Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC
- Adiponectin receptor
- ATPase
- Calcium Channel
- CFTR
- CGRP Receptor
- Chloride channel
- GABA Receptor
- Monoamine Transporter
- Monocarboxylate transporter
- Na-K-Cl cotransporter
- NKCC
- NPC1L1
- OAT
- OCT
- P-gp
- Potassium Channel
- Proton pump
- SGLT
- Sodium Channel
- TRP/TRPV Channel
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Products of "Membrane Transporter/Ion Channel"
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ICA-105574
CAS:ICA-105574 activates hERG, enhancing peak current and shortening action potential, while modulating activation kinetics.Formula:C19H14N2O4Purity:98.89%Color and Shape:SolidMolecular weight:334.33Ref: TM-T9009
1mg43.00€5mg92.00€10mg144.00€25mg298.00€50mg469.00€100mg687.00€200mg938.00€1mL*10mM (DMSO)97.00€Heteropodatoxin-1
Heteropodatoxin-1 (HpTx1), a spider peptide toxin, acts as an inhibitor of the Kv4.2 current, while concurrently inhibiting Nav1.7 and activating Nav1.9Formula:C168H238N46O51S6Purity:98%Color and Shape:SolidMolecular weight:3910.35VU0463271
CAS:VU0463271: KCC2 antagonist, IC50 61 nM, >100x selective over NKCC1, inactive on other GPCRs, channels, transporters.Formula:C19H18N4OS2Purity:99.75%Color and Shape:SolidMolecular weight:382.5Rilmakalim
CAS:Rilmakalim is a potassium channel opener. Rilmakalim shows antivasoconstrictor effect.Formula:C21H23NO5SPurity:100% - 99.63%Color and Shape:SolidMolecular weight:401.48NMDA agonist 2
NMDA agonist 2 (compound 8d) effectively inhibits NMDA receptors, exhibiting an EC50 of 0.034 μM for GluN1/2C. It plays a significant role in neurological and psychiatric disorders.Formula:C14H12BrFN2O3SMolecular weight:387.224(-)-Denudatin B
CAS:Denudatin B, from Magnolia fargesii, inhibits platelets via phosphoinositide breakdown blockage.Formula:C21H24O5Purity:97.45%Color and Shape:SolidMolecular weight:356.41Bicuculline
CAS:Bicuculline, a plant-derived GABAA receptor antagonist, identified in 1932, reacts to light.Formula:C20H17NO6Purity:98% - ≥98%Color and Shape:Light Yellow PowderMolecular weight:367.35Tenapanor
CAS:Tenapanor (RDX 5791), an NHE3 inhibitor, regulates sodium in the gut and kidney with a strong preclinical safety record and minimal side effects.Formula:C50H66Cl4N8O10S2Purity:98.08% - 99.49%Color and Shape:SolidMolecular weight:1145.05Paxilline
CAS:Paxilline, an indole alkaloid mycotoxin from Penicillium paxilli, is a specific inhibitor of BK-type K(+) channels with anticonvulsant activity.Formula:C27H33NO4Purity:98%Color and Shape:White PowderMolecular weight:435.56TRPV3 antagonist 74a
CAS:TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological disorders.Formula:C17H17F3N2O2Purity:≥98.0%Color and Shape:SolidMolecular weight:338.32µ-Conotoxin SIIIA
CAS:μ-Conotoxin SIIIA, a tetrodotoxin (TTX)-resistant sodium channel blocker, is a toxic peptide derived from Conus snail venom.Formula:C83H123N33O27S6Purity:98%Color and Shape:SolidMolecular weight:2207.46DFP00173
CAS:DFP00173: Potent, selective AQP3 inhibitor; IC50 ~0.1-0.4 μM; less effective on AQP7, AQP9.Formula:C11H7Cl2N3O3SPurity:99.15% - 99.55%Color and Shape:SolidMolecular weight:332.16Ref: TM-T11014
1mg77.00€5mg169.00€10mg255.00€25mg420.00€50mg562.00€100mg787.00€200mg1,064.00€1mL*10mM (DMSO)182.00€Phlotoxin-1
Phlotoxin-1 (PhlTx1), a 34-amino acid peptide featuring three disulfide bridges, is derived from the Phlogiellus genus spider and acts as an antinociceptiveFormula:C183H254N46O48S6Purity:98%Color and Shape:SolidMolecular weight:4058.64Divalproex Sodium
CAS:Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted byFormula:C8H16O2·C8H15O2·NaPurity:99.84%Color and Shape:A White Powder With A Characteristic OdorMolecular weight:310.41Ref: TM-T6474
10mg39.00€25mg55.00€50mg79.00€100mg116.00€200mg188.00€500mg335.00€1mL*10mM (DMSO)55.00€ONO-8590580
CAS:ONO-8590580 (CS-2894) is a negative allosteric modulator of GABAA α5.Formula:C21H21FN6Purity:99.43%Color and Shape:SolidMolecular weight:376.43Ref: TM-TQ0040
1mg66.00€2mg93.00€5mg126.00€10mg170.00€25mg376.00€50mg562.00€100mg802.00€1mL*10mM (DMSO)140.00€Eact
CAS:Eact is a potent TMEM16A activator that also triggers TRPV1, causing itch, pain, and heat sensitivity.Formula:C22H24N2O5SPurity:97.01%Color and Shape:SolidMolecular weight:428.5Ref: TM-T15192
1mg37.00€2mg50.00€5mg79.00€10mg126.00€25mg254.00€50mg429.00€100mg632.00€200mg899.00€1mL*10mM (DMSO)87.00€PPQ-102
CAS:PPQ-102 (CFTR Inhibitor), an effective CFTR inhibitor, can completely inhibit CFTR chloride current (IC50: 90 nM).Formula:C26H22N4O3Purity:99.17% - ≥95%Color and Shape:SolidMolecular weight:438.48Ref: TM-T1874
1mg40.00€2mg51.00€5mg85.00€10mg135.00€25mg269.00€50mg520.00€100mg745.00€1mL*10mM (DMSO)93.00€JC-229
CAS:JC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. JC-229 can be used to study human African Trypanosomiasis (HAT).Formula:C20H14Cl4N2O3SPurity:97.14%Color and Shape:SolidMolecular weight:504.21ANO1-IN-4
CAS:ANO1-IN-4 (Compound 10bm) is a reversible inhibitor of the calcium-activated chloride channel transmembrane protein 16A (TMEM16A, also known as ANO1), with an IC50 of 0.030 µM. It demonstrates good metabolic stability in rat liver microsomes and can inhibit spontaneous contractions in isolated mouse ileum.Formula:C19H19BrF2N2O2SColor and Shape:SolidMolecular weight:457.33Lasiodiplodin
CAS:Lasiodiplodin may have potential anti-inflammatory activity, it shows moderate suppression effects on induced NO production.Formula:C17H24O4Purity:98%Color and Shape:SolidMolecular weight:292.37
