98.95%Color and Shape:SolidMolecular weight:358.2Ref: TM-T15160
1mg130.00€5mg305.00€10mg472.00€25mg778.00€50mg1,035.00€100mg1,415.00€1mL*10mM (DMSO)240.00€Bupivacaine hydrochloride
CAS:Bupivacaine hydrochloride (Vivacaine) is a long-lasting, amide local anesthetic that blocks sodium channels, inhibiting nerve impulses and sensation.Formula:C18H28N2O·HClPurity:100% - 100%Color and Shape:SolidMolecular weight:324.89Pipequaline
CAS:Pipequaline (PK-8165) is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. It possesses a novel chemical structure that is not closely related to other drugs of this type. The drug has a similar pharmacological profile to the benzodiazepine family of drugs, but with mainly anxiolytic properties and very little sedative, amnestic or anticonvulsant effects, and so is classified as a nonbenzodiazepine anxiolytic.Formula:C22H24N2Purity:98%Color and Shape:SolidMolecular weight:316.44NS1652
CAS:NS1652 is an anion conductance inhibitor. NS1652 blocks chloride channel has an IC50 of 1.6 μM in human and mouse red blood cells.Formula:C15H11F3N2O3Purity:99.62%Color and Shape:SolidMolecular weight:324.25NS5806
CAS:NS5806 activates K+ currents, slows KV4.2/4.3 decay with KChIP2, and boosts KV4.3/KChIP2 peaks (EC50=5.3μM).Formula:C16H8Br2F6N6OPurity:97.95%Color and Shape:SolidMolecular weight:574.07Valbenazine tosylate
CAS:Valbenazine tosylate, the tosylate salt of valbenazine, is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying noFormula:C38H54N2O10S2Purity:98%Color and Shape:SolidMolecular weight:762.97Acetoxyvalerensre
CAS:Acetoxyvalerensre (acetylvalerenolic acid) (acetylvalerenolic acid) is a derivative of valerenic acid, which is a a GABAA receptor modulator.Formula:C17H24O4Purity:98.22%Color and Shape:SolidMolecular weight:292.37Bendroflumethiazide
CAS:Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)Formula:C15H14F3N3O4S2Purity:98% - 99.94%Color and Shape:Crystals From Dioxane SolidMolecular weight:421.41Nav1.8-IN-1
CAS:Nav1.8-IN-1 (CHEMBL1270208) is an inhibitor of human NaV1.8Formula:C20H15ClF3N3O2Purity:97.59%Color and Shape:SolidMolecular weight:421.8Ref: TM-T8579
1mg88.00€5mg170.00€10mg259.00€25mg425.00€50mg598.00€100mg810.00€200mg1,074.00€1mL*10mM (DMSO)197.00€4-Hydroxytolbutamide
CAS:4-Hydroxytolbutamide is a drug metabolite derived from the metabolism of Tolbutamide by CYP2C8 and CYP2C9 a sulfonylurea hypoglycemic agent.Formula:C12H18N2O4SPurity:98%Color and Shape:White To Off-WhiteMolecular weight:286.35Cholesterol myristate
CAS:Cholesterol myristate, a natural steroid in Chinese medicine, affects GABAA, nicotinic receptors, and potassium channels.Formula:C41H72O2Purity:99.65%Color and Shape:SolidMolecular weight:597.01(E)-3,4,5-Trimethoxycinnamic acid
CAS:(E)-3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) is a natural product from the roots and rhizomes of Notopterygium incisum.Formula:C12H14O5Purity:99.83%Color and Shape:SolidMolecular weight:238.24GNE-131
CAS:GNE-131 is a potent and specific inhibitor of human sodium channel NaV1.7 (IC50: 3 nM).Formula:C23H30N4O3SPurity:98.54% - 99.59%Color and Shape:SolidMolecular weight:442.57Ref: TM-TQ0014
1mg120.00€5mg264.00€10mg376.00€25mg630.00€50mg880.00€100mg1,169.00€1mL*10mM (DMSO)283.00€PF-04885614
CAS:PF-04885614 is a potent inhibitor of NaV1.8, has potential for neurological and neurodevelopmental diseases treatment.Formula:C13H14F3N3OPurity:98.02%Color and Shape:SolidMolecular weight:285.27Ref: TM-T12421
1mg48.00€2mg65.00€5mg96.00€10mg153.00€25mg283.00€50mg527.00€100mg743.00€500mg1,568.00€1mL*10mM (DMSO)96.00€GX-674
CAS:GX-674 is a highly potent and selective voltage-gated sodium channel 1.7 (Nav1.7) antagonist with an IC50 value of 0.1 nM measured at -40 mV for the study ofFormula:C21H13ClF2N6O3S2Purity:98%Color and Shape:SolidMolecular weight:534.95LTGO-33
CAS:LTGO-33 is a voltage-gated sodium channel NaV1.8 inhibitor that inhibits NaV1.8, NaV1.1-NaV1.7, and NaV1.9.Formula:C21H17F4N3O3SPurity:97.60%Color and Shape:SoildMolecular weight:467.44Myomodulin acetate(110570-93-9 free base)
Myomodulin acetate is present in two identified aplysia neurons that contain myomodulin A the ARC motor neuron B16 and the abdominal neuron L10.Formula:C38H71N11O10S2Purity:99.24%Color and Shape:SolidMolecular weight:906.17VU591 hydrochloride
CAS:VU591 hydrochloride is a selective Kir1.1 (ROMK) blocker with IC50 of 0.24 μM, not affecting Kir7.1, Kir2.1, Kir2.3, or Kir4.1, similar to VU 590.Formula:C16H13ClN6O5Purity:98.93% - 99.22%Color and Shape:SolidMolecular weight:404.76Ref: TM-T13320
1mg35.00€5mg74.00€10mg111.00€25mg226.00€50mg386.00€100mg540.00€200mg735.00€1mL*10mM (DMSO)84.00€Isonipecotic acid
CAS:Isonipecotic acid (4-Piperidinecarboxylic acid) is a heterocyclic compound. Isonipecotic acid mainly characterized as a GABAA receptor partial agonist.Formula:C6H11NO2Purity:99.82%Color and Shape:White To Faint Pink-Beige PowderMolecular weight:129.16Piperazine citrate
CAS:Piperazine citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring.Formula:C24H46N6O14Purity:≥98%Color and Shape:Crystals IndicationMolecular weight:642.65Blebbistatin
CAS:Blebbistatin ((±)-Blebbistatin) is a non-muscle myosin II (NMII)-selective and non-muscle myosin heavy chain 9 (MYH9)-specific inhibitor.Cost-effective and quality-assured.Formula:C18H16N2O2Purity:99.88% - 99.97%Color and Shape:Bright Yellow SolidMolecular weight:292.33Ref: TM-T21550
1mg35.00€2mg52.00€5mg77.00€10mg131.00€25mg215.00€50mg378.00€100mg568.00€1mL*10mM (DMSO)86.00€Antidepressant agent 8
CAS:Antidepressant agent 8 (Compound 1f) acts as a selective antagonist for the NMDA receptor GluN1/2A (NMDA receptorGluN1/2A), with an IC50 of 2.94 μmol/L. In a hydrocortisone-induced zebrafish depression model, it demonstrates antidepressant-like effects and shows good blood-brain barrier penetration.Formula:C18H23FN4OS2Color and Shape:SolidMolecular weight:394.53P2X4 antagonist-3
P2X4 antagonist-3 (Compound 14c) is a P2X4 inhibitor with an IC50 value of 1.2 μM. It holds potential for research into neuroinflammation, chronic pain, and cancer progression.Formula:C19H20FN3O4Color and Shape:SolidMolecular weight:373.38Org 25543
CAS:Org 25543 is the development of an N-Acyl amino acid that selectively inhibits the glycine transporter 2 to produce analgesia in a rat model of chronic pain.Formula:C24H32N2O4Purity:99.13%Color and Shape:SolidMolecular weight:412.52Ref: TM-T50082
1mg84.00€5mg167.00€10mg250.00€25mg414.00€50mg562.00€100mg787.00€200mg1,035.00€1mL*10mM (DMSO)187.00€Lorediplon
CAS:Lorediplon is a novel hypnotic drug acting as a GABAA receptor modulator, differentially active at the α1-subunit, associated with promoting sleep.Formula:C20H15FN4O2SPurity:99.12% - 99.19%Color and Shape:SolidMolecular weight:394.42Sipatrigine
CAS:Sipatrigine (619C89) is an inhibitor of glutamate release, TREK ion channels, TRESK channels, sodium channels, and calcium channels.Formula:C15H16Cl3N5Purity:100% - 99.49%Color and Shape:SolidMolecular weight:372.68Ref: TM-T16887
1mg96.00€5mg202.00€10mg303.00€25mg507.00€50mg730.00€100mg1,026.00€200mg1,378.00€1mL*10mM (DMSO)224.00€Crofelemer
CAS:Crofelemer (Provir) is an orally active antidiarrheal agent. It targets the cystic fibrosis transmembrane conductance regulator (CFTR) and calcium-activated chloride channels (CACC), which are responsible for chloride and fluid secretion in the gastrointestinal tract. Crofelemer is applicable for research in diarrhea-related conditions.Color and Shape:SolidEvenamide
CAS:Evenamide (NW-3509) is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness.Formula:C16H26N2O2Purity:96.74% - 99.15%Color and Shape:SolidMolecular weight:278.39Ref: TM-T15260
1mg44.00€5mg93.00€10mg135.00€25mg264.00€50mg420.00€100mg677.00€200mg935.00€1mL*10mM (DMSO)93.00€Omeprazole metabolite Omeprazole sulfone
CAS:Omeprazole metabolite Omeprazole sulfone can inhibit proton pump.Formula:C17H19N3O4SPurity:99.61%Color and Shape:SolidMolecular weight:361.42Ref: TM-T12309
1mg49.00€2mg65.00€5mg97.00€10mg154.00€25mg298.00€50mg445.00€100mg642.00€500mg1,320.00€1mL*10mM (DMSO)120.00€Fosphenytoin disodium
CAS:Fosphenytoin disodium (ACC-9653) is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blockerFormula:C16H13N2Na2O6PPurity:99.97%Color and Shape:White Crystalline PowderMolecular weight:406.24ICA-105574
CAS:ICA-105574 activates hERG, enhancing peak current and shortening action potential, while modulating activation kinetics.Formula:C19H14N2O4Purity:98.89%Color and Shape:SolidMolecular weight:334.33Ref: TM-T9009
1mg43.00€5mg92.00€10mg144.00€25mg298.00€50mg469.00€100mg687.00€200mg938.00€1mL*10mM (DMSO)97.00€Heteropodatoxin-1
Heteropodatoxin-1 (HpTx1), a spider peptide toxin, acts as an inhibitor of the Kv4.2 current, while concurrently inhibiting Nav1.7 and activating Nav1.9Formula:C168H238N46O51S6Purity:98%Color and Shape:SolidMolecular weight:3910.35VU0463271
CAS:VU0463271: KCC2 antagonist, IC50 61 nM, >100x selective over NKCC1, inactive on other GPCRs, channels, transporters.Formula:C19H18N4OS2Purity:99.75%Color and Shape:SolidMolecular weight:382.5Rilmakalim
CAS:Rilmakalim is a potassium channel opener. Rilmakalim shows antivasoconstrictor effect.Formula:C21H23NO5SPurity:100% - 99.63%Color and Shape:SolidMolecular weight:401.48NMDA agonist 2
NMDA agonist 2 (compound 8d) effectively inhibits NMDA receptors, exhibiting an EC50 of 0.034 μM for GluN1/2C. It plays a significant role in neurological and psychiatric disorders.Formula:C14H12BrFN2O3SMolecular weight:387.224(-)-Denudatin B
CAS:Denudatin B, from Magnolia fargesii, inhibits platelets via phosphoinositide breakdown blockage.Formula:C21H24O5Purity:97.45%Color and Shape:SolidMolecular weight:356.41Bicuculline
CAS:Bicuculline, a plant-derived GABAA receptor antagonist, identified in 1932, reacts to light.Formula:C20H17NO6Purity:98% - ≥98%Color and Shape:Light Yellow PowderMolecular weight:367.35Tenapanor
CAS:Tenapanor (RDX 5791), an NHE3 inhibitor, regulates sodium in the gut and kidney with a strong preclinical safety record and minimal side effects.Formula:C50H66Cl4N8O10S2Purity:98.08% - 99.49%Color and Shape:SolidMolecular weight:1145.05Paxilline
CAS:Paxilline, an indole alkaloid mycotoxin from Penicillium paxilli, is a specific inhibitor of BK-type K(+) channels with anticonvulsant activity.Formula:C27H33NO4Purity:98%Color and Shape:White PowderMolecular weight:435.56TRPV3 antagonist 74a
CAS:TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological disorders.Formula:C17H17F3N2O2Purity:≥98.0%Color and Shape:SolidMolecular weight:338.32µ-Conotoxin SIIIA
CAS:μ-Conotoxin SIIIA, a tetrodotoxin (TTX)-resistant sodium channel blocker, is a toxic peptide derived from Conus snail venom.Formula:C83H123N33O27S6Purity:98%Color and Shape:SolidMolecular weight:2207.46DFP00173
CAS:DFP00173: Potent, selective AQP3 inhibitor; IC50 ~0.1-0.4 μM; less effective on AQP7, AQP9.Formula:C11H7Cl2N3O3SPurity:99.15% - 99.55%Color and Shape:SolidMolecular weight:332.16Ref: TM-T11014
1mg77.00€5mg169.00€10mg255.00€25mg420.00€50mg562.00€100mg787.00€200mg1,064.00€1mL*10mM (DMSO)182.00€Phlotoxin-1
Phlotoxin-1 (PhlTx1), a 34-amino acid peptide featuring three disulfide bridges, is derived from the Phlogiellus genus spider and acts as an antinociceptiveFormula:C183H254N46O48S6Purity:98%Color and Shape:SolidMolecular weight:4058.64Divalproex Sodium
CAS:Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted byFormula:C8H16O2·C8H15O2·NaPurity:99.84%Color and Shape:A White Powder With A Characteristic OdorMolecular weight:310.41Ref: TM-T6474
10mg39.00€25mg55.00€50mg79.00€100mg116.00€200mg188.00€500mg335.00€1mL*10mM (DMSO)55.00€ONO-8590580
CAS:ONO-8590580 (CS-2894) is a negative allosteric modulator of GABAA α5.Formula:C21H21FN6Purity:99.43%Color and Shape:SolidMolecular weight:376.43Ref: TM-TQ0040
1mg66.00€2mg93.00€5mg126.00€10mg170.00€25mg376.00€50mg562.00€100mg802.00€1mL*10mM (DMSO)140.00€Eact
CAS:Eact is a potent TMEM16A activator that also triggers TRPV1, causing itch, pain, and heat sensitivity.Formula:C22H24N2O5SPurity:97.01%Color and Shape:SolidMolecular weight:428.5Ref: TM-T15192
1mg37.00€2mg50.00€5mg79.00€10mg126.00€25mg254.00€50mg429.00€100mg632.00€200mg899.00€1mL*10mM (DMSO)87.00€PPQ-102
CAS:PPQ-102 (CFTR Inhibitor), an effective CFTR inhibitor, can completely inhibit CFTR chloride current (IC50: 90 nM).Formula:C26H22N4O3Purity:99.17% - ≥95%Color and Shape:SolidMolecular weight:438.48Ref: TM-T1874
1mg40.00€2mg51.00€5mg85.00€10mg135.00€25mg269.00€50mg520.00€100mg745.00€1mL*10mM (DMSO)93.00€JC-229
CAS:JC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. JC-229 can be used to study human African Trypanosomiasis (HAT).Formula:C20H14Cl4N2O3SPurity:97.14%Color and Shape:SolidMolecular weight:504.21ANO1-IN-4
CAS:ANO1-IN-4 (Compound 10bm) is a reversible inhibitor of the calcium-activated chloride channel transmembrane protein 16A (TMEM16A, also known as ANO1), with an IC50 of 0.030 µM. It demonstrates good metabolic stability in rat liver microsomes and can inhibit spontaneous contractions in isolated mouse ileum.Formula:C19H19BrF2N2O2SColor and Shape:SolidMolecular weight:457.33Lasiodiplodin
CAS:Lasiodiplodin may have potential anti-inflammatory activity, it shows moderate suppression effects on induced NO production.Formula:C17H24O4Purity:98%Color and Shape:SolidMolecular weight:292.37AMG2850
CAS:AMG2850 is a potent, orally bioavailable, and selective antagonist of transient receptor potential melastatin 8 (TRPM8).Formula:C19H17F6N3OPurity:99.05%Color and Shape:SolidMolecular weight:417.35Ref: TM-T10300
1mg74.00€5mg170.00€10mg248.00€25mg445.00€50mg662.00€100mg848.00€1mL*10mM (DMSO)182.00€Fenbufen
CAS:Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis.Formula:C16H14O3Purity:98.35% - 98.46%Color and Shape:White SolidMolecular weight:254.28DNDS
CAS:DNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).Formula:C14H8N2Na2O10S2Purity:99.88%Color and Shape:Physical Description White Powder (Ntp 1992)Molecular weight:474.33Indican
CAS:Indican (Indoxyl-β-D-glucoside) is a natural protective compound that is used to protect the liver.Formula:C14H17NO6Purity:99.92% - ≥98%Color and Shape:White To Off-White Crystalline PowderMolecular weight:295.29BAPTA-AM
CAS:BAPTA-AM is a calcium chelator that is cell-permeable and selective, blocking hERG, hKv1.3, and hKv1.5 channels (IC50=1.3/1.45/1.23 μM).Formula:C34H40N2O18Purity:98% - 99.47%Color and Shape:White Powder Or Crystalline PowderMolecular weight:764.68Broflanilide
CAS:Broflanilide metabolite desmethyl-broflanilide blocks GABA receptor in dieldrin-resistant insects, inhibiting S. litura at IC50 1.3 nM.Formula:C25H14BrF11N2O2Purity:98.95%Color and Shape:SolidMolecular weight:663.29Ref: TM-T10618
1mg52.00€2mg74.00€5mg111.00€10mg180.00€25mg358.00€50mg588.00€100mg835.00€1mL*10mM (DMSO)131.00€GW 542573X
CAS:GW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.GW 542573X induces a leftward shift in the Ca2+ response curveFormula:C19H28N2O5Purity:99.91%Color and Shape:SolidMolecular weight:364.44Progabide
CAS:Progabide (SL 76002) is an agonist of the gamma-aminobutyric acid receptor.Formula:C17H16ClFN2O2Purity:99.7%Color and Shape:SolidMolecular weight:334.77Slotoxin
Slotoxin, a peptide extracted from the venom of the Centruroides noxius Hoffmann scorpion, inhibits high-conductance calcium-activated potassium channels with aFormula:C177H275N47O50S7Purity:98%Color and Shape:SolidMolecular weight:4085.82Desalkylgidazepam
CAS:Desalkylgidazepam, a benzodiazepine compound, is a metabolite of gidazepam. It is capable of activating both GABA A-type receptors and the translocator protein (TSPO).Formula:C15H11BrN2OColor and Shape:SolidMolecular weight:315.17ICA
CAS:ICA (N-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinamine) is a SK channel inhibitor and exhibits antileishmanial activity (IC50: 2.1 µM).Formula:C13H10N4SPurity:99.66%Color and Shape:SolidMolecular weight:254.31Ref: TM-T15546
1mg96.00€5mg170.00€10mg255.00€25mg409.00€50mg567.00€100mg792.00€200mg1,064.00€1mL*10mM (DMSO)238.00€TC-I2000
CAS:TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells with IC50 of 53 nM.Formula:C23H18F4N2OPurity:98.87%Color and Shape:SolidMolecular weight:414.4Tracazolate hydrochloride
CAS:Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity.Formula:C16H25ClN4O2Purity:99.07%Color and Shape:SolidMolecular weight:340.85Mitiglinide calcium hydrate
CAS:Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes.Formula:C38H52CaN2O8Purity:100% - 99.73%Color and Shape:White SolidMolecular weight:704.91GsAF-II
GsAF-II is a peptide toxin that selectively blocks hERG1 subtype potassium channels through a voltage-dependent mechanism and impedes Nav1.x subtype sodiumFormula:C176H261N47O45S7Purity:98%Color and Shape:SolidMolecular weight:3979.7Psora 4
CAS:Psora 4 (5-(4-Phenylbutoxy)psoralen) is a Kv1.3 blocker and a caloric restriction mimetic.Formula:C21H18O4Color and Shape:SolidMolecular weight:334.37Ursodeoxycholic acid
CAS:Ursodeoxycholic acid (UDCA) can be used to dissolve gallstones and reduce cholesterol absorption.Formula:C24H40O4Purity:99.74% - ≥95%Color and Shape:White - Almost White Solid PowderMolecular weight:392.57GABA receptor Antagonist 1
GABA receptor Antagonist 1 (compound 7w) effectively inhibits the Px RDL1 GABAR at an IC50 of 7.08 nmol/L and demonstrates insecticidal efficacy against P.Purity:98%Color and Shape:Odour Solidπ-TRTX-Hm3a
π-TRTX-Hm3a, a 37-amino acid peptide derived from the venom of the Togo starburst tarantula (Heteroscodra maculata), selectively inhibits the acid-sensing ionFormula:C186H290N56O49S6Purity:98%Color and Shape:SolidMolecular weight:4287.03Nav1.8-IN-4
CAS:Nav1.8-IN-4 is a potent Nav1.8 channel inhibitor with potential analgesic activity.Nav1.8-IN-4 can be used for pain and neurological related disorders.Formula:C20H14F4N2O3Purity:99.83%Color and Shape:SoildMolecular weight:406.33Ref: TM-T77693
1mg59.00€2mg85.00€5mg125.00€10mg188.00€25mg376.00€50mg612.00€100mg938.00€500mg1,882.00€Vesnarinone HCl
Vesnarinone HCl is an oral PDE3 inhibitor improving heart contractility, affecting calcium and potassium flux. Used in heart failure research.Formula:C22H26ClN3O4Purity:99.17%Color and Shape:SoildMolecular weight:431.91Lanatoside C
CAS:Lanatoside C, a cardiac glycoside, treats heart failure and arrhythmia; taken orally or IV.Formula:C49H76O20Purity:100% - 99.8%Color and Shape:SolidMolecular weight:985.12Pramocaine hydrochloride
CAS:Pramocaine hydrochloride (Pramoxine HCl), a topical anesthetic, is served as an antipruritic.Formula:C17H27NO3·HClPurity:99.15% - 99.61%Color and Shape:Crystals White Or Off White Crystalline PowderMolecular weight:329.86ML204
CAS:ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.Formula:C15H18N2Purity:98.1% - 99.72%Color and Shape:SolidMolecular weight:226.32Ref: TM-T2298
2mg35.00€5mg50.00€10mg74.00€25mg111.00€50mg145.00€100mg220.00€200mg284.00€500mg467.00€1mL*10mM (DMSO)52.00€BMS-394136
CAS:BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.Formula:C24H21Cl2FN4OPurity:98.25% - 98.67%Color and Shape:SolidMolecular weight:471.35Dc1a
Dc1a, a toxin isolated from the desert bush spider Diguetia canities [1], potently facilitates the opening of the German cockroach Na v channel (BgNa v 1).Formula:C276H414N76O84S8Purity:98%Color and Shape:SolidMolecular weight:6397.22Leptomycin A
CAS:Leptomycin A from Streptomyces inhibits CRM1, reducing HIV-1 replication, less potent than Leptomycin B, blocks protein nuclear export.Formula:C32H46O6Purity:98%Color and Shape:SolidMolecular weight:526.7PF 05089771 tosylate
CAS:PF-05089771 inhibits Nav1.7 channels (IC50: 11-33 nM), selective over Nav1.1-1.6/1.8, Ca+, K+ channels, TRPV1; 1000x affinity for half-inactivated state.Formula:C18H12Cl2FN5O3S2·C7H8O3SPurity:97.76%Color and Shape:SolidMolecular weight:672.56ASP7663
CAS:ASP7663 is a TRPA1 Receptor Agonist and exhibiting an abdominal analgesic effect in vivo.Formula:C14H14FNO3Purity:98.61%Color and Shape:SolidMolecular weight:263.26Ciclopirox
CAS:Ciclopirox is an antifungal that chelates Fe3+ and Al3+, inhibiting enzymes and has antibacterial and anti-inflammatory effects.Formula:C12H17NO2Purity:97.72% - 99.41%Color and Shape:SolidMolecular weight:207.27Clamikalant sodium
CAS:Clamikalant sodium (HMR 1098) is an ATP-dependent potassium channel (KATP) cardiac-selective blocker, used in the study of arrhythmias.Formula:C19H21ClN3NaO5S2Purity:99.95%Color and Shape:SolidMolecular weight:493.96Ref: TM-T63330
1mg52.00€5mg100.00€10mg191.00€25mg384.00€50mg595.00€100mg969.00€200mg1,296.00€1mL*10mM (DMSO)105.00€AVE-0118
CAS:AVE-0118 is a potassium channel blocker and suppresses persistent atrial fibrillation.Formula:C30H29N3O3Purity:98.89% - 99.52%Color and Shape:SolidMolecular weight:479.57Ref: TM-T26689
1mg73.00€5mg139.00€10mg183.00€25mg320.00€50mg474.00€100mg688.00€500mg1,444.00€1mL*10mM (DMSO)168.00€Pivagabine
CAS:Pivagabine (CXB-722), a 4-aminobutyric acid derivative, modulates GABA, CRF, and crosses the rat blood-brain barrier.Formula:C9H17NO3Purity:99.87%Color and Shape:SolidMolecular weight:187.24Ref: TM-T12492
1mg35.00€2mg48.00€5mg70.00€10mg104.00€25mg167.00€50mg249.00€100mg369.00€500mg837.00€1mL*10mM (DMSO)50.00€Nisoxetine hydrochloride
CAS:Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitorFormula:C17H21NO2·HClPurity:98.52%Color and Shape:White SolidMolecular weight:307.82δ-Theraphotoxin-Hm1b
δ-Theraphotoxin-Hm1b, a 42-amino acid peptide derived from the Togo starburst tarantula (Heteroscodra maculata) venom, selectively inhibits the inactivation ofFormula:C169H241N45O50S6Purity:98%Color and Shape:SolidMolecular weight:3895.38Linoleoyl glycine
CAS:Linoleoyl glycine activates hKCNQ1/hKCNE1 channels, has analgesic properties, and is found in skin, spinal cord, and brain.Formula:C20H35NO3Purity:98.96%Color and Shape:SolidMolecular weight:337.5RY785
CAS:RY785 is a potent and selective inhibitor of voltage-gated potassium channel such as KV2.2 (IC50 = 50 nM). RY785 may be used in pain relief studies.Formula:C21H20N4O2SPurity:98.04%Color and Shape:SolidMolecular weight:392.47Ref: TM-T12786
1mg51.00€5mg144.00€10mg235.00€25mg399.00€50mg560.00€100mg787.00€200mg1,093.00€1mL*10mM (DMSO)131.00€Retusin
CAS:Retusin is derived from the leaves of Talinum triangulare. Retusin Retusin can be used in studies about acting as pre- and postemergent herbicides.Formula:C19H18O7Purity:99.00%Color and Shape:SolidMolecular weight:358.34VU590
CAS:VU590 is an inhibitor of extrarenal medullary potassium ROMK.VU590 inhibits Kir7.1 and modulates uterine myometrial contractility and melanocortin signalling.Formula:C24H32N4O7Purity:98.06%Color and Shape:SolidMolecular weight:488.53MZ82
MZ82, a derivative of Ko 143, is a potent inhibitor of ATP-binding cassette sub-family G member 2 (ABCG2/BCRP), with an IC50 of approximately 23 nM. Compared to Ko 143, MZ82 exhibits significantly enhanced metabolic stability in liver microsomes and shows marked improvement in mice, along with the ability to penetrate the brain.Formula:C26H29N3O3Color and Shape:SolidMolecular weight:431.53
